Each lobule comprises cellular plates that radiate from a central vein. Unlike the classical descrip...

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Each lobule comprises cellular plates that radiate from a central vein. Unlike the classical
description where the quadrate lobe belongs to the right lobe, the quadrate lobe is considered to be
a part of left lobe under Couinaud's classification.
The quadrate lobe lies between the fissure for the ligamentum teres (the remnant of the left
umbilical vein of the fetus) and the gallbladder fossa. The left hepatic vein divides the left lobe into
the medial segment and lateral segment, and each of these segments is further divided into inferior
and superior segments. The right hepatic vein divides the right lobe into the anterior segment and
posterior segment, and each of these segments is further divided into inferior and superior
segments.
In 1898, James Cantlie referred to the specific regions of the liver, demarcating them on the basis of
left and right portal structures. However, for the purposes of the surgical resection of the liver, this
anatomical demarcation is not used. The hepatic duct joins the cystic duct from the gallbladder to
form the common bile duct, which drains into the duodenum (the first part of the small intestine).
It extends from the fifth right intercostal space to the right costal margin (the margin of the lowest
rib on the right side). It performs various vital bodily functions ranging from production of bile and
metabolism of carbohydrates, fat, and proteins to detoxification. This wedge-shaped organ is located
in the right upper quadrant of the abdomen.
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