A brief description on Pharmaceutical automation, with purpose it's advantages and disadvantages and it's benefits in tablet manufacturing, packaging.

1. PRESENTED TO PRESENTED BY
Dr.Anjali Sharma Urvashi Saini
(Associate Proff. ) M.pharma(M-410)
GURU GOBIND SINGH COLLEGE OF PHARMACY
YAMUNA NAGAR

2.  Pharmaceutical Automation is considered to be a technology for
designing, analyzing, and controlling manufacturing through
timely measurements (i.e., during processing) of critical quality
and performance attributes of raw and in-process materials.
Automation-
 Means the use of machines and the equipment for the performing
physical and mental operation in a production processing place
of human being.
 It is a system of doing work where material handling, production
process and product design are integrated through mechanism of
thoughts and effort to achieve a set regulating and control
system.

3.  It is the result of industrialization, driven by the need to
increase productivity and to archive consisting quality
product and processes with the goal of ensuring final
product quality.
 It can be done various levels of manufacturing system
1. Handling of raw materials , semi-finished goods and
finished goods
2. During the production process(efficient machine are used)
3. In inspection and quality control operation
Purpose of Automation
1. To increase productivity
2. Reliving from heavy work load
3. Improve quality of products and reduce waste
4. For safe handling of hazardous substances
5. To reduce the cost

4. 1. It provides better quality of goods and service.
2. It minimizes the total cost ,in direct labor cost.
3. It provides effective control in operation.
4. Greater accuracy, more output and greater speed are
induced.
5. It can improve a better working condition.
6. Safety of workers is improved.
7. Minimal of wastage is done.
8. The quality of product improves as human input is
minimized.

5. 1. Huge capital investment is required.
2. The maintenance cost is very high because
maintenance labor of high caliber is required.
3. It can create unemployment.
4. Continuous power supply is required.
5. Large inventories are required
6. Any breakdown, anywhere lead to the complete
breakdown.
7. There are restrictions in designing and construction of
the building.

6. Benefits of automation in tablet production
1. Improve material handling.
2. Improve specific unit operation-Unit operations in tablet manufacturing:-
 Particle size reduction
 Sieving
 Mixing
 Particle size enlargement
 Drying
 Compression
 Sorting
 Coating
 Packaging.
3.Eliminate or combine processing steps.
4. Incorporate automated process control of unit operation and processes.

7. Pharmaceutical packaging
 Pharmaceutical packaging is the combination of
components necessary to contain, preserve, protect and
deliver a safe, efficacious drug product.
 Functionally the packaging of pharmaceuticals involves
containment as well as protection from damaging
environmental factors such as moisture, oxygen,
temperature and light
 In packaging system automation should include bottle
orientation, capping, labeling and collation.
 Automation of packaging will also require a system for
monitoring the operation that will cover a no of
supervisory function, e.g. checking for low hopper level,
fallen bottles, low-level supply and its routine function.

8. New Types of Equipment And Technologies In Automation Of Packaging
Systems.
 Bar code tracking
 Robotics
 Machine vision
 Laser printing

9. 1. Internal packaging machine control only( no integration)
2. Electrical interlocking of packaging machine
3. Packaging equipment performance monitoring
4. Product to package verification
5. Machine readable code / text to product/package
verification
6. Manufacturing work order input from MEC or ERP
Automation in laboratory procedures
Analytical procedures can be divided into three stages-
1. Sample preparation
2. Qualitative or quantitative measurement
3. Data reduction