Generic Norvasc (Amlopres Tablets) is used to lower high blood pressure (hypertension) and to treat angina pectoris.

1. Generic Norvasc Tablets
Generic Norvasc Tablets (Amlopres)
are used to lower high blood pressure
(hypertension) and to treat angina
pectoris.
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2. Generic Norvasc Tablets
Chemical Structure
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3. Generic Norvasc Tablets
Active Ingredient
The active ingredient in Generic
Norvasc (Amlopres Tablets) is
Amlodipine Besylate (Besilate), which
is a calcium channel blocker.
•Each 10mg tablet contains
amlodipine besylate equivalent to 10
mg amlodipine. Amlopres tablets are
also available in strengths of 2.5 mg
and 5 mg.
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4. Generic Norvasc Tablets
Indications
High Blood Pressure (Hypertension):
High blood pressure results from blood
pushing too hard against your blood
vessels. Generic Norvasc relaxes your
blood vessels, which lets your blood flow
more easily and helps lower your blood
pressure. Medicines that lower blood
pressure lower your risk of having a stroke
or heart attack.
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5. Generic Norvasc Tablets
Indications
Angina Pectoris:
Angina, or Angina Pectoris is a pain or
discomfort that keeps coming back when
part of your heart does not get enough blood
and thus a lack of oxygen supply and waste
removal. Angina feels like a pressing or
squeezing pain, usually in your chest under
the breastbone. Sometimes you can feel it in
your shoulders, arms, neck, jaws, or back.
Generic Norvasc can relieve this pain.
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6. Generic Norvasc Tablets
Recommended Adult Dosage
For both hypertension and
angina, the recommended initial
dose is 5 mg Generic Norvasc
once daily which may be
increased to a maximum dose of
10 mg depending on the
individual patient's response.
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7. Generic Norvasc Tablets
Recommended Adult Dosage
Small, fragile, or elderly patients, or
patients with hepatic insufficiency
may be started on 2.5 mg once daily.
Swallow the tablet whole with a full
glass of water. Take your medicine at
about the same time each day, either
morning or evening.
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8. Generic Norvasc Tablets
Missed Dose
If you miss a dose, take it as soon as
you remember.
However, if you remember when it is
less than 12 hours for your next dose,
take only your usual dose at your
regular time.
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9. Generic Norvasc Tablets
Contraindications
Generic Norvasc (Amlopres Tablets) are
contraindicated in the following cases:
➔Known hypersensitivity to amlodipine,
dihydropyridines or any inactive ingredients
of this medication.
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10. Generic Norvasc Tablets
Side Effects of Generic Norvasc
Generic Norvasc may cause the following side
effects: Headache, swelling of your legs or
ankles, tiredness, extreme sleepiness, stomach
pain, nausea, dizziness, flushing (hot or warm
feeling in your face), arrhythmia (irregular
heartbeat), heart palpitations (very fast
heartbeat).
It is rare, but when you first start taking Amlopres
(Generic Norvasc) or increase your dose, you
may have a heart attack or your angina may get
worse. If that happens, call your doctor
immediately or go directly to a hospital
emergency room
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11. Generic Norvasc Tablets
Warnings And Precautions
➔Symptomatic hypotension is possible, particularly in
patients with severe aortic stenosis. However,
because of the gradual onset of action, acute
hypotension is unlikely.
➔Worsening angina and acute myocardial infarction
can develop after starting or increasing the dose of
Generic Norvasc, particularly in patients with severe
obstructive coronary artery disease.
➔The dosage of Generic Norvasc has to be titrated
slowly when administering calcium channel blockers
to patients with severe hepatic impairment.
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12. Generic Norvasc Tablets
Overdosage Symptoms
Overdosage might be expected to cause
excessive peripheral vasodilatation with
marked hypotension and possibly a reflex
tachycardia. Dysrhythmias may occur
following overdose with any calcium
antagonists. Hypotension and bradycardia
are usually seen within 1 to 5 hours
following overdose. Hypotension can
persist for longer than 24 hours despite
treatment. Cardiac rhythm disturbances
have been noted to persist for up to 7 days.
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13. Generic Norvasc Tablets
Overdose Treatment
Active cardiac and respiratory monitoring should
be instituted. Frequent blood pressure
measurements are essential. Should hypotension
occur, cardiovascular support including elevation
of the extremities and the judicious administration
of fluids should be initiated.
If hypotension remains unresponsive to these
conservative measures, administration of
vasopressors (such as phenylephrine), should be
considered with attention to circulating volume
and urine output.
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14. Generic Norvasc Tablets
Overdose Treatment
Administration of activated charcoal
immediately or up to two hours after
ingestion of Generic Norvasc has been
shown to significantly decrease amlodipine
absorption.
Intravenous calcium gluconate may be
beneficial in reversing the effects of calcium
channel blockade. Dialysis is not likely to
be of benefit since amlodipine is highly
protein-bound.
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15. Generic Norvasc Tablets
Amlopres Tablets Manufactured
by Cipla Ltd., India
For more information click here
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