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CLINICAL ASPECTS OF  CEPHALOSPORIN AND PENEM GROUP OF  ANTIBIOTICS
Beta lactam Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cephalosporins ,[object Object],[object Object],[object Object],[object Object],[object Object]
Classification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SECOND GENERATION G+ve  G-ve  beta lactamase stability ++  ++  + + ORAL  PARENTERAL Cefamandole  C efaclor Cefotiam  Cefuroxime axetil  Ceforanide  Cefprozil Cefonicid  Cefuroxime Cefmetazole  Cefacetrile  Cefotiam  Cefranide  Loracarbef  Cefoxitin *  Cefotetan * *  Cephamycins
THIRD  GENERATION G+ve  G-ve  beta lactamase stability +/++  +++  ++ + ORAL  PARENTERAL Cefsulodin  Ceftiofur Ceforanide  Cefotaxime Cefpodoxime proxetil  Cefmenoxime Cefixime  Ceftriaxone Ceftibuten  Ceftizoxime  Cefdinir  Ceftazidime Cefmenoxime  Cefovecin Cefditren pivoxil  Cefoperazone Cefodizime  Latamoxef (moxalactam)* Cefetamet *  Cephamycins
FOURTH  GENERATION G+ve  G-ve  beta lactamase stability ++/+++  ++++  + ++ + ORAL  PARENTERAL Cefmetazole  Cefepime Cefditoren  Cefpirome Cefquinome
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],FIRST GENERATION
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
CARBAPENEMS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CARBAPENEMS…contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Imipenem…contd ,[object Object],[object Object],[object Object],[object Object]
Meropenem ,[object Object],[object Object],[object Object],[object Object]

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Cephalosporins penems

  • 1. CLINICAL ASPECTS OF CEPHALOSPORIN AND PENEM GROUP OF ANTIBIOTICS
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. SECOND GENERATION G+ve G-ve beta lactamase stability ++ ++ + + ORAL PARENTERAL Cefamandole C efaclor Cefotiam Cefuroxime axetil Ceforanide Cefprozil Cefonicid Cefuroxime Cefmetazole Cefacetrile Cefotiam Cefranide Loracarbef Cefoxitin * Cefotetan * * Cephamycins
  • 7. THIRD GENERATION G+ve G-ve beta lactamase stability +/++ +++ ++ + ORAL PARENTERAL Cefsulodin Ceftiofur Ceforanide Cefotaxime Cefpodoxime proxetil Cefmenoxime Cefixime Ceftriaxone Ceftibuten Ceftizoxime Cefdinir Ceftazidime Cefmenoxime Cefovecin Cefditren pivoxil Cefoperazone Cefodizime Latamoxef (moxalactam)* Cefetamet * Cephamycins
  • 8. FOURTH GENERATION G+ve G-ve beta lactamase stability ++/+++ ++++ + ++ + ORAL PARENTERAL Cefmetazole Cefepime Cefditoren Cefpirome Cefquinome
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
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  • 16.
  • 17.
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