"Sickle cell anemia is a genetic blood disorder that affects the shape of red blood cells. Instead of being round and flexible, the red blood cells become crescent-shaped and rigid. This can cause them to get stuck in blood vessels, leading to pain, organ damage, and other complications. Sickle cell anemia is more common in people of African, Mediterranean, Middle Eastern, and Indian descent. It's important to raise awareness about this condition and support those affected by it."
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Oral Health & Sickle Cell anaemia .pptx
1. Introduction to Sickle
Cell Anemia
Sickle cell anemia is a genetic blood disorder that affects the hemoglobin
molecule. It causes red blood cells to become stiff, sticky, and form a
crescent or sickle shape.
by Asjad Malik
2. Understanding the Meaning of Sickle
Cell Anemia
1 Genetic Mutation
The development of sickle cell
anemia is linked to a mutation in the
hemoglobin gene.
2 Hemoglobin Abnormalities
The abnormal hemoglobin can lead
to reduced oxygen flow, causing
various health complications.
3 Inheritance Pattern
Sickle cell anemia is inherited in an autosomal recessive pattern.
3. Symptoms and Signs of Sickle Cell
Anemia
Chronic Pain
Patients experience recurrent episodes of
severe pain due to blocked blood flow.
Organ Damage
Damage to various organs is common, including
the liver, spleen, and kidneys.
Anemia
Low red blood cell count often leads to fatigue
and reduced energy levels.
Jaundice
Yellowing of the skin and eyes is a characteristic
sign of sickle cell anemia.
4. Diagnosis of Sickle Cell Anemia
Blood Test
Diagnostic tests include hemoglobin
electrophoresis and a complete blood count.
Microscopic Examination
Microscopic analysis of blood smears can reveal
the presence of sickle cells.
5. Treatment Options for Sickle Cell Anemia
1
Hydroxyurea
A medication that can reduce the
frequency of pain crises and
hospitalizations. 2 Bone Marrow Transplant
An option for severe cases, but it
carries significant risks and
complications.
3
Blood Transfusions
May alleviate symptoms and provide
relief from anemia and pain.
6. Complications Associated with Sickle Cell
Anemia
1 Stroke
Individuals with sickle
cell anemia are at an
increased risk of stroke.
2 Infections
Reduced immunity leads
to a higher susceptibility
to infections.
3 Vision Problems
Retinal damage and
vision impairment are
potential complications.
7. Pictures and Illustrations of Sickle Cell
Anemia
Laboratory Diagnosis
Microscopic examination of
blood smears for the presence
of sickle-shaped cells.
Blood Transfusions
Image depicting a patient
receiving a blood transfusion
for sickle cell anemia.
Medication and
Treatment
Visual representation of
medication used in the
treatment of sickle cell anemia.
8. Conclusion and Key Takeaways
Genetic Basis
Sickle cell anemia is
caused by a genetic
mutation affecting
hemoglobin.
Chronic Health
Condition
It requires long-term
management and regular
medical care.
Supportive Care
Psychosocial support and
multidisciplinary care are
essential for patients.