Cp Rounds Factor V Leiden & Pregnancy

Factor V Leiden & Pregnancy Karl Robstad, MD Albany Medical Center Department of Pathology

Causes of inherited thrombophilia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Demographics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Sequellae ,[object Object],[object Object],[object Object]

Additional risk factors ,[object Object],[object Object],[object Object],[object Object]

[object Object],0.02 2.8 Prothrombin mutation 0.02 2.5 Hyperhomocysteinemia 0.5 – 1.0 80 FVL homozygous 0.29 35 FVL heterozygous + OCP 0.03 4 Oral contraceptive pills 0.06 7 Factor V Leiden heterozygous 0.008 1 Normal Incidence (% per year) Relative risk Condition

Normal Physiology ,[object Object],[object Object]

Coagulation cascade: schematic

Genetics ,[object Object],[object Object],[object Object]

Recommendations for Testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Consideration for Testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Screening for Factor V Leiden ,[object Object],[object Object],[object Object],[object Object],[object Object]

Factor V Leiden: Treatment ,[object Object],[object Object]

Factor V Leiden: Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]

FVL and Pregnancy ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pregnancy ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pregnancy ,[object Object],[object Object]

Case Study ,[object Object],[object Object],[object Object],[object Object]

Treatment in Pregnancy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment in Pregnancy ,[object Object],[object Object],[object Object],[object Object]

References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Cp Rounds Factor V Leiden & Pregnancy

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