24. RECOMMENED DOSES OF MEDICATIONS FOR ACUTE ASTHMA(CONT.) Drug Dose L-epinephrine (1:1000) or terbutaline (1.0 mg/mg) 0.01ml/kg/dose SC or IM (max 0.4 ml) May be repeated every 10-15 min IV terbutaline 10 µg/kg bolus over 10 min,then 0.1-0.3 µg/kg/min infusion Every 30 min,may increase infusion by 0.3 µg/kg/min to a max of 5 µg/kg/min Prednisolone 2 mg/kg (max 60mg), in ED 1 mg/kg/dose bid, home therapy Dexamethasone 0.6mg/kg PO, 2 dose 24 hrs apart IV methylprednisolone 1-2 mg/kg (max 125 mg) IV magnesium sulfate 50-75 mg/kg over 20 min(max 2.5g)
29. Increased mucus secretion, cell death, and sloughing, a peribronchiolar lymphocytic infiltrate and submucosal edema Combination of debris&edema produces critical narrowing & obstruction of small airways .
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31. SUGGEST BRONCHIOLITIS ASSESSMENT TOOL Mild Moderate Severe Feeding Normal Less Poor SaO2 in room air ≥ 95 % 92 -94 % < 92 % Respiratory rate(/min) < 60 60 - 70 > 70 Retraction None/ minimal Intercostal Substernal Accessory muscle use None None Neck or abdominal Wheeze None/minimal Moderate expiratory Severe inspiratory/expiratory, audible without stethoscope Air exchange Good, equal breath sound Localized decrease breath sound Multiple area of decrease breath sound
32. ED MANAGEMENT OF BRONCHIOLITIS Improved Not Improved Improved Not Improved
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41. HTTP://EMEDICINE.MEDSCAPE.COM/ARTICLE/800428-TREATMENT PEDIATRIC BRONCHIOLITIS: DIFFERENTIAL DIAGNOSES & WORKUP AUTHOR: MARK LOUDEN, MD, FACEP, ASSISTANT MEDICAL DIRECTOR, EMERGENCY DEPARTMENT, DUKE RALEIGH HOSPITAL CONTRIBUTOR INFORMATION AND DISCLOSURES UPDATED: DEC 27, 2010
Infection of bronchiolar respiratory and ciliated epithelial cells produces increased mucus secretion, cell death, and sloughing, followed by a peribronchiolar lymphocytic infiltrate and submucosal edema. The combination of debris and edema produces critical narrowing and obstruction of small airways.