1. Amyloid Precursor Protein (APP) The effects of overproduction in Alzheimer’s and Downs Syndrome Taylor Griffith, Rachel Christman, Shanley Besett, Christa Franz

5. Membrane Protein  Plaque Cut pieces of APP aggregate in ECF as amyloid plaque and can signal cell death Integral transmembrane protein Proteases lyse APP into components that enter either the ICF or ECF Figures retrieved 4/16/08: http://www.rienstraclinic.com/newsletter/2006/2006Nov.html