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Bioinformatics
1.
2.
3.
DNA Protein Nucleotides
sequence Gene expression = Protein production
4.
Exons & Introns
STOP F R L
5.
Biological Diversity Bacteria
Fruit Fly Human Yeast
6.
7.
8.
9.
10.
11.
Gene expression Computational
analysis of cDNA microarray expression profiles ~26,000 genes in one experiment
12.
13.
14.
15.
Voronoi Diagram and
Delaunay Triangulation Geometry based approach for functional motifs Discrete Flow
16.
3D alpha shapes
(HIV-1 protease)
17.
18.
19.
Pockets in Ribonuclease
A
20.
A Server for
Identification of Protein Pockets & Cavities CASTp http://cast.engr.uic.edu/ Users of CASTp: Columbia, Harvard, Mayo Clinic, Princeton, Stanford, U Penn, SUNY Stony Brook, Texas A&M, UCIrvine, UBC, Virginia Tech, Yale, Abbott Lab, Pfizer, SmithKline Beecham, ... Agouron, Emisphere, Vertex, ... Kyoto U, Cambridge, European Molecular Biology Lab, INRA (France), Pasteur-Lille, Uppsala, Weizman,... Brazil, Czech, Korea, Turkey, ...
21.
22.
THANK YOU
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