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Cardiodrugs

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Tosca Torres
Tosca Torres
Salud y medicina
1 de 136
Cardiovascular Drugs Ma. Tosca Cybil A. Torres, RN, MAN
Learning Objectives ,[object Object],[object Object],[object Object],[object Object]
Antihypertensive
Hypertension ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Goal with hypertension: ,[object Object],[object Object],[object Object],[object Object]
o
Pharmacotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Diuretics ,[object Object],[object Object],[object Object]
Loop Diuretics ,[object Object],[object Object],[object Object]
Loop Diuretics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Loop Diuretics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thiazide ,[object Object],[object Object]
Thiazide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thiazide ,[object Object],[object Object],[object Object]
NCs: Thiazide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Potassium Sparing Diuretics ,[object Object],[object Object],[object Object],[object Object],[object Object]
Potassium Sparing Diuretics cont ,[object Object],[object Object],[object Object],[object Object],[object Object]
NCs: Potassium Sparing Diuretics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Calcium Channel Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object]
Calcium Channel Blockers cont. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Calcium Channel Blockers cont. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Calcium Channel Blockers cont. ,[object Object],[object Object],[object Object],[object Object],[object Object]
NCs: Calcium Channel Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
e
RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (RAAS) Angiotensinogen in plasma Juxtaglomerular cells-kidney ↓ Serum Sodium ↓Blood volume Angiotensin I Kidney tubules Angiotensin II Adrenal Cortex ↑ Sodium resorption (H2O resorbed with sodium); ↑ Blood volume RENIN Angiotensin-converting enzyme ALDOSTERONE Intestine, sweat glands, Salivary glands Via vasoconstriction of arterial smooth muscle
Angiotensin Converting Enzyme Inhibitors (ACE-I)- “prils” ,[object Object],[object Object],[object Object]
Angiotensin Converting Enzyme Inhibitors (ACE-I)- “prils” cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
te
NCs: ACE Inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Angiotensin II Receptor Blockers (ARB’s)- “sartans” ,[object Object],[object Object],[object Object],[object Object],[object Object]
Angiotensin II Receptor Blockers (ARB’s)- “sartans” cont. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Angiotensin II Receptor Blockers (ARB’s)- “sartans” cont ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Beta Blockers- “olols ,[object Object],[object Object],[object Object],[object Object],[object Object]
Beta Blockers- “olols cont. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Beta Blockers- “olols cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Beta Blockers- “olols cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NCs: Beta-adrenergic Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
y
Alpha 1 -adrenergic Antagonists ,[object Object],[object Object]
NCs: Alpha 1 -adrenergic Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Direct Vasodilators ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NCs: Direct Vasodilators ,[object Object],[object Object],[object Object],[object Object],[object Object]
Direct Vasodilators ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
Cardiac Glycosides ,[object Object],[object Object]
Action Potential
Cardiac Glycosides ,[object Object],[object Object],[object Object],[object Object]
Inotropes
Inotropes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class Participation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class Participation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiac Glycosides ,[object Object]
Digoxin MOA
Digoxin (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chronotropes
Chronotropes ,[object Object],[object Object],[object Object]
Chronotropes (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Positive Chronotrope ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Atropine (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Nursing Responsibilities ,[object Object],[object Object],[object Object],[object Object]
Anti-anginal Drugs
Antianginal Drugs ,[object Object],[object Object],[object Object]
Angina Pectoris ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Symptoms of Angina
Nitrites/Nitrates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class Participation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class Participation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Drug (Trade Name) Common Dosage Onset Duration Amyl nitrate (Vaporole ® ) 0.3 ml inhalation 30-60 sec 10 min ISDN (Isordil ® ) 2.5 - 10 mg SL 5 - 30 mg po qid 2-5 min 2 - 4 hr Nitroglycerin ( Nitro-bid ® ) 2% ointment 15 min 4 - 8 hr ( Nitrostat ® ) 0.3 - 0.6 mg SL 1-3 min 10 - 45 min ( Nitrogard ® ) 1,2,3 mg XR tab 30 min 8 - 12 hr ( Transderm-Nitro ® ) 2.5 - 15 mg/day Transdermal patch 30-60 min 24 hr
MOA ,[object Object],[object Object],[object Object]
Nitroglycerin (NG) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NG (cont’d) ,[object Object],[object Object],[object Object],[object Object]
NG (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antidysrhythmics Antiarrhythmics
What are Arrhythmias? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antidysrhythmics/Antiarrhythmics ,[object Object],[object Object],[object Object]
Antidysrhythmics/Antiarrhythmics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiac Action Potential ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antiarrthymics: Class I ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class I A ,[object Object],[object Object],[object Object]
Class 1A – Quinidine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class 1A – Quinidine (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class I B ,[object Object],[object Object],[object Object],[object Object]
Lidocaine – Class IB ,[object Object],[object Object]
Lidocaine – Class IB (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class I C ,[object Object],[object Object]
Flecainide – Class IC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Flecainide – Class IC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class II – Beta Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Propranolol Warning ,[object Object],[object Object],[object Object],[object Object]
Class III ,[object Object],[object Object],[object Object],[object Object],[object Object]
Amiodarone – Class III ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Amiodarone – Class III (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class IV ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sympathomimetics
Sympathomimetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Epinephrine ,[object Object],[object Object],[object Object],[object Object],[object Object]
Epinephrine MOA
Epinephrine (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Epinephrine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vasopressors
Vasopressors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vasoconstrictor ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vasopressin ,[object Object],[object Object],[object Object],[object Object]
Vasopressin (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vasopressin (cont’d) ,[object Object],[object Object],[object Object],[object Object]
Vasopressin (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anticoagulants
Antiplatelets/Anticoagulants ,[object Object],[object Object],[object Object]
Types of Antiplatelets/Anticoagulants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antiplatelets/Anticoagulants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Coagulation Cascade
Warfarin – Oral Anticoagulant ,[object Object]
Warfarin (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Warfarin Warnings ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Warfarin (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
Fibrinolytic Enzymes
Fibrinolytic Enzymes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Streptokinase (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Streptokinase (cont’d) ,[object Object],[object Object],[object Object],[object Object]
Streptokinase (cont’d)
Antilipidemics
Antilipidemics ,[object Object]
Types of antilipidemics ,[object Object],[object Object],[object Object],[object Object]
Side effects ,[object Object],[object Object],[object Object],[object Object]
Nursing responsibilities ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]

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Pediatric Neurologic Disorders
 
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Neurologic disordersNeurologic disorders
Neurologic disorders
 
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Liver cirrhosis
Liver cirrhosisLiver cirrhosis
Liver cirrhosis
 
Neurologic Exam
Neurologic ExamNeurologic Exam
Neurologic Exam
 
Diabetes Mellitus
Diabetes MellitusDiabetes Mellitus
Diabetes Mellitus
 
Nervous System-Review
Nervous System-ReviewNervous System-Review
Nervous System-Review
 
Urinary Catheterization
Urinary CatheterizationUrinary Catheterization
Urinary Catheterization
 
Urinary Elimination
Urinary EliminationUrinary Elimination
Urinary Elimination
 
Perception And Coordination Revised
Perception And Coordination RevisedPerception And Coordination Revised
Perception And Coordination Revised
 
oxygenation
oxygenationoxygenation
oxygenation
 
Metabolism
MetabolismMetabolism
Metabolism
 
Elimination
EliminationElimination
Elimination
 
A Patient’S Bill Of Rights
A Patient’S Bill Of RightsA Patient’S Bill Of Rights
A Patient’S Bill Of Rights
 
Autonomic Nervous System Agents
Autonomic Nervous System AgentsAutonomic Nervous System Agents
Autonomic Nervous System Agents
 
Reproductive System Drugs
Reproductive System DrugsReproductive System Drugs
Reproductive System Drugs
 

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