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The Cytoskeleton
Shareeka Joana Ngilay
What is Cytoskeleton?
Cytoplasm contains a
complex network of
filaments and microtubules
which form a structural
framework known as
CYTOSKELETON.
Cells need (cyto) skeleton to:
*create shape
*change shape
*allow movement
Dynamic!
Cytoskeleton: The skeleton and muscle of a cell
Three main kinds of fibers make up
the CYTOSKELETON:
● MICROFILAMENT
● INTERMEDIATE FILAMENT
● MICROTUBULES
MICROFILAMENT
● Thinnest filament present
in the cytoskeleton in
cytoplasm of eukaryotic cell.
● Give the cell its shape
and enable cell movement
MICROFILAMENT
FUNCTIONS OF MICROFILAMENT
Microfilaments play a role in
structure, cell motility, and cell
division. Microfilaments are made
of actin, and thus are involved in
muscle contraction as well as cell
division.
INTERMEDIATE FILAMENTS
● Made of variety of proteins,
including keratin, desmin and
vimentin
● 8 to 12 nanometer
● Composed of two anti
parallel dimer
INTERMEDIATE FILAMENTS
FUNCTIONS OF INTERMEDIATE FILAMENT
● provide mechanical support for
the plasma membrane where it comes
into contact with other cells or with
the extracellular matrix
● intermediate filaments do not
participate in cell motility.
MICROTUBULES
● Microtubules, the thickest fibers, are
hollow rods about 25 microns in
diameter.
● Microtubule fibers are made up of
the globular protein, tubulin, and they
grow or shrink as more tubulin molecules
are added or removed.
MICROTUBULES
Microtubules participate in the
intracellular transport of organelles
and vesicles.
FUNCTIONS OF MICROTUBULES
Microtubules are the central structural
supports in cilia and flagella.
The locomotive appendages of cell
Cilia
● minute hairlike organelles, identical in
structure to flagella, that line the surfaces
of certaincells and beat in rhythmic waves,
providing locomotion to ciliate protozoan a
nd moving liquids along internal epithelial
tissue in animals.
CILIA
FLAGELLA
● A slender threadlike structure,
esp. a microscopic whiplike
appendage that enables many
protozoa, bacteria, spermatozoa,
etc., to swim.
FLAGELLA
FLAGELLA
Thank you

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Cytoskeleton