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Dr. Alba Lidia Pupo Gutiérrez
    Associated Professor
Specialist of Human Anatomy
Summary:
INTRODUCTION TO NERVOUS SYSTEM.
SPINAL MEDULLA
       - Generalities of nervous system.
Gray and White matters, properties of the
nervous system.
     - Spinal cord or medulla, extension,
external and internal configuration.
Meninges.
NERVOUS SYSTEM

         Is the most
         complex physical
         system know to
         mankind.
Excitability.
Properties
             Conduction.



             Afferent.
Functions    Analysis and integration.
             Efferent.
SUBDIVISION OF NERVOUS SYSTEM


• Topography or Descriptional:
   - Central and peripheral

• Functional:
   - Autonomic and Somatic

• Philogenetic:
   - Segmentary and suprasegmentary
SUBDIVISION OF NERVOUS SYSTEM


                     Central.
  I. Topography
                     Peripheral

                Brain
   Central      Spinal medulla.

                   Spinal nerves.
                   Cranial nerves
   Peripheral
                   Peripheral part of the
                   autonomic nervous system
Somatic.
 II. Functional       Autonomic.



Somatic: In relation with the innervation of the
osteomioarticular system


Autonomic: In relation with visceral innervation.
Segmentary.
    III. Philogenetic     Suprasegmentary.


Segmentary. Afferent or efferent directly relation with
periphery (Spinal medulla and brainstem)


Suprasegmentary. Afferent or efferent relation through
third neuron (Cerebelum, diencephalon and
telencephalon) .
Suprasegmentary     Diencephalon
  Telencephalon

Segmentary
Medulla oblongata
Pons
Mesencephalon                 Cerebellum


 Spinal medulla
NEURON
       S
Body

            Prolongations:
              - Axon
              - Dendrites
Bodies                             Grouped

   Grey matter
                                Central     Peripheral

                                Nuclei        Ganglia
  The cells bodies of neurons
are often grouped or they may
 form more extensive layers               Layers
       or mases of cells
          collectively

                                          Cortex
Ganglia

Peripheral Nervous System


   Sensitive            Vegetative

Spinal or cranial    Cranial nerves and
    nerves           sympathetic chain
PROLONGATIONS
                        Central
 White matter

                  Tracts or funiculus
                        Peripheral
  Nerve fibers

                 Root             Plexus

                         Nerves
REFLEX ARCH. COMPONENTS



           Afferent




           Efferent
Bineuronal Reflex Arc



Receptor
Transform the stimulus in
 Receptor: nervous impulse.


Types:




  Interior               Exterior
 receptors              receptors
Bineuronal Reflex
 Arch

Receptor

Sensitives
Fiber
Sensitives fibers or afferents




 Convey informations
              to
           Center
Bineuronal Reflex Arc
              Sensitive neuron


 Receptor
 Sensitives
  fibres
Sensitive neuron:



         In
sensitives ganglias
Bineuronal Reflex Arch
             Sensitive neuron


Receptor
Sensitives
                                Motor
Fibres
                                Neuron
Motor neuron

    Transmit the orders

  In Central Nervous System
           or ganglia
in Vegetative Nervous System
Bineuronal Reflex Arch
             Sensitive neuron


 Receptor
Sensitives                      Motor
  fibers                        neuron

                                Motors
                                fibers
Motors fibers or efferents



Convey Information to
    effector organ
Bineuronal Reflex Arch
             Sensitive neuron


 Receptor
Sensitives                      Motor
  fibers                        neuron

Effector
                                Motors
                                fibers
Effector

Produces an effect


   Muscles           Glands
Bineuronal Reflex Arch
             Sensitive neuron


 Receptor
Sensitives                      Motor
  fibers                        neuron

Effector
                                Motors
                                fibers
Trineuronal Reflex Arch
             Sensitive neuron

                                Connector
 Receptor
                                 Neuron
Sensitives                        Motor
 fibers                           neuron

Effector
                                  Motors
                                  fibers
Connector neuron
 Central Nervous System

        Between the
sensitive and motor neuron
Vegetative Reflex Arch

Sensitive neuron   Central Efferent Neuron



                   Peripheral
                   Efferent Neuron
                   Receptor
                   (interior
                   receptor)
Central Nervous System
 External Configuration
   Details of the surface
      of portions of
     Nervous System
Example
 Posterior
 Median
 sulcus


                Posterolateral
Anterior              Sulcus
median
fissure


Anterolateral
Sulcus
Internal configuration


     •   Grey matter

    • White matter
Example:
White matter
               Grey matter
Grey matter

-Nuclei
-Column
-Cortex
Tracts or funiculus

Fibers in Central Nervous System

Transporting the same information



  Lemmniscis: Medulla oblongata
              Pons
              Mesencephalon
Types of tracts:

  Afferents          Efferents

  Spinocerebellars
  Posterior                 Gracillis
  Anterior
                          Cuneatus
Nervous center




                    Eff
                       ere
                          nts
           A
        ff
     ere
 st n




Receptors         Effectors

        Nervous pathways
Partial summary
• The Nervous system is derived form the ectodermun.
• The neuron is the structural unit of the Nervous system
   and the reflex arch is the morphofunctional unit.
• The Nervous system is organized in grey and white matter.
• The grey matter in the Central nervous system form nuclei
and cortex while the white matter form tracts and funiculus.
 • The grey matter is form by the bodies of neuron.
• The Nervous system are divided according to the
topography, functions and philogenetic aspects.
• The reflex arch can be simple if participate two neurons and
complex if participate more of two neurons.
SPINAL MEDULLA
• Is an elongated part of the Central Nervous
  System.
• Situated inside the vertebral canal
• Length: 45 cm
• Extends from the foramen magnum at the
  base of the skull to the junction between the
  first and second lumbar vertebrae.
• Continuous cranially with the medulla
  oblongata
• 31 segments
External configuration
•   Ventral surface
•   Dorsal surface
•   Conus medullaris
•   Filum terminale
•   Cervical enlargement
•   Lumbar enlargement
1. Cervical
   enlargement

2. Lumbar
   enlargement

3. Conus medullaris

4. Filum terminale
• Cervical enlargement: Supplying
  the upper limbs and extends from
  the third cervical to the second
  thoracic segments.

• Lumbar enlargement corresponds
  to the innervation of the lower
  limbs, extending from the first
  lumbar to the third sacral
  segment.
Ventral surface
• Anterior median
  fissure
• Anterolateral
  sulcus: Ventral
  spinal roots
• Anterior funiculus
• Lateral funiculus
Dorsal surface
• Posterior median sulcus
• Posterolateral sulcus: Dorsal
  roots of spinal nerves enter
  the cord
• Posterior funiculus: In
  cervical and upper thoracic
  segments a longitudinal
  posteriorintermediate sulcus
  dividing into two large tracts:
  - Fasciculus gracilis (medial)
  - Fasciculus cuneatus (lateral)
Posterior
Fasciculus gracilis   intermediate
                      sulcus

                            Fasciculus cuneatus
Internal configuration
• Grey matter
                                Right   Left
• Is central: Column
• In transverse sections this
  column are connected by
  a narrow transverse grey
  commissure, the whole
  resembling a letter H.
• The commissure is
  traversed by the central
  canal.
-Anterior and posterior
columns
-Some levels: Lateral
column (between the
second thoracic and first
lumbar spinal cord
segments).
-In transverse sections
the columns appear as
projections and called
horns
Internal configuration                  Thoracic




                        Lateral horns

             Cervical                   Lumbar

      Posterior horns


      Grey
    comissura
                                         Sacral
      Anterior horns
1. White matter
2. Posterointermediate
   sulcus
3. Lateral funicullus
4. Anterior horn
5. Lateral horn
6. Posterior horn
7. Central canal
8. White commissure
9. Central grey matter
Neuronal groups of the anterior
         grey columns


• Nucleus lateral

• Nucleus medial
Neuronal groups of the posterior
             grey columns

•   Substantia gelatinosa (of Rolando)
•   Dorsal funicular group or nucleus propius
•   Nucleus dorsalis or thoracicus
•   Nucleus centrobasalis
Neuronal groups of the lateral
          grey columns


• Nucleus intermediate lateral
Substantia gelatinosa


                             Nucleus propius
 Nucleus thoracicus
                             Nucleus intermediate lateral




Nucleus lateral and medial
White matter
• Central grey matter is
  surrounded by white
  matter, consisting of
  nerve fibers, and
  grouped into funiculi
• Dorsal, lateral and
  ventral funiculi.
FUNICULUS OF THE SPINAL CORD.

            Dorsal




  Lateral




                Ventral
Ascending tracts
• Dorsal funiculus:
1. Fasciculi gracilis
2. Fasciculi cuneatus
• Lateral funiculus:
1. Posterior spinocerebellar tract
2. Anterior spinocerebellar tract
• Anterior funiculus:
1. Spinothalamic tracts
Descending tracts
• Anterior funiculus:
  - Anterior corticospinal tract
  - Vestibulospinal tracts
  - Reticulospinal tracts
  - Tectospinal tract
• Lateral funiculus:
  - Rubrospinal tract
  - Lateral corticospinal tract
TRACTS OF WHITE MATTER IN
    THE SPINAL MEDULLA.
                      Fasciculi gracilis and cuneatus

                                            Lateral corticospinal


Anterior and posterior spinocerebellar tracts



                                        Anterior corticospinal


Anterior and lateral spinothalamic tracts
Central canal
• Opening above into
  the fourth ventricle.
• In the conus
  medullaris it expands
  as a fusiform terminal
  ventricle.
• It contains Cerebral
  Spinal Fluid (CSF)
The spinal cord are surrounded by three
membranes: the meninges.
Comprise the duramater (pachymeninx) and
the leptomeninges: the arachnoid mater
and pia mater.
PACHYMENINX - DURA MATER
Is the most external of the meninges.
Spinal dura mater
• The periosteum of the vertebral canal is
  separated from the spinal dura mater by an
  extradural (epidural) space.
• Extradural (epidural) space: it contains
  loose connective tissue, fat and venous
  plexus.
Subdural space
• Between the spinal dura and arachnoid mater
   LEPTOMENINGES- ARACHNOID
       AND PIA MATER
Arachnoid mater: Surrounding the spinal cord is
 continuous with the cranial arachnoid mater.
 Arachnoid villi
Spinal pia mater: Closely the surface of the spinal
 cord and passes into the anterior median fissure.
 They are separated by the subarachnoid
 space (CSF)
Arachnoid   Dura mater
Epidural space
           Subdural space

                 Subarachnoid space
Subarachnoid space
Subarachnoid cisterns
     - Cisterna terminalis
ARTERIAL BLOOD SUPPLY OF THE
        SPINAL CORD


Branches of the vertebral, deep cervical,
intercostal and lumbar arteries; these, with
the anterior and posterior spinal arteries,
form longitudinal anastomotic channels
along the cord.
Spinal posterior arteries
Spinal anterior arteries
VENOUS DRAINAGE
Spinal veins drain into plexiform
longitudinal channels.
These vessels connect together
with the cerebellar veins and
cranial sinuses.
MAGNETIC RESONANCE IN FRONTAL SECTION OF THE
    SPINAL MEDULLA IN CERVICAL REGION




          Enlargement

                           Cervical spinal medulla
CONCLUSION
• The spinal medulla is a segmentary structure of the Central
  nervous system that transmit the nervous impulses from and to
  the suprasegments.
• The grey matter is situated in the central part as columns
  constituted by nucleus of motor neuron, somatic or autonomic
  and sensitives.
• The white matter is situated surround the grey matter in
  funiculus and form ascendent and descendent tracts.
• The meninges are membranes of connective tissue that
  protective structures of the Central nervous system with spaces
  between their.
BRAIN STEM. CEREBELLUM

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Nervous system

  • 1. Dr. Alba Lidia Pupo Gutiérrez Associated Professor Specialist of Human Anatomy
  • 2.
  • 3. Summary: INTRODUCTION TO NERVOUS SYSTEM. SPINAL MEDULLA - Generalities of nervous system. Gray and White matters, properties of the nervous system. - Spinal cord or medulla, extension, external and internal configuration. Meninges.
  • 4. NERVOUS SYSTEM Is the most complex physical system know to mankind.
  • 5. Excitability. Properties Conduction. Afferent. Functions Analysis and integration. Efferent.
  • 6. SUBDIVISION OF NERVOUS SYSTEM • Topography or Descriptional: - Central and peripheral • Functional: - Autonomic and Somatic • Philogenetic: - Segmentary and suprasegmentary
  • 7. SUBDIVISION OF NERVOUS SYSTEM Central. I. Topography Peripheral Brain Central Spinal medulla. Spinal nerves. Cranial nerves Peripheral Peripheral part of the autonomic nervous system
  • 8. Somatic. II. Functional Autonomic. Somatic: In relation with the innervation of the osteomioarticular system Autonomic: In relation with visceral innervation.
  • 9. Segmentary. III. Philogenetic Suprasegmentary. Segmentary. Afferent or efferent directly relation with periphery (Spinal medulla and brainstem) Suprasegmentary. Afferent or efferent relation through third neuron (Cerebelum, diencephalon and telencephalon) .
  • 10. Suprasegmentary Diencephalon Telencephalon Segmentary Medulla oblongata Pons Mesencephalon Cerebellum Spinal medulla
  • 11. NEURON S Body Prolongations: - Axon - Dendrites
  • 12. Bodies Grouped Grey matter Central Peripheral Nuclei Ganglia The cells bodies of neurons are often grouped or they may form more extensive layers Layers or mases of cells collectively Cortex
  • 13. Ganglia Peripheral Nervous System Sensitive Vegetative Spinal or cranial Cranial nerves and nerves sympathetic chain
  • 14. PROLONGATIONS Central White matter Tracts or funiculus Peripheral Nerve fibers Root Plexus Nerves
  • 15. REFLEX ARCH. COMPONENTS Afferent Efferent
  • 17. Transform the stimulus in Receptor: nervous impulse. Types: Interior Exterior receptors receptors
  • 19. Sensitives fibers or afferents Convey informations to Center
  • 20. Bineuronal Reflex Arc Sensitive neuron Receptor Sensitives fibres
  • 21. Sensitive neuron: In sensitives ganglias
  • 22. Bineuronal Reflex Arch Sensitive neuron Receptor Sensitives Motor Fibres Neuron
  • 23. Motor neuron Transmit the orders In Central Nervous System or ganglia in Vegetative Nervous System
  • 24. Bineuronal Reflex Arch Sensitive neuron Receptor Sensitives Motor fibers neuron Motors fibers
  • 25. Motors fibers or efferents Convey Information to effector organ
  • 26. Bineuronal Reflex Arch Sensitive neuron Receptor Sensitives Motor fibers neuron Effector Motors fibers
  • 27. Effector Produces an effect Muscles Glands
  • 28. Bineuronal Reflex Arch Sensitive neuron Receptor Sensitives Motor fibers neuron Effector Motors fibers
  • 29. Trineuronal Reflex Arch Sensitive neuron Connector Receptor Neuron Sensitives Motor fibers neuron Effector Motors fibers
  • 30. Connector neuron Central Nervous System Between the sensitive and motor neuron
  • 31. Vegetative Reflex Arch Sensitive neuron Central Efferent Neuron Peripheral Efferent Neuron Receptor (interior receptor)
  • 32. Central Nervous System External Configuration Details of the surface of portions of Nervous System
  • 33. Example Posterior Median sulcus Posterolateral Anterior Sulcus median fissure Anterolateral Sulcus
  • 34. Internal configuration • Grey matter • White matter
  • 35. Example: White matter Grey matter
  • 37. Tracts or funiculus Fibers in Central Nervous System Transporting the same information Lemmniscis: Medulla oblongata Pons Mesencephalon
  • 38. Types of tracts: Afferents Efferents Spinocerebellars Posterior Gracillis Anterior Cuneatus
  • 39. Nervous center Eff ere nts A ff ere st n Receptors Effectors Nervous pathways
  • 40. Partial summary • The Nervous system is derived form the ectodermun. • The neuron is the structural unit of the Nervous system and the reflex arch is the morphofunctional unit. • The Nervous system is organized in grey and white matter. • The grey matter in the Central nervous system form nuclei and cortex while the white matter form tracts and funiculus. • The grey matter is form by the bodies of neuron. • The Nervous system are divided according to the topography, functions and philogenetic aspects. • The reflex arch can be simple if participate two neurons and complex if participate more of two neurons.
  • 41.
  • 42. SPINAL MEDULLA • Is an elongated part of the Central Nervous System. • Situated inside the vertebral canal • Length: 45 cm • Extends from the foramen magnum at the base of the skull to the junction between the first and second lumbar vertebrae. • Continuous cranially with the medulla oblongata • 31 segments
  • 43. External configuration • Ventral surface • Dorsal surface • Conus medullaris • Filum terminale • Cervical enlargement • Lumbar enlargement
  • 44. 1. Cervical enlargement 2. Lumbar enlargement 3. Conus medullaris 4. Filum terminale
  • 45. • Cervical enlargement: Supplying the upper limbs and extends from the third cervical to the second thoracic segments. • Lumbar enlargement corresponds to the innervation of the lower limbs, extending from the first lumbar to the third sacral segment.
  • 46. Ventral surface • Anterior median fissure • Anterolateral sulcus: Ventral spinal roots • Anterior funiculus • Lateral funiculus
  • 47. Dorsal surface • Posterior median sulcus • Posterolateral sulcus: Dorsal roots of spinal nerves enter the cord • Posterior funiculus: In cervical and upper thoracic segments a longitudinal posteriorintermediate sulcus dividing into two large tracts: - Fasciculus gracilis (medial) - Fasciculus cuneatus (lateral)
  • 48. Posterior Fasciculus gracilis intermediate sulcus Fasciculus cuneatus
  • 49. Internal configuration • Grey matter Right Left • Is central: Column • In transverse sections this column are connected by a narrow transverse grey commissure, the whole resembling a letter H. • The commissure is traversed by the central canal.
  • 50. -Anterior and posterior columns -Some levels: Lateral column (between the second thoracic and first lumbar spinal cord segments). -In transverse sections the columns appear as projections and called horns
  • 51. Internal configuration Thoracic Lateral horns Cervical Lumbar Posterior horns Grey comissura Sacral Anterior horns
  • 52. 1. White matter 2. Posterointermediate sulcus 3. Lateral funicullus 4. Anterior horn 5. Lateral horn 6. Posterior horn 7. Central canal 8. White commissure 9. Central grey matter
  • 53. Neuronal groups of the anterior grey columns • Nucleus lateral • Nucleus medial
  • 54. Neuronal groups of the posterior grey columns • Substantia gelatinosa (of Rolando) • Dorsal funicular group or nucleus propius • Nucleus dorsalis or thoracicus • Nucleus centrobasalis
  • 55. Neuronal groups of the lateral grey columns • Nucleus intermediate lateral
  • 56. Substantia gelatinosa Nucleus propius Nucleus thoracicus Nucleus intermediate lateral Nucleus lateral and medial
  • 57. White matter • Central grey matter is surrounded by white matter, consisting of nerve fibers, and grouped into funiculi • Dorsal, lateral and ventral funiculi.
  • 58. FUNICULUS OF THE SPINAL CORD. Dorsal Lateral Ventral
  • 59. Ascending tracts • Dorsal funiculus: 1. Fasciculi gracilis 2. Fasciculi cuneatus • Lateral funiculus: 1. Posterior spinocerebellar tract 2. Anterior spinocerebellar tract • Anterior funiculus: 1. Spinothalamic tracts
  • 60. Descending tracts • Anterior funiculus: - Anterior corticospinal tract - Vestibulospinal tracts - Reticulospinal tracts - Tectospinal tract • Lateral funiculus: - Rubrospinal tract - Lateral corticospinal tract
  • 61. TRACTS OF WHITE MATTER IN THE SPINAL MEDULLA. Fasciculi gracilis and cuneatus Lateral corticospinal Anterior and posterior spinocerebellar tracts Anterior corticospinal Anterior and lateral spinothalamic tracts
  • 62. Central canal • Opening above into the fourth ventricle. • In the conus medullaris it expands as a fusiform terminal ventricle. • It contains Cerebral Spinal Fluid (CSF)
  • 63.
  • 64. The spinal cord are surrounded by three membranes: the meninges. Comprise the duramater (pachymeninx) and the leptomeninges: the arachnoid mater and pia mater. PACHYMENINX - DURA MATER Is the most external of the meninges.
  • 65. Spinal dura mater • The periosteum of the vertebral canal is separated from the spinal dura mater by an extradural (epidural) space. • Extradural (epidural) space: it contains loose connective tissue, fat and venous plexus.
  • 66. Subdural space • Between the spinal dura and arachnoid mater LEPTOMENINGES- ARACHNOID AND PIA MATER Arachnoid mater: Surrounding the spinal cord is continuous with the cranial arachnoid mater. Arachnoid villi Spinal pia mater: Closely the surface of the spinal cord and passes into the anterior median fissure. They are separated by the subarachnoid space (CSF)
  • 67. Arachnoid Dura mater
  • 68. Epidural space Subdural space Subarachnoid space
  • 70.
  • 71.
  • 72. ARTERIAL BLOOD SUPPLY OF THE SPINAL CORD Branches of the vertebral, deep cervical, intercostal and lumbar arteries; these, with the anterior and posterior spinal arteries, form longitudinal anastomotic channels along the cord.
  • 73. Spinal posterior arteries Spinal anterior arteries
  • 74. VENOUS DRAINAGE Spinal veins drain into plexiform longitudinal channels. These vessels connect together with the cerebellar veins and cranial sinuses.
  • 75.
  • 76. MAGNETIC RESONANCE IN FRONTAL SECTION OF THE SPINAL MEDULLA IN CERVICAL REGION Enlargement Cervical spinal medulla
  • 77. CONCLUSION • The spinal medulla is a segmentary structure of the Central nervous system that transmit the nervous impulses from and to the suprasegments. • The grey matter is situated in the central part as columns constituted by nucleus of motor neuron, somatic or autonomic and sensitives. • The white matter is situated surround the grey matter in funiculus and form ascendent and descendent tracts. • The meninges are membranes of connective tissue that protective structures of the Central nervous system with spaces between their.