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Lower GI bleed
Dr nawin kumar
• as any bleed that occurs distal to the ligament
of Treitz and superior to the anus
• 20-33% of episodes of gastrointestinal (GI)
hemorrhage
– 85% from colon
– 10% from UGI
– 5% from SB
• The mortality rate for LGIB is between 2–4%
• marginal artery of Drummond -
Connects the inferior mesenteric
artery (IMA) with the superior
mesenteric artery (SMA)
• The Arc of Riolan (Riolan's arcade,
Haller's anastomosis or'meandering
mesenteric artery) -connect the
proximal middle colic artery with a
branch of the left colic artery. This
artery is found low in the mesentery,
near the root. It is a poor
anastomosis.
Aetiology
angiodysplasia
carcinoma
Meckel’s diverticulum
intussusception enteritis
Crohn’s disease
carcinoma
proctitis
colitis
carcinoma
polyps
Diverticular
disease
solitary ulcer
haemorrhoids
fissure
carcinoma
warts
Perianal Crohn’s disease
Rule out- Coagulopathy
1. SB
2. Colon
3. Benign anorectal
DANI
Gastrointestinal Hemorrhage
% SMALL BOWEL BLEEDING (5%)
0-40 Angiodysplasias
-10 Erosions or ulcers (potassium, NSAIDs)
-15 Crohn's disease
-10 Radiation
-8 Meckel's diverticulum
-7 Neoplasia
-4 Aortoenteric fistula
-3
• infectious colitis
– E. coli O157:H7
– Shigella
– Salmonella
– Campylobacter
jejuni
• Pseudomembranous
colitis
DANI
• Rectal polyps
• Haemorrhoids
• Anal fissures
• Anal fistulas
• Proctitis
• Gonorrheal or mycoplasmal infections
• Rectal trauma
• Foreign objects
BENIGN ANORECTAL CAUSES
Lower Gastrointestinal Bleeding in Children and
Adolescents
• Intussusception
• Polyps and polyposis syndromes
 Juvenile polyps and polyposis
 Peutz-Jeghers syndrome
 Familial adenomatous polyposis (FAP)
• Inflammatory
 Crohn disease
 Ulcerative colitis
 Indeterminate colitis
• Meckel diverticulum
Clinical Approach
• History
• Physical Examination
• Investigation
• Diagnosis
• Management
History
• Presenting complaint(s)
• History of presenting illness
• Systemic review
• Past medical and surgical history
• Medication history (iatrogenic factors)
• Family history
• Social history
Information about bleeding
• Volume and frequency (amount)of bleeding
• Colour of blood?
• Relationship of bleeding to defecation?
[before, during (mixed into faeces or coating surface?) or after]
• Associatiated symptoms eg, Painful
defecation?, abdominal pain?
amount
• trivial hematochezia to massive hemorrhage
with shock.
BLEEDING
FRANK OCCULT
ANAEMIA
SMALL
BLEED
MASSIVE
BLEED
(rare)
3 groups
Stools may appear red in some patients
after ingestion of beers
Colour- indicate the site
• occult, microscopic bleeding
• Black tarry -melena - usually indicates blood
that has been in the GI tract for at least 8
hours. likely to come UGI
• Maroon color suggests rt. Sided lesion
• Bright red stool- called hematochezia- sign of
a fast moving active GI bleed
Relationship of bleeding to
defecation?
• minor blood on toilet paper
• streaks of bright red blood
• Blood mixed stools
• Slash in pan
• Mixed with mucus
Associated symptoms
• Bloody diarrhoea:
– acute inflammation of the colon; amoebic
colitis; ulcerative colitis; ischaemic colitis;
rectal and colonic carcinoma; shigellosis
•Abdominal pain?
–Carcinoma of the colon; ischaemic colitis (in
elderly(; ulcerative colitis; amoebic colitis
•No abdominal pain?
–Painless bleeding from colonic diverticula,
colonic angiodysplastic lesion; malignant lesion
arising in the rectal ampulla
• anal pain?
– External haemorrhoids; anal fissure, anal ulcer
• Fever?
– Infectious colitis (amoebiasis, shigellosis); ulcerative colitis
• Vomiting of blood
– Bleeding above ligament of Treitz
•A change in your bowel habits?
•A change in the caliber of the stools?
• colo-rectal Carcinoma
• Hypovolaemia
– due to haemorrhage (e.g. pallor, dizziness
hypotension, tachycardia, angina, syncope,
weakness, confusion, stroke, myocardial
infarction/heart attack, and shock)
• Nonspecific complaints
• may include dyspnoea, abdominal pain, chest
pain, fatigue
• past medical history
– constipation or diarrhea- (hemorrhoids, colitis),
– the presence of diverticulosis (diverticular
bleeding),
– receipt of radiation therapy (radiation enteritis),
– recent polypectomy (postpolypectomy bleeding),
and
– vascular disease/hypotension (ischemic colitis).
– anticoagulant
– A family history of colon cancer - colorectal
neoplasm
Investigations &Management
• Resuscitation for major bleeds
• Find site
• Treat the cause
Initial steps in the management of upper gastrointestinal bleeding
Airway protection
Airway monitoring
Endotracheal intubation (if indicated)
Hemodynamic stabilization
Large bore intravenous access
Intravenous fluids
Red cell transfusion (for symptomatic anemia)
Fresh-frozen plasma, platelets (if indicated)
Consider erythropoeitin
Nasogastric oral administration
Large bore orogastric tube/lavage
Clinical and laboratory monitoring
Serial vital signs
Serial hemograms, coagulation profiles, and chemistries (as clinically indicated)
Electrocardiographic monitoring
Hemodynamic monitoring (if indicated in high-risk patients)
Endoscopic examination and therapy
localization
Colour- indicate the site
• occult, microscopic bleeding
• Black tarry -melena - usually indicates blood
that has been in the GI tract for at least 8
hours. likely to come UGI
• Maroon color suggests rt. Sided lesion
• Bright red stool- called hematochezia- sign of
a fast moving active GI bleed
LOCALIZATION
• past medical history
– constipation or diarrhea- (hemorrhoids, colitis),
– the presence of diverticulosis (diverticular
bleeding),
– receipt of radiation therapy (radiation enteritis),
– recent polypectomy (postpolypectomy bleeding),
and
– vascular disease/hypotension (ischemic colitis).
– anticoagulant
– A family history of colon cancer - colorectal
neoplasm
localization
nasogastric
tube
Blood
UGI bleed
bile
UGI bleed-
unlikely
nondiagnostic
(no blood or
bile
LGI bleed
COLONOSCOPY
• Identifies lesion in 75 % or more
• Can provide endoscopic therapyand disadvantages of common diagnostic procedures used in the evaluation of lower
gastrointestinal bleeding
Advantages Disadvantages
• Therapeutic possibilities • Bowel preparation required
• Diagnostic for all sources of
bleeding
• Can be difficult to orchestrate without on-
call endoscopy facilities or staff
• Needed to confirm diagnosis in
most patients regardless of initial
testing
• Invasive
• Efficient/cost-effective
• No bowel preparation needed • Requires active bleeding at the time of the
exam
• Therapeutic possibilities • Less sensitive to venous bleeding
MESENTERIC ANGIOGRAM
• Selective embolization initially controls
hemorrhage in up to 100% of patients, but
rebleeding rates are 15% to 40%
and disadvantages of common diagnostic procedures used in the evaluation of lower
gastrointestinal bleeding
Advantages Disadvantages
• Therapeutic possibilities • Bowel preparation required
• Diagnostic for all sources of
bleeding
• Can be difficult to orchestrate without on-
call endoscopy facilities or staff
• Needed to confirm diagnosis in
most patients regardless of initial
testing
• Invasive
• Efficient/cost-effective
y • No bowel preparation needed • Requires active bleeding at the time of the
exam
• Therapeutic possibilities • Less sensitive to venous bleeding
• May be superior for patients with
severe bleeding
• Diagnosis must be confirmed with
endoscopy/surgery
• Serious complications are possible
e • Noninvasive • Variable accuracy (false positives)
• Sensitive to low rates of bleeding • Not therapeutic
• No bowel preparation • May delay therapeutic intervention
RADIONUCLIDE SCAN
•May be superior for patients with
severe bleeding
•Diagnosis must be confirmed with
endoscopy/surgery
• Seriouscomplications are possible
e •Noninvasive • Variable accuracy(false positives)
• Sensitive to lowratesof bleeding •Nottherapeutic
•No bowel preparation •May delaytherapeutic intervention
•Easilyrepeated if bleeding recurs •Diagnosis must be confirmed with
endoscopy/surgery
py
•Diagnostic andtherapeutic • Visualizesonlythe left colon
Treatment
Lower GI bleed
Small volume Large volume
Investigate cause
Manage cause
Resuscitate
Bleeding
stops
Bleeding
persists
? Surgical
intervention
SURGERY
• two settings: massive or recurrent bleeding.
• Try to localize
– Localisation- segmental rather
– Not localise- blind subtotal colectomy.

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Lower gi bleed neo

  • 1. Lower GI bleed Dr nawin kumar
  • 2. • as any bleed that occurs distal to the ligament of Treitz and superior to the anus • 20-33% of episodes of gastrointestinal (GI) hemorrhage – 85% from colon – 10% from UGI – 5% from SB • The mortality rate for LGIB is between 2–4%
  • 3.
  • 4. • marginal artery of Drummond - Connects the inferior mesenteric artery (IMA) with the superior mesenteric artery (SMA) • The Arc of Riolan (Riolan's arcade, Haller's anastomosis or'meandering mesenteric artery) -connect the proximal middle colic artery with a branch of the left colic artery. This artery is found low in the mesentery, near the root. It is a poor anastomosis.
  • 5. Aetiology angiodysplasia carcinoma Meckel’s diverticulum intussusception enteritis Crohn’s disease carcinoma proctitis colitis carcinoma polyps Diverticular disease solitary ulcer haemorrhoids fissure carcinoma warts Perianal Crohn’s disease
  • 6. Rule out- Coagulopathy 1. SB 2. Colon 3. Benign anorectal DANI
  • 7. Gastrointestinal Hemorrhage % SMALL BOWEL BLEEDING (5%) 0-40 Angiodysplasias -10 Erosions or ulcers (potassium, NSAIDs) -15 Crohn's disease -10 Radiation -8 Meckel's diverticulum -7 Neoplasia -4 Aortoenteric fistula -3
  • 8. • infectious colitis – E. coli O157:H7 – Shigella – Salmonella – Campylobacter jejuni • Pseudomembranous colitis DANI
  • 9. • Rectal polyps • Haemorrhoids • Anal fissures • Anal fistulas • Proctitis • Gonorrheal or mycoplasmal infections • Rectal trauma • Foreign objects BENIGN ANORECTAL CAUSES
  • 10. Lower Gastrointestinal Bleeding in Children and Adolescents • Intussusception • Polyps and polyposis syndromes  Juvenile polyps and polyposis  Peutz-Jeghers syndrome  Familial adenomatous polyposis (FAP) • Inflammatory  Crohn disease  Ulcerative colitis  Indeterminate colitis • Meckel diverticulum
  • 11. Clinical Approach • History • Physical Examination • Investigation • Diagnosis • Management
  • 12. History • Presenting complaint(s) • History of presenting illness • Systemic review • Past medical and surgical history • Medication history (iatrogenic factors) • Family history • Social history
  • 13. Information about bleeding • Volume and frequency (amount)of bleeding • Colour of blood? • Relationship of bleeding to defecation? [before, during (mixed into faeces or coating surface?) or after] • Associatiated symptoms eg, Painful defecation?, abdominal pain?
  • 14. amount • trivial hematochezia to massive hemorrhage with shock.
  • 17. Stools may appear red in some patients after ingestion of beers
  • 18. Colour- indicate the site • occult, microscopic bleeding • Black tarry -melena - usually indicates blood that has been in the GI tract for at least 8 hours. likely to come UGI • Maroon color suggests rt. Sided lesion • Bright red stool- called hematochezia- sign of a fast moving active GI bleed
  • 19. Relationship of bleeding to defecation? • minor blood on toilet paper • streaks of bright red blood • Blood mixed stools • Slash in pan • Mixed with mucus
  • 20. Associated symptoms • Bloody diarrhoea: – acute inflammation of the colon; amoebic colitis; ulcerative colitis; ischaemic colitis; rectal and colonic carcinoma; shigellosis
  • 21. •Abdominal pain? –Carcinoma of the colon; ischaemic colitis (in elderly(; ulcerative colitis; amoebic colitis •No abdominal pain? –Painless bleeding from colonic diverticula, colonic angiodysplastic lesion; malignant lesion arising in the rectal ampulla
  • 22. • anal pain? – External haemorrhoids; anal fissure, anal ulcer
  • 23. • Fever? – Infectious colitis (amoebiasis, shigellosis); ulcerative colitis
  • 24. • Vomiting of blood – Bleeding above ligament of Treitz
  • 25. •A change in your bowel habits? •A change in the caliber of the stools? • colo-rectal Carcinoma
  • 26. • Hypovolaemia – due to haemorrhage (e.g. pallor, dizziness hypotension, tachycardia, angina, syncope, weakness, confusion, stroke, myocardial infarction/heart attack, and shock)
  • 27. • Nonspecific complaints • may include dyspnoea, abdominal pain, chest pain, fatigue
  • 28. • past medical history – constipation or diarrhea- (hemorrhoids, colitis), – the presence of diverticulosis (diverticular bleeding), – receipt of radiation therapy (radiation enteritis), – recent polypectomy (postpolypectomy bleeding), and – vascular disease/hypotension (ischemic colitis). – anticoagulant – A family history of colon cancer - colorectal neoplasm
  • 29. Investigations &Management • Resuscitation for major bleeds • Find site • Treat the cause
  • 30. Initial steps in the management of upper gastrointestinal bleeding Airway protection Airway monitoring Endotracheal intubation (if indicated) Hemodynamic stabilization Large bore intravenous access Intravenous fluids Red cell transfusion (for symptomatic anemia) Fresh-frozen plasma, platelets (if indicated) Consider erythropoeitin Nasogastric oral administration Large bore orogastric tube/lavage Clinical and laboratory monitoring Serial vital signs Serial hemograms, coagulation profiles, and chemistries (as clinically indicated) Electrocardiographic monitoring Hemodynamic monitoring (if indicated in high-risk patients) Endoscopic examination and therapy
  • 32. Colour- indicate the site • occult, microscopic bleeding • Black tarry -melena - usually indicates blood that has been in the GI tract for at least 8 hours. likely to come UGI • Maroon color suggests rt. Sided lesion • Bright red stool- called hematochezia- sign of a fast moving active GI bleed
  • 33. LOCALIZATION • past medical history – constipation or diarrhea- (hemorrhoids, colitis), – the presence of diverticulosis (diverticular bleeding), – receipt of radiation therapy (radiation enteritis), – recent polypectomy (postpolypectomy bleeding), and – vascular disease/hypotension (ischemic colitis). – anticoagulant – A family history of colon cancer - colorectal neoplasm
  • 35.
  • 36.
  • 37. COLONOSCOPY • Identifies lesion in 75 % or more • Can provide endoscopic therapyand disadvantages of common diagnostic procedures used in the evaluation of lower gastrointestinal bleeding Advantages Disadvantages • Therapeutic possibilities • Bowel preparation required • Diagnostic for all sources of bleeding • Can be difficult to orchestrate without on- call endoscopy facilities or staff • Needed to confirm diagnosis in most patients regardless of initial testing • Invasive • Efficient/cost-effective • No bowel preparation needed • Requires active bleeding at the time of the exam • Therapeutic possibilities • Less sensitive to venous bleeding
  • 38. MESENTERIC ANGIOGRAM • Selective embolization initially controls hemorrhage in up to 100% of patients, but rebleeding rates are 15% to 40% and disadvantages of common diagnostic procedures used in the evaluation of lower gastrointestinal bleeding Advantages Disadvantages • Therapeutic possibilities • Bowel preparation required • Diagnostic for all sources of bleeding • Can be difficult to orchestrate without on- call endoscopy facilities or staff • Needed to confirm diagnosis in most patients regardless of initial testing • Invasive • Efficient/cost-effective y • No bowel preparation needed • Requires active bleeding at the time of the exam • Therapeutic possibilities • Less sensitive to venous bleeding • May be superior for patients with severe bleeding • Diagnosis must be confirmed with endoscopy/surgery • Serious complications are possible e • Noninvasive • Variable accuracy (false positives) • Sensitive to low rates of bleeding • Not therapeutic • No bowel preparation • May delay therapeutic intervention
  • 39. RADIONUCLIDE SCAN •May be superior for patients with severe bleeding •Diagnosis must be confirmed with endoscopy/surgery • Seriouscomplications are possible e •Noninvasive • Variable accuracy(false positives) • Sensitive to lowratesof bleeding •Nottherapeutic •No bowel preparation •May delaytherapeutic intervention •Easilyrepeated if bleeding recurs •Diagnosis must be confirmed with endoscopy/surgery py •Diagnostic andtherapeutic • Visualizesonlythe left colon
  • 40. Treatment Lower GI bleed Small volume Large volume Investigate cause Manage cause Resuscitate Bleeding stops Bleeding persists ? Surgical intervention
  • 41. SURGERY • two settings: massive or recurrent bleeding. • Try to localize – Localisation- segmental rather – Not localise- blind subtotal colectomy.