As per the report “Global IV Iron Market: 2014 Edition” by Koncept Analytics. For more mail me: vikas@konceptanalytics.com

1. Global IV Iron Drugs Market
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2014
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2. Executive Summary
Iron is one of the most important nutritional requirements of the human body as it plays an important role in the managing many vital
biological processes. These biological processes encompass synthesis of heme which forms the basis of hemoglobin; the oxygen-
carrying protein of the blood; the formation of myoglobin, energy metabolism, neurotransmitter production, the formation of collagen
and immune system function apart from others. An individual suffering from iron deficiency can maintain the requisite level of iron
mainly through two types of supplements: oral iron supplements and intravenous iron supplements (IV). Treatment with oral iron
supplements is simple, inexpensive and a relatively effective way of treating iron deficiency conditions; however, in many iron deficient
conditions, oral iron is a less than the ideal treatment.
Intravenous (IV) treatment, in a broad sense, covers all the types of medications delivered intravenously, i.e. directly into the vein,
through intravenous (IV) drip. Compared to the other routes of infusing medications, the intravenous route is the fastest way to deliver
fluids and medications throughout the body. Also, this method ensures 100% bioavailability, which means that the chemicals delivered
are fully absorbed by the body. The first iron product for intravenous use was high-molecular-weight iron dextran. Some of the major
areas of IV iron application include gynecology, gastroenterology, oncology and surgeries. Hemoglobin, Ferritin, Transferrin, and
Hepcidin are major molecules which are critical in the function and regulation of iron.
The key factors driving growth of the global IV iron industry include escalating number of dialysis and hypertension cases, ameliorating
economic conditions, increasing global healthcare expenditures, and rising medicines expenditures. Some of the noteworthy trends
and developments of this industry encompass novel product development, bundled payment systems and increasing penetration of
genecology sector. However, the growth of this industrial sector is being hindered by stringent regulatory structures and adverse
affects associated with the use of IV iron products.
The report analyzes the global iron product industry along with an extensive coverage of global and the US IV iron market. The global
IV iron market witnesses intense competition with numerous top notch players; such as Galenica Pharmaceuticals, Actavis Inc, AMAG
Pharmaceuticals; operating in the marketplace along with small budding players. As a part of analysis of fierce competition prevailing
in the industry product contention has been presented in the report. The company profiles of leading aforementioned players in the
market are also incorporated in the report.
By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of
the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS
Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several
independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and
tests.
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3. Iron products are chiefly divided into two types: oral and intravenous and it is noteworthy that the global
iron products market is dominated by oral products due to easy of usage.
• After witnessing a mild decline in 2012 due to unfavorable
exchange rates, the global iron product market was valued at
US$.... billion at the end of 2013. This marked an incline of ….%,
compared to US$.… billion during the previous year. In addition to
this, the overall growth was noted at a noteworthy CAGR of ….%
from US$.... billion in 2009 to US$..... billion in 2013.
•Oral iron products held ….% share of the total revenue generated
by the global iron products industry whist intravenous products
accounted for remaining ….% share.
• In terms of value, oral iron products contributed US$.... billion to
the global iron product industry at the end of 2013. Intravenous iron
products accounted for US$.... billion out of the aforementioned
industry.
Global Iron Products Value – by Segments (2013)
Global Iron Products Market Share – by Segments (2013)
Global Iron Products Market (2009-2013)
Oral Intravenous
2009 2010 2011 2012 2013
US$Billion
1.41739663
1.02229597
Oral Intravenous
US$Billion

4. The key factors driving growth of the global IV iron industry include escalating number of dialysis and
hypertension cases, increasing global healthcare expenditures, and rising medicines expenditures.
• There has been a significant increase in the global consumption
of iron replacement products worldwide. The global IV iron market
was worth US$..... million in 2013, up by …..%, compared to
US$.... million in 2012. The growth of global IV iron market was
noted at a CAGR of ….% during the period spanning 2009 to 2013.
• The IV iron market in the US has been steadily increasing over
the past couple of years. The US IV iron market marked an incline
of ….% to reach US$.... million at the end of 2013, compared to
US$.... million in the prior year. The incline in the US marketplace
was chiefly due to ameliorating economic conditions thereby fueling
the spending power of individuals on healthcare.
• The US non-dialysis IV iron replacement has been slowly but
steadily increasing since 2011. On an estimated basis, the size of
the total 2013 the US non-dialysis IV iron replacement therapy
market was approximately ….. grams, which depicted an increase
of …..% over 2012 when the size was ……. grams.
US Non-Dialysis IV Iron Market (2011-2013)
The US IV Iron Market Size (2009-2013)
Global IV Iron Market (2009-2013)
2009 2010 2011 2012 2013
US$Million
2011
2012
2013
Grams
2009 2010 2011 2012 2013
US$Billion

5. Some of the major areas of IV iron application include gynecology, gastroenterology, oncology and
surgeries, apart from others.
 It is anticipated that in 2013, Venofer Fresenius Kabi Branded Generic held …..% share of the totak IV Iron market in the US, followed by
…..% share of Venofer Luitpold Inc Brand. Feraheme AMAG Pharm Branded Generic represented …..% share. Apart from the aforementioned
products, other products which depicted a significant share on the US marketplace were Infed Watson Pharma Branded Generic, Ferrlecit
Sanofi Aventis Branded Generic, depicting ….% share each, and Nulecit Watson Pharma Branded Generic, representing ….% share. As of
first quarter of 2014, Venofer was the leading product in the US non-dialysis IV iron market with ….% share followed by Iron
Dextran/Dexferrum with ….% share. Other leading products forming the US non-dialysis IV iron market encompass Feraheme, Ferric
Gluconate, and Injectafer.
 Intravenous iron therapies find maximum use in nephrology segment, as a high percentage of the patients suffering from chronic kidney
diseases or CKD require them, owing to the low absorption of iron and decline in appetite due to kidney failure. In addition, patients who suffer
from ESRD and undergo dialysis are the major consumers of IV iron products. This segment is expected to further benefit the global IV iron
market in the coming years, chiefly due to an expected increase in the number of CKD and dialysis patients worldwide. All the factors
mentioned above are certain to boost the performance of the global IV iron market, which is forecasted to reach US$...... million by the end of
2018 from US$..... million in 2013. During the five year period from 2013 to 2018, the global market for IV iron is expected to grow at a CAGR
of …..%.
Note: Market attractiveness is inverse of penetration. Low penetration means high attractiveness and vice-versa
Venofer Fresenius Kabi Branded Generic
Venofer Luitpold Pharm Inc. Brand
Feraheme AMAG Pharm Branded Generic
Infed Watson Pharma Branded Generic
Ferrlecit Sanofi Aventis Branded Generic
Nulecit Watson Pharma Branded Generic
Others
IV Iron Market Share in the US (2013E)
2009
2010
2011
2012
2013
2014F
2015F
2016F
2017F
2018F
US$Million
Global IV Iron Market Forecast (2009-2018F)

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Vikas Gupta
BD Manager
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