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Miguel B. Sebastian Jr. M.D., D.P.P.S.
           Department of Physiology
                                OLFU
   The Human Ear
   Function of the muscles and ossicles
   Functions
    ◦ Protects the cochlea from damaging vibrations by
      excessively loud sounds
    ◦ Mask low frequency sounds in loud environments
    ◦ Decrease persons sensitivity to his or her own
      speech
    ◦ Latency – 40 to 80 milliseconds
    ◦ Contraction of tensor tympani and stapedius
      dampens the movement of ossicles and
      decreases the sensitivity of acoustic apparatus
    ◦ Reduces intensity of sound transmission by 30 –
      40 dB
   Impedance Matching Device (tympanic
    membrane and ossicles)
   Acoustic impedance higher in fluid-filled
    cochlea than in air
   Depends on the following
    ◦ Ratio of the surface area of large tympanic
      membrane to that of the smaller oval window
    ◦ Mechanical advantage of the lever system formed
      by the ossicle chain
   Eustachian tube – equalizes pressure
    differences between external ear and middle
    ear
   Infection: fluid collects in middle ear  E.T.
    blocked  pressure differences 
    pain, displacement of the Tympanic
    Membrane  rupture
   Sound
    ◦ Produced by compression and decompression
      waves that are transmitted in air or in other elastic
      media such as water
   Sound Frequency
    ◦ Measured by cycles per second – hertz (Hz)
    ◦ Travels more slowly than light
      Light – 300,000 km/sec (186,000 miles/sec)
      Sound – 0.331 – 0.334 km/sec (0.2 miles/sec) – at 20
       oC at sea level (↑ with temperature and altitude)
                      - 335 m/sec in air (Berne & Levy)
      Speed of sound: Solid > Liquid > Air
   Sound wave
    ◦ Expressed as Sound Pressure Level (SPL)
    ◦ Decibel (dB)
    ◦ SPL = 20 log P/Pr
               P= sound pressure
               Pr = reference pressure (0.0002 dyne/cm2)
                      - the absolute threshold for human
                             hearing at 1000 Hz
   Normal Human Ear
    ◦ Sensitive to pure tone with frequency of 20 to
      20,000 Hz
    ◦ >100 dB – damage the auditory apparatus
    ◦ >120 dB – pain and permanent damage

    * As people age, their threshold at high frequency
    rises thereby reduces the ability to hear such tone
    (presbycusis)
   Sound waves  cause T.M. to oscillate  Oscillations
    transmitted to the scala vestibuli  creates a pressure
    difference between the S.V. and S.T.  displaces the basilar
    membrane  stereocilia of the hair cells bend.

   Upward displacement bends the stereocilia toward the tallest
    cilium (away from the modiolus) depolarizes the haircells.
   Downward deflection – bends the stereocilia away -
    hyperpolarized
• apex is wider than the
  base
• tension is higher at
  the base than at the
  apex
• base vibrate at higher
  frequency than the
  apex (frequency
  analyzer)
• length of the fibers is
  greater at the apex than at
  the base
• fiber diameter is greater at
  the base than at the apex
• base -- shorter and
  wider
• apex – taller and slender
• high –frequency resonance
  (base), low frequency
  resonance (apex)
   Ossicular Conduction
    ◦ Main pathway for normal hearing
   Air Conduction
    ◦ Unimportant for normal hearing
    ◦ Mediated by vibration of round window
   Bone Conduction
    ◦ Involves skull bone
    ◦ Plays a role in transmission of extremely loud
      sounds
   Presence of one sound decreases an
    individual’s ability to hear other sounds
   Due to the relative and absolute
    refractoriness of previously stimulated
    auditory receptors and nerve fibers to other
    stimuli
   Brodmann’s area 22
    ◦ Concerned with the processing of auditory signals
      related to speech
    ◦ Right side – melody, pitch and sound intensity
   Planum Temporale
    ◦ Portion of posterior superior temporal gyrus
    ◦ Involved in language-related auditory processing
   Conductive Deafness
    ◦ Due to impaired sound transmission in external and
      middle ear
    ◦ Impacts all sound frequencies
    ◦ Causes:
        Plugging of the EAC with cerumen or foreign body
        Otitis externa and otitis media
        Perforation of eardrum
        osteosclerosis
   Sensorineural Deafness
    ◦ Due to loss of cochlear hair cells
    ◦ Problems with CN VIII
    ◦ Lesions within the Central Auditory Pathway
    ◦ Impairs the ability to hear certain pitches
      (permanent)
    ◦ Causes:
         Aminoglycosides
         Prolonged exposure to noise
         Tumors and vascular damage
   Audiometer
   Tuning Fork
Thanks!!!

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Functions of the Ear and Hearing Process

  • 1. Miguel B. Sebastian Jr. M.D., D.P.P.S. Department of Physiology OLFU
  • 2. The Human Ear
  • 3.
  • 4.
  • 5.
  • 6. Function of the muscles and ossicles  Functions ◦ Protects the cochlea from damaging vibrations by excessively loud sounds ◦ Mask low frequency sounds in loud environments ◦ Decrease persons sensitivity to his or her own speech ◦ Latency – 40 to 80 milliseconds ◦ Contraction of tensor tympani and stapedius dampens the movement of ossicles and decreases the sensitivity of acoustic apparatus ◦ Reduces intensity of sound transmission by 30 – 40 dB
  • 7. Impedance Matching Device (tympanic membrane and ossicles)  Acoustic impedance higher in fluid-filled cochlea than in air  Depends on the following ◦ Ratio of the surface area of large tympanic membrane to that of the smaller oval window ◦ Mechanical advantage of the lever system formed by the ossicle chain
  • 8. Eustachian tube – equalizes pressure differences between external ear and middle ear  Infection: fluid collects in middle ear  E.T. blocked  pressure differences  pain, displacement of the Tympanic Membrane  rupture
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14. Sound ◦ Produced by compression and decompression waves that are transmitted in air or in other elastic media such as water
  • 15. Sound Frequency ◦ Measured by cycles per second – hertz (Hz) ◦ Travels more slowly than light  Light – 300,000 km/sec (186,000 miles/sec)  Sound – 0.331 – 0.334 km/sec (0.2 miles/sec) – at 20 oC at sea level (↑ with temperature and altitude) - 335 m/sec in air (Berne & Levy)  Speed of sound: Solid > Liquid > Air
  • 16. Sound wave ◦ Expressed as Sound Pressure Level (SPL) ◦ Decibel (dB) ◦ SPL = 20 log P/Pr P= sound pressure Pr = reference pressure (0.0002 dyne/cm2) - the absolute threshold for human hearing at 1000 Hz
  • 17. Normal Human Ear ◦ Sensitive to pure tone with frequency of 20 to 20,000 Hz ◦ >100 dB – damage the auditory apparatus ◦ >120 dB – pain and permanent damage * As people age, their threshold at high frequency rises thereby reduces the ability to hear such tone (presbycusis)
  • 18.
  • 19.
  • 20. Sound waves  cause T.M. to oscillate  Oscillations transmitted to the scala vestibuli  creates a pressure difference between the S.V. and S.T.  displaces the basilar membrane  stereocilia of the hair cells bend.  Upward displacement bends the stereocilia toward the tallest cilium (away from the modiolus) depolarizes the haircells.  Downward deflection – bends the stereocilia away - hyperpolarized
  • 21.
  • 22. • apex is wider than the base • tension is higher at the base than at the apex • base vibrate at higher frequency than the apex (frequency analyzer)
  • 23. • length of the fibers is greater at the apex than at the base • fiber diameter is greater at the base than at the apex • base -- shorter and wider • apex – taller and slender • high –frequency resonance (base), low frequency resonance (apex)
  • 24.
  • 25. Ossicular Conduction ◦ Main pathway for normal hearing  Air Conduction ◦ Unimportant for normal hearing ◦ Mediated by vibration of round window  Bone Conduction ◦ Involves skull bone ◦ Plays a role in transmission of extremely loud sounds
  • 26. Presence of one sound decreases an individual’s ability to hear other sounds  Due to the relative and absolute refractoriness of previously stimulated auditory receptors and nerve fibers to other stimuli
  • 27. Brodmann’s area 22 ◦ Concerned with the processing of auditory signals related to speech ◦ Right side – melody, pitch and sound intensity  Planum Temporale ◦ Portion of posterior superior temporal gyrus ◦ Involved in language-related auditory processing
  • 28.
  • 29.
  • 30. Conductive Deafness ◦ Due to impaired sound transmission in external and middle ear ◦ Impacts all sound frequencies ◦ Causes:  Plugging of the EAC with cerumen or foreign body  Otitis externa and otitis media  Perforation of eardrum  osteosclerosis
  • 31. Sensorineural Deafness ◦ Due to loss of cochlear hair cells ◦ Problems with CN VIII ◦ Lesions within the Central Auditory Pathway ◦ Impairs the ability to hear certain pitches (permanent) ◦ Causes:  Aminoglycosides  Prolonged exposure to noise  Tumors and vascular damage
  • 32. Audiometer  Tuning Fork
  • 33.