1. CHARACTERIZING DISEASE RESISTANCE IN NATIVE OYSTERS That Have Experienced Disease Pressure Roxanna Smolowitz, Steven Roberts, Jackie DeFaveri Christina Romano, Rick Karney
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4. Oysters that had experienced disease pressure Oysters that had not experienced disease pressure (naïve) Spawn Spawn Experimental Design
5. Oysters (~4000 from each group) were grown in a Dermo prone site- Edgartown Great Pond July 2005 - Present
11. Photo: Gary H. Wikfors: Northeast Fisheries Science Center, NOAA Fisheries Milford Laboratory, Milford, CT Immune Response in Oysters
12. What are the biochemical or gene products produced by hemocytes?
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14. CIAPIN Expression cytokine induced apoptosis inhibitor 1 Survivors of Dermo pressure [Edgartown GP] Naive [Tisbury] Apoptosis (programmed cell death) regulation is likely involved in disease resistance
15. Survivors of Dermo pressure [Edgartown GP] Naive [Tisbury] Cathepsin L Expression Cathepsins are a family of proteases Proteases and protease inhibitors have been shown to play critical roles in immunity and host-parasite interactions. One possibility is Cathepsin L is involved in P. marinus defense activity.