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BY Dr. Sateesh kumar 
Moderators: Dr.Raghuram 
Dr.Jaipal 
KMIO
 Introduction 
 Embryology 
 Gross Anatomy 
 Blood, Nervous 
supply 
 lymphatic drainage 
 Imaging Modalities 
Conclusion
 Is the longest part of 
alimentary canal 
 Extends from pylorus of stomach to 
 ileocecal junction 
 Length = 3 m in a living person 
& 6.5 m in a cadaver 
(loss of muscle tone) 
 Diameter = 4 cm in gastroduodenal jn 
& 2.5 cm at i-c junction. 
Small bowel represents 75% of the length 
& 90 % of mucosal surface of intestinal tract.
 Site :it occupies all 
abdominal regions except 
epigastic and 
hypochondriac 
region normally 
 Fixation :it is stabilized by 
mesentery 
 Mesentery = peritoneal 
fold attaching small 
intestine to posterior body 
wall
 Anatomical subdivisions : 
 a) Duodenum 
 b) Jejunum 
 c) Ileum 
 Duodenum = C-shaped tube 
which is attached to the 
Stomach. 
 Jejunum = is the coiled 
Midportion. 
 Ileum = the final 
section,which leads into the 
large intestine.
Embryology: 
 Duodenum: above and including ampulla of vater is 
developed from foregut. 
 Rest from midgut 
 Jejunum and ileum (except terminal portion) pre-arterial 
segment of midgut loop. 
 The terminal portion of the ileum is derived from the post-arterial 
segment proximal to the caecal bud. 
 Endoderm gives rise to mucosal lining of small bowel rest 
of the layers are derived from splanchanic laayer of lateral 
plate mesoderm.
Duodenum: 
 C-shaped tube 
 25 cm long & width 3.75-4 
cm 
 Joins stomach to jejunum 
 The first & shortest part of 
small intestine 
 The widest & most fixed part 
 Curves around the head of 
 pancreas 
 Begins at pylorus on right 
side & ends at 
duodenojejunal junction on 
left side 
 Partially retroperitoneal
 Duodenum is divided into 
four 
 parts : 
 a) First (superior) part 
 b) Second (descending) part 
 c) Third (horizontal) part 
 d) Forth (ascending) part 
 First part of duodenum 
 It is 5 cm long 
 Lies anterolateral to body of 
L1 vertebrae 
 Most movable part
Duodenum 
 Second part: 
 It is 8 to 10 cm long 
 Descends along right sides 
of L1 through L3 vertebrae 
 Third part : 
 It is 10 cm long 
 Crosses L3 vertebra 
 Fourth part of 
duodenum Ascending 
 It is 2.5 cm long 
 Begins at left of L3 & rises 
superiorly as far as superior 
border of L2 and continues 
with jejunum
ANATOMICAL RELATIONS 
 FIRST PART- 
 PERITONEAL RELATIONS: 
2.5cms movable and 
attached to lesser and greater 
omentum. Next 2.5cms is 
fixed and retroperitoneal. 
 VISCERAL RELATIONS: 
 Anteriorly: Quadrate lobe of 
liver andGB 
 Posteriorly: Gastroduodenal 
A, bile duct and PV 
 Superiorly: floor of Epiploic 
foramen. 
 Inferiorly: Head and neck of 
pancreas.
SECOND PART- 
 PERITONEAL RELATIONS: 
retroperitoneal & fixed. 
 VISCERAL RELATIONS: 
 Anteriorly: Rt lobe of liver, 
transverse colon 
root of transverse mesocolon 
Posteriorly: Anterior surface 
of rt kidney, rt renal vessels, 
rt edge of IVC,rt psoas 
 Medially: Head of pancreas 
and bile duct. 
 Laterally: Rt colic flexure
THIRD PART- 
 PERITONEAL 
RELATIONS: 
retroperitoneal & fixed. 
 VISCERAL RELATIONS: 
 Anteriorly: Superior 
mesenteric vessels 
 Posteriorly: Rt ureter, rt 
psoas major, rt testicular 
or ovarian vessels, IVC 
abdominal aorta. 
 Superiorly: Head of 
pancreas. 
 Inferiorly: Coils of 
jejunum.
FOURTH PART- 
 PERITONEAL RELATIONS: 
retro-peritoneal & mobile. 
 VISCERAL RELATIONS: 
 Anteriorly: Transverse colon & 
mesocolon, lesser sac & 
stomach. 
 Posteriorly: Lt sympathetic 
chain, lt psoas, lt renal vessels, lt 
testicular veins & inferior 
mesenteric vein. 
 To the right: attachment of 
upper part of root of mesentry. 
 To the left: Left kidney & ureter. 
 Superiorly: Body of pancreas.
Ligament of trietz 
 Suspensory ligament of duodenum 
 Fibromuscular band arising from rt crus of diaphragm 
close to oesophageal opening and attaches to 
posterior surface of D-J Flexure 
 Upper 1/3- striated muscle 
 Middle 1/3- elastic tissue 
 Lower 1/3- smooth muscle
Interior of Duodenum
 smooth muscle lining of 1st 
part of duodenum is 
longitudinal 
 plicae circularis 
 (circular folds) of 2nd part 
of duodenum 
 Major duodenal papilla is a 
small rounded elevation at 
site where bile duct & main 
pancreatic duct pierce 
medial wall of 2nd part of 
duodenum
JEJUNUM & ILEUM 
 Jejunum begins at 
duodenojejunal flexure 
(L2) & ileum ends at 
ileocecalJunction. 
 Jejunum & ileum = 6 to 7 
m 
long (jejunum 2/5, ileum 
3/5) 
 Coils of jejunum & ileum 
are suspended by 
mesentery from posterior 
abdominal wall & freely 
movable. 
 Most jejunum lies in 
leftupper quadrant & most 
ileum lies in right lower 
quadrant
 Wall of small intestine is made of the following layers : 
 a) Serosa coat 
 b) Muscular coat 
 c) Submucosa coat 
 d) Mucosa coat 
 Serosa: made of peritoneum 
 Muscularis: made of smooth muscle fibers arranged in 
outer longitudinal & inner circular layers 
 Submucosa : contains loose CT & large venous plexuses 
(submucosa of duodenum contains duodenal or Brunner’s 
glands) 
 Mucosa composed of a layer of epithelium, lamina propria 
& muscularis mucosa (Plicae circulares numerous in 
jejunum, Peyer’spatches present in ileum)
 Intestinal crypt epithelium 
 Secretory cells that 
produce intestinal juice 
 Enteroendocrine cells 
 Intraepithelial 
lymphocytes (IELs): 
Release cytokines that kill 
infected cells 
 Paneth cells:Secrete 
antimicrobial agents 
(defensins and lysozyme) 
 Stem cells
 Duodenum 
 Arterial supply: Upper half 
is supplied by superior 
pancreaticoduodenal(gatro-duodenal) 
 Lower half is supplied by 
inferior 
pancreaticoduodenal(SMA) 
 Venous drainage 
 Superior 
pancreaticoduodenal vein 
drains into portal vein 
 inferior vein joins superior 
mesenteric vein.
Blood supply: 
 Ileum and Jejunum 
Arterial supply: Branches of superior mesenteric artery 
 Intestinal branches arise from left side of the artery & run 
in mesentery to reach the gut (gastrointestinal tract) 
 They anastomose with one another to form as series of 
arcades 
 Lowest part of ileum is supplied by ileocolic artery 
 Venous drainage 
 Veins correspond to branches of superior mesenteric artery 
& drain into superior mesentery vein
Lymphatic drainage: 
 Duodenum: 
 Lymph vessels follows arteries & drain upward via 
pancreaticoduodenal nodes to gastroduodenal nodes 
& then to celiac nodes . 
 Downward via pancreaticoduodenal nodes to superior 
mesenteric nodes around origin of superior mesentery 
artery 
 Jejunum & Ileum: Lymph vessels pass through many 
intermediate mesenteric nodes & finally reach 
superior mesenteric nodes (situated around origin of 
mesenteric artery)
Nerve Supply: 
 Duodenum: 
 Nerves are derived from sympathetic (T6-T9)& 
parasympathetic (vagus) nerves from celiac & superior 
mesenteric plexuses 
 Jejunum & Ileum: 
 Nerves are derived from sympathetic & 
parasympathetic (vagus) nerves from superior 
mesenteric plexus
Mesentary: 
 Broad fan shaped fold of peritoneum that suspends 
jejunum and ileum from posterior abdominal wall 
 Conveys nutrition and innervation 
 Consists of 2 layers derived from greater sac 
 Root- 15cms long extends from left side of L1 vertebrae 
at duodenojejunal junction to Rt Sacro-iliac joint at 
ileo-caecal junction. 
 Free border separates to enclose jejunum n ileum
Need for imaging 
• Small bowel diseases presents with non specific 
symptoms. 
• Small bowel represents 75% of the length & 90 % of 
mucosal surface of intestinal tract. 
• Diagnostic tests which can provide documentation of 
structural abnormality or normality. 
• Limited role of enteroscopy of small bowel has 
retained barium examination of small bowel as 
primary investigation for its mucosa.
Plain abdominal Radiograph: 
Most commom indication suspected bowel obstruction 
/Perforation . 
Views 
Supine 
Erect 
Lateral dorsal decubitus 
Antero-posterior or posteroanterior left lat decubitus 
Erect PA chest
35*43 24*30
NORMAL GAS PATTERN 
 Stomach 
- always 
 Small bowel 
- 2 or 3 loops of non-distended bowel 
- normal diameter = 2.5-3 cm 
 Larger bowel 
- in rectum or sigmoid colon - always
 Fluid levels: 
 3 to 5 fluid levels < 2.5 cm in length may be seen 
particularly in the right lower quadrant. 
More than 2 fluid levels in dilated small bowel 
more than 2.5 cm caliber are abnormal and 
usually indicate paralytic ileus or intestinal 
obstruction
NORMAL FLUID LEVELS 
 Stomach 
- always (except supine film) 
 Small bowel 
- 2 or 3 levels possible 
 Large bowel 
- none normally
Usg-small bowel: 
 Both standard (2.5–6 MHz) abdominal convex probe 
and high resolution (7.5–14 Mhz) probe are used 
 All parts of small bowel—duodenum, jejunum and 
ileum are accessible to TUS examination. 
 Isosmotic polyethylene glycol (PEG) solution 1000 mL 
is required for small intestine contrast sonography 
(SICUS) enteroclysis or hydrosonography of SB.
GUT SIGNATURE 
 The sonographic layers 
appear alternately echogenic 
and hypoechoic 
 the first, third, and fifth 
layers are echogenic, 
 the second and fourth layers 
are hypoechoic. 
 muscular components of the 
gut wall—the muscularis 
mucosa and the muscularis 
propria—constitute the 
hypoechoic layers on 
 sonography
 The quality of the scan and the resolution of the transducer 
determine the degree of layer differentiation 
 Normal intestinal wall thickness is generally ≤ 3 mm (using mild 
compression) ranging from small diameters in the jejunum, 
ileum 
 5mm is considered upper limit for non-distended bowel 
 Physiological contraction of the intestine leading to a thickened 
wall segment may cause misinterpretation, therefore bowel 
motions have to be taken into account before measurements are 
performed 
 In addition to wall thickening, echomorphology (integrity of 
wall architecture) and surrounding structures have also to be 
considered in the interpretation of the intestinal wall diameter.
 Normal small bowel: 
Transverse view of pars 
horizontalis duodeni 
between aorta and SMA.
Normal small bowel: Longitudinal view of jejunum in left mesogastrium—with numerous 
valvulae conniventes. 
Longitudinal section of terminal ileum (TI) in the left iliac fossa
Valvulae conniventes (plicae circulares) of the small bowel. These are more easily 
seen when there is fluid in the lumen of the bowel
 Sonographic appearance 
of an inflamed colon 
segment in Crohn’s 
disease. Characteristic 
appearance: thickened 
wall diameter (almost 1 
cm), partial loss of wall 
stratification, prominent 
submucosal layer, 
narrowed lumen and 
mesenteric fat 
hypertrophy.
 Small Intestine Contrast Ultrasonography 
(SICUS) or Hydrosonography. TUS with using oral 
contrast solution (iso-osmolar nonabsorbable polyethylene glycol solution 
(PEG). The amount of PEG solution used in different studies varies between 
200 and 2000 mL. 
 On average, the entire small intestine could be visualized on ultrasonography 
by about 45 min after the ingestion of 600 mL or less of contrast solution 
without any side effects . 
 SICUS improves TUS resolution by separating of SB walls and eliminating 
bowel gas. 
 Compared with conventional sonography luminal filling can improve 
visualisation of bowel walls and fold pattern but extends time of examination 
(vary between 30–40 min). 
 In the study of Pallotta et al. SICUS is proved superior to that of standard TUS 
in detecting the presence, number, extension, and sites of small bowel lesion
 Color Flow (Power) Doppler—CFD. It is used to estimate 
presence, density or absence of vascular signals in 
thickened segments of bowel wall, in intraluminal or 
extraluminal pathological structures and for imaging flow 
in big abdominal vessels—SMA, coeliac trunk, portal vein. 
CFD is part of standard abdominal and bowel sonography. 
 2cm after the SMA branches off from the aorta, and as it 
runs parallel to the aorta 
 Triplex Scanning or Color Assisted Duplex Scanning (TUS 
+ CFD + PWD). Enables evaluation of SMA/CA flow and 
intramural flow in thickened bowel segments
 Readily detected color 
 Doppler flow and a 
resistive index less than 
0.6 wereconsistent with 
inflammation 
Cross-sectional images of ileum proximal to an obstructing lesion. The lumen is 
distended with fluid. The wall is slightly thick. ON Color Doppler image 
marked hyperemia of the gut wall as a reflection of its inflammation
 Non-invasiveness and lack of radiation, makes TUS is a 
relatively good alternative to CT or MRI enterography, 
particularly in young patients and pregnant women. 
 In the duodenum and terminal ileum, TUS can detect 
the most of benign and malignant tumors. 
 TUS is easily available , noninvasive, and low-cost 
diagnostic procedure. 
 significant limitations (obesity, meteorism) 
 In the hands of experienced examiner offers reliable 
tool for SB diseases examination.
Barium Techniques 
 Barium studies classified into indirect and direct 
techniques. 
 Indirect techniques examine the SI with barium that 
has passed through the upper GIT or colon before 
entering the SI and include the 
 follow through examination/dedicated follow throgh 
 complete reflux examination (retrograde exam.) 
 peroral pneumocolon examination of the ileocaecal 
region
 Direct technique 
 Enteroclysis (small bowel enema) involve introducing 
barium or other contrast agents directly through a tube 
into the distal duodenum, proximal jejunum, or the 
more distal SI
Indications Contraidications 
 Patients who have low 
suspicion of small bowel 
disease – abdominal pain 
and diarrhea 
 Suspected complete or 
near complete small 
bowel obstruction 
 Crohn’s diease 
 Patients eho refuse for 
placement of nasojejunal 
tube/bilbao catheter 
 Colonic obstruction 
 Suspected perforation 
 Paralytic ileus
Contrast media 
 Medium density barium suspension (50-60%w/v) 
 Suspending agent to prevent flocculation and 
maintain stability 
 High density barium(200-250%) may produce an 
appearance of fold thickening and clumping of small 
bowel 
 Acid Baso4 suspension may produce spasm,enlarged 
folds and dilatation of duodenum & jejunum 
 Alkaline Baso4 suspension improves coating of 
valvulae and improves diagnostic accuracy
 Entrobar is a raspberry flavored barium sulfate suspension. It is a 
contrast medium developed for use in enteroclysis and follow-through 
x-ray examinations of the small intestine. 
 The product contains 50% w/v barium sulfate USP, suspending 
and dispersing agents, simethicone, citric acid, potassium 
sorbate, flavoring, sodium citrate, saccharin sodium and water. 
Barium sulfate has the empirical formula of BaSO4. 
 Barium sulfate is an insoluble material which, because of its 
density, provides a positive contrast during x-ray examination. 
Barium sulfate is an inert radiopaque material which is not 
absorbed or metabolized and is eliminated intact from the body 
in a manner similar to other non-absorbed inorganic materials. 
Excretion rate is a function of gastrointestinal transit time.
Preparation 
 Purgative-Dulcolax 2tab HS (not in suspected 
obstruction,acute crohns exacerbation,ileostomy) 
 Low roughage high fluid intake diet 48hrs prior 
 No food/fluid should be taken for 12hrs before 
investigation 
 No antispasmodics codeine tranquilizers 24-48hrs 
prior
Barium follow-through examination 
 This is performed following a barium meal 
examination of the esophagus, stomach and 
duodenum 
 150ml 250%w/v—200ml 20-25%--250ml40-45% 
 As the barium column progresses through the small 
intestine large radiographs of the abdomen are taken 
at intervals 
 First one is taken with the patient supine about 15 
minutes after the barium meal and shows the proximal 
jejunum
 The remaining radiographs are normally taken at half 
hourly intervals with the patient prone. 
 When the barium column reaches the caecum spot 
views of the terminal ileum are taken 
 It takes from 2 to 6 hours for the head of the barium 
column to reach the caecum
Dedicated small bowel follow 
through 
 Single contrast technique 
 Barium 50-60% 600-900ml 
 Drink as rapidly as possible 
 To right lateral position 15-20mins 
 Then prone filming done every 15-20min until 
ileocaecal junction opacification noted 
 To demonstrate ileocaecal junction supine right is best 
as ileum enters caecum posteromedially 
 Always empty the bladderprior to these spot films
Single contrast technique 
Positioning Purpose 
First Right side down 
dependent 
To aid gastric 
emptying 
Second Prone To separate 
bowel loops 
Third Right side up To visualize IC 
junction
 Periodic fluoroscopic examination and compression 
spot films are recommended 
 4 spot films for ileocaecal junction should be taken 
with variable degree of compression 
 Compression over bowel loops to avoid overlap thereby 
prevents efffacemen of mucosa and small lesions may 
not be missed 
 The abnormality must be shown in 2 spot films taken 
at different times to confirm persistence of lesion
 Overlap of contrast filled bowel loops in pelvis 
 Overcome by 
 Table head down 
 30 degree caudal angled view of pelvis 
 Emptying urinary bladder prior to filming ileal loops 
 Peristalisis can be increased by metoclopromide 
neostigmine cck glucagon 
 20-40ml sodium/meglumine ditriazoate or gastrograffin to 
barium increases transit time 
 Cold water- inc palatibility speeds gastric emptying
Interpretation 
Jejunum Ileum 
Constitutes proximal 
2/5ths of small intestine 
3/5ths 
Position Upper left and 
periumblical region 
Lower right hypogastric 
and pelvic region 
Max. diameter 4 cm 3 cm 
Number of folds 4-7 per cm 3-5 per cm 
Pattern Feathery mucosa Less feathery or maybe 
absent 
Fold thickness 1.5-2mm bowel wall depth 1-1.5mm
BA Meal follow through:
The pattern of the mucosal lining of the first part of the duodenum is different 
from the other parts. longitudinal pattern of the mucosa of the first part of the 
duodenum forming what is known as the duodenal cap This pattern is very 
similar to that of thepylorus of the stomach This pattern changes to a 
more flecked appearence in the distal duodenum
Reflux examination 
 Barium and air refluxed through the ileocaecal valve during 
a barium enema examination give good views the terminal 
ileum. Replaced by enteroclysis 
 The radiographs should be studied carefully and spot views 
of the distal ileum is taken if necessary 
 All of the small intestine can be examined by refluxing 
barium from the colon into the terminal ileum – the 
complete reflux examination
doublecontrast barium enema examination 
(with reflux 
into terminal ileum) shows carcinoid tumor 
in terminal ileum 
Doublecontrast barium enema 
examination (with reflux 
into terminal ileum) shows lipoma 
as smooth, ovoid, submucosal 
mass in distal ileum
Peroral Pneumocolon examination 
 Excellent view of the terminal ileum and caecum can 
be obtained by giving barium orally and when the 
head of the barium column has reached the ascending 
colon introducing air per rectum and refluxed in to 
distal ileum 
 Glucagon can be used to relax ileocaecal valve 
 This procedure shows Crohn’s disease and carcinoma 
of the caecum particularly well
Per oral pneumocolon 
examination 
Indications contraindicatns 
 Terminal ileum porly 
visualized on routine 
compresion spot films . 
 Clinical suspicon of Crohn 
disease with normal 
apearance of terminal ileum 
 abnormal apearance of 
terminal ileum on routine 
compresion spot films 
 history ileocolic 
anastomosis. 
 Recent colonic or rectal 
biopsy
Advantages Disadvantages 
 Easily performed 
 No catheterisation 
 Physiologic transit time 
can be assessed 
 Overlapping of barium 
filled bowel loops in 
pelvis 
 Poor distension 
 Partial or intermittent 
bowel obstruction 
 Operator dependant 
 Time consuming
Complicaions 
 Leakage of barium form unsuspected perforation 
 Aspiration 
 Impacted barium converts partial obstruction in to 
complete obstrction 
 Barium appendicitis impaction at appx
ENTEROCLYSIS (small bowel 
enema) 
INDICATIONS 
 Partial small bowel obstruction 
 Crohn’s ds 
 Suspected meckel’s diverticulum 
 Malabsorption 
 Neoplasms (cancers) 
 Occult GI bleeding 
 Equivocal BMFT but strong clinical suspicion
CI 
 Complete colonic obstruction 
 Duodenal obstruction n GJ 
 Suspected perforation 
 Massive dilatation of small bowel 
 Paralytic ileus
Normal follow through 
Enteroclysis - normal small 
bowel mucosa 
23
catheter 
 1)bilbao dotter tube – 
22F polyethylene,150cm 
 2)silk tube 
 3)Maglinte balloon 
enteroclysis catheter
Bilbao dotter tube 
 Bilbao Dotter tube is (22 F 
polyethylene tube which is 
150 cms long with a guide 
wire which is 5 cms shorter 
than the tube, with 
multiple side holes which 
are 8 in number without an 
end hole 
 guide wire is teflon coated 
to reduce friction). 
 Latest modified 
catheters(10F-14F) 
 children 7F caths are used
Maglintos Balloon enteroclysis 
catheter 
 Modification of the 1 4 French Bilbao duodenal tube 
 Made of radiopaque polyvinyl chloride 
 1 60 cm - length, inner diameter -0.1 1 0 mm and an outer diameter of 0.1 70 
mm (1 3 French). 
 Six side holes measuring 0.70 inches (1 8 mm) in diameter are located distal to 
the latex balloon. 
 This closed-end catheter has a weighted tip 5 cm distal to the balloon, attached 
proximal to the last row of side holes . 
 Balloon lumen measures 0.030 inches (0.76 mm) and is provided with a one-way 
check valve attached adjacent to the open end of the catheter. 
 About 12-15 ml of air gauged fluoroscopically is injected once the 
 catheter tip is in the desired position. 
 A 1 80-cm-long, Teflon-coated, stainless-steel, braided torque guide wire 
 0.065 inches (1 .7 mm) in outer diameter is provided with a straight tip to act as 
a stiffener and angled tip fordirectional or torque control.
Advantages 
 material does not have to be held up by normal pyloric 
activity 
 Quicker 
 increase in distention of lumen 
 Disease that reduce this distention –easily identified
Disadvantages 
 placement of 
enteroclysis catheter 
 higher doses of 
radiation
Contrast medium 
 Single – 20% w/v suspension of micropulverised barium 
with added suspending agent in alkaline medium 
 Double – high density low viscosity 200 – 250% 
Ba + methylcellulose 
Ba + air – air double contrast EC 
adv : mucosal detail superior to any other examination 
10gms of carboxymethylcellulose added to 2litres of warm 
water. Refrigerate mixture overnite and shake well before 
use
Why methylcellulose? 
 Commonly used as bulk laxative and suspending agent 
 Non irritating to bowel mucosal lining 
 Unable to be absorbed 
 No toxic effects on body 
 Natural tendancy to retain water in lumen promotes 
peristalisis and prevents luminal collapse. 
 Propels barium to distal ileum and colon 
 Low diffusivity with compatiable ba suspension and thus 
preserves an interface between dense barium coating of 
mucosa and luminal water density 
 Promotes evaccuation by laxative effect
Patient preparation 
 Non-residue liquid diet(a day prior) 
 NPO(after midnight) 
 Medication – reduce motility (a day prior) 
 Laxative – magnesium citrate/bisacodyl(CI-partial 
obst) 
 Asc col and terminal ileum clear from stool 
 Drugs – 
 antich, ganglion blocking – diltn-mimic sprue 
 Narcotics 
 For infants, 4 hrs fasting ,sedation.
Contrast dose : 
Age dose 
3-5 mnths- 200ml 
5-8 mnths- 300ml 
8-11 mnths- 400ml 
1-3 yrs- 500ml 
Children 
And adults- 1-1.5 litres
Inflation of baloon 
 15 to 20 ml 
 Beyond lig of Treitz 
 Reflux into stomach – 
distention, nausea
 Infusion of Barium 70 to 75 ccs/min 
 Infusion of methyl cellulose 70 to 120 ccs/min 
 important that ba advance in an uninterrupted column 
and w/o causing focal distention of lumen.
Technique: 
 Preliminary plain radiographs of the abdomen: 
To determine wether the patient is adequately 
prepared and to exclude the presence of barium 
from previous examinations. 
Free intraperitoneal air, displacement of bowel loops 
by mass, calcification and abnormality of bowel 
loops other than distension.
Procedure: 
 Patient sits upright on a chair placed against the wall so not 
to move away from the advanced tube. Alternatively, in a 
patient who cannot sit up, the tube can be placed with the 
patient supine or right lateral on the fluoroscopy table. 
 2-3 cc 2% xylocaine jelly is intorducd into the nostril 
through which the tube to be placed after ensuring no 
nasal blockage, with patients neck hyperextended. 
 The Bilbao-dotter tube without the guide wire is inserted 
through one of the nostrils and advanced with the 
swallowing action of the patient till the tip reaches 
stomach. 
 About 5-7 cms of the tube is passed in stomach and then 
neck is flexed. 
 Guide wire may be used to stiffen the tube to assist 
advancement through the esophagus into the stomach.
 Further it is advanced through the antrum into pyloric 
canal, now with guidewire 5cms proximal to tube tip, 
the tube is advanced till the tube enters duodenal cap, 
which may be facilitated by turning the patient supine 
with right side up so that the location of pyloric canal 
and duodenal cap can be seen outlined by air. 
 With further advancement the tube tip is placed at the 
duodenojejunal flexure with tip of guide wire in 
pyloric canal. 
 Finally the tube tip should be 4-5 cms distal to the 
ligament of treitz. Such a placement prevents reflux of 
barium and CMC into proximal parts of duodenum.
If stomach is collapsed or has very little gas, injectin 
100-150 ml of air will help the above manipulation. 
If stomach is overdistended with gas, aspirate out air 
to reduce distension 
If residual fluid in stomach,should be aspirated 
prior to manipulation 
While advancing the tube it will tend to hold up at 
the following places due to acute angulation of the 
intestine, junction of 1st- 2nd part 
duodenum;junction of 2nd-3rd parts of 
duodenum;duodenojejunal flexure
Problems: 
 Prolonged examination time: it is due to improper flow 
rates. Too high infusion rates should not be used. To 
restore peristalisis , inj.metoclopromide 10 mg IV is useful 
 Incomplete distension of small bowel: due to slow infusion 
rates, or due to excessive dose or response of 
metoclopromide. Increasing the rate of flow of contrast 
will solve the problem 
 Prolapse of small bowel into pelvis: few loops may dip into 
the pelvis, angled compression allows lifting of pelvic 
segments . If caecum obscures pelvic ileum, patient is 
turned prone and the table is tilted head down. This allows 
caecum to empty and terminal ileum becomes visible. 
 Fecal material in terminal ileum: due to incompetent 
ileocaecal valve or in patients who are chronic laxative 
users, infusion of adequate amount of methylcellulose will 
push debris into the colon
 Reflux into the duodenum and stomach: this is due to 
too fast infusion rate or small bowel obstruction. 
Incidence can be reduced by the use of ballon 
enteroclysis catheter. In patients with obstruction, 
preliminary decompression of stomach and proximal 
jejunum decreases reflux.
 Single contrast enteroclysis: 
This is performed in patient with a high grade partial 
small bowel obstruction. 
Barium suspension 20%w/v is injected at the rate of 75- 
120 ml/min 
An average of 1-1.5 lts of barium suspension in injected 
without any interruption 
Average time taken to reach the ileo-caecal junction is 
about 15 mins. 
Interrupted fluoroscopy is used to follow the head of the 
barium column 
Stenotic lesions are best identifiable at the head of the 
column
 Filming: 
One film for the jejunal loops, another film is taken for 
the entire small bowel. 
Spot films are taken with or without compression where 
ever necessary 
Spots of the ileocecal junction are done 
All filming is done with high kVp technique(120-140 kV)
 Double contrast enteroclysis: 
150-500 ml barium suspension(200-250% w/v) is 
injected at a rate of 80-100 ml/min, till the proximal 
ileum is reached. 
After this , 0.5 %suspension of CMC is injected at a rate 
of 75-120ml/min. 
Ileocaecal spot film should be taken initially when the 
barium column reaches the IC junction and again when 
the IC junction is in double contrast.
 Filming: 
Upper abdomen when jejunum is seen in double 
contrast 
Full abdomen when entire small bowel is in double 
contrast 
Ileocaecal junction spots in single and double contrast 
filming has to be completed within 20-25 mins for good 
double contrast effect 
Erect films donot give any additional information of 
small bowel study
Small bowel enema Small bowel follow 
through
Normal enteroclysis demonstrating catheter in first jejunal loop and well 
distended jejunum and proximal ileum with normal pattern of valvulae 
conniventes
Normal small bowel: 
 Fold shape: The folds are less pronounced or possible absent in the 
ileum. The folds run fairly straight and parallel, joining the bowel wall 
in the form of rounded corners. At times in the ileum, the folds may 
crowd together on the concave side of a bowel loop, creating a 
triangular fold pattern.
 Fold thickness: The folds are normally 1.8 mm thick in the jejunum, 
and 1.5 mm thick in the ileum. When the thickness exceeds 2.5 mm in 
the jejunum or 2.0 in the ileum, it is considered a pathologic finding.
 Number of folds: 4 to 7 folds per inch are normal for the 
proximal jejunum and 2 to 5 folds per inch is normal for the 
distal ileum
 Fold Height. The height of the folds is 3 to 7 mm in the jejunum and 
1.5 to 3.5 mm in the ileum. the height of the folds may vary 
considerably within the same segment of the bowel, thus the 
visualization of the entire segment for the height of the folds is must
 Lumen Diameter: There is a gradual decrease in lumen diameter from 
the jejunum into the ileum. The upper jejunum averages from 3.0 cm to 
4.0 cm, 2.5 cm to 3.5 in the lower jejunum, and 2.0 cm to 2.8 cm in the 
ileum. Abnormal diameters are anything that exceeds 4.5 cm in the 
upper jejunum, 4.0 cm in the distal jejunum, and 3.0 in the ileum.
Wall Thickness: When two adjacent loops are 
found to be parallel over a distance of at least 4 cm, 
with abdominal compression, the distance 
between the two represents the combined wall 
thickness. Half of this measurement is the 
thickness of a single loop. The wall thickness is the 
same throughout the small bowel. A wall thickness 
greater than 4 mm is considered abnormal.
Air double contrast enteroclysis: 
150-200ml Barium @ 60ml/min 
Intermittent fluoroscopy to visualise barium reaching 
terminal ileum. 
Inject 200ml of air @ 100ml/min initially 
A total of 600-1000ml air is necessary 
Antispasmodic iv/im when air reaches distal ileum 
Mucosal details superior 
Minimal narrowing is missed as air passes through 
Uncomfortable for patient
Comparision: 
 Methylcellulose DC 
enteroclysis 
1.Less information 
2.Simple procedure 
3.Less time(20-30 mins) 
 Air double contrast 
enteroclysis 
More clear detail 
Operator dependent 
Relatively longer time
ADVANTAGES OF ENTEROCLYSIS 
 Contrast material is administered at a desired rate and 
not influenced action of pyloric sphincter 
 Direct infusion at a rate that produces hypotonia, 
completely dilates the small intestine and therefore 
the fold patterns and mucosal abnormality can be 
easily assessed. 
 Because the distensibility if bowel lumen is challenged 
by enteroclysis, the bowel proximal to stenosis dilates 
thus facilitating recognition of even a minimal 
narrowing.
 Sinuses and fistulous tracts can be demonstrated 
by enteroclysis 
 Can be completed in less time 
 Enteroclysis tube may be left in place in patients 
with obstruction to achieve better decompression 
 Enteroclysis permits better delineation of the 
small bowel than that achieved by BMFT, 
segmentation and flocculation can be avoided.
Disadvantages 
Placement of the nasoenteric tube causes discomfort 
which can be minimised by sedation 
Extrapyramidal symptoms of metaclopramide can be 
made to subside by giving atropine or benadryl 
Nausea and vomiting due to inadequate tube 
placement proximal to ligament of treitz. 
Treatment: aspiration of contents by withdrawing 
the tube into the stomach 
Diarrhoea if large amount of fluid is given
 Rapid colonic emptying 
 Use of barium as primary contrast 
 Operator dependent 
 Failure to depict extraintestinal changes 
After care: 
The patient should be warned that diarrhoea may occur as a 
result of the large volume of fluid given 
Complications: 
Aspiration 
Perforation of bowel
Enterography vs Enteroclysis 
 Oral contrast  Enteral catheter 
 Better distension
CT Enterography 
 non-invasive technique for diagnosis of small bowel 
disorders. 
 Advantages 
 evaluates the entire thickness of the bowel wall 
 offers information about the surrounding mesentery 
the mesenteric vasculature and the perienteric fat 
 useful in the assessment of the solid organs and 
provides global overview of the abdomen
 non-invasive technique for diagnosis of small bowel 
disorders. 
 Adequate luminal distension is necessary as collapsed 
bowel loops may mimic pathology. CT enterography 
utilizes two types of contrast: 
 neutral oral contrast agents 
 these have attenuation similar to that of water e.g. water, PEG 
electrolyte solution, methyl cellulose 
 intravenous contrast is used with neutral agents 
 these agents allow better assessment of mucosal 
enhancement, mural thickness as well as mesenteric 
vasculature, this is important especially in the evaluation 
of Crohn's disease
 positive contrast agents 
 such as a dilute (1%) barium solutions 
 they are not routinely used in CT enterogrpahy 
 pathologic mural enhancement and intestinal 
hemorrhage are obscured by positive contrast agents 
 mainly used to detect lower grades of small bowel 
obstruction and internal fistula
procedure 
 Abstain from all food and drink 4-6 hours before the exam. 
 Patients drink about 1.5- 2 L of oral contrast over 40-60 
minutes. 
 Administration of intravenous contrast injection at a rate 4 
ml/sec. 
 CT scanning is ideally performed on a multi-detector 
computed tomography (MDCT) scanner about 45-65 
seconds after contrast material injection in a single 
(venous) phase or dual (arterial & venous) phases for the 
evaluation of mesenteric vasculature or GI tract bleeding. 
 Data interpretation with the use of axial and coronal 
reformatted images for proper evaluati
MR Enterography 
 Technique 
 patients should abstain from all food and drinks for 4-6 h 
prior to the study 
 patients drink about 1-1.5 L of a 2.5% mannitol solution at 
regular intervals over a period of approximately 40 min 
prior to the study 
 this solution acts as a hyperosmolar agent which draw fluid 
into the bowel & (biphasic) appears as low signal intensity on 
T1-weighted images and high signal intensity on T2-weighted 
images 
 scanning is ideally performed on a 1.5-T MRI scanner, using 
a phased array surface coil, either in the supine or prone 
position
MR ENTEROGRAPHY 
 MR protocol 
 comprehensive MR examination of the small bowel usually 
requires axial and coronal both T1 and T2 weighted images 
 high-resolution ultra-fast sequences such as true fast 
imaging with steady-state precession (true FISP) and 
HASTE sequences with and without fat suppression are 
usually used 
 fat-suppressed three-dimensional (3D) T1-weighted 
breath-hold gradient-echo images of the abdomen and 
pelvis before and after intravenous gadolinium-based 
contrast material administration
CT Enteroclysis 
 Computed tomographic (CT) enteroclysis is a hybrid 
technique that combines the methods of fluoroscopic 
intubation-infusion small-bowel examinations with that of 
abdominal CT 
 CT enteroclysis can be performed by using positive enteral 
contrast material without intravenous contrast material 
and neutral enteral contrast material with intravenous 
contrast material. 
 CT enteroclysis has been shown to be superior to other 
imaging tests such as peroral small-bowel examinations, 
conventional CT, and barium enteroclysis, except in the 
demonstration of early apthous ulcers of Crohn disease.
Technique: 
 Patient positioning: 
Head first, supine with arms extended above the 
level of head. 
 Topogram position/ landmark: 
Anteroposterior ; level of nipples to 3 cms below the 
inferior border of the symphysis pubis 
 Mode of scanning: helical with single breath hold 
technique.
 Scan orientation: craniocaudal 
Starting location- 1cm above the highest point of the dome 
of diaphragm 
End location- base of the bladder. 
 Gantry tilt-nil 
 Field of view-just fitting the abdominal wall 
 Contrast administration- intravenous monphasic and 
enteral via the nasoenteral tube 
 Enteric contrast:paraffin solution or polymethyl cellulose at 
a rate of 40-50 ml/ min 
 IV contrast-60-100 ml
 Rate of contrast injection:2-3ml/sec 
 Scan delay-40-50 sec 
 Slice thickness in reconstruction-3-5 mm 
 Slice interval in reconstruction-1.5-2.5mm 
 Reconstruction algorithm- medium smooth 
 3D reconstructions-MPR,MIP,VRT
 Patient is kept on overnight fasting before the 
examination. 
 Antigas and cathartics are given for bowel cleansing 
 Lots of fluids are prescribed to counteract the cathartic 
effects of the study( when high osmotic substance like 
mannitol/paraffin/polymethylcellulose are used). 
 The enteral contrast material is administered via the 
nasoenteric tube with its tip placed at the 
duodenojejunal flexure.
 CT enteroclysis utilises mainly two types of contrast : 
 neutral contrast media 
 these have attenuation similar to that of water e.g. water, 
methyl cellulose 
 intravenous contrast is used with neutral agents 
 these agents allow better assessment of mucosal 
enhancement, mural thickness as well as mesenteric 
vasculature 
 better used in unexplained subacute gastrointestinal bleeding 
due to vascular malformation and assessment of 
inflammatory activity and complications of small 
bowel Crohn’s disease
 positive enteral contrast material 
 e.g. (4 to 15% water-soluble (sodium diatrizoate) 
solution or a dilute (1%) barium solution) 
 no intravenous contrast is used with these agents 
 mainly used to detect lower grades of small bowel 
obstruction and internal fistula
procedure 
 Conscious sedation (optional, according to patient's preference) 
 Introduction of the 12 to 14-F enteroclysis tube (under 
fluoroscopy or through duodenoscope). The tube tip is usually 
placed distal to the ligament of Treitz . 
 Contrast is administered either on the fluoroscopy table or after 
transferring the the patient to the CT unit for commencement of 
the CT scan (usually 1.5-2L of oral contrast). 
 In the CT unit, the position of the enteroclysis tube is checked in 
the topogram. 
 In case negative oral contrast will be used, intravenous contrast 
injection will be given (approximately 100-150ml). 
 After completing the scan, the tube is withdrawn gradually to the 
stomach and any extra contrast volume is suctioned.
(a) Coronal reformation of CT enteroclysis image in 45-year-old patient with water as neutral 
enteral contrast material shows hyperenhancement of terminal ileal mucosa (arrowhead) and 
mural thickening. 
Maglinte D D T et al. Radiology 2007;245:661-671 
©2007 by Radiological Society of North America
Coronal reformation of CT enteroclysis image obtained with dilute 0.1% barium sulfate 
in 50-year-old patient with mild active Crohn disease shows similar findings. The barium 
sulfate has slightly higher attenuation (30–50 HU) than water (0–20 HU) and a barely 
visible speckled appearance, probably since it is a suspension of several ingredients, 
including gum, sorbitol, and barium sulfate.
MR Enteroclysis 
 Magnetic resonance (MR) enteroclysis is an emerging 
technique to diagnose small-bowel disease. 
 Potential benefits of MR enteroclysis include direct 
acquisition of coronal plane images and high intrinsic soft-tissue 
contrast resolution, as well as the absence of 
exposure to ionizing radiation. 
 An additional benefit of MR enteroclysis when compared 
with small-bowel follow-through, small-bowel enteroclysis, 
video capsule endoscopy, is the ability to depict 
extraintestinal involvement. 
 sensitivity and specificity of MR enteroclysis in the 
diagnosis of small-bowel neoplasms to be 0.86 and 0.98, 
respectively.
PROCEDURE: 
 After placement of a nasoduodenal tube under 
fluoroscopy the small bowel is distended with 
1000-3000 ml of methyl cellulose and water 
solution using an electric infusion pump, located 
outside the scanner room at an infusion rate of 
800-200ml/min 
 As per the protocol which consists of MR 
fluoroscopy using thick slab 50mm coronal 
HASTE with fat saturation, starting at the 
beginning of infusion and repeated every 8 
seconds during normal breathing. 
 This allows for the study of contrast passage speed, 
luminal distension, peristalisis and retrograde 
filling of stomach.
 Subsequently, every 5 mins, depending on the 
degree of distension observed from the HASTE 
images, coronal and axial TRUFISP sequences with 
fat saturation are performed with a slice thickness 
of 5mm to study morphologic changes. 
 Finally with maximum distension, multislice 
HASTE images with fat saturation and 
unenhanced and enhanced(0.1mmol/kg gado) 
coronal and axial FLASH 2D images with fat 
saturation are obtained 60 sec after contrast 
injection is made
Name of MR sequence by various 
vendors 
SIEMENS GE PHILIPS HITACHI TOSHIBA 
HASTE SINGLE SHOT 
FSE 
SINGLE SHOT 
TSE 
SINGLE SHOT 
FSE 
FACE 
FISP GRASS T1 FFE RF SPOILED 
SARGE, RSSG 
FAST FE 
FLASH SPGR FFE REPHASED 
SARGE 
SSFP 
TRUE FISP FIESTA BALANCED 
FFE 
BALANCED 
SARG/ BASG 
TRUE SSFP 
Haste is fast/turbo spin echo rest are gradient echo sequences
 Haste sequence is T2 weighted FSE sequence – 
provides motion free images 
 Normal bowel wall-hypointense 
 Pathology-Hyperintense 
 Endoluminal negative contrast –low signal intensity 
 So bowel wall pathology is easily made out 
 Limitation-poor depiction of mesentary 
(due to k-space filtering effects)
 3D Flash aequence: T 1 weighted image 
 Bowel wall- hypointense 
 Mesenteric fat-hyperintense 
 Any bowel wall pathology is easily made out and also 
wen combined with fat saturation luminal pathology is 
easily made out 
 Most suitable images for virtual endoscopy by volume 
rendering method 
 High contrast to noise ratio
 TRUFISP: contrast depends on T2/T1 ratio 
 Bowel wall-intermediate signal 
 Fluid :High signal intensity 
 Fast acquisition time- less motion related artifacts 
 No intraluminal flow voids 
 Able to demonstrate mesentary due to good contrast 
between bright peritoneal fat and dark small blood vessels 
and lymphnodes 
Single shot tse sequence with heavily T2 weighting is used to 
check position of placement of catheter
Fast imaging with steady-state precession of MR enteroclysis. Adequate luminal 
distension throughout the jejunum and ileum is seen.
Cor trufi 
haste 
Flash post gado
True FISP (a) and HASTE (b) coronal MR images show homogeneous opacification of the 
lumen. The HASTE image 
was acquired after administration of an antiperistaltic drug to avoid intraluminal flow voids. 
Thickening of the valvulae conniventes (plicae circulares) appears on both images (arrow). 
trufi haste
contrast-enhanced three-dimensional FLASH with fat saturation
 Drawbacks: 
1.Susceptibility weighted artefacts from air bubbles in 
the small bowel due to infusion or air while performing 
the procedure,specially in FISP sequence. 
2.Motion artefacts 
3.Artefacts from previous surgeries
CT enteroclysis 
 Risk of radiation and relatively 
nephrotoxic contrast agents 
 More accurate 
 higher sensitivity and 
interobserver agreement for 
imaging signs of small-bowel 
disease 
 The sensitivity of CT 
enteroclysis for bowel wall 
thickening, abnormal bowel wall 
enhancement, and adenopathy 
was 89%, 79%, and 64%, 
respectively 
 The interobserver agreement for 
these signs varied between 0.52 
and 0.65 for CT enteroclysis 
MR enteroclysis 
 Magnetic resonance (MR) 
enteroclysis has the 
advantage of a lack of 
radiation exposure and safe 
contrast agents 
 less accurate than CT 
enteroclysis 
 Relatively less sensitive 
 For the same signs, the 
sensitivity of MR enteroclysis 
was 60%, 56%, and 14%, 
respectively 
 between 0.15 and 0.48 for 
MR enteroclysis.
PET-CT 
 PET-CT is not first choice, but can be useful if findings 
on CT or MR are equivocal or to look for metastatic 
disease.
Imaging anatomy of small intestine
Imaging anatomy of small intestine
Imaging anatomy of small intestine
Imaging anatomy of small intestine

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Imaging anatomy of small intestine

  • 1.
  • 2. BY Dr. Sateesh kumar Moderators: Dr.Raghuram Dr.Jaipal KMIO
  • 3.  Introduction  Embryology  Gross Anatomy  Blood, Nervous supply  lymphatic drainage  Imaging Modalities Conclusion
  • 4.  Is the longest part of alimentary canal  Extends from pylorus of stomach to  ileocecal junction  Length = 3 m in a living person & 6.5 m in a cadaver (loss of muscle tone)  Diameter = 4 cm in gastroduodenal jn & 2.5 cm at i-c junction. Small bowel represents 75% of the length & 90 % of mucosal surface of intestinal tract.
  • 5.  Site :it occupies all abdominal regions except epigastic and hypochondriac region normally  Fixation :it is stabilized by mesentery  Mesentery = peritoneal fold attaching small intestine to posterior body wall
  • 6.  Anatomical subdivisions :  a) Duodenum  b) Jejunum  c) Ileum  Duodenum = C-shaped tube which is attached to the Stomach.  Jejunum = is the coiled Midportion.  Ileum = the final section,which leads into the large intestine.
  • 7. Embryology:  Duodenum: above and including ampulla of vater is developed from foregut.  Rest from midgut  Jejunum and ileum (except terminal portion) pre-arterial segment of midgut loop.  The terminal portion of the ileum is derived from the post-arterial segment proximal to the caecal bud.  Endoderm gives rise to mucosal lining of small bowel rest of the layers are derived from splanchanic laayer of lateral plate mesoderm.
  • 8.
  • 9.
  • 10. Duodenum:  C-shaped tube  25 cm long & width 3.75-4 cm  Joins stomach to jejunum  The first & shortest part of small intestine  The widest & most fixed part  Curves around the head of  pancreas  Begins at pylorus on right side & ends at duodenojejunal junction on left side  Partially retroperitoneal
  • 11.  Duodenum is divided into four  parts :  a) First (superior) part  b) Second (descending) part  c) Third (horizontal) part  d) Forth (ascending) part  First part of duodenum  It is 5 cm long  Lies anterolateral to body of L1 vertebrae  Most movable part
  • 12. Duodenum  Second part:  It is 8 to 10 cm long  Descends along right sides of L1 through L3 vertebrae  Third part :  It is 10 cm long  Crosses L3 vertebra  Fourth part of duodenum Ascending  It is 2.5 cm long  Begins at left of L3 & rises superiorly as far as superior border of L2 and continues with jejunum
  • 13. ANATOMICAL RELATIONS  FIRST PART-  PERITONEAL RELATIONS: 2.5cms movable and attached to lesser and greater omentum. Next 2.5cms is fixed and retroperitoneal.  VISCERAL RELATIONS:  Anteriorly: Quadrate lobe of liver andGB  Posteriorly: Gastroduodenal A, bile duct and PV  Superiorly: floor of Epiploic foramen.  Inferiorly: Head and neck of pancreas.
  • 14. SECOND PART-  PERITONEAL RELATIONS: retroperitoneal & fixed.  VISCERAL RELATIONS:  Anteriorly: Rt lobe of liver, transverse colon root of transverse mesocolon Posteriorly: Anterior surface of rt kidney, rt renal vessels, rt edge of IVC,rt psoas  Medially: Head of pancreas and bile duct.  Laterally: Rt colic flexure
  • 15. THIRD PART-  PERITONEAL RELATIONS: retroperitoneal & fixed.  VISCERAL RELATIONS:  Anteriorly: Superior mesenteric vessels  Posteriorly: Rt ureter, rt psoas major, rt testicular or ovarian vessels, IVC abdominal aorta.  Superiorly: Head of pancreas.  Inferiorly: Coils of jejunum.
  • 16. FOURTH PART-  PERITONEAL RELATIONS: retro-peritoneal & mobile.  VISCERAL RELATIONS:  Anteriorly: Transverse colon & mesocolon, lesser sac & stomach.  Posteriorly: Lt sympathetic chain, lt psoas, lt renal vessels, lt testicular veins & inferior mesenteric vein.  To the right: attachment of upper part of root of mesentry.  To the left: Left kidney & ureter.  Superiorly: Body of pancreas.
  • 17. Ligament of trietz  Suspensory ligament of duodenum  Fibromuscular band arising from rt crus of diaphragm close to oesophageal opening and attaches to posterior surface of D-J Flexure  Upper 1/3- striated muscle  Middle 1/3- elastic tissue  Lower 1/3- smooth muscle
  • 19.  smooth muscle lining of 1st part of duodenum is longitudinal  plicae circularis  (circular folds) of 2nd part of duodenum  Major duodenal papilla is a small rounded elevation at site where bile duct & main pancreatic duct pierce medial wall of 2nd part of duodenum
  • 20. JEJUNUM & ILEUM  Jejunum begins at duodenojejunal flexure (L2) & ileum ends at ileocecalJunction.  Jejunum & ileum = 6 to 7 m long (jejunum 2/5, ileum 3/5)  Coils of jejunum & ileum are suspended by mesentery from posterior abdominal wall & freely movable.  Most jejunum lies in leftupper quadrant & most ileum lies in right lower quadrant
  • 21.
  • 22.
  • 23.
  • 24.  Wall of small intestine is made of the following layers :  a) Serosa coat  b) Muscular coat  c) Submucosa coat  d) Mucosa coat  Serosa: made of peritoneum  Muscularis: made of smooth muscle fibers arranged in outer longitudinal & inner circular layers  Submucosa : contains loose CT & large venous plexuses (submucosa of duodenum contains duodenal or Brunner’s glands)  Mucosa composed of a layer of epithelium, lamina propria & muscularis mucosa (Plicae circulares numerous in jejunum, Peyer’spatches present in ileum)
  • 25.
  • 26.  Intestinal crypt epithelium  Secretory cells that produce intestinal juice  Enteroendocrine cells  Intraepithelial lymphocytes (IELs): Release cytokines that kill infected cells  Paneth cells:Secrete antimicrobial agents (defensins and lysozyme)  Stem cells
  • 27.  Duodenum  Arterial supply: Upper half is supplied by superior pancreaticoduodenal(gatro-duodenal)  Lower half is supplied by inferior pancreaticoduodenal(SMA)  Venous drainage  Superior pancreaticoduodenal vein drains into portal vein  inferior vein joins superior mesenteric vein.
  • 28. Blood supply:  Ileum and Jejunum Arterial supply: Branches of superior mesenteric artery  Intestinal branches arise from left side of the artery & run in mesentery to reach the gut (gastrointestinal tract)  They anastomose with one another to form as series of arcades  Lowest part of ileum is supplied by ileocolic artery  Venous drainage  Veins correspond to branches of superior mesenteric artery & drain into superior mesentery vein
  • 29.
  • 30. Lymphatic drainage:  Duodenum:  Lymph vessels follows arteries & drain upward via pancreaticoduodenal nodes to gastroduodenal nodes & then to celiac nodes .  Downward via pancreaticoduodenal nodes to superior mesenteric nodes around origin of superior mesentery artery  Jejunum & Ileum: Lymph vessels pass through many intermediate mesenteric nodes & finally reach superior mesenteric nodes (situated around origin of mesenteric artery)
  • 31.
  • 32. Nerve Supply:  Duodenum:  Nerves are derived from sympathetic (T6-T9)& parasympathetic (vagus) nerves from celiac & superior mesenteric plexuses  Jejunum & Ileum:  Nerves are derived from sympathetic & parasympathetic (vagus) nerves from superior mesenteric plexus
  • 33. Mesentary:  Broad fan shaped fold of peritoneum that suspends jejunum and ileum from posterior abdominal wall  Conveys nutrition and innervation  Consists of 2 layers derived from greater sac  Root- 15cms long extends from left side of L1 vertebrae at duodenojejunal junction to Rt Sacro-iliac joint at ileo-caecal junction.  Free border separates to enclose jejunum n ileum
  • 34.
  • 35. Need for imaging • Small bowel diseases presents with non specific symptoms. • Small bowel represents 75% of the length & 90 % of mucosal surface of intestinal tract. • Diagnostic tests which can provide documentation of structural abnormality or normality. • Limited role of enteroscopy of small bowel has retained barium examination of small bowel as primary investigation for its mucosa.
  • 36. Plain abdominal Radiograph: Most commom indication suspected bowel obstruction /Perforation . Views Supine Erect Lateral dorsal decubitus Antero-posterior or posteroanterior left lat decubitus Erect PA chest
  • 38. NORMAL GAS PATTERN  Stomach - always  Small bowel - 2 or 3 loops of non-distended bowel - normal diameter = 2.5-3 cm  Larger bowel - in rectum or sigmoid colon - always
  • 39.
  • 40.  Fluid levels:  3 to 5 fluid levels < 2.5 cm in length may be seen particularly in the right lower quadrant. More than 2 fluid levels in dilated small bowel more than 2.5 cm caliber are abnormal and usually indicate paralytic ileus or intestinal obstruction
  • 41. NORMAL FLUID LEVELS  Stomach - always (except supine film)  Small bowel - 2 or 3 levels possible  Large bowel - none normally
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49. Usg-small bowel:  Both standard (2.5–6 MHz) abdominal convex probe and high resolution (7.5–14 Mhz) probe are used  All parts of small bowel—duodenum, jejunum and ileum are accessible to TUS examination.  Isosmotic polyethylene glycol (PEG) solution 1000 mL is required for small intestine contrast sonography (SICUS) enteroclysis or hydrosonography of SB.
  • 50. GUT SIGNATURE  The sonographic layers appear alternately echogenic and hypoechoic  the first, third, and fifth layers are echogenic,  the second and fourth layers are hypoechoic.  muscular components of the gut wall—the muscularis mucosa and the muscularis propria—constitute the hypoechoic layers on  sonography
  • 51.  The quality of the scan and the resolution of the transducer determine the degree of layer differentiation  Normal intestinal wall thickness is generally ≤ 3 mm (using mild compression) ranging from small diameters in the jejunum, ileum  5mm is considered upper limit for non-distended bowel  Physiological contraction of the intestine leading to a thickened wall segment may cause misinterpretation, therefore bowel motions have to be taken into account before measurements are performed  In addition to wall thickening, echomorphology (integrity of wall architecture) and surrounding structures have also to be considered in the interpretation of the intestinal wall diameter.
  • 52.  Normal small bowel: Transverse view of pars horizontalis duodeni between aorta and SMA.
  • 53. Normal small bowel: Longitudinal view of jejunum in left mesogastrium—with numerous valvulae conniventes. Longitudinal section of terminal ileum (TI) in the left iliac fossa
  • 54. Valvulae conniventes (plicae circulares) of the small bowel. These are more easily seen when there is fluid in the lumen of the bowel
  • 55.
  • 56.  Sonographic appearance of an inflamed colon segment in Crohn’s disease. Characteristic appearance: thickened wall diameter (almost 1 cm), partial loss of wall stratification, prominent submucosal layer, narrowed lumen and mesenteric fat hypertrophy.
  • 57.  Small Intestine Contrast Ultrasonography (SICUS) or Hydrosonography. TUS with using oral contrast solution (iso-osmolar nonabsorbable polyethylene glycol solution (PEG). The amount of PEG solution used in different studies varies between 200 and 2000 mL.  On average, the entire small intestine could be visualized on ultrasonography by about 45 min after the ingestion of 600 mL or less of contrast solution without any side effects .  SICUS improves TUS resolution by separating of SB walls and eliminating bowel gas.  Compared with conventional sonography luminal filling can improve visualisation of bowel walls and fold pattern but extends time of examination (vary between 30–40 min).  In the study of Pallotta et al. SICUS is proved superior to that of standard TUS in detecting the presence, number, extension, and sites of small bowel lesion
  • 58.  Color Flow (Power) Doppler—CFD. It is used to estimate presence, density or absence of vascular signals in thickened segments of bowel wall, in intraluminal or extraluminal pathological structures and for imaging flow in big abdominal vessels—SMA, coeliac trunk, portal vein. CFD is part of standard abdominal and bowel sonography.  2cm after the SMA branches off from the aorta, and as it runs parallel to the aorta  Triplex Scanning or Color Assisted Duplex Scanning (TUS + CFD + PWD). Enables evaluation of SMA/CA flow and intramural flow in thickened bowel segments
  • 59.  Readily detected color  Doppler flow and a resistive index less than 0.6 wereconsistent with inflammation Cross-sectional images of ileum proximal to an obstructing lesion. The lumen is distended with fluid. The wall is slightly thick. ON Color Doppler image marked hyperemia of the gut wall as a reflection of its inflammation
  • 60.
  • 61.  Non-invasiveness and lack of radiation, makes TUS is a relatively good alternative to CT or MRI enterography, particularly in young patients and pregnant women.  In the duodenum and terminal ileum, TUS can detect the most of benign and malignant tumors.  TUS is easily available , noninvasive, and low-cost diagnostic procedure.  significant limitations (obesity, meteorism)  In the hands of experienced examiner offers reliable tool for SB diseases examination.
  • 62. Barium Techniques  Barium studies classified into indirect and direct techniques.  Indirect techniques examine the SI with barium that has passed through the upper GIT or colon before entering the SI and include the  follow through examination/dedicated follow throgh  complete reflux examination (retrograde exam.)  peroral pneumocolon examination of the ileocaecal region
  • 63.  Direct technique  Enteroclysis (small bowel enema) involve introducing barium or other contrast agents directly through a tube into the distal duodenum, proximal jejunum, or the more distal SI
  • 64. Indications Contraidications  Patients who have low suspicion of small bowel disease – abdominal pain and diarrhea  Suspected complete or near complete small bowel obstruction  Crohn’s diease  Patients eho refuse for placement of nasojejunal tube/bilbao catheter  Colonic obstruction  Suspected perforation  Paralytic ileus
  • 65. Contrast media  Medium density barium suspension (50-60%w/v)  Suspending agent to prevent flocculation and maintain stability  High density barium(200-250%) may produce an appearance of fold thickening and clumping of small bowel  Acid Baso4 suspension may produce spasm,enlarged folds and dilatation of duodenum & jejunum  Alkaline Baso4 suspension improves coating of valvulae and improves diagnostic accuracy
  • 66.  Entrobar is a raspberry flavored barium sulfate suspension. It is a contrast medium developed for use in enteroclysis and follow-through x-ray examinations of the small intestine.  The product contains 50% w/v barium sulfate USP, suspending and dispersing agents, simethicone, citric acid, potassium sorbate, flavoring, sodium citrate, saccharin sodium and water. Barium sulfate has the empirical formula of BaSO4.  Barium sulfate is an insoluble material which, because of its density, provides a positive contrast during x-ray examination. Barium sulfate is an inert radiopaque material which is not absorbed or metabolized and is eliminated intact from the body in a manner similar to other non-absorbed inorganic materials. Excretion rate is a function of gastrointestinal transit time.
  • 67. Preparation  Purgative-Dulcolax 2tab HS (not in suspected obstruction,acute crohns exacerbation,ileostomy)  Low roughage high fluid intake diet 48hrs prior  No food/fluid should be taken for 12hrs before investigation  No antispasmodics codeine tranquilizers 24-48hrs prior
  • 68. Barium follow-through examination  This is performed following a barium meal examination of the esophagus, stomach and duodenum  150ml 250%w/v—200ml 20-25%--250ml40-45%  As the barium column progresses through the small intestine large radiographs of the abdomen are taken at intervals  First one is taken with the patient supine about 15 minutes after the barium meal and shows the proximal jejunum
  • 69.  The remaining radiographs are normally taken at half hourly intervals with the patient prone.  When the barium column reaches the caecum spot views of the terminal ileum are taken  It takes from 2 to 6 hours for the head of the barium column to reach the caecum
  • 70. Dedicated small bowel follow through  Single contrast technique  Barium 50-60% 600-900ml  Drink as rapidly as possible  To right lateral position 15-20mins  Then prone filming done every 15-20min until ileocaecal junction opacification noted  To demonstrate ileocaecal junction supine right is best as ileum enters caecum posteromedially  Always empty the bladderprior to these spot films
  • 71. Single contrast technique Positioning Purpose First Right side down dependent To aid gastric emptying Second Prone To separate bowel loops Third Right side up To visualize IC junction
  • 72.  Periodic fluoroscopic examination and compression spot films are recommended  4 spot films for ileocaecal junction should be taken with variable degree of compression  Compression over bowel loops to avoid overlap thereby prevents efffacemen of mucosa and small lesions may not be missed  The abnormality must be shown in 2 spot films taken at different times to confirm persistence of lesion
  • 73.  Overlap of contrast filled bowel loops in pelvis  Overcome by  Table head down  30 degree caudal angled view of pelvis  Emptying urinary bladder prior to filming ileal loops  Peristalisis can be increased by metoclopromide neostigmine cck glucagon  20-40ml sodium/meglumine ditriazoate or gastrograffin to barium increases transit time  Cold water- inc palatibility speeds gastric emptying
  • 74. Interpretation Jejunum Ileum Constitutes proximal 2/5ths of small intestine 3/5ths Position Upper left and periumblical region Lower right hypogastric and pelvic region Max. diameter 4 cm 3 cm Number of folds 4-7 per cm 3-5 per cm Pattern Feathery mucosa Less feathery or maybe absent Fold thickness 1.5-2mm bowel wall depth 1-1.5mm
  • 75. BA Meal follow through:
  • 76.
  • 77. The pattern of the mucosal lining of the first part of the duodenum is different from the other parts. longitudinal pattern of the mucosa of the first part of the duodenum forming what is known as the duodenal cap This pattern is very similar to that of thepylorus of the stomach This pattern changes to a more flecked appearence in the distal duodenum
  • 78.
  • 79. Reflux examination  Barium and air refluxed through the ileocaecal valve during a barium enema examination give good views the terminal ileum. Replaced by enteroclysis  The radiographs should be studied carefully and spot views of the distal ileum is taken if necessary  All of the small intestine can be examined by refluxing barium from the colon into the terminal ileum – the complete reflux examination
  • 80. doublecontrast barium enema examination (with reflux into terminal ileum) shows carcinoid tumor in terminal ileum Doublecontrast barium enema examination (with reflux into terminal ileum) shows lipoma as smooth, ovoid, submucosal mass in distal ileum
  • 81. Peroral Pneumocolon examination  Excellent view of the terminal ileum and caecum can be obtained by giving barium orally and when the head of the barium column has reached the ascending colon introducing air per rectum and refluxed in to distal ileum  Glucagon can be used to relax ileocaecal valve  This procedure shows Crohn’s disease and carcinoma of the caecum particularly well
  • 82. Per oral pneumocolon examination Indications contraindicatns  Terminal ileum porly visualized on routine compresion spot films .  Clinical suspicon of Crohn disease with normal apearance of terminal ileum  abnormal apearance of terminal ileum on routine compresion spot films  history ileocolic anastomosis.  Recent colonic or rectal biopsy
  • 83.
  • 84. Advantages Disadvantages  Easily performed  No catheterisation  Physiologic transit time can be assessed  Overlapping of barium filled bowel loops in pelvis  Poor distension  Partial or intermittent bowel obstruction  Operator dependant  Time consuming
  • 85. Complicaions  Leakage of barium form unsuspected perforation  Aspiration  Impacted barium converts partial obstruction in to complete obstrction  Barium appendicitis impaction at appx
  • 86. ENTEROCLYSIS (small bowel enema) INDICATIONS  Partial small bowel obstruction  Crohn’s ds  Suspected meckel’s diverticulum  Malabsorption  Neoplasms (cancers)  Occult GI bleeding  Equivocal BMFT but strong clinical suspicion
  • 87. CI  Complete colonic obstruction  Duodenal obstruction n GJ  Suspected perforation  Massive dilatation of small bowel  Paralytic ileus
  • 88. Normal follow through Enteroclysis - normal small bowel mucosa 23
  • 89. catheter  1)bilbao dotter tube – 22F polyethylene,150cm  2)silk tube  3)Maglinte balloon enteroclysis catheter
  • 90. Bilbao dotter tube  Bilbao Dotter tube is (22 F polyethylene tube which is 150 cms long with a guide wire which is 5 cms shorter than the tube, with multiple side holes which are 8 in number without an end hole  guide wire is teflon coated to reduce friction).  Latest modified catheters(10F-14F)  children 7F caths are used
  • 91.
  • 92. Maglintos Balloon enteroclysis catheter  Modification of the 1 4 French Bilbao duodenal tube  Made of radiopaque polyvinyl chloride  1 60 cm - length, inner diameter -0.1 1 0 mm and an outer diameter of 0.1 70 mm (1 3 French).  Six side holes measuring 0.70 inches (1 8 mm) in diameter are located distal to the latex balloon.  This closed-end catheter has a weighted tip 5 cm distal to the balloon, attached proximal to the last row of side holes .  Balloon lumen measures 0.030 inches (0.76 mm) and is provided with a one-way check valve attached adjacent to the open end of the catheter.  About 12-15 ml of air gauged fluoroscopically is injected once the  catheter tip is in the desired position.  A 1 80-cm-long, Teflon-coated, stainless-steel, braided torque guide wire  0.065 inches (1 .7 mm) in outer diameter is provided with a straight tip to act as a stiffener and angled tip fordirectional or torque control.
  • 93. Advantages  material does not have to be held up by normal pyloric activity  Quicker  increase in distention of lumen  Disease that reduce this distention –easily identified
  • 94. Disadvantages  placement of enteroclysis catheter  higher doses of radiation
  • 95. Contrast medium  Single – 20% w/v suspension of micropulverised barium with added suspending agent in alkaline medium  Double – high density low viscosity 200 – 250% Ba + methylcellulose Ba + air – air double contrast EC adv : mucosal detail superior to any other examination 10gms of carboxymethylcellulose added to 2litres of warm water. Refrigerate mixture overnite and shake well before use
  • 96.
  • 97. Why methylcellulose?  Commonly used as bulk laxative and suspending agent  Non irritating to bowel mucosal lining  Unable to be absorbed  No toxic effects on body  Natural tendancy to retain water in lumen promotes peristalisis and prevents luminal collapse.  Propels barium to distal ileum and colon  Low diffusivity with compatiable ba suspension and thus preserves an interface between dense barium coating of mucosa and luminal water density  Promotes evaccuation by laxative effect
  • 98. Patient preparation  Non-residue liquid diet(a day prior)  NPO(after midnight)  Medication – reduce motility (a day prior)  Laxative – magnesium citrate/bisacodyl(CI-partial obst)  Asc col and terminal ileum clear from stool  Drugs –  antich, ganglion blocking – diltn-mimic sprue  Narcotics  For infants, 4 hrs fasting ,sedation.
  • 99. Contrast dose : Age dose 3-5 mnths- 200ml 5-8 mnths- 300ml 8-11 mnths- 400ml 1-3 yrs- 500ml Children And adults- 1-1.5 litres
  • 100. Inflation of baloon  15 to 20 ml  Beyond lig of Treitz  Reflux into stomach – distention, nausea
  • 101.  Infusion of Barium 70 to 75 ccs/min  Infusion of methyl cellulose 70 to 120 ccs/min  important that ba advance in an uninterrupted column and w/o causing focal distention of lumen.
  • 102. Technique:  Preliminary plain radiographs of the abdomen: To determine wether the patient is adequately prepared and to exclude the presence of barium from previous examinations. Free intraperitoneal air, displacement of bowel loops by mass, calcification and abnormality of bowel loops other than distension.
  • 103. Procedure:  Patient sits upright on a chair placed against the wall so not to move away from the advanced tube. Alternatively, in a patient who cannot sit up, the tube can be placed with the patient supine or right lateral on the fluoroscopy table.  2-3 cc 2% xylocaine jelly is intorducd into the nostril through which the tube to be placed after ensuring no nasal blockage, with patients neck hyperextended.  The Bilbao-dotter tube without the guide wire is inserted through one of the nostrils and advanced with the swallowing action of the patient till the tip reaches stomach.  About 5-7 cms of the tube is passed in stomach and then neck is flexed.  Guide wire may be used to stiffen the tube to assist advancement through the esophagus into the stomach.
  • 104.  Further it is advanced through the antrum into pyloric canal, now with guidewire 5cms proximal to tube tip, the tube is advanced till the tube enters duodenal cap, which may be facilitated by turning the patient supine with right side up so that the location of pyloric canal and duodenal cap can be seen outlined by air.  With further advancement the tube tip is placed at the duodenojejunal flexure with tip of guide wire in pyloric canal.  Finally the tube tip should be 4-5 cms distal to the ligament of treitz. Such a placement prevents reflux of barium and CMC into proximal parts of duodenum.
  • 105. If stomach is collapsed or has very little gas, injectin 100-150 ml of air will help the above manipulation. If stomach is overdistended with gas, aspirate out air to reduce distension If residual fluid in stomach,should be aspirated prior to manipulation While advancing the tube it will tend to hold up at the following places due to acute angulation of the intestine, junction of 1st- 2nd part duodenum;junction of 2nd-3rd parts of duodenum;duodenojejunal flexure
  • 106.
  • 107.
  • 108. Problems:  Prolonged examination time: it is due to improper flow rates. Too high infusion rates should not be used. To restore peristalisis , inj.metoclopromide 10 mg IV is useful  Incomplete distension of small bowel: due to slow infusion rates, or due to excessive dose or response of metoclopromide. Increasing the rate of flow of contrast will solve the problem  Prolapse of small bowel into pelvis: few loops may dip into the pelvis, angled compression allows lifting of pelvic segments . If caecum obscures pelvic ileum, patient is turned prone and the table is tilted head down. This allows caecum to empty and terminal ileum becomes visible.  Fecal material in terminal ileum: due to incompetent ileocaecal valve or in patients who are chronic laxative users, infusion of adequate amount of methylcellulose will push debris into the colon
  • 109.  Reflux into the duodenum and stomach: this is due to too fast infusion rate or small bowel obstruction. Incidence can be reduced by the use of ballon enteroclysis catheter. In patients with obstruction, preliminary decompression of stomach and proximal jejunum decreases reflux.
  • 110.  Single contrast enteroclysis: This is performed in patient with a high grade partial small bowel obstruction. Barium suspension 20%w/v is injected at the rate of 75- 120 ml/min An average of 1-1.5 lts of barium suspension in injected without any interruption Average time taken to reach the ileo-caecal junction is about 15 mins. Interrupted fluoroscopy is used to follow the head of the barium column Stenotic lesions are best identifiable at the head of the column
  • 111.  Filming: One film for the jejunal loops, another film is taken for the entire small bowel. Spot films are taken with or without compression where ever necessary Spots of the ileocecal junction are done All filming is done with high kVp technique(120-140 kV)
  • 112.  Double contrast enteroclysis: 150-500 ml barium suspension(200-250% w/v) is injected at a rate of 80-100 ml/min, till the proximal ileum is reached. After this , 0.5 %suspension of CMC is injected at a rate of 75-120ml/min. Ileocaecal spot film should be taken initially when the barium column reaches the IC junction and again when the IC junction is in double contrast.
  • 113.  Filming: Upper abdomen when jejunum is seen in double contrast Full abdomen when entire small bowel is in double contrast Ileocaecal junction spots in single and double contrast filming has to be completed within 20-25 mins for good double contrast effect Erect films donot give any additional information of small bowel study
  • 114. Small bowel enema Small bowel follow through
  • 115. Normal enteroclysis demonstrating catheter in first jejunal loop and well distended jejunum and proximal ileum with normal pattern of valvulae conniventes
  • 116. Normal small bowel:  Fold shape: The folds are less pronounced or possible absent in the ileum. The folds run fairly straight and parallel, joining the bowel wall in the form of rounded corners. At times in the ileum, the folds may crowd together on the concave side of a bowel loop, creating a triangular fold pattern.
  • 117.  Fold thickness: The folds are normally 1.8 mm thick in the jejunum, and 1.5 mm thick in the ileum. When the thickness exceeds 2.5 mm in the jejunum or 2.0 in the ileum, it is considered a pathologic finding.
  • 118.  Number of folds: 4 to 7 folds per inch are normal for the proximal jejunum and 2 to 5 folds per inch is normal for the distal ileum
  • 119.  Fold Height. The height of the folds is 3 to 7 mm in the jejunum and 1.5 to 3.5 mm in the ileum. the height of the folds may vary considerably within the same segment of the bowel, thus the visualization of the entire segment for the height of the folds is must
  • 120.  Lumen Diameter: There is a gradual decrease in lumen diameter from the jejunum into the ileum. The upper jejunum averages from 3.0 cm to 4.0 cm, 2.5 cm to 3.5 in the lower jejunum, and 2.0 cm to 2.8 cm in the ileum. Abnormal diameters are anything that exceeds 4.5 cm in the upper jejunum, 4.0 cm in the distal jejunum, and 3.0 in the ileum.
  • 121. Wall Thickness: When two adjacent loops are found to be parallel over a distance of at least 4 cm, with abdominal compression, the distance between the two represents the combined wall thickness. Half of this measurement is the thickness of a single loop. The wall thickness is the same throughout the small bowel. A wall thickness greater than 4 mm is considered abnormal.
  • 122. Air double contrast enteroclysis: 150-200ml Barium @ 60ml/min Intermittent fluoroscopy to visualise barium reaching terminal ileum. Inject 200ml of air @ 100ml/min initially A total of 600-1000ml air is necessary Antispasmodic iv/im when air reaches distal ileum Mucosal details superior Minimal narrowing is missed as air passes through Uncomfortable for patient
  • 123. Comparision:  Methylcellulose DC enteroclysis 1.Less information 2.Simple procedure 3.Less time(20-30 mins)  Air double contrast enteroclysis More clear detail Operator dependent Relatively longer time
  • 124. ADVANTAGES OF ENTEROCLYSIS  Contrast material is administered at a desired rate and not influenced action of pyloric sphincter  Direct infusion at a rate that produces hypotonia, completely dilates the small intestine and therefore the fold patterns and mucosal abnormality can be easily assessed.  Because the distensibility if bowel lumen is challenged by enteroclysis, the bowel proximal to stenosis dilates thus facilitating recognition of even a minimal narrowing.
  • 125.  Sinuses and fistulous tracts can be demonstrated by enteroclysis  Can be completed in less time  Enteroclysis tube may be left in place in patients with obstruction to achieve better decompression  Enteroclysis permits better delineation of the small bowel than that achieved by BMFT, segmentation and flocculation can be avoided.
  • 126. Disadvantages Placement of the nasoenteric tube causes discomfort which can be minimised by sedation Extrapyramidal symptoms of metaclopramide can be made to subside by giving atropine or benadryl Nausea and vomiting due to inadequate tube placement proximal to ligament of treitz. Treatment: aspiration of contents by withdrawing the tube into the stomach Diarrhoea if large amount of fluid is given
  • 127.  Rapid colonic emptying  Use of barium as primary contrast  Operator dependent  Failure to depict extraintestinal changes After care: The patient should be warned that diarrhoea may occur as a result of the large volume of fluid given Complications: Aspiration Perforation of bowel
  • 128. Enterography vs Enteroclysis  Oral contrast  Enteral catheter  Better distension
  • 129. CT Enterography  non-invasive technique for diagnosis of small bowel disorders.  Advantages  evaluates the entire thickness of the bowel wall  offers information about the surrounding mesentery the mesenteric vasculature and the perienteric fat  useful in the assessment of the solid organs and provides global overview of the abdomen
  • 130.  non-invasive technique for diagnosis of small bowel disorders.  Adequate luminal distension is necessary as collapsed bowel loops may mimic pathology. CT enterography utilizes two types of contrast:  neutral oral contrast agents  these have attenuation similar to that of water e.g. water, PEG electrolyte solution, methyl cellulose  intravenous contrast is used with neutral agents  these agents allow better assessment of mucosal enhancement, mural thickness as well as mesenteric vasculature, this is important especially in the evaluation of Crohn's disease
  • 131.  positive contrast agents  such as a dilute (1%) barium solutions  they are not routinely used in CT enterogrpahy  pathologic mural enhancement and intestinal hemorrhage are obscured by positive contrast agents  mainly used to detect lower grades of small bowel obstruction and internal fistula
  • 132. procedure  Abstain from all food and drink 4-6 hours before the exam.  Patients drink about 1.5- 2 L of oral contrast over 40-60 minutes.  Administration of intravenous contrast injection at a rate 4 ml/sec.  CT scanning is ideally performed on a multi-detector computed tomography (MDCT) scanner about 45-65 seconds after contrast material injection in a single (venous) phase or dual (arterial & venous) phases for the evaluation of mesenteric vasculature or GI tract bleeding.  Data interpretation with the use of axial and coronal reformatted images for proper evaluati
  • 133.
  • 134.
  • 135. MR Enterography  Technique  patients should abstain from all food and drinks for 4-6 h prior to the study  patients drink about 1-1.5 L of a 2.5% mannitol solution at regular intervals over a period of approximately 40 min prior to the study  this solution acts as a hyperosmolar agent which draw fluid into the bowel & (biphasic) appears as low signal intensity on T1-weighted images and high signal intensity on T2-weighted images  scanning is ideally performed on a 1.5-T MRI scanner, using a phased array surface coil, either in the supine or prone position
  • 136. MR ENTEROGRAPHY  MR protocol  comprehensive MR examination of the small bowel usually requires axial and coronal both T1 and T2 weighted images  high-resolution ultra-fast sequences such as true fast imaging with steady-state precession (true FISP) and HASTE sequences with and without fat suppression are usually used  fat-suppressed three-dimensional (3D) T1-weighted breath-hold gradient-echo images of the abdomen and pelvis before and after intravenous gadolinium-based contrast material administration
  • 137. CT Enteroclysis  Computed tomographic (CT) enteroclysis is a hybrid technique that combines the methods of fluoroscopic intubation-infusion small-bowel examinations with that of abdominal CT  CT enteroclysis can be performed by using positive enteral contrast material without intravenous contrast material and neutral enteral contrast material with intravenous contrast material.  CT enteroclysis has been shown to be superior to other imaging tests such as peroral small-bowel examinations, conventional CT, and barium enteroclysis, except in the demonstration of early apthous ulcers of Crohn disease.
  • 138. Technique:  Patient positioning: Head first, supine with arms extended above the level of head.  Topogram position/ landmark: Anteroposterior ; level of nipples to 3 cms below the inferior border of the symphysis pubis  Mode of scanning: helical with single breath hold technique.
  • 139.  Scan orientation: craniocaudal Starting location- 1cm above the highest point of the dome of diaphragm End location- base of the bladder.  Gantry tilt-nil  Field of view-just fitting the abdominal wall  Contrast administration- intravenous monphasic and enteral via the nasoenteral tube  Enteric contrast:paraffin solution or polymethyl cellulose at a rate of 40-50 ml/ min  IV contrast-60-100 ml
  • 140.  Rate of contrast injection:2-3ml/sec  Scan delay-40-50 sec  Slice thickness in reconstruction-3-5 mm  Slice interval in reconstruction-1.5-2.5mm  Reconstruction algorithm- medium smooth  3D reconstructions-MPR,MIP,VRT
  • 141.  Patient is kept on overnight fasting before the examination.  Antigas and cathartics are given for bowel cleansing  Lots of fluids are prescribed to counteract the cathartic effects of the study( when high osmotic substance like mannitol/paraffin/polymethylcellulose are used).  The enteral contrast material is administered via the nasoenteric tube with its tip placed at the duodenojejunal flexure.
  • 142.  CT enteroclysis utilises mainly two types of contrast :  neutral contrast media  these have attenuation similar to that of water e.g. water, methyl cellulose  intravenous contrast is used with neutral agents  these agents allow better assessment of mucosal enhancement, mural thickness as well as mesenteric vasculature  better used in unexplained subacute gastrointestinal bleeding due to vascular malformation and assessment of inflammatory activity and complications of small bowel Crohn’s disease
  • 143.  positive enteral contrast material  e.g. (4 to 15% water-soluble (sodium diatrizoate) solution or a dilute (1%) barium solution)  no intravenous contrast is used with these agents  mainly used to detect lower grades of small bowel obstruction and internal fistula
  • 144. procedure  Conscious sedation (optional, according to patient's preference)  Introduction of the 12 to 14-F enteroclysis tube (under fluoroscopy or through duodenoscope). The tube tip is usually placed distal to the ligament of Treitz .  Contrast is administered either on the fluoroscopy table or after transferring the the patient to the CT unit for commencement of the CT scan (usually 1.5-2L of oral contrast).  In the CT unit, the position of the enteroclysis tube is checked in the topogram.  In case negative oral contrast will be used, intravenous contrast injection will be given (approximately 100-150ml).  After completing the scan, the tube is withdrawn gradually to the stomach and any extra contrast volume is suctioned.
  • 145. (a) Coronal reformation of CT enteroclysis image in 45-year-old patient with water as neutral enteral contrast material shows hyperenhancement of terminal ileal mucosa (arrowhead) and mural thickening. Maglinte D D T et al. Radiology 2007;245:661-671 ©2007 by Radiological Society of North America
  • 146. Coronal reformation of CT enteroclysis image obtained with dilute 0.1% barium sulfate in 50-year-old patient with mild active Crohn disease shows similar findings. The barium sulfate has slightly higher attenuation (30–50 HU) than water (0–20 HU) and a barely visible speckled appearance, probably since it is a suspension of several ingredients, including gum, sorbitol, and barium sulfate.
  • 147.
  • 148. MR Enteroclysis  Magnetic resonance (MR) enteroclysis is an emerging technique to diagnose small-bowel disease.  Potential benefits of MR enteroclysis include direct acquisition of coronal plane images and high intrinsic soft-tissue contrast resolution, as well as the absence of exposure to ionizing radiation.  An additional benefit of MR enteroclysis when compared with small-bowel follow-through, small-bowel enteroclysis, video capsule endoscopy, is the ability to depict extraintestinal involvement.  sensitivity and specificity of MR enteroclysis in the diagnosis of small-bowel neoplasms to be 0.86 and 0.98, respectively.
  • 149. PROCEDURE:  After placement of a nasoduodenal tube under fluoroscopy the small bowel is distended with 1000-3000 ml of methyl cellulose and water solution using an electric infusion pump, located outside the scanner room at an infusion rate of 800-200ml/min  As per the protocol which consists of MR fluoroscopy using thick slab 50mm coronal HASTE with fat saturation, starting at the beginning of infusion and repeated every 8 seconds during normal breathing.  This allows for the study of contrast passage speed, luminal distension, peristalisis and retrograde filling of stomach.
  • 150.  Subsequently, every 5 mins, depending on the degree of distension observed from the HASTE images, coronal and axial TRUFISP sequences with fat saturation are performed with a slice thickness of 5mm to study morphologic changes.  Finally with maximum distension, multislice HASTE images with fat saturation and unenhanced and enhanced(0.1mmol/kg gado) coronal and axial FLASH 2D images with fat saturation are obtained 60 sec after contrast injection is made
  • 151. Name of MR sequence by various vendors SIEMENS GE PHILIPS HITACHI TOSHIBA HASTE SINGLE SHOT FSE SINGLE SHOT TSE SINGLE SHOT FSE FACE FISP GRASS T1 FFE RF SPOILED SARGE, RSSG FAST FE FLASH SPGR FFE REPHASED SARGE SSFP TRUE FISP FIESTA BALANCED FFE BALANCED SARG/ BASG TRUE SSFP Haste is fast/turbo spin echo rest are gradient echo sequences
  • 152.  Haste sequence is T2 weighted FSE sequence – provides motion free images  Normal bowel wall-hypointense  Pathology-Hyperintense  Endoluminal negative contrast –low signal intensity  So bowel wall pathology is easily made out  Limitation-poor depiction of mesentary (due to k-space filtering effects)
  • 153.  3D Flash aequence: T 1 weighted image  Bowel wall- hypointense  Mesenteric fat-hyperintense  Any bowel wall pathology is easily made out and also wen combined with fat saturation luminal pathology is easily made out  Most suitable images for virtual endoscopy by volume rendering method  High contrast to noise ratio
  • 154.  TRUFISP: contrast depends on T2/T1 ratio  Bowel wall-intermediate signal  Fluid :High signal intensity  Fast acquisition time- less motion related artifacts  No intraluminal flow voids  Able to demonstrate mesentary due to good contrast between bright peritoneal fat and dark small blood vessels and lymphnodes Single shot tse sequence with heavily T2 weighting is used to check position of placement of catheter
  • 155. Fast imaging with steady-state precession of MR enteroclysis. Adequate luminal distension throughout the jejunum and ileum is seen.
  • 156. Cor trufi haste Flash post gado
  • 157. True FISP (a) and HASTE (b) coronal MR images show homogeneous opacification of the lumen. The HASTE image was acquired after administration of an antiperistaltic drug to avoid intraluminal flow voids. Thickening of the valvulae conniventes (plicae circulares) appears on both images (arrow). trufi haste
  • 159.  Drawbacks: 1.Susceptibility weighted artefacts from air bubbles in the small bowel due to infusion or air while performing the procedure,specially in FISP sequence. 2.Motion artefacts 3.Artefacts from previous surgeries
  • 160. CT enteroclysis  Risk of radiation and relatively nephrotoxic contrast agents  More accurate  higher sensitivity and interobserver agreement for imaging signs of small-bowel disease  The sensitivity of CT enteroclysis for bowel wall thickening, abnormal bowel wall enhancement, and adenopathy was 89%, 79%, and 64%, respectively  The interobserver agreement for these signs varied between 0.52 and 0.65 for CT enteroclysis MR enteroclysis  Magnetic resonance (MR) enteroclysis has the advantage of a lack of radiation exposure and safe contrast agents  less accurate than CT enteroclysis  Relatively less sensitive  For the same signs, the sensitivity of MR enteroclysis was 60%, 56%, and 14%, respectively  between 0.15 and 0.48 for MR enteroclysis.
  • 161. PET-CT  PET-CT is not first choice, but can be useful if findings on CT or MR are equivocal or to look for metastatic disease.