This document discusses drugs that affect the kidney, focusing on diuretics. It describes the five major classes of diuretics and their mechanisms and indications. The classes include thiazides and thiazide-like drugs, loop diuretics, potassium-sparing diuretics, carbonic anhydrase inhibitors, and osmotic diuretics. It also discusses the nursing process for administering diuretics, including assessing patients, monitoring effectiveness, and addressing potential side effects like electrolyte imbalances or hypotension.