Multicellular organisms are composed of many different types of cells that cooperate and communicate to form organized systems. In humans there are over 10 trillion cells comprising 200 types of tissues. Each cell originates from a single fertilized egg cell and differentiates through activation of certain genes while others remain inactive, allowing cells to perform specialized functions. Bacteria also regulate genes in response to environmental signals, turning groups on and off. The lac operon in E. coli is a well-studied example of genetic control, where a repressor protein either allows or prevents transcription of genes involved in lactose metabolism depending on the presence of lactose.