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Chapter 3: The New Genetics Alma Villanueva, MA California State University, Los Angeles Overview Genetic Code The Beginning of Life Male & Female Twins Genotype & Phenotype Disorders Genetic Counseling Genetic Code Cells Basic unit of life Trillions! Nucleus Chromosomes Thread– like structures made up of DNA & protein 23 pairs DNA (Deoxyribonucleic acid) 2 strands twisted in a double helix Chemical composition of molecules that contain the genes Contains all of the information required to build/maintain the cell 3 Genes Small section of the chromosome 18,000 – 23,000 genes Each gene provides a unique recipe to make a protein 4 bases Code for your traits A - adenine T - thymine C - cytosine G – guanine Only 4 possible pairs A-T; T-A; C-G; G-C http://mybrainnotes.com/brain-dna-behavior.html 4 Allele A variation of a gene Example: the gene for eye color has several variations (alleles); an allele for blue eye color or an allele for brown eyes Everyone inherits alleles from sperm & ovum Genetic diversity Distinguishes each person Allows the human species to adapt to pressures of the environment Genome Full set of genes with instructions to make a living organism Genomes exist for each species Video about Genes 5 The Beginning of Life Two Parents, Millions of Gametes Gamete Reproductive cell Sperm or Ovum Each contains 23 pairs Zygote Cell formed with union of Sperm & Ovum Produce a new individual with 23 chromosomes from each parent Conception http://predictingbabygender.info/tag/intercourse-timing/ Matching genes Genotype Organism’s entire genetic inheritance, or genetic potential. Homozygous (same zygote) Two genes of one pair that are exactly the same in every letter of their code Heterozygous Two genes of one pair that differ in some way Usually not an issue Male of Female? Humans usually possess 46 chromosomes 44 autosomes and 2 sex chromosomes SEX chromosome = 23rd pair Female – XX Male – XY Mother’s contain X Father’s may have X or Y X chrom. Is larger & more genes Y contain SRY, making male hormones & organs It's a girl! Uncertain Sex “ambiguous genitals,” = child's sex is not abundantly clear a quick analysis of the chromosomes is needed, to make sure there are exactly 46 and to see whether the 23rd pair is XY or XX shown here a baby boy (left) and girl (right). Too Many Boys? Is sex selection the parents’ right or a social wrong? Preference for boys in many areas of world Ways to prevent female birth Inactivating X sperm before conception In vitro fertilization (IVF) Aborting XX fetuses My Strength, My Daughter slogan these girls in New Delhi are shouting at a demonstration against abortion of female fetuses in India The current sex ratio of children in India suggests that this campaign has not convinced every couple. New Cells Within hours of conception 23 pairs of chromosomes carrying all the genes duplicate, forming two complete sets of the genome Two sets.
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Human genome project[1]
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Human Genome Project
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