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Project: Ghana Emergency Medicine Collaborative
Document Title: Skin Infections
Author(s): Katherine Perry (University of Michigan), RN BSN 2012
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Lice	
  
•  Lice	
  are	
  parasi,c	
  insects	
  that	
  can	
  be	
  found	
  on	
  
people's	
  heads,	
  and	
  bodies	
  
•  Human	
  lice	
  survive	
  by	
  feeding	
  on	
  human	
  blood	
  
•  Lice	
  found	
  on	
  each	
  area	
  of	
  the	
  body	
  are	
  different	
  
from	
  each	
  other.	
  The	
  three	
  types	
  of	
  lice	
  that	
  live	
  
on	
  humans	
  are:	
  
–  Pediculus	
  humanus	
  capi/s	
  (head	
  louse)	
  
–  Pediculus	
  humanus	
  corporis	
  (body	
  louse,	
  clothes	
  
louse)	
  and	
  
–  Pthirus	
  pubis	
  ("crab"	
  louse,	
  pubic	
  louse)	
  
3	
  
Lice	
  
•  Lice	
  infesta,ons	
  (pediculosis	
  and	
  pthiriasis)	
  are	
  spread	
  most	
  
commonly	
  by	
  close	
  person-­‐to-­‐person	
  contact	
  
•  Found	
  mainly	
  in	
  children	
  who	
  go	
  to	
  school,	
  especially	
  just	
  aIer	
  the	
  
holidays	
  
•  Are	
  found	
  in	
  both	
  clean	
  and	
  dirty	
  hair	
  
•  Feed	
  on	
  human	
  blood	
  
•  Do	
  not	
  always	
  cause	
  itching	
  
•  Cannot	
  be	
  killed	
  by	
  regular	
  shampoos	
  but	
  can	
  be	
  eliminated	
  by	
  
using	
  special	
  head	
  lice	
  medica,on	
  
•  Do	
  not	
  transmit	
  diseases	
  
•  Do	
  not	
  live	
  on	
  pets	
  
4	
  
Symptoms	
  
•  Itching	
  is	
  hallmark	
  symptom	
  caused	
  by	
  allergic	
  
reac,on	
  
•  Lice	
  bite	
  the	
  skin	
  and	
  feed	
  on	
  person’s	
  skin	
  
which	
  leads	
  to	
  allergic	
  reac,on	
  and	
  itching	
  

5	
  
Head	
  Lice	
  
•  Head	
  lice	
  and	
  their	
  eggs	
  (nits)	
  can	
  be	
  seen	
  on	
  hair,	
  
nape	
  of	
  the	
  neck	
  and	
  behind	
  ears	
  	
  
•  They	
  can	
  vary	
  in	
  color	
  from	
  white	
  to	
  brown	
  to	
  dark	
  
grey	
  	
  
•  Eggs	
  are	
  ,ny	
  round	
  	
  or	
  oval	
  that	
  are	
  ,ghtly	
  aSached	
  
to	
  the	
  hair	
  near	
  scalp	
  

6	
  
Head	
  Lice	
  

Wellcome Images, Wellcome Images

7	
  
Pubic	
  Lice	
  
•  Itching	
  around	
  the	
  genitals	
  as	
  well	
  as	
  the	
  anus,	
  
armpits,	
  eyelashes,	
  and	
  other	
  body	
  areas	
  with	
  
hair	
  
•  	
  Pubic	
  lice	
  bites	
  may	
  cause	
  small,	
  flat,	
  blue-­‐
gray	
  marks	
  (maculae	
  cerulea)	
  that	
  look	
  like	
  
bruises	
  on	
  torso,	
  thighs	
  or	
  upper	
  arm	
  	
  
•  Pubic	
  lice	
  that	
  infect	
  eyelashes	
  &	
  eyelids	
  may	
  
cause	
  irrita,on	
  and	
  crus,ng	
  in	
  those	
  areas	
  	
  
•  Pubic	
  lice	
  tends	
  to	
  spread	
  by	
  sexual	
  contact	
  
8	
  
Kauczuk, Wikimedia Commons

9	
  
Body	
  Lice	
  
•  Itchy	
  sores	
  usually	
  develop	
  in	
  the	
  armpits,	
  
around	
  the	
  waist,	
  and	
  along	
  the	
  trunk	
  where	
  
seams	
  of	
  clothes	
  press	
  against	
  the	
  skin	
  
•  The	
  lice	
  and	
  eggs	
  are	
  generally	
  not	
  seen	
  on	
  
the	
  skin	
  but	
  may	
  be	
  found	
  in	
  the	
  seams	
  of	
  the	
  
person's	
  clothing.	
  

10	
  
Treatment	
  
•  Check	
  for	
  live	
  lice	
  and	
  nits	
  
•  Work	
  in	
  strong	
  light	
  and	
  sec,on	
  the	
  hair.	
  Use	
  a	
  
fine-­‐tooth	
  comb	
  (a	
  pet	
  flea	
  comb	
  works	
  well)	
  to	
  
find	
  the	
  insects	
  and	
  to	
  comb	
  them	
  out	
  if	
  possible;	
  
or	
  remove	
  them	
  using	
  tweezers	
  
•  Adult	
  lice	
  are	
  reddish-­‐brown;	
  nits	
  are	
  white	
  or	
  
clear	
  and	
  adhere	
  to	
  the	
  hair	
  shaI.	
  They	
  do	
  not	
  
jump	
  or	
  fly	
  
•  Medicated	
  shampoo,	
  	
  cream	
  rinse,	
  or	
  lo,on	
  to	
  
kill	
  the	
  lice	
  
11	
  
Treatment	
  
•  Medicated	
  lice	
  treatments	
  usually	
  kill	
  the	
  lice	
  and	
  nits,	
  but	
  it	
  may	
  take	
  a	
  few	
  
days	
  for	
  the	
  itching	
  to	
  stop.	
  For	
  very	
  resistant	
  lice,	
  an	
  oral	
  medica,on	
  might	
  
be	
  prescribed.	
  
•  Follow	
  the	
  direc,ons	
  exactly	
  because	
  these	
  products	
  are	
  insec,cides	
  
•  Applying	
  too	
  much	
  medica,on	
  —	
  or	
  using	
  it	
  too	
  frequently	
  —	
  can	
  increase	
  
the	
  risk	
  of	
  causing	
  harm.	
  Follow	
  the	
  direc,ons	
  on	
  the	
  product	
  label	
  to	
  ensure	
  
that	
  the	
  treatment	
  works	
  properly.	
  

12	
  
Treatment	
  	
  
•  Treatment	
  may	
  be	
  unsuccessful	
  if	
  the	
  
medica,on	
  is	
  not	
  used	
  correctly	
  or	
  if	
  the	
  lice	
  
are	
  resistant	
  to	
  it	
  
•  	
  AIer	
  treatment,	
  your	
  doctor	
  may	
  suggest	
  
combing	
  out	
  the	
  nits	
  with	
  a	
  fine-­‐tooth	
  comb	
  
and	
  also	
  may	
  recommend	
  repea,ng	
  
treatment	
  in	
  7	
  to	
  10	
  days	
  to	
  kill	
  any	
  newly	
  
hatched	
  nits.	
  
Priwo, Wikimedia13	
  
Commons
Treatment	
  
•  Check	
  everyone	
  in	
  the	
  household.	
  Lice	
  are	
  very	
  
contagious	
  
•  Wash	
  all	
  bedding,	
  recently	
  used	
  towels	
  and	
  
recently	
  worn	
  clothing	
  in	
  hot	
  water,	
  and	
  dry	
  
them	
  in	
  a	
  hot	
  dryer	
  
•  	
  Soak	
  all	
  combs	
  and	
  brushes	
  in	
  hot	
  water	
  for	
  at	
  
least	
  10	
  minutes	
  
•  Treat	
  eyelashes	
  and	
  eyebrows	
  with	
  a	
  thick	
  layer	
  
of	
  petroleum	
  jelly.	
  Apply	
  twice	
  a	
  day	
  for	
  8	
  days.	
  
Never	
  use	
  any	
  chemical	
  treatment	
  on	
  eyelashes	
  
or	
  eyebrows	
  
14	
  
Scabies	
  
•  Easily	
  spread	
  skin	
  disease	
  caused	
  by	
  a	
  very	
  
small	
  species	
  of	
  mite	
  

Kalumet, Wikimedia Commons

15	
  
Scabies	
  
•  Eight-­‐legged	
  mite	
  causes	
  scabies	
  in	
  humans	
  is	
  microscopic	
  
•  The	
  female	
  mite	
  burrows	
  just	
  beneath	
  your	
  skin	
  and	
  
produces	
  a	
  tunnel	
  in	
  which	
  it	
  deposits	
  eggs	
  
•  Eggs	
  mature	
  in	
  21	
  days,	
  and	
  the	
  new	
  mites	
  work	
  their	
  way	
  
to	
  the	
  surface	
  of	
  your	
  skin,	
  where	
  they	
  mature	
  and	
  can	
  
spread	
  to	
  other	
  areas	
  of	
  your	
  skin	
  or	
  to	
  the	
  skin	
  of	
  other	
  
people	
  
•  Close	
  physical	
  contact	
  and,	
  less	
  oIen,	
  sharing	
  clothing	
  or	
  
bedding	
  with	
  an	
  infected	
  person	
  can	
  spread	
  the	
  mites.	
  
•  Dogs,	
  cats	
  and	
  humans	
  all	
  are	
  affected	
  by	
  their	
  own	
  dis,nct	
  
species	
  of	
  mite.	
  Each	
  species	
  of	
  mite	
  prefers	
  one	
  specific	
  
type	
  of	
  host	
  and	
  doesn't	
  live	
  long	
  away	
  from	
  that	
  preferred	
  
host.	
  
16	
  
Scabies	
  Symptoms	
  
•  Mites	
  that	
  cause	
  scabies	
  burrow	
  into	
  the	
  skin	
  and	
  deposit	
  
their	
  eggs,	
  forming	
  a	
  burrow	
  that	
  looks	
  like	
  a	
  pencil	
  mark	
  
•  Eggs	
  mature	
  in	
  21	
  days	
  
•  Itching,	
  Rashes,	
  Sores	
  (abrasions)	
  on	
  the	
  skin	
  from	
  
scratching	
  and	
  digging	
  
•  Thin,	
  	
  pencil-­‐mark	
  lines	
  on	
  the	
  skin	
  
•  Mites	
  may	
  be	
  more	
  widespread	
  on	
  a	
  baby's	
  skin,	
  causing	
  
pimples	
  over	
  the	
  trunk,	
  or	
  small	
  blisters	
  over	
  palms	
  or	
  
soles	
  
•  In	
  young	
  children,	
  the	
  head,	
  neck,	
  shoulders,	
  palms,	
  and	
  
soles	
  are	
  involved.	
  
•  In	
  older	
  children	
  and	
  adults,	
  the	
  hands,	
  wrists,	
  genitals,	
  
and	
  abdomen	
  are	
  involved.	
  

17	
  
Complica9ons	
  of	
  Scabies	
  
•  A	
  more	
  severe	
  form	
  of	
  scabies,	
  called	
  crusted	
  
scabies,	
  may	
  affect	
  certain	
  high-­‐risk	
  groups,	
  
including:	
  
–  People	
  with	
  chronic	
  health	
  condi,ons	
  that	
  weaken	
  the	
  
immune	
  system,	
  such	
  as	
  HIV	
  or	
  chronic	
  leukemia	
  
–  People	
  who	
  are	
  very	
  ill,	
  such	
  as	
  people	
  in	
  hospitals	
  or	
  
nursing	
  facili,es	
  
–  Crusted	
  scabies	
  tends	
  to	
  be	
  crusty	
  and	
  scaly,	
  and	
  covers	
  
large	
  areas	
  of	
  the	
  body.	
  It's	
  very	
  contagious	
  and	
  can	
  be	
  
hard	
  to	
  treat	
  
18	
  
Scabies	
  Diagnosis	
  
•  The	
  microscopic	
  examina,on	
  can	
  determine	
  
the	
  presence	
  of	
  mites	
  or	
  their	
  eggs	
  

Michael Geary, Wikimedia Commons

19	
  
Treatment	
  
•  Permethrin	
  5	
  percent	
  (Elimite)	
  -­‐	
  twice,	
  with	
  a	
  week	
  or	
  so	
  
between	
  each	
  applica,on.	
  Permethrin	
  is	
  generally	
  
considered	
  safe	
  for	
  children	
  and	
  adults	
  of	
  all	
  ages,	
  
including	
  women	
  who	
  are	
  pregnant	
  or	
  nursing.	
  
•  Lindane	
  -­‐	
  usually	
  applied	
  in	
  two	
  treatments,	
  spaced	
  about	
  
a	
  week	
  apart.	
  This	
  medica,on	
  isn't	
  safe	
  for	
  children	
  
younger	
  than	
  age	
  2	
  years,	
  women	
  who	
  are	
  pregnant	
  or	
  
nursing,	
  or	
  people	
  with	
  weakened	
  immune	
  systems.	
  
•  Crotamiton	
  (Eurax)	
  -­‐	
  nonchemical	
  medica,on	
  is	
  applied	
  
once	
  a	
  day	
  for	
  two	
  to	
  five	
  days	
  
•  Although	
  these	
  medica,ons	
  kill	
  the	
  mites	
  promptly,	
  you	
  
may	
  find	
  that	
  the	
  itching	
  doesn't	
  stop	
  en,rely	
  for	
  several	
  
weeks	
  
20	
  
Isola9on	
  Precau9ons	
  
•  Contact	
  precau,ons	
  with	
  protec,ve	
  garments	
  (e.g.	
  gowns,	
  
disposable	
  gloves,	
  etc.)	
  when	
  providing	
  care	
  to	
  any	
  pa,ent	
  
with	
  crusted	
  scabies	
  un,l	
  successfully	
  treated	
  
•  Wash	
  hands	
  thoroughly	
  aIer	
  providing	
  care	
  to	
  any	
  pa,ent	
  
•  Isolate	
  pa,ents	
  with	
  crusted	
  scabies	
  from	
  other	
  pa,ents	
  who	
  
do	
  not	
  have	
  crusted	
  scabies;	
  consider	
  assigning	
  a	
  cohort	
  of	
  
caretakers	
  to	
  care	
  only	
  for	
  pa,ents	
  with	
  crusted	
  scabies	
  
•  Maintain	
  contact	
  precau,ons	
  un,l	
  skin	
  scrapings	
  from	
  a	
  
pa,ent	
  with	
  crusted	
  scabies	
  are	
  nega,ve	
  
•  Pa,ents	
  with	
  crusted	
  scabies	
  generally	
  must	
  be	
  treated	
  at	
  least	
  
twice,	
  a	
  week	
  apart;	
  oral	
  Ivermec,n	
  may	
  be	
  necessary	
  for	
  
successful	
  treatment.	
  
•  Limit	
  visitors	
  for	
  pa,ents	
  with	
  crusted	
  scabies;	
  visitors	
  should	
  
use	
  the	
  same	
  contact	
  precau,ons	
  and	
  protec,ve	
  clothing	
  as	
  
staff.	
  
21	
  
Home	
  Treatment	
  
•  Cool	
  and	
  soak	
  your	
  skin.	
  Soaking	
  in	
  cool	
  water	
  or	
  
applying	
  a	
  cool,	
  wet	
  washcloth	
  to	
  irritated	
  areas	
  
of	
  your	
  skin	
  may	
  minimize	
  itching.	
  
•  Apply	
  soothing	
  lo9on.	
  Calamine	
  lo,on,	
  available	
  
without	
  a	
  prescrip,on,	
  can	
  effec,vely	
  relieve	
  the	
  
pain	
  and	
  itching	
  of	
  minor	
  skin	
  irrita,ons.	
  
•  Take	
  an9histamines.	
  At	
  your	
  doctor's	
  sugges,on,	
  
you	
  may	
  find	
  that	
  over-­‐the-­‐counter	
  
an,histamines	
  relieve	
  the	
  allergic	
  symptoms	
  
caused	
  by	
  scabies.	
  
22	
  
Preven9on	
  
•  Clean	
  all	
  clothes	
  and	
  linen.	
  Use	
  hot,	
  soapy	
  water	
  
to	
  wash	
  all	
  clothing,	
  towels	
  and	
  bedding	
  you	
  used	
  
at	
  least	
  three	
  days	
  before	
  treatment.	
  Dry	
  with	
  
high	
  heat.	
  	
  
•  Starve	
  the	
  mites.	
  Consider	
  placing	
  items	
  you	
  
can't	
  wash	
  in	
  a	
  sealed	
  plas,c	
  bag	
  and	
  leaving	
  it	
  in	
  
an	
  out-­‐of-­‐the-­‐way	
  place,	
  such	
  as	
  in	
  your	
  garage,	
  
for	
  a	
  couple	
  of	
  weeks.	
  Mites	
  die	
  if	
  they	
  don't	
  eat	
  
for	
  a	
  week	
  
23	
  
Myiasis	
  
•  Invasion	
  of	
  ,ssues	
  by	
  fly	
  larvae,	
  eggs	
  hatch,	
  
burrow	
  into	
  skin	
  
•  Furuncle	
  with	
  maggots	
  in	
  the	
  center	
  
•  Cochliomyia	
  hominivorax	
  (Screw	
  worm)	
  	
  	
  MC	
  
cause	
  wound	
  myiasis	
  in	
  USA	
  
•  Phormia	
  regina	
  (Black	
  Blowfly,	
  USA)	
  
•  Dermatobia	
  hominis	
  (bojly,	
  New	
  World)	
  
•  Cordylobia	
  anthropophaga	
  (Tumbu	
  Fly,	
  Africa)	
  
24	
  
Myiasis	
  
•  Hrysomya	
  bezziana	
  is	
  found	
  in	
  Africa,	
  India,	
  and	
  
Southeast	
  Asia.	
  The	
  life	
  cycle	
  and	
  biologic	
  ac,vity	
  
of	
  C.	
  bezziana	
  is	
  similar	
  to	
  that	
  of	
  C.	
  hominivorax	
  
•  These	
  larvae	
  burrow	
  deeper	
  into	
  host	
  ,ssue,	
  only	
  
the	
  black	
  tail	
  ends	
  are	
  seen.	
  C.	
  bezziana	
  infests	
  
wounds,	
  areas	
  of	
  soI	
  skin,	
  and	
  mucous	
  
membranes	
  
•  Only	
  presen,ng	
  features	
  of	
  a	
  nasal	
  sinus	
  
infesta,on	
  may	
  be	
  a	
  swollen	
  face	
  associated	
  with	
  
headaches,	
  fever,	
  burning	
  nasal	
  pain,	
  and	
  a	
  nasal	
  
discharge	
  
25	
  
Myiasis	
  

Petruss, Wikimedia Commons

26	
  
Myiasis	
  Symptoms	
  
•  Infesta,on	
  sites	
  are	
  exposed	
  areas	
  such	
  as	
  the	
  
extremi,es,	
  back,	
  and	
  scalp	
  
•  Within	
  24	
  hours,	
  a	
  papule	
  resembling	
  an	
  insect	
  
bite	
  will	
  swell	
  into	
  a	
  boil-­‐like	
  lesion	
  ranging	
  
anywhere	
  from	
  10-­‐35	
  mm	
  in	
  diameter.	
  OIen,	
  
there	
  is	
  a	
  small	
  (2-­‐3	
  mm	
  diameter)	
  pore	
  at	
  the	
  
center	
  of	
  the	
  boil	
  which	
  allows	
  the	
  larvae	
  to	
  
breathe	
  
•  The	
  pa,ent	
  may	
  experience	
  pain,	
  and	
  some	
  have	
  
reported	
  feeling	
  the	
  larvae	
  moving	
  around	
  in	
  the	
  
,ssues.	
  	
  
27	
  
Trea9ng	
  Myiasis	
  
•  Surgical	
  removal	
  with	
  local	
  anesthesia	
  is	
  usually	
  the	
  
preferred	
  approach	
  
–  The	
  skin	
  lesion	
  is	
  locally	
  anesthe,zed	
  with	
  lidocaine	
  and	
  
excised	
  surgically	
  followed	
  by	
  primary	
  wound	
  closure	
  
–  Alterna,vely,	
  Lidocaine	
  can	
  be	
  injected	
  forcibly	
  into	
  the	
  
base	
  of	
  the	
  lesion	
  in	
  an	
  aSempt	
  to	
  create	
  enough	
  fluid	
  
pressure	
  to	
  extrude	
  the	
  larvae	
  out	
  of	
  the	
  puncture	
  
–  Treatments	
  include	
  petroleum	
  jelly,	
  liquid	
  paraffin,	
  beeswax	
  or	
  
heavy	
  oil,	
  or	
  lard	
  or	
  bacon	
  strips	
  placed	
  over	
  the	
  central	
  punctum	
  
and	
  have	
  been	
  used	
  to	
  coax	
  the	
  larva	
  to	
  emerge	
  spontaneously	
  
head-­‐first	
  over	
  the	
  course	
  of	
  several	
  hours,	
  at	
  which	
  ,me,	
  
tweezers	
  (or	
  forceps)	
  aid	
  in	
  the	
  capture.	
  

	
  
28	
  
Trea9ng	
  Myiasis	
  	
  
•  Larvicides	
  –	
  Ivermec,n	
  is	
  a	
  broad	
  spectrum	
  
an,parasi,c	
  that	
  may	
  kill	
  larvae,	
  or	
  cause	
  
them	
  to	
  migrate	
  out	
  of	
  the	
  skin	
  
•  Apply	
  topically	
  or	
  as	
  an	
  oral	
  dose	
  
•  Mineral	
  turpen,ne	
  can	
  be	
  effec,ve	
  against	
  
Chrysomya	
  larvae	
  and	
  may	
  aid	
  their	
  removal	
  
in	
  cases	
  of	
  wound	
  myiasis.	
  
•  Ethanol	
  spray	
  and	
  oil	
  of	
  betel	
  leaf	
  can	
  be	
  used	
  
topically	
  to	
  treat	
  C.	
  hominivorax	
  myiasis	
  
29	
  
Nursing	
  Interven9ons	
  
• 
• 
• 
• 
• 

No,fy	
  the	
  pa,ent	
  
Calm	
  the	
  pa,ent	
  and/or	
  staff	
  
No,fy	
  the	
  nurse	
  supervisor	
  or	
  nurse	
  manager	
  
Locate	
  the	
  policy	
  or	
  protocol	
  to	
  control	
  myiasis	
  
Use	
  standard	
  precau,ons,	
  remove	
  larvae	
  (MD	
  or	
  
NP)	
  
–  Do	
  NOT	
  smoosh	
  or	
  smash	
  
–  If	
  en,re	
  larvae	
  not	
  visible	
  apply	
  petroleum	
  jellyPlace	
  
larvae	
  in	
  specimen	
  cup,	
  label	
  with	
  pa,ent	
  name,	
  date,	
  
,me	
  and	
  send	
  to	
  lab	
  immediately	
  (within	
  24	
  hours)	
  

30	
  
Nursing	
  Interven9ons	
  
•  Place	
  larvae	
  in	
  specimen	
  
cup,	
  label	
  with	
  pa,ent	
  
name,	
  date,	
  ,me	
  and	
  
send	
  to	
  lab	
  immediately	
  
(within	
  24	
  hours)	
  
•  Clean	
  infected	
  area	
  with	
  
sterile	
  saline	
  or	
  hydrogen	
  
peroxide	
  
•  Document	
  what	
  was	
  done	
  
•  Broad	
  spectrum	
  
Ivermec,n	
  is	
  prescribed	
  
Journalist Seaman Erica Mater, Wikimedia31	
  
Commons
Preven9on	
  
•  Use	
  window	
  screens	
  and	
  mosquito	
  neong,	
  
insect	
  repellent	
  and	
  insec,cides,	
  adequate	
  
protec,ve	
  clothing,	
  cover	
  open	
  wounds	
  and	
  
change	
  dressings	
  daily	
  
•  In	
  the	
  case	
  of	
  C.	
  anthropophaga,	
  hang	
  clothes	
  
to	
  dry	
  in	
  bright	
  sunlight	
  and/or	
  iron	
  them	
  (the	
  
heat	
  destroys	
  both	
  the	
  eggs	
  and	
  larvae)	
  
•  Improve	
  hygiene	
  and	
  sanita,on	
  (e.g.	
  remove	
  
rubbish	
  from	
  around	
  living	
  areas)	
  
32	
  
Risk	
  Factors	
  
• 
• 
• 
• 
• 
• 

Poor	
  hygiene	
  
Open	
  wounds	
  
Immunocompromised	
  
Warm	
  climate	
  
Food	
  containers	
  leI	
  uncovered	
  
Overflowing	
  garbage	
  bins	
  

33	
  
Case	
  Study	
  
•  65	
  –	
  year	
  old	
  woman	
  with	
  hypertension	
  and	
  
diabetes	
  presents	
  to	
  the	
  emergency	
  room	
  
with	
  an	
  ulcer	
  on	
  her	
  right	
  leg.	
  Necro,c	
  ,ssue	
  
and	
  tunneling	
  are	
  present	
  in	
  the	
  wound	
  bed.	
  
“Worms”	
  were	
  observed	
  by	
  the	
  nursing	
  
assistant.	
  What	
  is	
  the	
  possible	
  clinical	
  
presenta,on?	
  

34	
  
Case	
  Study	
  
•  Answer:	
  	
  Wound	
  Myiasis	
  

35	
  

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Ghana Skin Infection Guide

  • 1. Project: Ghana Emergency Medicine Collaborative Document Title: Skin Infections Author(s): Katherine Perry (University of Michigan), RN BSN 2012 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike-3.0 License: http://creativecommons.org/licenses/by-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. These lectures have been modified in the process of making a publicly shareable version. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/privacy-and-terms-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers. 1  
  • 2. Attribution Key for more information see: http://open.umich.edu/wiki/AttributionPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (17 USC § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (17 USC § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. 2   To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  • 3. Lice   •  Lice  are  parasi,c  insects  that  can  be  found  on   people's  heads,  and  bodies   •  Human  lice  survive  by  feeding  on  human  blood   •  Lice  found  on  each  area  of  the  body  are  different   from  each  other.  The  three  types  of  lice  that  live   on  humans  are:   –  Pediculus  humanus  capi/s  (head  louse)   –  Pediculus  humanus  corporis  (body  louse,  clothes   louse)  and   –  Pthirus  pubis  ("crab"  louse,  pubic  louse)   3  
  • 4. Lice   •  Lice  infesta,ons  (pediculosis  and  pthiriasis)  are  spread  most   commonly  by  close  person-­‐to-­‐person  contact   •  Found  mainly  in  children  who  go  to  school,  especially  just  aIer  the   holidays   •  Are  found  in  both  clean  and  dirty  hair   •  Feed  on  human  blood   •  Do  not  always  cause  itching   •  Cannot  be  killed  by  regular  shampoos  but  can  be  eliminated  by   using  special  head  lice  medica,on   •  Do  not  transmit  diseases   •  Do  not  live  on  pets   4  
  • 5. Symptoms   •  Itching  is  hallmark  symptom  caused  by  allergic   reac,on   •  Lice  bite  the  skin  and  feed  on  person’s  skin   which  leads  to  allergic  reac,on  and  itching   5  
  • 6. Head  Lice   •  Head  lice  and  their  eggs  (nits)  can  be  seen  on  hair,   nape  of  the  neck  and  behind  ears     •  They  can  vary  in  color  from  white  to  brown  to  dark   grey     •  Eggs  are  ,ny  round    or  oval  that  are  ,ghtly  aSached   to  the  hair  near  scalp   6  
  • 7. Head  Lice   Wellcome Images, Wellcome Images 7  
  • 8. Pubic  Lice   •  Itching  around  the  genitals  as  well  as  the  anus,   armpits,  eyelashes,  and  other  body  areas  with   hair   •   Pubic  lice  bites  may  cause  small,  flat,  blue-­‐ gray  marks  (maculae  cerulea)  that  look  like   bruises  on  torso,  thighs  or  upper  arm     •  Pubic  lice  that  infect  eyelashes  &  eyelids  may   cause  irrita,on  and  crus,ng  in  those  areas     •  Pubic  lice  tends  to  spread  by  sexual  contact   8  
  • 10. Body  Lice   •  Itchy  sores  usually  develop  in  the  armpits,   around  the  waist,  and  along  the  trunk  where   seams  of  clothes  press  against  the  skin   •  The  lice  and  eggs  are  generally  not  seen  on   the  skin  but  may  be  found  in  the  seams  of  the   person's  clothing.   10  
  • 11. Treatment   •  Check  for  live  lice  and  nits   •  Work  in  strong  light  and  sec,on  the  hair.  Use  a   fine-­‐tooth  comb  (a  pet  flea  comb  works  well)  to   find  the  insects  and  to  comb  them  out  if  possible;   or  remove  them  using  tweezers   •  Adult  lice  are  reddish-­‐brown;  nits  are  white  or   clear  and  adhere  to  the  hair  shaI.  They  do  not   jump  or  fly   •  Medicated  shampoo,    cream  rinse,  or  lo,on  to   kill  the  lice   11  
  • 12. Treatment   •  Medicated  lice  treatments  usually  kill  the  lice  and  nits,  but  it  may  take  a  few   days  for  the  itching  to  stop.  For  very  resistant  lice,  an  oral  medica,on  might   be  prescribed.   •  Follow  the  direc,ons  exactly  because  these  products  are  insec,cides   •  Applying  too  much  medica,on  —  or  using  it  too  frequently  —  can  increase   the  risk  of  causing  harm.  Follow  the  direc,ons  on  the  product  label  to  ensure   that  the  treatment  works  properly.   12  
  • 13. Treatment     •  Treatment  may  be  unsuccessful  if  the   medica,on  is  not  used  correctly  or  if  the  lice   are  resistant  to  it   •   AIer  treatment,  your  doctor  may  suggest   combing  out  the  nits  with  a  fine-­‐tooth  comb   and  also  may  recommend  repea,ng   treatment  in  7  to  10  days  to  kill  any  newly   hatched  nits.   Priwo, Wikimedia13   Commons
  • 14. Treatment   •  Check  everyone  in  the  household.  Lice  are  very   contagious   •  Wash  all  bedding,  recently  used  towels  and   recently  worn  clothing  in  hot  water,  and  dry   them  in  a  hot  dryer   •   Soak  all  combs  and  brushes  in  hot  water  for  at   least  10  minutes   •  Treat  eyelashes  and  eyebrows  with  a  thick  layer   of  petroleum  jelly.  Apply  twice  a  day  for  8  days.   Never  use  any  chemical  treatment  on  eyelashes   or  eyebrows   14  
  • 15. Scabies   •  Easily  spread  skin  disease  caused  by  a  very   small  species  of  mite   Kalumet, Wikimedia Commons 15  
  • 16. Scabies   •  Eight-­‐legged  mite  causes  scabies  in  humans  is  microscopic   •  The  female  mite  burrows  just  beneath  your  skin  and   produces  a  tunnel  in  which  it  deposits  eggs   •  Eggs  mature  in  21  days,  and  the  new  mites  work  their  way   to  the  surface  of  your  skin,  where  they  mature  and  can   spread  to  other  areas  of  your  skin  or  to  the  skin  of  other   people   •  Close  physical  contact  and,  less  oIen,  sharing  clothing  or   bedding  with  an  infected  person  can  spread  the  mites.   •  Dogs,  cats  and  humans  all  are  affected  by  their  own  dis,nct   species  of  mite.  Each  species  of  mite  prefers  one  specific   type  of  host  and  doesn't  live  long  away  from  that  preferred   host.   16  
  • 17. Scabies  Symptoms   •  Mites  that  cause  scabies  burrow  into  the  skin  and  deposit   their  eggs,  forming  a  burrow  that  looks  like  a  pencil  mark   •  Eggs  mature  in  21  days   •  Itching,  Rashes,  Sores  (abrasions)  on  the  skin  from   scratching  and  digging   •  Thin,    pencil-­‐mark  lines  on  the  skin   •  Mites  may  be  more  widespread  on  a  baby's  skin,  causing   pimples  over  the  trunk,  or  small  blisters  over  palms  or   soles   •  In  young  children,  the  head,  neck,  shoulders,  palms,  and   soles  are  involved.   •  In  older  children  and  adults,  the  hands,  wrists,  genitals,   and  abdomen  are  involved.   17  
  • 18. Complica9ons  of  Scabies   •  A  more  severe  form  of  scabies,  called  crusted   scabies,  may  affect  certain  high-­‐risk  groups,   including:   –  People  with  chronic  health  condi,ons  that  weaken  the   immune  system,  such  as  HIV  or  chronic  leukemia   –  People  who  are  very  ill,  such  as  people  in  hospitals  or   nursing  facili,es   –  Crusted  scabies  tends  to  be  crusty  and  scaly,  and  covers   large  areas  of  the  body.  It's  very  contagious  and  can  be   hard  to  treat   18  
  • 19. Scabies  Diagnosis   •  The  microscopic  examina,on  can  determine   the  presence  of  mites  or  their  eggs   Michael Geary, Wikimedia Commons 19  
  • 20. Treatment   •  Permethrin  5  percent  (Elimite)  -­‐  twice,  with  a  week  or  so   between  each  applica,on.  Permethrin  is  generally   considered  safe  for  children  and  adults  of  all  ages,   including  women  who  are  pregnant  or  nursing.   •  Lindane  -­‐  usually  applied  in  two  treatments,  spaced  about   a  week  apart.  This  medica,on  isn't  safe  for  children   younger  than  age  2  years,  women  who  are  pregnant  or   nursing,  or  people  with  weakened  immune  systems.   •  Crotamiton  (Eurax)  -­‐  nonchemical  medica,on  is  applied   once  a  day  for  two  to  five  days   •  Although  these  medica,ons  kill  the  mites  promptly,  you   may  find  that  the  itching  doesn't  stop  en,rely  for  several   weeks   20  
  • 21. Isola9on  Precau9ons   •  Contact  precau,ons  with  protec,ve  garments  (e.g.  gowns,   disposable  gloves,  etc.)  when  providing  care  to  any  pa,ent   with  crusted  scabies  un,l  successfully  treated   •  Wash  hands  thoroughly  aIer  providing  care  to  any  pa,ent   •  Isolate  pa,ents  with  crusted  scabies  from  other  pa,ents  who   do  not  have  crusted  scabies;  consider  assigning  a  cohort  of   caretakers  to  care  only  for  pa,ents  with  crusted  scabies   •  Maintain  contact  precau,ons  un,l  skin  scrapings  from  a   pa,ent  with  crusted  scabies  are  nega,ve   •  Pa,ents  with  crusted  scabies  generally  must  be  treated  at  least   twice,  a  week  apart;  oral  Ivermec,n  may  be  necessary  for   successful  treatment.   •  Limit  visitors  for  pa,ents  with  crusted  scabies;  visitors  should   use  the  same  contact  precau,ons  and  protec,ve  clothing  as   staff.   21  
  • 22. Home  Treatment   •  Cool  and  soak  your  skin.  Soaking  in  cool  water  or   applying  a  cool,  wet  washcloth  to  irritated  areas   of  your  skin  may  minimize  itching.   •  Apply  soothing  lo9on.  Calamine  lo,on,  available   without  a  prescrip,on,  can  effec,vely  relieve  the   pain  and  itching  of  minor  skin  irrita,ons.   •  Take  an9histamines.  At  your  doctor's  sugges,on,   you  may  find  that  over-­‐the-­‐counter   an,histamines  relieve  the  allergic  symptoms   caused  by  scabies.   22  
  • 23. Preven9on   •  Clean  all  clothes  and  linen.  Use  hot,  soapy  water   to  wash  all  clothing,  towels  and  bedding  you  used   at  least  three  days  before  treatment.  Dry  with   high  heat.     •  Starve  the  mites.  Consider  placing  items  you   can't  wash  in  a  sealed  plas,c  bag  and  leaving  it  in   an  out-­‐of-­‐the-­‐way  place,  such  as  in  your  garage,   for  a  couple  of  weeks.  Mites  die  if  they  don't  eat   for  a  week   23  
  • 24. Myiasis   •  Invasion  of  ,ssues  by  fly  larvae,  eggs  hatch,   burrow  into  skin   •  Furuncle  with  maggots  in  the  center   •  Cochliomyia  hominivorax  (Screw  worm)      MC   cause  wound  myiasis  in  USA   •  Phormia  regina  (Black  Blowfly,  USA)   •  Dermatobia  hominis  (bojly,  New  World)   •  Cordylobia  anthropophaga  (Tumbu  Fly,  Africa)   24  
  • 25. Myiasis   •  Hrysomya  bezziana  is  found  in  Africa,  India,  and   Southeast  Asia.  The  life  cycle  and  biologic  ac,vity   of  C.  bezziana  is  similar  to  that  of  C.  hominivorax   •  These  larvae  burrow  deeper  into  host  ,ssue,  only   the  black  tail  ends  are  seen.  C.  bezziana  infests   wounds,  areas  of  soI  skin,  and  mucous   membranes   •  Only  presen,ng  features  of  a  nasal  sinus   infesta,on  may  be  a  swollen  face  associated  with   headaches,  fever,  burning  nasal  pain,  and  a  nasal   discharge   25  
  • 27. Myiasis  Symptoms   •  Infesta,on  sites  are  exposed  areas  such  as  the   extremi,es,  back,  and  scalp   •  Within  24  hours,  a  papule  resembling  an  insect   bite  will  swell  into  a  boil-­‐like  lesion  ranging   anywhere  from  10-­‐35  mm  in  diameter.  OIen,   there  is  a  small  (2-­‐3  mm  diameter)  pore  at  the   center  of  the  boil  which  allows  the  larvae  to   breathe   •  The  pa,ent  may  experience  pain,  and  some  have   reported  feeling  the  larvae  moving  around  in  the   ,ssues.     27  
  • 28. Trea9ng  Myiasis   •  Surgical  removal  with  local  anesthesia  is  usually  the   preferred  approach   –  The  skin  lesion  is  locally  anesthe,zed  with  lidocaine  and   excised  surgically  followed  by  primary  wound  closure   –  Alterna,vely,  Lidocaine  can  be  injected  forcibly  into  the   base  of  the  lesion  in  an  aSempt  to  create  enough  fluid   pressure  to  extrude  the  larvae  out  of  the  puncture   –  Treatments  include  petroleum  jelly,  liquid  paraffin,  beeswax  or   heavy  oil,  or  lard  or  bacon  strips  placed  over  the  central  punctum   and  have  been  used  to  coax  the  larva  to  emerge  spontaneously   head-­‐first  over  the  course  of  several  hours,  at  which  ,me,   tweezers  (or  forceps)  aid  in  the  capture.     28  
  • 29. Trea9ng  Myiasis     •  Larvicides  –  Ivermec,n  is  a  broad  spectrum   an,parasi,c  that  may  kill  larvae,  or  cause   them  to  migrate  out  of  the  skin   •  Apply  topically  or  as  an  oral  dose   •  Mineral  turpen,ne  can  be  effec,ve  against   Chrysomya  larvae  and  may  aid  their  removal   in  cases  of  wound  myiasis.   •  Ethanol  spray  and  oil  of  betel  leaf  can  be  used   topically  to  treat  C.  hominivorax  myiasis   29  
  • 30. Nursing  Interven9ons   •  •  •  •  •  No,fy  the  pa,ent   Calm  the  pa,ent  and/or  staff   No,fy  the  nurse  supervisor  or  nurse  manager   Locate  the  policy  or  protocol  to  control  myiasis   Use  standard  precau,ons,  remove  larvae  (MD  or   NP)   –  Do  NOT  smoosh  or  smash   –  If  en,re  larvae  not  visible  apply  petroleum  jellyPlace   larvae  in  specimen  cup,  label  with  pa,ent  name,  date,   ,me  and  send  to  lab  immediately  (within  24  hours)   30  
  • 31. Nursing  Interven9ons   •  Place  larvae  in  specimen   cup,  label  with  pa,ent   name,  date,  ,me  and   send  to  lab  immediately   (within  24  hours)   •  Clean  infected  area  with   sterile  saline  or  hydrogen   peroxide   •  Document  what  was  done   •  Broad  spectrum   Ivermec,n  is  prescribed   Journalist Seaman Erica Mater, Wikimedia31   Commons
  • 32. Preven9on   •  Use  window  screens  and  mosquito  neong,   insect  repellent  and  insec,cides,  adequate   protec,ve  clothing,  cover  open  wounds  and   change  dressings  daily   •  In  the  case  of  C.  anthropophaga,  hang  clothes   to  dry  in  bright  sunlight  and/or  iron  them  (the   heat  destroys  both  the  eggs  and  larvae)   •  Improve  hygiene  and  sanita,on  (e.g.  remove   rubbish  from  around  living  areas)   32  
  • 33. Risk  Factors   •  •  •  •  •  •  Poor  hygiene   Open  wounds   Immunocompromised   Warm  climate   Food  containers  leI  uncovered   Overflowing  garbage  bins   33  
  • 34. Case  Study   •  65  –  year  old  woman  with  hypertension  and   diabetes  presents  to  the  emergency  room   with  an  ulcer  on  her  right  leg.  Necro,c  ,ssue   and  tunneling  are  present  in  the  wound  bed.   “Worms”  were  observed  by  the  nursing   assistant.  What  is  the  possible  clinical   presenta,on?   34  
  • 35. Case  Study   •  Answer:    Wound  Myiasis   35