1. Repair : Regeneration of injured tissue by parenchymal cells of the same type or replacement by connective tissue. Chapter Three Repair Section A

4. Cell population and cell cycle phases

23. Nerve fiber regeneration Normal nerve fiber Regeneration of Schwann cells and axon filaments at site of nerve lesion or section New axon extending into original channel.

24. 1. Cell-cell interaction Conditioned medium Contact inhibition 2. Growth factors 3. Extracellular matrix Laminin:  Epithelia  Fibroblasts Fibronectin :  Epithelia  Fibroblasts Factors influencing regeneration

26. Cells anchor to dish surface and divide. When cells have formed a complete single layer, they stop dividing. If some cells are scraped away, the remaining cells divide to fill the dish with a single layer and then stop.

45. Granulation tissue : with numerous new blood vessels, fibroblasts and inflammatory cells.

47. Granulation tissue

53. Scar tissue: dense collagen, fibrocytes, scattered fibroblasts and sparse vessels.

60. Healing by First Intention Focal Disruption of Basement Membrane and loss of only a few epithelial cells e.g. Surgical Incision

61. Healing by Second Intention Larger injury, abscess, infarction Process is similar but Results in much larger Scar and then CONTRACTION

63. Healing Skin wound

64. Healing - Skin Scar