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Author(s): Jonathan D. Trobe, M.D.

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CLINICAL FEATURES OF
   VISUAL AND OCULAR MOTOR
           DISORDERS

               Jonathan D. Trobe, MD
     Departments of Ophthalmology and Neurology
        University of Michigan Medical School




Fall, 2008
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Nikki Selewski
Nikki Selewski
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Nikki Selewski
Nikki Selewski
Image of a
   doctor
performing
  a visual
field exam
    was
 removed.
Image of a
   doctor
performing
  an eye
exam was
 removed.
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Ocular Motor System
1. Move the Eyes from One Equidistant
  Target to Another ( Saccades )
2. Move the Eyes from Distant to Near
  Target or Vice Versa ( Vergence )
3. Keep the Eyes on Target When the
  Target Moves ( Pursuit )
4. Keep the Eyes on Target When the Head
  Moves ( Vestibulo-ocular )
Saccades
1. Voluntary
     a. Move eyes to target seen in peripheral
     field ( visually guided )
     b. Move eyes to unseen target ( non visually
     guided )
2. Involuntary
     a. Rapid eye movements of sleep
     b. Fast phases of nystagmus
     c. Random
Saccades
      Test by having patient fixate a
      stationary target and then look
        from one target to another

Note whether eyes are still during fixation,
  and note speed, amplitude, accuracy of
 refixations, and if oscillations are present
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Saccadic Disorders
1.    Absent (gaze palsy)
2.    Reduced amplitude ( hypometric )
3.    Slow
4.    Inaccurate ( dysmetric )
5.    Intrusive
Vergence
1. Move eyes closer to one another
  ( convergence )

2. Move eyes farther apart from one another
  ( divergence )
Vergence
Test by measuring ocular alignment
      when eyes are focusing
 on a distant and on a near target
Vergence Pathway
1.  Generated in both parieto-occipital
    regions
2.  Travels to midbrain
3.  Exact pathway not known
Vergence Disorders
•    Excessive convergence
•    Insufficient convergence
•    Excessive divergence
•    Insufficient divergence
Vergence Disorders
1. Excessive convergence
      a. Congenital defect
      b. Too much accommodation
      c. Loss of vision
      d. Nonspecific brain insult
2. Insufficient convergence
      a. Idiopathic
      b. Nonspecific brain insult
Vergence Disorders
1.  Excessive Divergence
    a. Congenital defect
    b. Loss of vision

2. Insufficient Divergence
    a. Nonspecific brain insult
Pursuit
       Test by having patient follow
a moving light or finger at about 30 degrees/
                     second

 Note smoothness of motion, amplitude of
    excursion, presence of oscillations
Source Undetermined
Pursuit Disorders
1.  Cogwheel ( saccadic )
2.  Absent
Vestibulo-ocular
In awake patients with intact voluntary eye
  movements, can test only with special
  techniques
Vestibulo-ocular
In comatose patients and in awake patients with
  poor voluntary eye movements, two tests:
  1. Doll s Head Maneuver. Move head rapidly and
  look for slow contraversive conjugate eye
  movements
  2. Cold Water Calorics. Look for ipsiversive slow
  conjugate eye movements and perhaps
  contraversive involuntary saccades
  ( nystagmus )
Source Undetermined
Vestibulo-ocular Disorders
•  General hypofunction (creates oscillopsia)
•  Imbalance (creates nystagmus)
Supranuclear Gaze Palsy
•  Absent voluntary gaze (saccades and
   pursuit)
•  Intact reflex gaze (vestibulo-ocular),
   elicited by Doll s Head Maneuver or Cold
   Water Calorics
•  Means that brain stem gaze pathways are
   intact but cerebral gaze pathways are not
   intact
Additional Source Information
                  for more information see: http://open.umich.edu/wiki/CitationPolicy

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Slide 6 – Mountain View Nikki Selewski Creative Commons Attribution License
http://creativecommons.org/licenses/by/3.0/
Slide 7 – Blurry Mountain View Nikki Selewski Creative Commons Attribution License
http://creativecommons.org/licenses/by/3.0/
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Slide 12 – Obstructed Mountain View Nikki Selewski Creative Commons Attribution License
http://creativecommons.org/licenses/by/3.0/
Slide 13 – Half of a Mountain View Nikki Selewski Creative Commons Attribution License
http://creativecommons.org/licenses/by/3.0/
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                for more information see: http://open.umich.edu/wiki/CitationPolicy
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11.17.08: Clinical Features of Visual and Ocular Motor Disorders

  • 1. Author(s): Jonathan D. Trobe, M.D. License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/education/about/ terms-of-use. Any medical information in this material is intended to inform and educate and is not a tool for self- diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  • 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  • 3. CLINICAL FEATURES OF VISUAL AND OCULAR MOTOR DISORDERS Jonathan D. Trobe, MD Departments of Ophthalmology and Neurology University of Michigan Medical School Fall, 2008
  • 14. Image of a doctor performing a visual field exam was removed.
  • 15. Image of a doctor performing an eye exam was removed.
  • 30. Ocular Motor System 1. Move the Eyes from One Equidistant Target to Another ( Saccades ) 2. Move the Eyes from Distant to Near Target or Vice Versa ( Vergence ) 3. Keep the Eyes on Target When the Target Moves ( Pursuit ) 4. Keep the Eyes on Target When the Head Moves ( Vestibulo-ocular )
  • 31. Saccades 1. Voluntary a. Move eyes to target seen in peripheral field ( visually guided ) b. Move eyes to unseen target ( non visually guided ) 2. Involuntary a. Rapid eye movements of sleep b. Fast phases of nystagmus c. Random
  • 32. Saccades Test by having patient fixate a stationary target and then look from one target to another Note whether eyes are still during fixation, and note speed, amplitude, accuracy of refixations, and if oscillations are present
  • 37. Saccadic Disorders 1.  Absent (gaze palsy) 2.  Reduced amplitude ( hypometric ) 3.  Slow 4.  Inaccurate ( dysmetric ) 5.  Intrusive
  • 38. Vergence 1. Move eyes closer to one another ( convergence ) 2. Move eyes farther apart from one another ( divergence )
  • 39. Vergence Test by measuring ocular alignment when eyes are focusing on a distant and on a near target
  • 40. Vergence Pathway 1.  Generated in both parieto-occipital regions 2.  Travels to midbrain 3.  Exact pathway not known
  • 41. Vergence Disorders •  Excessive convergence •  Insufficient convergence •  Excessive divergence •  Insufficient divergence
  • 42. Vergence Disorders 1. Excessive convergence a. Congenital defect b. Too much accommodation c. Loss of vision d. Nonspecific brain insult 2. Insufficient convergence a. Idiopathic b. Nonspecific brain insult
  • 43. Vergence Disorders 1.  Excessive Divergence a. Congenital defect b. Loss of vision 2. Insufficient Divergence a. Nonspecific brain insult
  • 44. Pursuit Test by having patient follow a moving light or finger at about 30 degrees/ second Note smoothness of motion, amplitude of excursion, presence of oscillations
  • 46. Pursuit Disorders 1.  Cogwheel ( saccadic ) 2.  Absent
  • 47. Vestibulo-ocular In awake patients with intact voluntary eye movements, can test only with special techniques
  • 48. Vestibulo-ocular In comatose patients and in awake patients with poor voluntary eye movements, two tests: 1. Doll s Head Maneuver. Move head rapidly and look for slow contraversive conjugate eye movements 2. Cold Water Calorics. Look for ipsiversive slow conjugate eye movements and perhaps contraversive involuntary saccades ( nystagmus )
  • 50. Vestibulo-ocular Disorders •  General hypofunction (creates oscillopsia) •  Imbalance (creates nystagmus)
  • 51. Supranuclear Gaze Palsy •  Absent voluntary gaze (saccades and pursuit) •  Intact reflex gaze (vestibulo-ocular), elicited by Doll s Head Maneuver or Cold Water Calorics •  Means that brain stem gaze pathways are intact but cerebral gaze pathways are not intact
  • 52. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicy Slide 4 – Source Undetermined Slide 5 – Source Undetermined Slide 6 – Mountain View Nikki Selewski Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Slide 7 – Blurry Mountain View Nikki Selewski Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Slide 8 – Source Undetermined Slide 9 – Source Undetermined Slide 10 – Source Undetermined Slide 11 – Source Undetermined Slide 12 – Obstructed Mountain View Nikki Selewski Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Slide 13 – Half of a Mountain View Nikki Selewski Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Slide 16 – Source Undetermined Slide 17 – Source Undetermined Slide 18 – Source Undetermined Slide 19 – Source Undetermined Slide 20 – Source Undetermined Slide 21 – Source Undetermined Slide 22 – Source Undetermined Slide 23 – Source Undetermined
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