This Edureka Blockchain 101 Training will give you a complete fundamental understanding regrading Blockchain and Bitcoin. You will learn following topics:
1. What is Blockchain?
2. Blockchain concepts
3. Hyperledger
4. Blockchain Use Case
5. Blockchain in the Industry
6. Solidity programming
7. Demo: Smart Contracts
***** Blockchain Training : https://www.edureka.co/blockchain-training *****
This Edureka video on "Blockchain Explained" is to guide you through the fundamentals of the new revolutionary technology called Blockchain and its defining concepts. Below are the topics covered in this tutorial:
1. History of blockchain
2. What is Blockchain
3. Traditional Transaction vs Blockchain
4. How Blockchain Works
5. Benefits of Blockchain
6. Blockchain Transaction Demo
Here is the link to the Blockchain blog series: https://goo.gl/DPoAHR
You can also refer this playlist on Blockchain: https://goo.gl/V5iayd
A Decentralized Autonomous Organization is governed by a set of software rules enacted by smart contracts on a blockchain. Potential use-cases are presented, as well as current applications of the technologies. DAOs promise to enable novel decision-making processes in an organization, innovate the current business models, and create new ones.
This Edureka Blockchain technology tutorial will give you an understanding of how blockchain works and what are blockchain technologies. This tutorial helps you to learn following topics:
1. What are Blockchain & Bitcoin
2. Blockchain Technologies
3. Peer to Peer Network
4. Cryptography
5. Proof of Work & Blockchain Program
6. Ethereum & Smart Contracts
7. Blockchain Applications and Use Cases
The document provides an overview of the Web3 incubator/accelerator landscape, including both Web3 native programs and traditional programs. It compares various incubator programs on their structure (batch-based vs rolling intake), partner ecosystems, economics, mentors and strengths. It then highlights Alpha Incubate, a Web3 native incubator that takes a bespoke, rolling approach working closely with startups on product development, fundraising and leveraging the Alpha network community.
STATE OF THE PLATFORM REVOLUTION 2021 - by Sangeet Paul ChoudarySangeet Paul Choudary
This 90-page report lays out the key themes in the platform economy for the year 2020-21. Themes span platform regulation, inequality in the gig economy, platform strategy for incumbents, bigtech movements into new industries etc.
This Edureka Blockchain 101 Training will give you a complete fundamental understanding regrading Blockchain and Bitcoin. You will learn following topics:
1. What is Blockchain?
2. Blockchain concepts
3. Hyperledger
4. Blockchain Use Case
5. Blockchain in the Industry
6. Solidity programming
7. Demo: Smart Contracts
***** Blockchain Training : https://www.edureka.co/blockchain-training *****
This Edureka video on "Blockchain Explained" is to guide you through the fundamentals of the new revolutionary technology called Blockchain and its defining concepts. Below are the topics covered in this tutorial:
1. History of blockchain
2. What is Blockchain
3. Traditional Transaction vs Blockchain
4. How Blockchain Works
5. Benefits of Blockchain
6. Blockchain Transaction Demo
Here is the link to the Blockchain blog series: https://goo.gl/DPoAHR
You can also refer this playlist on Blockchain: https://goo.gl/V5iayd
A Decentralized Autonomous Organization is governed by a set of software rules enacted by smart contracts on a blockchain. Potential use-cases are presented, as well as current applications of the technologies. DAOs promise to enable novel decision-making processes in an organization, innovate the current business models, and create new ones.
This Edureka Blockchain technology tutorial will give you an understanding of how blockchain works and what are blockchain technologies. This tutorial helps you to learn following topics:
1. What are Blockchain & Bitcoin
2. Blockchain Technologies
3. Peer to Peer Network
4. Cryptography
5. Proof of Work & Blockchain Program
6. Ethereum & Smart Contracts
7. Blockchain Applications and Use Cases
The document provides an overview of the Web3 incubator/accelerator landscape, including both Web3 native programs and traditional programs. It compares various incubator programs on their structure (batch-based vs rolling intake), partner ecosystems, economics, mentors and strengths. It then highlights Alpha Incubate, a Web3 native incubator that takes a bespoke, rolling approach working closely with startups on product development, fundraising and leveraging the Alpha network community.
STATE OF THE PLATFORM REVOLUTION 2021 - by Sangeet Paul ChoudarySangeet Paul Choudary
This 90-page report lays out the key themes in the platform economy for the year 2020-21. Themes span platform regulation, inequality in the gig economy, platform strategy for incumbents, bigtech movements into new industries etc.
Merge is a mobile application that combines all of a user's credit cards and selects the optimal card for each purchase to maximize rewards. It does this by taking in a user's credit cards, representing them as a single "Merge Card" that can be used for mobile payments. When a purchase is made, Merge's algorithm calculates the potential rewards for each card and automatically selects the one that yields the highest rewards or best promotes the user's credit score. This ensures users are getting the maximum value from their credit cards and taking advantage of all cash back opportunities.
This document discusses how blockchain technology could be used to transform finance by enabling the transfer of various financial assets like stocks, bonds, and derivatives on distributed ledgers. It notes that permissioned blockchains that allow legally accountable validators may be better suited than permissionless ones for governing off-chain assets by providing settlement finality without reversals. Smart contracts could potentially replace financial intermediaries like clearing houses by enabling direct peer-to-peer exchange of assets between buyers and sellers.
The document provides an overview of key concepts related to Web3 including blockchain, distributed systems, benefits and downsides. It discusses non-fungible tokens (NFTs) including what they are, examples, and risks of regular databases. Decentralized autonomous organizations (DAOs) are introduced as organizations implemented as smart contracts on blockchain with examples given. Various tools for building DAOs are also outlined. The metaverse and how virtual worlds and games are evolving with NFTs is briefly explored.
(Pitch Deck): How FTX raised over $1 billionPitch Decks
FTX is a leading cryptocurrency exchange that was launched after its founders realized they could build a better exchange than existing options. It has since grown rapidly, acquiring Blockfolio in 2019 and expanding its product offerings. As of early 2021, FTX had over 1 million daily active users, $14.7 billion in average daily volume, and was the largest cryptocurrency exchange outside of China.
Blockchain technology allows for transparent and secure transactions without an intermediary. It has various applications including financial services, smart contracts, IoT, and more. Key benefits are security, transparency, low costs, and reduced time. Blockchain functions by recording transactions in blocks that are linked using cryptography. Programming languages like Java and frameworks like Ethereum and Hyperledger can be used to develop blockchain applications. Databases can also integrate blockchain features to provide a scalable solution for deploying blockchain proofs-of-concept, platforms and applications.
This slides were presented at IEEE APSIT Student Branch Online Webinar held on 24 April 2020. Recording of the webinar can be seen here https://www.youtube.com/watch?v=CJCvlZ3Mjh4
Blockchain Training | Blockchain Tutorial for Beginners | Blockchain Technolo...Edureka!
This Edureka Blockchain training will give you a fundamental understanding regrading Blockchain and Bitcoin.
This session will help you learn following topics:
1. Current Existing Monetary System
2. How can Blockchain and Bitcoin help?
3. What is Blockchain?
4. Blockchain concepts
5. Bitcoin Transaction
6. Blockchain features
7. Blockchain Use Case
8. Demo: Bitcoin Transaction
The document outlines plans to launch a wholesale banking platform called Standard Treasury that will provide banking services via API to fintech companies and power the next generation of financial applications. It details the team's experience in banking technology, regulatory work completed in the UK and US, product roadmap, and financial projections showing an $8.99M series A round will fund the application and launch process. Risks are acknowledged but mitigation strategies are proposed to address challenges in obtaining a banking license, timeline, and hiring.
Rather than trying to scale up blockchain technology, BigchainDB starts with a big data distributed database and then adds blockchain characteristics - decentralized control, immutability and the transfer of digital assets.
This document provides an overview of Bitcoin and blockchains. It discusses what a blockchain is and provides a live online demo. It covers Bitcoin's history and evolution, addresses whether Bitcoin has any real value beyond speculation, and examines its price history. Risks of Bitcoin like scams and money laundering are outlined. Ethereum and smart contracts are introduced. Issues like the DAO hack and Bitcoin's environmental impact are also summarized. Applications of blockchain technology beyond cryptocurrency like blockchain voting are presented.
A simple interactive ppt on the basics of Blockchain.
What is Blockchain? Why we need it? How it works? Advantages & Disadvantages and many more topics like this.
Future of AI: Blockchain & Deep LearningMelanie Swan
Future of AI: intelligence “baked in” to smart networks, blockchains to confirm authenticity and transfer value, and Deep Learning algorithms for predictive identification. This talk presents two high-impact contemporary emerging technologies: big data and deep learning algorithms, and blockchain distributed ledgers, and discusses their implications for the future of artificial intelligence.
Polygon Presents "DeFi For All: Build DeFi For Mass Adoption"XendFinance
The document provides an overview of Polygon, a scaling solution for Ethereum. Some key points:
- Polygon has over 1000 DApps deployed and 500+ in development, making it the most adopted scaling solution after Ethereum.
- It discusses the importance of composability in the DeFi ecosystem, allowing protocols to build on top of each other.
- Polygon is focused on building technologies like zero-knowledge proofs and rollups to scale Ethereum and enable privacy in DeFi.
What are crypto wallets? How different are they from exchanges? What is their job to be done? where are they weak? What is the potential and future they hold
Brought to you by @ZenGo
Blockchain and cryptocurrencies are emerging technologies that are still not fully understood. There are differing views on their value. Blockchain is a distributed digital ledger of transactions that is replicated across multiple computers. Cryptocurrencies like Bitcoin use blockchain technology, and their value comes from factors like production costs, scarcity, and utility. Ethereum enables decentralized applications and smart contracts through its cryptocurrency Ether. Altcoins have proliferated since Bitcoin, with some gaining significant value through network effects. Initial coin offerings have also raised billions for new blockchain projects.
A presentation explaining the concepts of Blockchain. It covers the introduction to blockchain, types of blockchain, process of adding blocks in bitcoin blockchain, hyperledger block structure, use cases of blockchain explained.
Blockchain is a specific type of database where information is collected in blocks that are chained together, forming a chain of data known as the "blockchain." Each new block of information contains a reference to the previous block, linking them together in a way that makes tampering very difficult. Transactions are transmitted across a peer-to-peer network of computers, validated through solving equations, and collected into blocks that are added to the blockchain, forming a permanent record of all transactions.
Y Combinator pitch deck designed by Zlides
Want to create a pitch deck that inspires your audience? Get your FREE presentation kit designed by Zlides: http://bit.ly/slideshare_zlides
There is no point in drawing a distinction between the future of technology and the future of mobile. They are the same. In other words, technology is now outgrowing the tech industry.
by Benedict Evans. Please see this link for full description, slides, AND version with talk track: http://a16z.com/2016/12/09/mobile-is-eating-the-world-outlook-2017/
Merge is a mobile application that combines all of a user's credit cards and selects the optimal card for each purchase to maximize rewards. It does this by taking in a user's credit cards, representing them as a single "Merge Card" that can be used for mobile payments. When a purchase is made, Merge's algorithm calculates the potential rewards for each card and automatically selects the one that yields the highest rewards or best promotes the user's credit score. This ensures users are getting the maximum value from their credit cards and taking advantage of all cash back opportunities.
This document discusses how blockchain technology could be used to transform finance by enabling the transfer of various financial assets like stocks, bonds, and derivatives on distributed ledgers. It notes that permissioned blockchains that allow legally accountable validators may be better suited than permissionless ones for governing off-chain assets by providing settlement finality without reversals. Smart contracts could potentially replace financial intermediaries like clearing houses by enabling direct peer-to-peer exchange of assets between buyers and sellers.
The document provides an overview of key concepts related to Web3 including blockchain, distributed systems, benefits and downsides. It discusses non-fungible tokens (NFTs) including what they are, examples, and risks of regular databases. Decentralized autonomous organizations (DAOs) are introduced as organizations implemented as smart contracts on blockchain with examples given. Various tools for building DAOs are also outlined. The metaverse and how virtual worlds and games are evolving with NFTs is briefly explored.
(Pitch Deck): How FTX raised over $1 billionPitch Decks
FTX is a leading cryptocurrency exchange that was launched after its founders realized they could build a better exchange than existing options. It has since grown rapidly, acquiring Blockfolio in 2019 and expanding its product offerings. As of early 2021, FTX had over 1 million daily active users, $14.7 billion in average daily volume, and was the largest cryptocurrency exchange outside of China.
Blockchain technology allows for transparent and secure transactions without an intermediary. It has various applications including financial services, smart contracts, IoT, and more. Key benefits are security, transparency, low costs, and reduced time. Blockchain functions by recording transactions in blocks that are linked using cryptography. Programming languages like Java and frameworks like Ethereum and Hyperledger can be used to develop blockchain applications. Databases can also integrate blockchain features to provide a scalable solution for deploying blockchain proofs-of-concept, platforms and applications.
This slides were presented at IEEE APSIT Student Branch Online Webinar held on 24 April 2020. Recording of the webinar can be seen here https://www.youtube.com/watch?v=CJCvlZ3Mjh4
Blockchain Training | Blockchain Tutorial for Beginners | Blockchain Technolo...Edureka!
This Edureka Blockchain training will give you a fundamental understanding regrading Blockchain and Bitcoin.
This session will help you learn following topics:
1. Current Existing Monetary System
2. How can Blockchain and Bitcoin help?
3. What is Blockchain?
4. Blockchain concepts
5. Bitcoin Transaction
6. Blockchain features
7. Blockchain Use Case
8. Demo: Bitcoin Transaction
The document outlines plans to launch a wholesale banking platform called Standard Treasury that will provide banking services via API to fintech companies and power the next generation of financial applications. It details the team's experience in banking technology, regulatory work completed in the UK and US, product roadmap, and financial projections showing an $8.99M series A round will fund the application and launch process. Risks are acknowledged but mitigation strategies are proposed to address challenges in obtaining a banking license, timeline, and hiring.
Rather than trying to scale up blockchain technology, BigchainDB starts with a big data distributed database and then adds blockchain characteristics - decentralized control, immutability and the transfer of digital assets.
This document provides an overview of Bitcoin and blockchains. It discusses what a blockchain is and provides a live online demo. It covers Bitcoin's history and evolution, addresses whether Bitcoin has any real value beyond speculation, and examines its price history. Risks of Bitcoin like scams and money laundering are outlined. Ethereum and smart contracts are introduced. Issues like the DAO hack and Bitcoin's environmental impact are also summarized. Applications of blockchain technology beyond cryptocurrency like blockchain voting are presented.
A simple interactive ppt on the basics of Blockchain.
What is Blockchain? Why we need it? How it works? Advantages & Disadvantages and many more topics like this.
Future of AI: Blockchain & Deep LearningMelanie Swan
Future of AI: intelligence “baked in” to smart networks, blockchains to confirm authenticity and transfer value, and Deep Learning algorithms for predictive identification. This talk presents two high-impact contemporary emerging technologies: big data and deep learning algorithms, and blockchain distributed ledgers, and discusses their implications for the future of artificial intelligence.
Polygon Presents "DeFi For All: Build DeFi For Mass Adoption"XendFinance
The document provides an overview of Polygon, a scaling solution for Ethereum. Some key points:
- Polygon has over 1000 DApps deployed and 500+ in development, making it the most adopted scaling solution after Ethereum.
- It discusses the importance of composability in the DeFi ecosystem, allowing protocols to build on top of each other.
- Polygon is focused on building technologies like zero-knowledge proofs and rollups to scale Ethereum and enable privacy in DeFi.
What are crypto wallets? How different are they from exchanges? What is their job to be done? where are they weak? What is the potential and future they hold
Brought to you by @ZenGo
Blockchain and cryptocurrencies are emerging technologies that are still not fully understood. There are differing views on their value. Blockchain is a distributed digital ledger of transactions that is replicated across multiple computers. Cryptocurrencies like Bitcoin use blockchain technology, and their value comes from factors like production costs, scarcity, and utility. Ethereum enables decentralized applications and smart contracts through its cryptocurrency Ether. Altcoins have proliferated since Bitcoin, with some gaining significant value through network effects. Initial coin offerings have also raised billions for new blockchain projects.
A presentation explaining the concepts of Blockchain. It covers the introduction to blockchain, types of blockchain, process of adding blocks in bitcoin blockchain, hyperledger block structure, use cases of blockchain explained.
Blockchain is a specific type of database where information is collected in blocks that are chained together, forming a chain of data known as the "blockchain." Each new block of information contains a reference to the previous block, linking them together in a way that makes tampering very difficult. Transactions are transmitted across a peer-to-peer network of computers, validated through solving equations, and collected into blocks that are added to the blockchain, forming a permanent record of all transactions.
Y Combinator pitch deck designed by Zlides
Want to create a pitch deck that inspires your audience? Get your FREE presentation kit designed by Zlides: http://bit.ly/slideshare_zlides
There is no point in drawing a distinction between the future of technology and the future of mobile. They are the same. In other words, technology is now outgrowing the tech industry.
by Benedict Evans. Please see this link for full description, slides, AND version with talk track: http://a16z.com/2016/12/09/mobile-is-eating-the-world-outlook-2017/
Network effects. It’s one of the most important concepts for business in general and especially for tech businesses, as it’s the key dynamic behind many successful software-based companies. Understanding network effects not only helps build better products, but it helps build moats and protect software companies against competitors’ eating away at their margins.
Yet what IS a network effect? How do we untangle the nuances of 'network effects' with 'marketplaces' and 'platforms'? What’s the difference between network effects, virality, supply-side economies of scale? And how do we know a company has network effects?
Most importantly, what questions can entrepreneurs and product managers ask to counter the wishful thinking and sometimes faulty assumption behind the belief that “if we build it, they will come” … and instead go about more deterministically creating network effects in their business? Because it's not a winner-take-all market by accident.
Looking to scale something up? Depending on how you're going after your market/ acquiring users, you may need to build a sales organization that's optimized for a top-down or bottom-up sales process (or perhaps both).
Watch the video overview at http://a16z.com/2015/03/06/go-to-market-bootcamp/ and then check out this slide deck, which shares some concrete tips and tools for accelerating time to market -- from the go-to-market experts at a16z, led by 'sales savant' Mark Cranney.
Because selling to enterprises is a lot like getting a bill passed through Congress: it can get stuck. And getting stuck -- or going down the wrong path -- can mean death to startups in a competitive market. Here's how to avoid that.
In this update of his past presentations on Mobile Eating the World -- delivered most recently at The Guardian's Changing Media Summit -- a16z’s Benedict Evans takes us through how technology is universal through mobile. How mobile is not a subset of the internet anymore. And how mobile (and accompanying trends of cloud and AI) is also driving new productivity tools.
In fact, mobile -- which encompasses everything from drones to cars -- is everything.
We’ve shared a lot of data about whether and why ‘this time is different’. But beyond that, why is the tech market opportunity larger than any time in history (no, really!)? One word: mobile.
In this update of his past presentation on Mobile Eating the World — delivered this month at Andreessen Horowitz’ annual investor meeting — a16z’s Benedict Evans shares just how and why mobile changes everything. Because tech is outgrowing the tech industry.
Venture capitalists, especially those investing at the early stage, could be described as “relationship capitalists”. You’ll often hear how investors approach their commitments like a marriage, and that they think long and hard about with whom they want to go to bed. Avoid picturing that second part.
But the VC mystique can be inexplicable at times. Why do they send such curt emails? What the #%$! do they mean by “traction”? Are they even paying attention?!
Here are some things they might be thinking (but probably won’t flat-out say) during the courtship process, and how you can prepare, take ownership, and rock the pitch.
The presentation summarizes TRC's business and financial performance. TRC provides engineering, consulting and construction management services to the energy, environmental and infrastructure industries. It has transformed its business through acquisitions, cost reductions and a focus on higher-growth markets. TRC has a diversified revenue base across business segments and clients. It is pursuing organic growth and acquisitions in the utility/power and oil & gas industries. TRC has strengthened its balance sheet and is demonstrating improved financial metrics as it leverages its business model.
SpringOwl's 99 Page Presentation On Turning Around ViacomEric Jackson
In this 99 page presentation, we lay out why Viacom's stock price has been cut in half in the past year, and our proposed plan for turning the company around.
Houlihan Lokey: Valuation in the Delaware CourtsHoulihan Lokey
This document summarizes a panel discussion on valuation issues in Delaware courts. The panel discusses recent developments in valuation methodologies, appraisal proceedings, and fiduciary duty litigation where valuation is at issue. The key points are:
1) The Delaware courts, through appraisal cases, provide guidance on acceptable valuation methodologies such as discounted cash flow analysis and give preferences to certain inputs like using management projections.
2) Appraisal proceedings determine "fair value" owed to shareholders for their shares, excluding any value related to a merger. Fiduciary duty cases may also involve assessing fair value.
3) Recent cases have given more weight to third-party sales values as evidence of fair value when the sales process
Black Box Thinking - The Surprising Truth About SuccessMatthew Syed
In his new book Black Box Thinking, award winning journalist and best-selling author Matthew Syed shares the surprising truth about success (and why some people never learn from their mistakes).
Covering topics including marginal gains, closed loops, blame culture, the logic of failure and creating a growth culture, Matthew uses gripping case studies, exclusive interviews and really practical takeaways to explain how you can turn failure into success.
Whether developing a new product, honing a core skill or just trying to get a critical decision right, Black Box Thinkers aren't afraid to face up to mistakes. In fact, Black Box Thinkers see failure as the very best way to learn. Rather than denying their mistakes, blaming others or attempting to spin their way out of trouble, these institutions and individuals interrogate errors as part of their future strategy for success.
This is a visual preview of Black Box Thinking. You can pick up a copy of the book at www.mathewsyed.com/blackboxthinking
Why Boards Matter: Building and Developing a World Class Board of DirectorsJim Citrin
Our insights about the market for board talent across S&P 500, the U.S. Tech Industry, and early stage growth companies as well as a cross section of boards interested executives based on the Spencer Stuart Board Index, the U.S. Tech Board Index, and a SurveyMonkey survey put together as input for #WhyBoardsMatter, a joint presentation from Spencer Stuart and Kleiner Perkins.
Read the full post here:
SpringOwl's 99 Page Presentation On How To Best Turnaround Yahoo!Eric Jackson
On Dec. 13, 2015, SpringOwl released this 99 page presentation on why Yahoo needs substantial change from the status quo and why it would be a mistake to sell the core business now at the lows. We offer our 9 point plan for how to turn around the company and create the most amount of value with the least risk for shareholders (and employees)
GP Bullhound LLP puts together its annual report on valuations, revenues and "unicorns" inside the European Union (this is the final list in which UK based companies are being counted as European!)
Top 10 Learnings Growing to (Almost) $10 Million ARR: Leo's presentation at S...Buffer
Our COO Leo Widrich spoke at the SaaStr Annual conference on February 9, 2016 and shared some lessons that have helped Buffer grow. The tips range across product, marketing, and general work culture!
We’re Leaking, and Everything’s Fine: How and Why Companies Deliberately Leak...Ian McCarthy
Although the protection of secrets is often vital to the survival of organizations, at other times organizations can benefit by deliberately leaking secrets to outsiders. We explore how and why this is the case. We identify two dimensions of leaks: (1) whether the information in the leak is factual or concocted, and (2) whether leaks are conducted overtly or covertly. Using these two dimensions, we identify four types of leaks, which we term informing, dissembling, misdirecting, and provoking. We also provide a framework to help managers decide whether or not they should leak secrets.
The new new competition - How digital platforms change competitive strategyPlatform Revolution
The document discusses how platform competition differs from traditional competition. Platform competition occurs at three levels: between platforms, platforms and their partners, and partners within a platform's ecosystem. Platforms win by owning their ecosystem, monitoring it for valuable resources, leveraging user data, acquiring companies built on their platform, monitoring adjacent areas, and having superior technological design. Some markets become "winner-take-all" where network effects drive users to a single dominant platform. Understanding platform competition is important for both platforms and participants in their ecosystems.
Bio-Electronics, Bio-Sensors, Smart Phones, and Health CareJeffrey Funk
Improvements in ICs, MEMS, bio-electronic ICs, and other electronics are enabling a wide range of new solutions for health care. So-called lab-on-a-chip can sense and process many types of biological data and thus help monitor health. Smart phones are becoming an important part of this process as attachments for phones proliferate. Big data services will be necessary to benefit from these new devices.
Perspectives on Innovation Competitiveness in Chemical IndustryLin Haiqiu
This document provides perspectives on innovation and competitiveness in the chemical industry from Dr. Otto C C Lin. It discusses how the key factors of production have evolved from capital and resources to include technology, innovation capabilities, and entrepreneurial spirit. Examples are given of how large chemical companies have changed or disappeared over time. Trends in manufacturing technologies and the evolution of the chemical engineering field are summarized. Finally, factors for success in new business models and competitive business innovations are outlined.
Life Sciences De-Mystified - Mark Bünger - PICNIC '10PICNIC Festival
This document provides an overview of synthetic biology and its potential applications presented by Mark Bünger of Lux Research. It begins with a brief introduction of Lux Research and their focus on emerging technologies. It then provides a high-level introduction to biology, including DNA, proteins, and how cells communicate. Applications of synthetic biology discussed include using biomass to replace petroleum products, standardizing biological parts for predictable circuits, and rapidly declining DNA sequencing costs enabling new products. Corporations, venture capital investment, and biohackers participating in synthetic biology are also mentioned. The document concludes by discussing participating in shaping the future of this emerging field through learning, action, and teaching.
Leading Molecules to Market - An overview on licensingBananaIP Counsels
Leading Molecules to Market - An overview on licensing
Contact Us for Intellectual Property Services
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An Introduction to Bioinformatics
Drexel University INFO648-900-200915
A Presentation of Health Informatics Group 5
Cecilia Vernes
Joel Abueg
Kadodjomon Yeo
Sharon McDowell Hall
Terrence Hughes
Data Science London - Meetup, 28/05/15Boris Adryan
Slides from my @ds_ldn talk about Ontologies in the Internet of Things. Note that this is a short version of a talk that I presented earlier this month on O'Reilly Webcasts, still viewable for a while at: http://www.oreilly.com/pub/e/3365
The cloud can support real-time insights in the life sciences industry by enabling data from different sources like patients, operations, safety reports, and randomization to be connected in real-time. This allows for real-time insights, risk-based monitoring, and adaptive clinical trials. Technology is transforming drug development by moving from paper-based to mobile and patient-reported outcomes. While the cost to develop new drugs has risen significantly over the years, technology has the potential to impact the future through personalized medicine, improved privacy, and modernized regulation.
Technology Developments for high impact future technologyBrian Wang
The document provides an overview of emerging technologies across several fields including energy, computing, materials science, health and medicine, and space exploration. It discusses various nuclear, solar, wind, and biofuel energy technologies. In computing, it mentions quantum computers, DNA nanotechnology, brain emulation, and programmable matter. It also outlines advances in gene therapy, stem cells, biomakers, and life extension. The document predicts major breakthroughs and the convergence of technologies between 2009-2025 that could have significant worldwide impacts.
The document discusses biobusiness and biosafety, providing definitions and opportunities for biotechnology in developing countries. It examines the market for biobusiness, key opportunity areas, and factors for successful bioenterprise innovation including focusing on high-value opportunities, recognizing that innovation need not have long life cycles, and emphasizing people over technologies. The document also outlines biosafety levels and concepts from containment to facility design to protect laboratory workers and the environment.
BioinformaticsPurpose Bioinformatics is the combination of comp.docxrichardnorman90310
Bioinformatics
Purpose: Bioinformatics is the combination of computer science and biology which used various methods of storing and retrieving the biological data which have pros and cons, scientists are able to discover new information on various diseases, its mutation, it helps in differentiating one organism from another by analyzing their genetic data, biological development and will stop various crimes, disadvantages and develops the algorithm that helps in measuring the sequence similarity.
1. Introduction: Bioinformatics is a field which include molecular biology, statistics, issues, computer problems, and extensive mathematics complex problem. It has two stages deliberately gather various insights from the natural information and to make a computational model. It can be found in the study area of precision and preventive medicine.
0. Background info on of bioinformaticsComment by R Daniel Creider: A, B, C and D are not a part of the introduction. The outline is not organized correctly
0. How to approach bioinformatics?
1. Goals of Bioinformatics
0. Development of efficient algorithms
0. Extension of experimental data by predictions
1. Advantages of bioinformatics
1. World is getting information on new discovery and crimes are prevented
1. Discover new information on various diseases
1. How organisms mutate
1. How it analyses data to differentiate one organism from another
1. Disadvantages of bioinformatics
2. Data manipulation, complexity, lack of well-trained manpower to use the software
2. Misuse of the information
0. Problems behinds it
0. Data about the genetic information lack proper analyzed
0. Importance of Bioinformatics
3. Genetic research
0. Genomics and proteomics
1.
Solution
of the problem
1. Use software wisely
1. Decrease its complexity
1. Future of the bioinformatics
2. Bioinformatics is the present and future of biotechnology
0. Use for research and exchange information for comparison, storage and analysis
BIOINFORMATICS: A Technical Report
Texas A&M University-Commerce
Bishow KunwarComment by R Daniel Creider: Your name comes before the name of the University.
Abstract
The main aim of Bioinformatics is to improve the various methods of storing, retrieving and organizing the biological data by critically evaluating the data. The effectiveness of bi informatics in the field of genetics and genomics is playing its part in a way that particularly in textual mining of biological development. Bioinformatics is the application which is the mix of two fields (software engineering and science). It is a field that includes different things like sub-atomic science, measurement issues, software engineering issues, and broad arithmetic complex issues.
Keywords; Bioinformatics, Genetic, Genomic, Biological Development
Introduction:
Bioinformatics is the application which is the combination of two fields (computer science and biology). It is a field that involves multiple things like molecular .
BioinformaticsPurpose Bioinformatics is the combination of comp.docxjasoninnes20
Bioinformatics
Purpose: Bioinformatics is the combination of computer science and biology which used various methods of storing and retrieving the biological data which have pros and cons, scientists are able to discover new information on various diseases, its mutation, it helps in differentiating one organism from another by analyzing their genetic data, biological development and will stop various crimes, disadvantages and develops the algorithm that helps in measuring the sequence similarity.
1. Introduction: Bioinformatics is a field which include molecular biology, statistics, issues, computer problems, and extensive mathematics complex problem. It has two stages deliberately gather various insights from the natural information and to make a computational model. It can be found in the study area of precision and preventive medicine.
0. Background info on of bioinformaticsComment by R Daniel Creider: A, B, C and D are not a part of the introduction. The outline is not organized correctly
0. How to approach bioinformatics?
1. Goals of Bioinformatics
0. Development of efficient algorithms
0. Extension of experimental data by predictions
1. Advantages of bioinformatics
1. World is getting information on new discovery and crimes are prevented
1. Discover new information on various diseases
1. How organisms mutate
1. How it analyses data to differentiate one organism from another
1. Disadvantages of bioinformatics
2. Data manipulation, complexity, lack of well-trained manpower to use the software
2. Misuse of the information
0. Problems behinds it
0. Data about the genetic information lack proper analyzed
0. Importance of Bioinformatics
3. Genetic research
0. Genomics and proteomics
1.
Solution
of the problem
1. Use software wisely
1. Decrease its complexity
1. Future of the bioinformatics
2. Bioinformatics is the present and future of biotechnology
0. Use for research and exchange information for comparison, storage and analysis
BIOINFORMATICS: A Technical Report
Texas A&M University-Commerce
Bishow KunwarComment by R Daniel Creider: Your name comes before the name of the University.
Abstract
The main aim of Bioinformatics is to improve the various methods of storing, retrieving and organizing the biological data by critically evaluating the data. The effectiveness of bi informatics in the field of genetics and genomics is playing its part in a way that particularly in textual mining of biological development. Bioinformatics is the application which is the mix of two fields (software engineering and science). It is a field that includes different things like sub-atomic science, measurement issues, software engineering issues, and broad arithmetic complex issues.
Keywords; Bioinformatics, Genetic, Genomic, Biological Development
Introduction:
Bioinformatics is the application which is the combination of two fields (computer science and biology). It is a field that involves multiple things like molecular ...
The document discusses several trends in information technology including:
1) Increased certification standards for business technology teachers and incorporation into teacher education programs.
2) Continued growth in computer processing speed, storage capacity, and internet traffic speed according to Moore's Law.
3) Emerging technologies like digital ink, RFID tags, smart pills, and networked smart objects that will integrate with daily life.
- The document discusses how biomedical research is entering a period of disruption due to factors like big data, digitization, and open science.
- Key points discussed include the history and changing nature of computational biomedicine, implications of large initiatives like the Precision Medicine Initiative, and how funders should respond by encouraging global open science and sharing infrastructure and policies.
- The author advocates for creating a "commons" environment to enable finding and reusing shared digital research objects according to FAIR principles in order to advance open collaborative science.
Biotechnology the next growth area for grassroots entrepreneurship? The Indep...Shiwen Yap
Biohacking, or DIY biology, is an emerging grassroots movement where hobbyists experiment with DNA and biological processes. Using inexpensive DNA parts and open source tools and databases, biohackers can design and assemble genetic components to program cells. While this presents opportunities for innovation, there are also safety and security concerns to consider. Licensing biohackers and providing community labs could help promote safe experimentation while fostering interaction with the commercial biotech industry. Establishing a community biology lab in Singapore may help aggregate local biohackers and support the development of biotech startups.
While many companies are contributing to the battle against the pandemic, Deep Tech startups are trying to overcome scientific challenges to help with prevention, testing or treatment in novel and scalable ways.
This live event organized by SOSV brings together investors who have backed dozens of relevant startups, to get a sense of:
- The variety of solutions being developed,
- Their potential outcomes,
- The broader role and opportunities of deep tech investment.
SPEAKERS
- Seth Bannon, Founding Partner, Fifty Years
- Jun Axup, PhD, Chief Science Officer & Partner, IndieBio / SOSV
- Alex Morgan, MD PhD, Partner, Khosla Ventures
MODERATORS
- Julie Wolf, PhD, Communications Director, IndieBio / SOSV
- Benjamin Joffe, Partner, SOSV
COVID-19 PORTFOLIO
- Fifty Years: www.fifty.vc/covid
- SOSV: www.sosv.com/covid-startups/
- Khosla Ventures: www.khoslaventures.com/khosla-ventures-entrepreneurs-are-responding-with-amazing-diversity-to-covid-19-solutions-for-societys-needs
Intellectual property laws impact consumers in several ways. Stronger copyright and patent laws have led to higher prices and less availability and suitability of goods for consumers. For example, textbooks are expensive for students due to lack of used book markets. Patents on seeds and genes have led to corporate control over food and higher drug prices have made medicines unaffordable. Technological protection measures also restrict lawful consumer uses like format shifting and assistive technologies. Enforcement provisions do not distinguish between commercial piracy and lawful consumer uses, potentially criminalizing normal activities. Advocates argue for balancing intellectual property rules to promote both innovation and access for consumers.
Life Technologies' Journey to the Cloud (ENT208) | AWS re:Invent 2013Amazon Web Services
Life Technologies initially planned to build out its own data center infrastructure, but when a cost analysis revealed that by using Amazon Web Services the company would save $325,000 in hardware alone for a single new initiative, the company decided to use AWS instead. Within 6 months of adopting AWS, Life Technologies launched their Digital Hub platform in production, which now undergirds Life Technologies' entire instrumentation product suite.This immediately began to decrease their time-to-market and enhance their customers' user experience. In this session, we provide an overview of our path to the AWS cloud, with particular focus on the evaluation criteria used to make a cloud vendor decision. We also discuss the lessons learned since going into production.
This document discusses computer and network security and how important it is to secure data and information stored on computers. Everything in modern life relies on computers, so securing data and networks is crucial, just like securing a physical bank with guards and cameras. Employees need to understand cybersecurity risks and procedures to correctly protect networks. Cyber attacks cost US businesses an average of $160,000 per security breach. Strengthening security, authentication, privacy and consumer protection is key to developing a safe information society with user confidence.
Sequencing Genomics:The New Big Data DriverLarry Smarr
1. Genomic sequencing is driving big data as the cost of sequencing DNA falls faster than Moore's Law and the amount of data produced increases dramatically.
2. The Beijing Genome Institute is the world's largest genomic institute, using over 130 sequencing machines each producing 25 gigabases per day for a total of over 12 petabytes of data storage.
3. Interdisciplinary teams of computer scientists, data analysts, and geneticists are needed to analyze the massive amounts of genomic and metagenomic data being produced to gain insights into human health and disease.
ANAMOLOUS SECONDARY GROWTH IN DICOT ROOTS.pptxRASHMI M G
Abnormal or anomalous secondary growth in plants. It defines secondary growth as an increase in plant girth due to vascular cambium or cork cambium. Anomalous secondary growth does not follow the normal pattern of a single vascular cambium producing xylem internally and phloem externally.
ESR spectroscopy in liquid food and beverages.pptxPRIYANKA PATEL
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
The binding of cosmological structures by massless topological defectsSérgio Sacani
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
The debris of the ‘last major merger’ is dynamically youngSérgio Sacani
The Milky Way’s (MW) inner stellar halo contains an [Fe/H]-rich component with highly eccentric orbits, often referred to as the
‘last major merger.’ Hypotheses for the origin of this component include Gaia-Sausage/Enceladus (GSE), where the progenitor
collided with the MW proto-disc 8–11 Gyr ago, and the Virgo Radial Merger (VRM), where the progenitor collided with the
MW disc within the last 3 Gyr. These two scenarios make different predictions about observable structure in local phase space,
because the morphology of debris depends on how long it has had to phase mix. The recently identified phase-space folds in Gaia
DR3 have positive caustic velocities, making them fundamentally different than the phase-mixed chevrons found in simulations
at late times. Roughly 20 per cent of the stars in the prograde local stellar halo are associated with the observed caustics. Based
on a simple phase-mixing model, the observed number of caustics are consistent with a merger that occurred 1–2 Gyr ago.
We also compare the observed phase-space distribution to FIRE-2 Latte simulations of GSE-like mergers, using a quantitative
measurement of phase mixing (2D causticality). The observed local phase-space distribution best matches the simulated data
1–2 Gyr after collision, and certainly not later than 3 Gyr. This is further evidence that the progenitor of the ‘last major merger’
did not collide with the MW proto-disc at early times, as is thought for the GSE, but instead collided with the MW disc within
the last few Gyr, consistent with the body of work surrounding the VRM.
BREEDING METHODS FOR DISEASE RESISTANCE.pptxRASHMI M G
Plant breeding for disease resistance is a strategy to reduce crop losses caused by disease. Plants have an innate immune system that allows them to recognize pathogens and provide resistance. However, breeding for long-lasting resistance often involves combining multiple resistance genes
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
Current Ms word generated power point presentation covers major details about the micronuclei test. It's significance and assays to conduct it. It is used to detect the micronuclei formation inside the cells of nearly every multicellular organism. It's formation takes place during chromosomal sepration at metaphase.
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Phenomics assisted breeding in crop improvementIshaGoswami9
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skills
2. Bio startups that operate like software startups
The emerging macro trend: Bio 2.0
Bio in 2015 is like software in 2005
Software is eating Bio
Cloud biology
emergence of low
CapEx startups
Software at the center
Machine learning,
cloud computing
Minimize FDA Risk
DTC, digital health,
consumer genomics, etc
3. Storage cost-performance and computing cost-performance
Moore’s law: cost of storage, compute ⇒ zero
0.01
0.1
1.
10.
100.
1000.
1994 1996 1998 2000 2002 2004 2006 2008 2010 2012
Dollars($)
Compute cost ($ per 1 million transistors)
Storage cost ($ per gigabyte)
4. Silicon content: $20-22
NAND Flash
$18-20
Display
$15-17
Applications Processor
$8-10
DRAM
$10-13
Baseband
$4-5
RF and FEM
$3-4
Power
Amplifier
$3-4
PMIC
$3-4
Combo-chip
(WIFI/BT/FM)
$3-4
Touch
Controller
$3-4
GPS
$3-4
Image
Sensors
Silicon content: $9-10
Camera Module
$7-11
Touch Panel
$5-6
Battery (Li Polymer)
$3-5
HDI PCB
$1-2
Camera Lens
$2-3
Gyroscope/Accelerometer
$0.70-0.80
Audio
Codecs
$0.50-0.60
Speaker IC
Substrate
$1-2
LCD Drive IC
$0.70-0.80
MEMs Microphone
$1.00-1.50
LCD Drive IC
Moore’s law: cost of storage, compute ⇒ zero
Source: Nomura Securities, Gartner 2013 report.
5. Side benefits of Moore’s law: cost of sensors ⇒ zero
Source: Qualcomm
IntegratedSensors,UserExperiences
Ambient Light
Accelerometer
Magnetometer
Ambient Light
Accelerometer
Magnetometer
Ambient Light
Accelerometer
Magnetometer
Ambient Light
Accelerometer
Magnetometer
Ambient Light
Accelerometer
Magnetometer
Gyroscope
Proximity
Gyroscope
Proximity
Gyroscope
Proximity
Pressure
RGB
Pressure
RGB
Pressure
RGB
Gyroscope
Proximity
Temperature
Humidity
Hall Effect
Temperature
Humidity
Hall Effect
Heart Rate
Fingerprint
2010 2011 2012 2013 2014 2015+
GALAXY 1
GALAXY S2
GALAXY S3
GALAXY S4
GALAXY S5
6. Beyond Moore’s law: cost of sequencing ⇒ zero
Source: Nature, 2014
Cost of genome
sequencing.
Next generation
sequencers enter
the market.
Moore’s law for
computing costs.
The price of
sequencing a whole
human genome hovers
around $5,000 and is
expected to drop even
lower.
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
10,000
1,000
100
10
1
Cost(thousandsUS$)
7. Putting these trends together
This is disrupting traditional biotech
= SOFTWARE IS EATING BIO
Compute Sensors Biology
+ +
8. Bio 2.0 is not Biotech
BIOTECH STARTUPS SOFTWARE STARTUPS
Subject Uncontrollable organisms Perfectly determinate code
Environment Poorly understood, natural Well understood, artificial
Approach Indefinite, random Definite, engineering
Regulation Heavily regulated Basically unregulated
Cost Expensive ( > $1B per drug) Cheap (a little seed money)
Team High-salaried, unaligned lab drones Committed entrepreneurial hackers
& BIO 2.0
From Peter Thiel’s Zero to One
12. Slow and expensive to develop
Toxic side effects
FDA regulated
Traditional therapeutics
IMAGE: Champlax
13. Title Text
Subtitle text
Digital therapeutics for chronic
disease
Mobile enables traction, patient
success, and a new model for
insurance companies
Digital health & digital therapeutics
IMAGE: Omada Health
14. Large capital outlay
Poor reproducibility
Empirically driven
doesn’t scale
The four horsemen of Eroom’s law
Traditional biology
15. Title Text
Subtitle text
Biology that works like programming:
Cloud experiments run through software
Cloud biology
IMAGE: Emerald Therapeutics
18. New a16z fund for Bio 2.0
Vijay Pande new GP:
uniquely suited for Bio 2.0
a16z approach
applied to Bio
Bio 2.0 software +
cloud bio, w/o
traditional FDA risk
20. Vijay Pande:
Bio2.0 background
Chemistry
Camille and Henry Dreyfus Professor, Stanford Univ.
Thomas Kuhn Paradigm Shift Award, American Chemical
Society Teacher-Scholar Award, Dreyfus Foundation
Physics
AB Princeton University, 1992, PhD MIT, 1995 | Michael and
Kate Bárány Award for Young Investigators, Biophysical
Society Fellow, American Physical Society
Computer Science:
Founder, Folding@home Distributed Computing | MIT TR100
Guinness World Record, Folding@home First to a Petaflop
Netxplorateur of the Year
Biology
Chair, Biophysics, Stanford University Medical School
Delano Award for Computational Biosciences, American Soc.
for Biochem. and Molecular Biology | Irving Sigal Young
Investigator Award, Protein Society
21. Title Text
Subtitle text
Crowd sourced computational
biology for biomedicine
Anticipated the future
Cloud before Loudcloud
GPU computing before CUDA
Crowdsourcing before wikipedia
Founding Director, Folding@home
Approximately 2,000,000
people have donated
computer time.
More processing power than
Amazon Web Services,
Guinness World Record
FOLDING@HOME
22. Title Text
Subtitle text
$900M
Next generation approaches to
therapeutics for infectious disease
Computation at its heart
Regulatory Innovations: drug repurposing
Co-founder, Globavir BioSciences
23. Vijay Pande – Bio & IT entrepreneur
ADVISOR TO STARTUPS IN BIO
Acumen Pharmaceuticals (Alzheimer’s
Disease)
Counsyl (Carrier testing)
Globavir (Infectious Disease)
EMPLOYEE #1 AT NAUGHTY DOG
Started at 15 years old
writing computer games
Naughty Dog later
sold to Sony
ADVISOR TO STARTUPS IN IT
Clearspeed (high speed compute hardware)
Discovery Engine (Semantic search)
Numerate (Computational Drug Design)
Omnipod (Software for pharma)
OpenEye (Software for pharma)
Pharmix (Computational Drug Design)
Protein Mechanics (molecular simulation)
Schrodinger (Software for pharma)
Stack IQ (Cloud software stack)
Notas del editor
Powerful new methods put software at the center
Machine Learning, Large-scale data, Cloud computing
Emergence of a “Cloud Bio” infrastructure
Analogs to cloud computing: low CapEx startups in Bio
Approaches that seek to avoid FDA risk
DTC, consumer genomics, etc
Powerful new methods put software at the center
Machine Learning, Large-scale data, Cloud computing
Emergence of a “Cloud Bio” infrastructure
Analogs to cloud computing: low CapEx startups in Bio
Approaches that seek to avoid FDA risk
DTC, consumer genomics, etc
Cloud biology
Biology is following in IT’s footsteps with its own cloud experimental infrastructure
Ecosystem gives ability to startup with minimal investment
Computational medicine
Genomic advances enabling personalized medicine
Machine learning enabling smart drug discovery
Digital Health
Mobile phone and software enabling broad population management tools
Cloud biology
Biology is following in IT’s footsteps with its own cloud experimental infrastructure
Ecosystem gives ability to startup with minimal investment
Computational medicine
Genomic advances enabling personalized medicine
Machine learning enabling smart drug discovery
Digital Health
Mobile phone and software enabling broad population management tools
Software can positively impact our health, wellness, and lives
Mobile leads to more natural human connections, sensors, reminders
Quantified self + Cloud brings everything together
Smartphones enable better population management tools
Smartphones and notifications allow engagement with healthcare apps
Smartphone hardware can be used for diagnostic purposes or to power medical add-ons
Teledermatology use phone camera to send pictures of skin conditions
Decentralization as a general theme
Bringing the patient to the center of the decision making process
Cloud biology
Biology is following in IT’s footsteps with its own cloud experimental infrastructure
Ecosystem gives ability to startup with minimal investment
Computational medicine
Genomic advances enabling personalized medicine
Machine learning enabling smart drug discovery
Digital Health
Mobile phone and software enabling broad population management tools
Hardware: Cloud Experiments
equivalents to data centers for experiments: low startup CapEx
Cloud labs can use commodity hardware from mobile supply chain
Software
Machine Learning/Statistics powerfully complement biology
Open source tools create an established tool chain
People
New generation of students who know biology and can code
Coding is more than programming — it’s the way to break down challenging problems, applicable to biology broadly
Cloud biology
Biology is following in IT’s footsteps with its own cloud experimental infrastructure
Ecosystem gives ability to startup with minimal investment
Computational medicine
Genomic advances enabling personalized medicine
Machine learning enabling smart drug discovery
Digital Health
Mobile phone and software enabling broad population management tools
Consumer: consumer genomics: eg, actionable choices
Clinical
personalized medicine: eg, use genomics to predict the best drugs for cancer patients
advanced computational imaging: eg coupling machine learning with advances in imaging hardware
clinical genomics & testing: eg disrupting existing clinical tests with genomic approaches that are cheaper and open new doors
B2B: new tools to accelerate others, building out the infrastructure
Powerful new methods put software at the center
Machine Learning, Large-scale data, Cloud computing
Emergence of a “Cloud Bio” infrastructure
Analogs to cloud computing: low CapEx startups in Bio
Approaches that seek to avoid FDA risk
DTC, consumer genomics, etc
Software can positively impact our health, wellness, and lives
Mobile leads to more natural human connections, sensors, reminders
Quantified self + Cloud brings everything together
Smartphones enable better population management tools
Smartphones and notifications allow engagement with healthcare apps
Smartphone hardware can be used for diagnostic purposes or to power medical add-ons
Teledermatology use phone camera to send pictures of skin conditions
Decentralization as a general theme
Bringing the patient to the center of the decision making process