Bilirubin estimation

Biochemistry Diploma Students Dr.Ehab Mansoura University Faculty of Science-Damietta Chemistry Department Branch-Biochemistry 2009 For

A. Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object]

B. Formation of bilirubin: ,[object Object],[object Object],[object Object],[object Object],[object Object]

C. Transport of bilirubin in the plasma ,[object Object]

[object Object],[object Object],[object Object],D. Uptake of bilirubin by the liver

E. Secretion of bilirubin into bile ,[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],F. Formation of urobilin in the intestine

[object Object],[object Object],[object Object],G. Excretion of urobilinogens in stool and urine

Van den Bergh reaction ,[object Object],[object Object],[object Object]

Differences between unconjugated bilirubin and conjugated bilirubin

Heme catabolism is classified into several stages ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Stage II

Stage III : This is produced by the action of intestinal bacteria. ,[object Object]

Plasma Bilirubin or Bile Pigments ,[object Object],[object Object],[object Object],[object Object],[object Object]

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[object Object],[object Object], HYPERBILIRUBINEMIA

A-Unconjugated Hyperbilirubinemia ,[object Object]

Unconjugated hyperbilirubinemia occurs in the following conditions ,[object Object]

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II-Hemolytic jaundice (Anemia) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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B-Conjugated Hyperbilirubinemia ,[object Object],[object Object],[object Object],[object Object]

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Hyperbilirubinemia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bilirubin estimation

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Bilirubin estimation