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Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
Human embryonic stem cells (hESCs) are stem cells derived from the inner cell mass of a blastocyst, which is
a stage reached four to five days post-fertilization. Human embryonic stem cells are the most pluripotent of all
stem cell types and can develop into over 200 different cell types of the human body.
Human embryonic stem cells were first derived from mouse embryos in 1981 by Martin Evans and Matthew
Kaufman, and independently by Gail R. Martin. In 1995, the first successful culturing of embryonic stem cells
from non-human primates occurred at the University of Wisconsin-Madison. Another breakthrough followed
at the University of Wisconsin-Madison in November 1998 when a group led by Dr. James Thomson
developed a technique to isolate and grow hESCs derived from human blastocysts. Federal funds to support
hESC research became available on August 9, 2001, when President Bush announced his decision regarding
federal funding for hESC research.
Because of their plasticity and unlimited capacity for self-renewal, hESCs have been proposed for use in wide
range of applications, including toxicology testing, tissue engineering, cellular therapies, and basic stem cell
biology research. Of particular interest to the medical community is the potential for use of hESCs to heal
tissues with naturally limited capacity for renewal, such as the human heart, liver and brain.
However, human embryonic stem cell research is heavily encumbered by patents held by the University of
Wisconsin's Wisconsin Alumni Research Foundation (WARF), which creates significant challenges for
companies seeking to develop new products.
This market research report explores the complex IP landscape affecting development of human embryonic
stem cell products, providing clear guidance for companies entering or already within the market, from
collaborating with WARF to less costly alternatives such as circumventing the claims, conducting research
off-shore, and developing embryonic stem cell products for other species.
Key Findings Include:
Trends for hESC Grants, Scientific Publications, and Patents Market Size Determination for the hESC
Product Market 5-Year Market Size Projections (2013-2017) Embryonic Stem Cell Patent Restrictions and
Strategies to Circumvent Claims Geographical Breakdown (Leading Countries Conducting hESC Research)
Breakdown of Embryonic Stem Cell Research, by Application and Species Competitive Analysis of hESC
Research Supply Vendors Overview of Specialty Pharma Companies Developing Embryonic Stem Cell
Therapies Overview of Toxicology Testing Legislation (impacting use of hESC in toxicology applications)
Crucial Trends and Unmet Market Needs
And Much More
In summary, this is a must-read industry report for biotech and pharma companies to optimally position
themselves to sell hESC products. To profit from this lucrative and rapidly expanding market, you need to
understand your key strengths relative to the competition, intelligently position your products to fill gaps in
the market place, and take advantage crucial hESC trends. Claim this report now to profit from this expanding
market or your competition will.
table Of Content
Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
i. Background
a. Human Embryonic Stem Cells (hesc)
b. Brief History
c. Use In Treatment Of Disease
d. Human Embryonic Stem Cell Line Availability
ii. Available Stem Cell Lines
a. Nih Registry Approved
b. Sources Of Additional Published Hesc Lines
c. Sources Of Additional Unpublished Hesc Lines
iii. Applications
a. Basic Stem Cell Biology
b. Cellular Therapies
1. Overview
2. Heart Regeneration
3. Pancreatic Islet Cell Replacement
4. Neural Regeneration C. Tissue Engineering
d. Toxicology Testing
iv. Application Priorities
a. Overall
1. Cell-based Therapies: Greatest Shared Priority Across Research Community
a. Beneficial Hesc Characteristics
b. Hesc Safety Concerns
c. Hesc Characterization In Vitro
d. Hesc Characterization In Vivo
2. Toxicology Assessment: Another Area Of Huge Potential
a. Overview
b. Commercial Interest
b. By Segment
1. Academic
2. Biotech
3. Pharma
v. Patent Environment
a. Landmark Hesc Patents: Warf “composition Of Matter” Patents
1. Background
2. Licensing Of Warf Patent Rights
Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
a. Overview Of Warf Licensees
b. Recent Warf Licensee: Pfizer, Inc.
3. Warf Patent Exemption: Federal Rights To Hesc Research
4. U.s. Warf Patent Challenges
5. Circumventing Warf Patent Rights Using Geographic Limitations
b. Global Stem Cell Patent Landscape
c. U.s. Patents Of Importance
1. Geron Corporation Patents
2. Regents Of The University Of California Patents
3. Bresagen, Inc. Patents
4. Regeneron Pharmaceuticals, Inc.
5. Vanderbuilt University Patents
d. Worldwide Patents Of Importance
1. Es Cell International Pte Ltd. Patents (singapore)
2. Dnavec Research Inc. Patents (ibaraki, Jp)
3. University Of Edinburgh Patents (edinburgh, Gb)
e. Summary Of The Hesc Intellectual Property Landscape
vi. Historical And Future Growth Projections
a. Scientific Publication Analysis
1. Historical Analysis (trailing 10 Years)
2. Future Growth Predictions (5-year Forecasts)
3. Breakdown Of Esc Research By Species
b. Grant Analysis
c. Patent Analysis
1. All Fields
2. Abstract Only
d. Market Size Quantification
e. Key Research Applications
1. Size Of Market Segments
2. Trend Data
f. Geographical Breakdown (leading Countries Conducting Hesc Research)
vii. Hesc Product Competitors
a. Cellartis Ab
1. Human Embryonic Stem Cell Lines
2. Monoclonal Antibodies For Hesc Research
3. Differentiated Cell Products
4. Associated Hesc Products
b. Vitrolife
c. Tataa Biocenter
Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
d. Invitrogen
1. Hesc Culture Media & Reagents
2. Hesc-qualified Basement Membrane Extract
3. Hesc Cdna Libraries
4. Hesc Reporter Cells
5. Hesc Pcr Kits
6. Hesc Stem Cell Antibodies
7. Hesc Stem Cell Growth Factors
e. Stem Cell Technologies
1. Hesc Culture Media & Reagents
2. Hesc Primary & Secondary Antibodies
f. Bd Biosciences
g. Chemicon
1. Hesc Culture Media And Reagents
2. Hesc Lines
3. Hesc Kits
4. Hesc Antibodies
h. R&d Systems
i. Sa Biosciences
j. Thermo Scientific
k. Australian Stem Cell Centre
viii. Specialty Pharmaceutical Companies Developing Hesc Therapies
a. Geron
b. Novocell
c. Cell Cure Neurosciences Ltd
d. Cell Dynamics International
e. Advanced Cell Technology
ix. Featured Labs (potential Customers)
a. Academic Labs
b. Private Labs
c. Government Labs
d. International Labs
x. Toxicology Testing Legislation
a. European Union To Ban Animal-testing For Cosmetic Development In 2009
b. Responses To The European Ban On Animal Testing For Cosmetic Development
1. Overview
2. Skin Irritation
Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
3. Eye Irritation
4. Skin Sensitisation
5. Mutagenicity/genotoxicity
6. Reproductive Toxicity
c. Eu Legislation Regarding Animal-based Testing For Drug Discovery
xi. Product Development Guidance
a. Product Categories
1. Hescs
2. Hesc Derivative Cells
3. Hesc Reporter Cells
4. Hesc Antibodies
5. Hesc Characterization & Pcr Kits
6. Hesc Qualified Bme
7. Hesc Cdna Libraries
8. Hesc Growth Factors
9. Hesc Media And Culture Reagents
b. Product Ideas & Suggestions
1. Areas Of Underdeveloped Competition
2. Mouse Esc Products
3. Ips Cells Products
4. Non-animal-derived Culture Reagents For Hescs
5. Strategic Collaborations
6. Products For Generating Pure Esc Populations
7. Hesc Toxicity Assay Kit
xii. Events Of Interest
a. Adult Stem Cell Therapy & Regenerative Medicine
b. 2013 Society For Hematology And Stem Cells, 42nd Annual Scientific Meeting
c. Stem Cells In Translation
d. Life Cycle Of Stem Cell Therapies
e. Stem Cells In Science And Medicine
f. 8th Annual Translational Stem Cell Research Conference
g. Shanghai International Symposium On Cancer Stem Cells
h. Stem Cell Congress 2013
i. 1st Annual Conference Of The German Stem Cell Network (gscn)
j. Stem Cell Society Singapore (scss) Symposium 2013
k. Cell Symposia: Using Stem Cells To Model And Treat Human Disease
l. World Stem Cell Summit 2013
m. Stem Cells And Reprogramming
Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
appendix. Human Embryonic Stem Cell Research Centers And Contact Information
ResearchMoz(http://www.researchmoz.us/) is the one stop online destination to find and buy market research
reports & Industry Analysis. We fulfill all your research needs spanning across industry verticals with our
huge collection of market research reports. We provide our services to all sizes of organizations and across all
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Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017

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Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts | Researchmoz

  • 1. Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017 Human embryonic stem cells (hESCs) are stem cells derived from the inner cell mass of a blastocyst, which is a stage reached four to five days post-fertilization. Human embryonic stem cells are the most pluripotent of all stem cell types and can develop into over 200 different cell types of the human body. Human embryonic stem cells were first derived from mouse embryos in 1981 by Martin Evans and Matthew Kaufman, and independently by Gail R. Martin. In 1995, the first successful culturing of embryonic stem cells from non-human primates occurred at the University of Wisconsin-Madison. Another breakthrough followed at the University of Wisconsin-Madison in November 1998 when a group led by Dr. James Thomson developed a technique to isolate and grow hESCs derived from human blastocysts. Federal funds to support hESC research became available on August 9, 2001, when President Bush announced his decision regarding federal funding for hESC research. Because of their plasticity and unlimited capacity for self-renewal, hESCs have been proposed for use in wide range of applications, including toxicology testing, tissue engineering, cellular therapies, and basic stem cell biology research. Of particular interest to the medical community is the potential for use of hESCs to heal tissues with naturally limited capacity for renewal, such as the human heart, liver and brain. However, human embryonic stem cell research is heavily encumbered by patents held by the University of Wisconsin's Wisconsin Alumni Research Foundation (WARF), which creates significant challenges for companies seeking to develop new products. This market research report explores the complex IP landscape affecting development of human embryonic stem cell products, providing clear guidance for companies entering or already within the market, from collaborating with WARF to less costly alternatives such as circumventing the claims, conducting research off-shore, and developing embryonic stem cell products for other species. Key Findings Include: Trends for hESC Grants, Scientific Publications, and Patents Market Size Determination for the hESC Product Market 5-Year Market Size Projections (2013-2017) Embryonic Stem Cell Patent Restrictions and Strategies to Circumvent Claims Geographical Breakdown (Leading Countries Conducting hESC Research) Breakdown of Embryonic Stem Cell Research, by Application and Species Competitive Analysis of hESC Research Supply Vendors Overview of Specialty Pharma Companies Developing Embryonic Stem Cell Therapies Overview of Toxicology Testing Legislation (impacting use of hESC in toxicology applications) Crucial Trends and Unmet Market Needs And Much More In summary, this is a must-read industry report for biotech and pharma companies to optimally position themselves to sell hESC products. To profit from this lucrative and rapidly expanding market, you need to understand your key strengths relative to the competition, intelligently position your products to fill gaps in the market place, and take advantage crucial hESC trends. Claim this report now to profit from this expanding market or your competition will. table Of Content Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
  • 2. i. Background a. Human Embryonic Stem Cells (hesc) b. Brief History c. Use In Treatment Of Disease d. Human Embryonic Stem Cell Line Availability ii. Available Stem Cell Lines a. Nih Registry Approved b. Sources Of Additional Published Hesc Lines c. Sources Of Additional Unpublished Hesc Lines iii. Applications a. Basic Stem Cell Biology b. Cellular Therapies 1. Overview 2. Heart Regeneration 3. Pancreatic Islet Cell Replacement 4. Neural Regeneration C. Tissue Engineering d. Toxicology Testing iv. Application Priorities a. Overall 1. Cell-based Therapies: Greatest Shared Priority Across Research Community a. Beneficial Hesc Characteristics b. Hesc Safety Concerns c. Hesc Characterization In Vitro d. Hesc Characterization In Vivo 2. Toxicology Assessment: Another Area Of Huge Potential a. Overview b. Commercial Interest b. By Segment 1. Academic 2. Biotech 3. Pharma v. Patent Environment a. Landmark Hesc Patents: Warf “composition Of Matter” Patents 1. Background 2. Licensing Of Warf Patent Rights Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
  • 3. a. Overview Of Warf Licensees b. Recent Warf Licensee: Pfizer, Inc. 3. Warf Patent Exemption: Federal Rights To Hesc Research 4. U.s. Warf Patent Challenges 5. Circumventing Warf Patent Rights Using Geographic Limitations b. Global Stem Cell Patent Landscape c. U.s. Patents Of Importance 1. Geron Corporation Patents 2. Regents Of The University Of California Patents 3. Bresagen, Inc. Patents 4. Regeneron Pharmaceuticals, Inc. 5. Vanderbuilt University Patents d. Worldwide Patents Of Importance 1. Es Cell International Pte Ltd. Patents (singapore) 2. Dnavec Research Inc. Patents (ibaraki, Jp) 3. University Of Edinburgh Patents (edinburgh, Gb) e. Summary Of The Hesc Intellectual Property Landscape vi. Historical And Future Growth Projections a. Scientific Publication Analysis 1. Historical Analysis (trailing 10 Years) 2. Future Growth Predictions (5-year Forecasts) 3. Breakdown Of Esc Research By Species b. Grant Analysis c. Patent Analysis 1. All Fields 2. Abstract Only d. Market Size Quantification e. Key Research Applications 1. Size Of Market Segments 2. Trend Data f. Geographical Breakdown (leading Countries Conducting Hesc Research) vii. Hesc Product Competitors a. Cellartis Ab 1. Human Embryonic Stem Cell Lines 2. Monoclonal Antibodies For Hesc Research 3. Differentiated Cell Products 4. Associated Hesc Products b. Vitrolife c. Tataa Biocenter Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
  • 4. d. Invitrogen 1. Hesc Culture Media & Reagents 2. Hesc-qualified Basement Membrane Extract 3. Hesc Cdna Libraries 4. Hesc Reporter Cells 5. Hesc Pcr Kits 6. Hesc Stem Cell Antibodies 7. Hesc Stem Cell Growth Factors e. Stem Cell Technologies 1. Hesc Culture Media & Reagents 2. Hesc Primary & Secondary Antibodies f. Bd Biosciences g. Chemicon 1. Hesc Culture Media And Reagents 2. Hesc Lines 3. Hesc Kits 4. Hesc Antibodies h. R&d Systems i. Sa Biosciences j. Thermo Scientific k. Australian Stem Cell Centre viii. Specialty Pharmaceutical Companies Developing Hesc Therapies a. Geron b. Novocell c. Cell Cure Neurosciences Ltd d. Cell Dynamics International e. Advanced Cell Technology ix. Featured Labs (potential Customers) a. Academic Labs b. Private Labs c. Government Labs d. International Labs x. Toxicology Testing Legislation a. European Union To Ban Animal-testing For Cosmetic Development In 2009 b. Responses To The European Ban On Animal Testing For Cosmetic Development 1. Overview 2. Skin Irritation Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
  • 5. 3. Eye Irritation 4. Skin Sensitisation 5. Mutagenicity/genotoxicity 6. Reproductive Toxicity c. Eu Legislation Regarding Animal-based Testing For Drug Discovery xi. Product Development Guidance a. Product Categories 1. Hescs 2. Hesc Derivative Cells 3. Hesc Reporter Cells 4. Hesc Antibodies 5. Hesc Characterization & Pcr Kits 6. Hesc Qualified Bme 7. Hesc Cdna Libraries 8. Hesc Growth Factors 9. Hesc Media And Culture Reagents b. Product Ideas & Suggestions 1. Areas Of Underdeveloped Competition 2. Mouse Esc Products 3. Ips Cells Products 4. Non-animal-derived Culture Reagents For Hescs 5. Strategic Collaborations 6. Products For Generating Pure Esc Populations 7. Hesc Toxicity Assay Kit xii. Events Of Interest a. Adult Stem Cell Therapy & Regenerative Medicine b. 2013 Society For Hematology And Stem Cells, 42nd Annual Scientific Meeting c. Stem Cells In Translation d. Life Cycle Of Stem Cell Therapies e. Stem Cells In Science And Medicine f. 8th Annual Translational Stem Cell Research Conference g. Shanghai International Symposium On Cancer Stem Cells h. Stem Cell Congress 2013 i. 1st Annual Conference Of The German Stem Cell Network (gscn) j. Stem Cell Society Singapore (scss) Symposium 2013 k. Cell Symposia: Using Stem Cells To Model And Treat Human Disease l. World Stem Cell Summit 2013 m. Stem Cells And Reprogramming Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017
  • 6. appendix. Human Embryonic Stem Cell Research Centers And Contact Information ResearchMoz(http://www.researchmoz.us/) is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfill all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organizations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price. Contact: M/s Sheela, 90 State Street, Suite 700, Albany NY - 12207 United States Tel: +1-518-618-1030 USA - Canada Toll Free 866-997-4948 Email: sales@researchmoz.us Website: http://www.researchmoz.us/ Opportunities in Human Embryonic Stem Cell (hESC) Products - Trends and Forecasts to 2017