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Advanced Retinal Diagnostic Imaging Services

Alex Etlin, PhD

Vickie Zhang, PhD(c)

Brandon Lujan, MD

Total Interviews: 101

Luke Lee, MBA
Age-related Macular Degeneration (AMD)
Age-related Macular Degeneration (AMD)

Advanced Form
Age-related Macular Degeneration (AMD)

Early Form

Advanced Form
Age-related Macular Degeneration (AMD)

Early Form

Advanced Form
Total Available Market
$12 billion

Target Market
$120 million
Asymptomatic
individuals over age 60
•Asymptomatic adults don’t care to be imaged
•Most AMD patients would like to be monitored
more frequently
Clinical evidence showing
frequent monitoring results
in better patient outcomes.

Clinicians don’t think they
should pay for our service.
To get and keep patients,
“you have to provide easy
access and financial support
so patients don’t have to pay.”

Then patients would
want to show up
We learned:
Customer segments

What do they want?

Asymptomatic individuals
Patients

Would like to be monitored frequently
Prefer easy access to care
Some are willing to pay

Clinicians

Want to see clinical evidence
Do not want to pay

Who should be our payers?
Insurance companies? Pharma companies?
•Clinical evidence that frequent
monitoring leads to better patient
outcomes
•Frequent monitoring would
reduce overall healthcare costs!
Validation: Early detection of disease
progression => decrease cost of
treatments

CLINICAL TRIAL
What does industry say?
Industry: Overwhelmed by Data
“We Need insight from

existing clinical data”
To better design what is
coming next:

Who to include?
What endpoints?
ARDIS: Value-added Analysis
Where do we go from here?

1. Already submitted three analysis proposals
2. How can we build value using other’s data?

3. Perform our own trial and protect insights
Pilot Clinical Data:
Frequent Monitoring Matters

San Francisco VA Medical Center
Investment Readiness

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Ardis final

Notas del editor

  1. We interviewed over 30 asymptomatic older adults & AMD patients. We found out asymptomatic adults don’t care to be imaged, while AMD patients feel they are not being adequately monitored, and would like to be monitored more often.(25 sec)
  2. We interview about 40 clinicians (2sec)
  3. We learn that to convince clinicians to refer patients to our service, we first must demonstrate that frequent monitoring would result in better patient outcomes. They want to see clinical evidence in the form of publications. Also, we found out clinicians can be users, but they would not want to pay.(25 sec)
  4. Dr. Lillie Mosddegh said she would refer patients to us if we can show clinical evidence. She also taught us how to get and keep patients. We have to provide easy access since AMD patients are older and often not independent. Also, we should provide financial support to they don’t have to pay out of pocket. Once we cover these 2 key issues, we should be able to get high compliance rate.(27sec)
  5. Base on our interviews, we crossed out asymptomatic individuals. We learned patients do have the needs to be monitored more often, and easy access to get to care. However, only some are willing to pay out of pocket. Clinicians would be on board once they see clinical evidence that our service can improve patient outcomes. However, they don’t think they should be paying for it. To figure out who should be our payers, we turned to insurance companies and pharma companies. (27sec)
  6. We then spoke to insurance reimbursement experts. And found in order to convince insurance companies to cover our service, we must first provide evidence that frequent monitoring lead to better patient outcomes, just like clinicians. Second, we have to show our service reduces overall healthcare cost. Because after all, they are in a business. We believe we our service does reduce healthcare costs. Because cost of treatments would decrease with early detection of disease progression. And treatments in the form of injections can be very expensive for advanced AMD. Of course, we have to conduct a clinical trial to demonstrate that.(~3 min)