2. Lung Cancer
Uncontrolled growth of malignant cells in
one or both lungs and tracheo-bronchial
tree
A result of repeated carcinogenic irritation
causing increased rates of cell replication
Proliferation of abnormal cells leads to
hyperplasia, dysplasia or carcinoma
4. What is the Function of the Lungs?
The lungs consist of five lobes,
three in the right lung and two in
the left lung
Most cells in the lung are epithelial
cells, which line the breathing
passages and produce mucus,
which lubricates and protects the
lungs
The main function of the lungs is
to allow oxygen from the air to
enter the bloodstream for delivery
to the rest of the body
7. Two types of cell Cycle Mechanisms
CDK cycle mechanism-
Ensures well delineated transition bet.
Cell cycle stages
Check- point control mechanism-
sense flaws in DNA replication and
chromosome segregation
8. Risk factors of Lung Cancer
Radiation Exposure
Smoking
Environmental/ Occupational
Exposure
Asbestos
Radon
Passive smoke
9. Smoking Facts
Tobacco use is the
leading cause of lung
cancer
87% of lung cancers
are related to smoking
Risk related to:
age of smoking onset
amount smoked
gender
product smoked
depth of inhalation
40. Where does it travel?
Lymph Nodes, Brain, Liver, Adrenal,
Gland, Bones
40% of metastasis occurs in the
Adrenal Gland
41. How is Lung Cancer Treated?
1.Treatment depends on the stage and type
of lung cancer
2.Surgery
3.Radiation therapy
4.Chemotherapy (options include a
combination of drugs)
5.Targeted therapy
6.Lung cancer is usually treated with a
combination of therapies
42. Cancer Treatment: Surgery
1.The tumor and the nearby lymph nodes in
the chest are typically removed to offer the
best chance for cure
2.For non-small cell lung cancer, a
lobectomy (removal of the entire lobe
where the tumor is located), has shown to
be most effective
3.Surgery may not be possible in some
patients
43. Cancer Treatment: Chemotherapy
1.Drugs used to kill cancer cells
2.A combination of medications is often
used
3.May be prescribed before or after surgery,
or before, during, or after radiation therapy
4.Can improve survival and lessen lung
cancer symptoms in all patients, even
those with widespread lung cancer
44. Cancer Treatment: Radiation
Therapy
1.The use of high-energy x-rays or other
particles to destroy cancer cells
2.Side effects include fatigue, malaise
(feeling unwell), loss of appetite, and skin
irritation at the treatment site
3.Radiation pneumonitis is the irritation and
inflammation of the lung; occurs in 15% of
patients
4.It is important that the radiation treatments
avoid the healthy parts of the lung
45. Lung Cancer Staging
1.Staging is a way of describing a cancer,
such as the size of the tumor and where it
has spread
2.Staging is the most important tool doctors
have to determine a patient’s prognosis
3.The type of treatment a person receives
depends on the stage of the cancer
4.Staging is different for non-small cell lung
cancer and small cell lung cancer
46. Stage I Non-Small Cell Lung Cancer
1.Cancer is found
only in the lung
2.Surgical removal
recommended
3.Radiation therapy
and/or
chemotherapy
may also be used
47. Stage II Non-Small Cell Lung Cancer
1.The cancer has spread
to lymph nodes in the
lung
2.Treatment is surgery to
remove the tumor and
nearby lymph nodes
3.Chemotherapy
recommended; radiation
therapy sometimes
given after
chemotherapy
48. Stage III Non-Small Cell Lung
Cancer
1.The cancer has spread to the lymph
nodes located in the center of the chest,
outside the lung
2.Stage IIIA cancer has spread to lymph
nodes in the chest, on the same side
where the cancer originated
3. Stage IIIB cancer has spread to lymph
nodes on the opposite side of the chest,
under the collarbone, or the pleura
(lining of the chest cavity)
4.Surgery or radiation therapy with
chemotherapy recommended for stage
IIIA
5.Chemotherapy and sometimes radiation
therapy recommended for stage IIIB
49. Stage IV Non-Small Cell Lung Cancer
1.The cancer has spread to
different lobes of the lung
or to other organs, such
as the brain, bones, and
liver
2.Stage IV non-small cell
lung cancer is treated with
chemotherapy
50. Small Cell Lung Cancer–All Stages
1.Patients with limited stage (confined to one area
of the chest) small cell lung cancer are treated
with simultaneous radiation therapy and
chemotherapy
2.Patients with extensive stage (not confined to
one area of the chest) small cell lung cancer are
treated with chemotherapy only
3.Because small cell lung cancer can spread to the
brain, preventative radiation therapy to the brain
is routinely recommended to all patients whose
tumors disappear following chemotherapy and
radiation therapy
51. Nursing responsibilities
Nursing Management during Diagnostic
Phase
1. Obtain nursing history(cough ,
dyspnea , pain or recurrent infection)
2. focus on emotional aspect of
assessment
3. Educate the client with the required
physical care and scheduled examinations
4. Assist to cope with anxiety
52. Nursing management during
Treatment Phase
1. Put great emphasis on assessment of
respiratory system to determine ability of
the client to cope up with surgical
intervention
2. Clients with impaired pulmonary function
may be treated with antibiotics,
bronchodilating medications, and
supervised breathing exercise
53. 3. Encouraged patient to avoid smoking
during preoperative because smoking will
increase pulmonary secretions and
decrease blood oxygen saturation.
4.Assess the clients understanding and
further information as needed
5.Explain the procedure to be done and the
expected outcome
6. Explain and demonstrate post – op
exercises such as leg exercise and correct
posture
54. Postoperative assessments
1.Monitor for signs and symptoms of
respiratory failure
2. Monitor for signs of tension
pneumothorax
3. Observe for subcutaneous emphysema
around incision and in chest and neck
4.Monitor for signs of pulmonary embolism
5. Assess dressing
6. Assess drainage
55. 7. Assess breath sound before and after
coughing
8. Administer pain medication as ordered
9. Allow adequate rest periods
10. Provide client opportunity to ventilate
feelings
56. Nursing Interventions during
Terminal Phase
1. Physical support such as giving of pain
medication should be given great
emphasis.
2.Help the client to ventilate thoughts and
feelings
3. Assist significant others to cope with the
situation