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ERAS! 
THE ROLE OF ANAESTHESIOLOGIST 
DR.P.C.VIJAYAKUMAR 
PRESIDENT-IAPEN- TAMILNADU CHAPTER 
SOORIYA HOSPITAL 
CHENNAI,TAMILNADU,INDIA.
TRADITIONAL 
PERIOPERATIVE CARE
•1.STARVE!! 
IATROGENIC STARVATION
2.STRESS!! 
INCISION,PAIN,IMMOBILIZATION
3.DROWN! 
DROWNING IN THE I.V.FLUIDS!
CHANGE THE TRADITION !
Enhanced recovery after surgery 
Surgery Multi-modal intervention 
Traditional care 
Days Weeks
EVIDENCE TO SAY NO TO 
STARVATION!
Mendelson's syndrome 
2006 saw the 60th anniversary of the publication of New York obstetrician Curtis 
Lester Mendelson's classic paper, ‘The aspiration of stomach contents into the lungs 
during obstetric anesthesia’. 
Mendelson went on to show that acid was responsible for this asthma-like 
syndrome. He instilled into the respiratory tracts of rabbits a variety of substances 
including 0.1N hydrochloric acid and vomitus (both untreated and neutralized) from 
pregnant women. 
He concluded that gastric retention of solid and liquid material is prolonged during 
labour, and that aspiration of vomitus into the lungs can occur while laryngeal 
reflexes are abolished. 
‘Respiratory failure secondary to aspiration pneumonitis during anaesthesia’ became 
synonymous with Mendelson's syndrome, and its prevention a cornerstone of 
anaesthetic practice.
Key points 
Residual gastric volume (RGV) and pH (two surrogate end-points of aspiration risk) 
are determined by oral intake, gastric secretion and gastric emptying. A 2 h fasting 
interval (vs. midnight) for fluids neither increases RGV nor decreases pH. 
Gastric emptying of liquids is an exponential process. The half-time for water is 
about 10 min. It is wrong to regard the stomach as either ‘empty’ or ‘full’, and 
induction of anaesthesia ‘safe’ or ‘unsafe’. 
Current accepted fasting intervals for elective cases are 2 h for water and clear fluids, 
4 h for breast milk, and 6 h for food (including milky drinks). ‘Nil by mouth from 
midnight’ has no place in modern perioperative practice. 
Gastric emptying is impaired by trauma, labour and opioid analgesia. Fasting 
intervals assume limited importance compared with other aspects of the 
anaesthesia regimen (e.g. choice of airway management) in the prevention of 
aspiration. 
The ‘top 3’ risk factors for aspiration are emergency surgery, light 
anaesthesia/unexpected response to stimulation and upper/lower gastrointestinal 
pathology.
CHO LOADING 
What is it? 
• 100G ;12.5% ;CHO 
PREVIOUS DAY NIGHT 
• 50G ;12.5% ;CHO 2 HOURS 
BEFORE SURGERY 
• CHO MUST BE COMPLEX 
MALTODEXTRINS AND NOT 
THE PLAIN GLUCOSE!!! 
• NEED A COMMERSIAL FEED 
FOR THIS PURPOSE! 
Advantages 
• Gives satisfaction 
• Decreases stress 
• Decrease insulin resistance 
• No increase in GRV 
• No increase in aspiration
• CAN HAVE NORMAL ORAL DIET 2 HOURS 
AFTER REGIONAL AND 4 HOURS AFTER 
GENERAL ANAESTHESIA 
• DON’T EVER RESIST THE NATURAL APPETITE!
SAY NO TO PREMEDICATION 
• ADMISSION ON THE DAY OF 
SURGERY 
• NO NEED TO PREMEDICATE 
• SEDATIVES DELAYS RECOVERY 
• NO ROLE FOR PROPHYLACTIC 
ANTIEMETICS 
• GASTRIC ACID SUPPRESSION 
DELAYS APPETITE 
• GLYCO TAKES OUT THE TASTE 
/DYSPHAGIA 
PREMED 
• SEDATIVE 
DIAZEPAM 
• H2 BLOCKER/PROTON 
INHIBITORS 
RANITIDINE/OMEPERAZOLE 
• ANTISIALOGOUGE 
ATROPINE/GLYCOPYRROLATE
PONV-PREVENTION 
• PREOP RISK FACTORS 
MILD/MODERATE/SEVERE 
YOUNGER/FEMALE/OBESE/ANXIETY/MOTION 
SICKNESS/PREVIOUS PONV 
• TIVA INSTEAD OF GA IN HIGH RISK 
• AVOID NARCOTICS/VOLATILES/N2O/REVERSAL 
• LIBERAL ANTIEMETICS 
MULTIMODAL 
STEROIDS/5HT 
ANTAGONIST/METACLOPROMIDE/DOMPERIDONE
PAIN RELIEF! 
• REGIONAL ANALGESIA 
MIDTHORASIC-T8/T9; EPIDURAL 
LUMBAR EPIDURAL 
TAB-TRANSVERSUS ABDOMINIS BLOCK 
• ONLY LA ; HIGH VOLUME/LOW CONCENTRATION 
• NO NARCOTICS ;PREFERABLY SHORT ACTING FENTANYL; 
NAUSEA/ILEUS/IMMOBILITY 
• BUT CLONIDINE/DEXMED IN RA 
• GENEROUS USE OF NSAIDS 
PARENTERAL PARACETAMOL 
NSAID SUPPOSITORIES
Why epidural analgesia ?
EPIDURAL MANAGEMENT 
• IT ATTENEUATES THE STRESS RESPONSE (TETRAD OF 
ANAESTHESIA) OF SURGERY/DECREASES CATACHOLAMINES 
• EPIDURAL ANALGESIA IN LAPAROSCOPIC SURGERIES???? 
• MANAGE HYPOTENTION WITH VASOPRESSORS 
• DON’T INFUSE MORE VASOPRESSORS 
• USE LESS FLUID CHALLENGES 
• AVOID LIMB PARESIS 
• BALANCE ANALGESIA AND HYPOTENTION
INTRA-OP HYPOTHERMIA 
HYPOTHERMIA PREVENTION 
• TEMPERATURE 
MONITORING 
• HYPOTHERMIA MORE 
COMMON WITH REGIONAL 
ANAESTHESIA 
• O.T ROOM TEMPERATURE 
• EXTERNAL WARMER 
• FLUID WARMER 
ILL EFFECTS OF HYPOTHERMIA 
• INFECTION 
• POST OP SHIVERING/STRESS 
• BLEEDING 
• MI 
• ARRYTHMIA
EARLY MOBILIZATION 
• WALKING EPIDURAL 
• SEGMENTAL EPIDURAL WITH PRESERVED 
BLADDER SENSATION 
• NO SEDATIVES 
• NO NARCOTICS
HIGH INSPIRED OXYGEN 
80%-BAG&MASK 
• OXYGEN IS REQUIRED BY IMMUNE CELLS TO 
PRODUCE FREE RADICALS-A DEFENCE AGAIST 
PATHOGENS 
• NEED FOR COLLAGEN SYNTHESIS / 
ANGIOGENESIS 
• IMPROVES ANASTAMOTIC HEALING 
• DECREASE SURGICAL SITE INFECTIONS 
• REDUCE PONV
NO DROWNING IN SURGERY!!
GOAL DIRECTED INTRAOP FLUID 
THERAPY 
• EXCESS FLUIDS DELAYS GUT FUNCTION/CARDIAC 
MORBIDITY 
• LiDCO/PICCO DEVICES/OESOPHAGEAL ECHO 
• CO/SV/TLW ARE THE GOAL PARAMETERS 
• MINIMAL GOALS-UO/MAP/CVP 
• POST OP FLUIDS NOT MORE THAN 2.5 L/DAY
RESUSCITATION ELECTIVE SURGERY 
WET IS BEST BALANCED IS 
BETTER
MAINTAIN I/O CHART 
AVOID POSITIVE BALANCE
= 
POISON
The ability of the patient to get rid of the accumulated sodium is 
greatly curtailed in the postop period! 
9g Sodium Chloride = 
36 Bags of Chips, 
or 1L Bag of Saline
THE VERDICT ON SALINE 
Compared with balanced crystalloids, saline use is 
associated with: 
• Increased mortality1 
• Hyperchloremic acidosis1,2,3,4 
• Adverse effects on the kidney1,2 
• Increased morbidity1 
• Increased resource consumption1 
• DELAYED GUT FUNCTION-PARALYTIC ILEUS 
The future of IV Fluid Management: Balanced Crystalloids 
1. Shaw AD, et al., Ann Surg. 2012 May; 255(5):821-9 2. Chowdhury AH et al. Ann Surgery 2012 ;256(1):18-24 3: McFarlane C. & Lee A . Anaesthesia 1994;49:779- 
81.4: Hadimioglu N. et al. Anesth Analg. 2008;107:264-9
HOW DO I LIMIT IV 
FLUIDS/SODIUM? 
TAKE THE DRIP 
DOWN ON THE 
FIRST POST-OP DAY
LET US SEE WHEATHER THIS FIRE 
WORKS! 
T 
THANK YOU!!

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ERAS! THE ROLE OF ANAESTHESIOLOGIST

  • 1. ERAS! THE ROLE OF ANAESTHESIOLOGIST DR.P.C.VIJAYAKUMAR PRESIDENT-IAPEN- TAMILNADU CHAPTER SOORIYA HOSPITAL CHENNAI,TAMILNADU,INDIA.
  • 5. 3.DROWN! DROWNING IN THE I.V.FLUIDS!
  • 7. Enhanced recovery after surgery Surgery Multi-modal intervention Traditional care Days Weeks
  • 8. EVIDENCE TO SAY NO TO STARVATION!
  • 9. Mendelson's syndrome 2006 saw the 60th anniversary of the publication of New York obstetrician Curtis Lester Mendelson's classic paper, ‘The aspiration of stomach contents into the lungs during obstetric anesthesia’. Mendelson went on to show that acid was responsible for this asthma-like syndrome. He instilled into the respiratory tracts of rabbits a variety of substances including 0.1N hydrochloric acid and vomitus (both untreated and neutralized) from pregnant women. He concluded that gastric retention of solid and liquid material is prolonged during labour, and that aspiration of vomitus into the lungs can occur while laryngeal reflexes are abolished. ‘Respiratory failure secondary to aspiration pneumonitis during anaesthesia’ became synonymous with Mendelson's syndrome, and its prevention a cornerstone of anaesthetic practice.
  • 10.
  • 11. Key points Residual gastric volume (RGV) and pH (two surrogate end-points of aspiration risk) are determined by oral intake, gastric secretion and gastric emptying. A 2 h fasting interval (vs. midnight) for fluids neither increases RGV nor decreases pH. Gastric emptying of liquids is an exponential process. The half-time for water is about 10 min. It is wrong to regard the stomach as either ‘empty’ or ‘full’, and induction of anaesthesia ‘safe’ or ‘unsafe’. Current accepted fasting intervals for elective cases are 2 h for water and clear fluids, 4 h for breast milk, and 6 h for food (including milky drinks). ‘Nil by mouth from midnight’ has no place in modern perioperative practice. Gastric emptying is impaired by trauma, labour and opioid analgesia. Fasting intervals assume limited importance compared with other aspects of the anaesthesia regimen (e.g. choice of airway management) in the prevention of aspiration. The ‘top 3’ risk factors for aspiration are emergency surgery, light anaesthesia/unexpected response to stimulation and upper/lower gastrointestinal pathology.
  • 12. CHO LOADING What is it? • 100G ;12.5% ;CHO PREVIOUS DAY NIGHT • 50G ;12.5% ;CHO 2 HOURS BEFORE SURGERY • CHO MUST BE COMPLEX MALTODEXTRINS AND NOT THE PLAIN GLUCOSE!!! • NEED A COMMERSIAL FEED FOR THIS PURPOSE! Advantages • Gives satisfaction • Decreases stress • Decrease insulin resistance • No increase in GRV • No increase in aspiration
  • 13. • CAN HAVE NORMAL ORAL DIET 2 HOURS AFTER REGIONAL AND 4 HOURS AFTER GENERAL ANAESTHESIA • DON’T EVER RESIST THE NATURAL APPETITE!
  • 14. SAY NO TO PREMEDICATION • ADMISSION ON THE DAY OF SURGERY • NO NEED TO PREMEDICATE • SEDATIVES DELAYS RECOVERY • NO ROLE FOR PROPHYLACTIC ANTIEMETICS • GASTRIC ACID SUPPRESSION DELAYS APPETITE • GLYCO TAKES OUT THE TASTE /DYSPHAGIA PREMED • SEDATIVE DIAZEPAM • H2 BLOCKER/PROTON INHIBITORS RANITIDINE/OMEPERAZOLE • ANTISIALOGOUGE ATROPINE/GLYCOPYRROLATE
  • 15. PONV-PREVENTION • PREOP RISK FACTORS MILD/MODERATE/SEVERE YOUNGER/FEMALE/OBESE/ANXIETY/MOTION SICKNESS/PREVIOUS PONV • TIVA INSTEAD OF GA IN HIGH RISK • AVOID NARCOTICS/VOLATILES/N2O/REVERSAL • LIBERAL ANTIEMETICS MULTIMODAL STEROIDS/5HT ANTAGONIST/METACLOPROMIDE/DOMPERIDONE
  • 16.
  • 17. PAIN RELIEF! • REGIONAL ANALGESIA MIDTHORASIC-T8/T9; EPIDURAL LUMBAR EPIDURAL TAB-TRANSVERSUS ABDOMINIS BLOCK • ONLY LA ; HIGH VOLUME/LOW CONCENTRATION • NO NARCOTICS ;PREFERABLY SHORT ACTING FENTANYL; NAUSEA/ILEUS/IMMOBILITY • BUT CLONIDINE/DEXMED IN RA • GENEROUS USE OF NSAIDS PARENTERAL PARACETAMOL NSAID SUPPOSITORIES
  • 19. EPIDURAL MANAGEMENT • IT ATTENEUATES THE STRESS RESPONSE (TETRAD OF ANAESTHESIA) OF SURGERY/DECREASES CATACHOLAMINES • EPIDURAL ANALGESIA IN LAPAROSCOPIC SURGERIES???? • MANAGE HYPOTENTION WITH VASOPRESSORS • DON’T INFUSE MORE VASOPRESSORS • USE LESS FLUID CHALLENGES • AVOID LIMB PARESIS • BALANCE ANALGESIA AND HYPOTENTION
  • 20. INTRA-OP HYPOTHERMIA HYPOTHERMIA PREVENTION • TEMPERATURE MONITORING • HYPOTHERMIA MORE COMMON WITH REGIONAL ANAESTHESIA • O.T ROOM TEMPERATURE • EXTERNAL WARMER • FLUID WARMER ILL EFFECTS OF HYPOTHERMIA • INFECTION • POST OP SHIVERING/STRESS • BLEEDING • MI • ARRYTHMIA
  • 21.
  • 22. EARLY MOBILIZATION • WALKING EPIDURAL • SEGMENTAL EPIDURAL WITH PRESERVED BLADDER SENSATION • NO SEDATIVES • NO NARCOTICS
  • 23. HIGH INSPIRED OXYGEN 80%-BAG&MASK • OXYGEN IS REQUIRED BY IMMUNE CELLS TO PRODUCE FREE RADICALS-A DEFENCE AGAIST PATHOGENS • NEED FOR COLLAGEN SYNTHESIS / ANGIOGENESIS • IMPROVES ANASTAMOTIC HEALING • DECREASE SURGICAL SITE INFECTIONS • REDUCE PONV
  • 24. NO DROWNING IN SURGERY!!
  • 25. GOAL DIRECTED INTRAOP FLUID THERAPY • EXCESS FLUIDS DELAYS GUT FUNCTION/CARDIAC MORBIDITY • LiDCO/PICCO DEVICES/OESOPHAGEAL ECHO • CO/SV/TLW ARE THE GOAL PARAMETERS • MINIMAL GOALS-UO/MAP/CVP • POST OP FLUIDS NOT MORE THAN 2.5 L/DAY
  • 26. RESUSCITATION ELECTIVE SURGERY WET IS BEST BALANCED IS BETTER
  • 27. MAINTAIN I/O CHART AVOID POSITIVE BALANCE
  • 29. The ability of the patient to get rid of the accumulated sodium is greatly curtailed in the postop period! 9g Sodium Chloride = 36 Bags of Chips, or 1L Bag of Saline
  • 30. THE VERDICT ON SALINE Compared with balanced crystalloids, saline use is associated with: • Increased mortality1 • Hyperchloremic acidosis1,2,3,4 • Adverse effects on the kidney1,2 • Increased morbidity1 • Increased resource consumption1 • DELAYED GUT FUNCTION-PARALYTIC ILEUS The future of IV Fluid Management: Balanced Crystalloids 1. Shaw AD, et al., Ann Surg. 2012 May; 255(5):821-9 2. Chowdhury AH et al. Ann Surgery 2012 ;256(1):18-24 3: McFarlane C. & Lee A . Anaesthesia 1994;49:779- 81.4: Hadimioglu N. et al. Anesth Analg. 2008;107:264-9
  • 31. HOW DO I LIMIT IV FLUIDS/SODIUM? TAKE THE DRIP DOWN ON THE FIRST POST-OP DAY
  • 32. LET US SEE WHEATHER THIS FIRE WORKS! T THANK YOU!!