9. Difference between Benign and Malignant Tumors Cause death unless removed surgically before metastasis 9. Not cause death except when located in areas producing pressure and obstruction. Produce typical cancer cachexia 8. Not produce typical cachexia Extensive tissue destruction as a result of infiltration 7. produce minimal tissue destruction Do not resemble normal tissue 6. Cells resemble those normal tissue from which they arise Tends to recur after surgical removal. 5. Do not tend to recur when removed surgically Spread via lymph stream and blood 4. Do not spread but remain localized Infiltrate surrounding tissues tumor extended in all directions. Poorly differentiated from normal tissue 3. Grow to expansion; do not infiltrate surrounding tissues Rarely encapsulated 2. Usually encapsulated Grows rapidly 1. Grows slowly Malignant Benign