2. Introduction
⢠Also known as Contraception
⢠Limiting of family size or prevention of
unwanted and unintended pregnancy
⢠There are about 1.2 billion women of
reproductive age world wide
⢠About 114 million acts of sexual intercourse
per day worldwide
⢠IMAGINE WHAT WILL HAPPEN without
CONTRACEPTION?!
3. Nigeria burden
⢠High total fertility rate (TFR) of 5.7 (NDHS
2008).
⢠High population
⢠High annual population growth rate of 3.2%.
⢠At this growth rate the Nigerian population
should double in only 22 years!
⢠Unfortunately, Low Contraceptive prevalence
14.6% for any method and 9.7% for modern
methods(NDHS,2008)
4. Classes of contraceptive users
⢠Single ladies including adolescents, unstable
relationships,coital exposure unpredictable
⢠Married women or ladies in stable
relationships desirous of child spacing services
⢠Couples with completed family sizes
5. Family planning methods:
Classification
A. Coitus Interruptus or Withdrawal
Method
B. Natural FP Methods (Safe Period and
Abstinence)
â
â
â
â
â
â Inert forms
â Copper bearing
â Hormone bearing
Cervical mucus (Spinberkeit)
Temperature
Sympto-thermal
Cycle beads (Standard Days Method)
Ovulation prediction devices
E. Barrier methods
OCP (COC, POCP)
Hormone bearing / containing IUDs
Nasal spray
Injectables
Implants
Contraceptive Skin patches
Vaginal rings
F. Permanent methods
C. Hormonal methods
â
â
â
â
â
â
â
D. Intrauterine devices
â
â
â
â
â
â
â
â
â
Male condom
Female condom
spermicides
Cervical caps
Diaphragm
Vasectomy
BTL
Quinacrine
Essure
G. Emergency Contraception
6. A: Abstinence and Withdrawal (Coitus
Interruptus) Methods
⢠Abstinence (many wives a modification?)
⢠Withdrawal?
7. B: Natural Family Planning (NFP)
Methods:
⢠Fertility Awareness Based Methods (FAM),
⢠Lactational Amenorrhoea Method (LAM)
⢠Standard Days Method (SDM)
⢠Ovulation Prediction Tests (OPT)
8. Natural Family Planning (NFP) & Fertility
Awareness-Based Methods (FAM)
⢠Use of physical signs, symptoms, and cycle
data to determine when ovulation occurs
⢠Spouses abstain from intercourse during the
at-risk fertile days
⢠Or use other methods to avoid pregnancy
â Condom, Emergency Contraception
9. Effectiveness of NFP (FAM, LAM, SDM, OPT)
⢠The success of the Natural Family Planning
methods depends on:
â the accuracy of the method in identifying the
womanâs actual fertile days
â Couplesâ ability to correctly identify the fertile
time
â Coupleâs ability to follow the rules of the method
they are using
10. Methods of Determining High-Risk Fertile Days
⢠The basal body temperature (BBT) method
⢠The calendar/rhythm method
⢠The cervical mucus method (CMM) or Billings
ovulation method.
⢠The sympto-thermal method (STM)
⢠Cycle beads
⢠Ovulation prediction tests
11. Cycle Beads
⢠Also called a Standard Days Method
⢠Identifies fertile and infertile days of the cycle
⢠Cycle beads has 32 beads, each bead
represents a day of the menstrual cycle
⢠The red bead represents first day of
menstruation and of the cycle
⢠White beads represent days when a woman
can get pregnant
⢠95% effective with perfect use!
12.
13. Breastfeeding, Lactation Amenorrhea
Method (LAM)
⢠Breastfeeding delays return of fertility
postpartum
⢠However, LAM is a contraceptive method
based on exclusive breastfeeding
⢠LAM is an effective method only under
specific conditions:
â Woman breastfeeding exclusively
â The woman is amenorrhoeic
â The infant less than 6 months old
14. C. Hormonal Contraception
Mechanism of action:
â˘Suppress ovulation (90 to 95% of time)
â˘Causes thickening of cervical mucus, which
impedes sperm penetration and entry into the
upper reproductive tract
â˘Causes endometrial atrophy
â˘May slow down tubal motility
16. COCP
⢠Dose of oestrogen in the COCPs
ranges from 15 to 50 Îźg.
Trend towards lower dosages with most being
low dose containing 30-35 Îźg
⢠Lower doses (15 Οg ethinylestradiol)
associated with similar efficacy as 30 Îźg pills,
less cardiovascular risks and poorer cycle
control with higher incidence of breakthrough
bleeding
18. Types: Combined Injectable Contraceptives
given Monthly
⢠MPA combined with estradiol cypionate (E2C)
â Cyclofem, Lunelle (25mg MPA and 5 mg E2C)
⢠Net-En combined with estradiol valerate (E2V)
â Mesigyna, Norigynon 50mg Net-En; 5mg E2V
19. 3. Contraceptive Implants
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â˘
â˘
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Six Rods, Norplant (levonorgestrel) â 5 years
Two rod Norplant 11 (levonorgestrel)â 3 years
Two rod Jadelle (levonorgestrel) â 5 years
One rod Implanon (etonogestrel) â 3 years
Bio-degradable (Capronor) â 2 years
does not require removal
23. 4: Intra-Uterine Devices Bearing or
Containing Hormones
⢠Hormone bearing IUDs have lower pregnancy
rates and fewer side effects
⢠Hormone containing IUDs may actually also
reduce risk of PID
⢠The levonorgestrel IUD has a preventive effect
against the occurrence of ectopic pregnancy
24. Intrauterine System
⢠The IUS (Intrauterine System) releases
levonorgestrel (a progestin),
â Levo-Nova (registered in Finland)
â Mirena (registered in the UK and Canada)
⢠Other Uses:
â Treatment of Menorrhagia
â In HRT
⢠Introduced in 1990
25. Progestasert
⢠Contained progesterone that was released at
a rate of 65 micrograms per day.
⢠Was replaced annually, though approved for
18 months of use in France.
⢠Failure rate: 2% per year
⢠Introduced in 1976 and discontinued in 2001
27. Combined contraceptive vaginal
ccring
⢠Releases 15ΟgEE and 120Οg etonorgestrel/day
(Nuvaring,
Organon)
⢠Ring consists of soft ethylene-vinyl-acetate
(EVA) copolymer
⢠last for 3 weeks
⢠Efficacy similar to COCPs but incidence of
irregular bleeding only about one-eight of
that reported for COCPs
28. How the Ring is Used
⢠A new vaginal ring needs to be inserted every
month.
⢠Once inserted, the Ring is worn for 3
consecutive weeks before it is removed for 1
week.
⢠During the week that the Ring is not worn,
menstruation occurs.
⢠Each ring provides a monthâs contraception
30. The Contraceptive Patch
⢠Trans-dermal contraceptive system
⢠Square, flexible, extended-release matrix
patch system
⢠Contains norelgestromin (NGMN) and ethinyl
estradiol (EE) for use in a weekly dosing
schedule
⢠Product launched: April 2002
31. Benefits of the Patch
â˘
â˘
â˘
â˘
â˘
Female-controlled
Prompt contraceptive reversibility
Allows for spontaneity
Highly efficacious contraceptive
High rates of compliance across age groups
32. Method of use
⢠A woman applies her first patch onto her
â upper outer arm,
â buttocks,
abdomen
thigh
⢠Applied weekly
⢠The day of application is known from that point as patch
change day.
33. Method of use
⢠On the 4th patch change day, the patch is
removed and not replaced.
⢠The woman waits 7 days without a patch in
place, and on the next patch change day she
applies a new patch (a new cycle)
34. D: Intrauterine Devices
Types:
â˘Chemically inert devices- composed of a
nonabsorbable material, most often
polyethylene, and impregnated with barium
sulfate for radiopacity.
⢠Chemically active devices have continuous
elution of copper or a progestational agent.
Only chemically active IUDs are available
currently in most parts of the world.
35. âŚ.IntrauterineDevices
Intrauterine device
⢠Most available ones have a plastic frame with
copper wire wound round the stem or copper
sleeves on the end of the arms.
⢠Amount of copper : 250-375mm2.
⢠One IUD is frameless (GyneFix) and consists
of six copper beads on a nylon thread.
36. Intrauterine Devices
⢠Devices containing 250 mm2 are licensed for 3
years, the T-Safe Cu 380A for 8 years and the
remainder for 5 years.
⢠IUDs containing 380mm2
Copper have failure rate of 1 per 100 women
in the first year of use.
37. Contraindications
⢠Current RTI or PID
⢠History of malignant trophoblastic disease or
Endometrial cancer
⢠Pelvic Tuberculosis
38. Side effects
⢠There may be heavier and prolonged bleeding
during the first 3 to 6 months of use.
⢠Dysmenorrhoea
⢠Uterine perforation
⢠Expulsion
⢠Ectopic pregnancy
39. As regards risks of ectopic preg
⢠Contraceptive effect decreases the absolute
number of ectopic pregnancies by half,
compared with women not using
contraception
⢠When contraceptive failure occurs, pregnancy
is still more likely to be ectopic
40. Mechanism of Action of IUDs
⢠Inflammatory reaction in the endometrium
leading to phagocytosis of sperms
⢠Copper ions are also spermicidal, inhibiting
sperm motility and inhibiting acrosomal enzyme
activation so that sperms rarely reach the tubes
⢠Progestogen impregnated IUDs cause thickening
of the cervical mucus: changes the uterotubal
fluid that hinders sperm migration; and some
anovulatory effects (5-15%) of treatment cycles.
41. Hormone Containing IUDs
⢠Progestasert: Contains pure Progesterone
â Meant for 1 year
â Not easily available
⢠Levonova: levonorgestrel IUD (Mirena)
â May actually reduce menstrual loss
â Lasts for 5 and up to 7 years
NB: Hormone containing IUDs may actually also reduce risk of
PID
â The levonorgestrel IUD has a preventive effect against the
occurrence of ectopic pregnancy
42. E: Barrier Methods of Contraception
â Male condom
â Female condom
â Diaphragm
â Cervical Cap
â Spermicides
â˘
â˘
â˘
â˘
Aerosols
Sponges
Tablets
Gels , etc.
43. Male Condoms
⢠Made from latex rubber. Less commonly,
polyurethane or the cecum of lambs
⢠Provide effective contraception
⢠Provides protection against RTIs
⢠Failure rate as low as 3 or 4 per 100 coupleyears of exposure
44. Condition max. effectiveness
⢠Use with every coital act.
⢠Placed before contact of the penis with the
vagina.
⢠Withdrawal with the penis still erect
⢠Holding the base of the during withdrawal
⢠Use of an intravaginal spermicide or a condom
lubricated with spermicide
45. Non allergic condoms
⢠Made of synthetic thermoplastic elastomer
such as polyurethane
⢠Effective against sexually transmitted diseases
⢠Have an significantly higher breakage and
slippage rate than latex condoms
46. Female condoms
⢠Prevent pregnancy and sexually transmitted
diseases
⢠Made of polyurethrane
⢠Has higher slippage rate than male
polyurethrane condom
⢠Pregnancy rate higher than with the male
condom
47. F. Permanent methods of
Contraception
Considered irreversible
Considered irreversible
⢠Male
⢠Female
â Easier
â Cheaper
â Complications less
â More costly
â More technical
â More complications
48. Male Permanent Methods
Vasectomy:
â˘Through a small incision in the
scrotum, the lumen of the vas deferens is
disrupted to block the passage of sperm from
the testes
â˘Cheaper, less complications, lower failure rate
â˘Sterility is not immediate.
49. Vasectomy
⢠Complete expulsion of sperm takes about 3
months or 20 ejaculations
⢠Recommend that semen should be analyzed
until two consecutive sperm counts are zero.
⢠failure rate for vasectomy is much less than 1
percent
53. G. Emergency contraception
⢠Yuzpe Regimen
â High Dose Combined Pills
â Low Dose Combined Pills
⢠Progestin Only (High Dose)
â Postinor
â Provera
⢠IUD: Inserted within 5 days of Coitus
⢠Mifepristone (RU 486)
54. ⢠The Yuzpe regimen, a combination of
100 Îźg ethinyloestradiol and 0.5mg LNG taken
twice with the two doses separated by 12 h
⢠Progestin only : LNG 1.5 mg ,single dose
within 72 h of intercourse
0.75 mg levonorgestrel taken twice 12 h apart
starting within 72 h of intercourse.
55. Mechanism of Action of OCPs in Emergency
Contraception
⢠If taken before ovulation, ECPs disrupt
normal follicular development and
maturation,
⢠Block LH surge, and inhibit ovulation,
⢠May also create deficient luteal phase,
⢠May affect tubal transport of sperm or
ova
56. Mechanism of Action of IUD in Emergency
Contraception
⢠IUD in EC
â Causes endometrial changes that inhibit ovulation
â Copper ions released appear to be directly
embryotoxic
â Rarely, may act as contraceptive, if inserted days
before ovulation
57. Emergency Contraception with Mifepristone
(RU-486)
An anti-progestogen: Single dose of 10mg to
25mg (China) mifepristone (RU-486), taken
within 5 days of unprotected intercourse.
Effectiveness: Prevent over 98% of pregnancies
Mechanism of Action
⢠Blocks action of progesterone by binding to its
receptors
⢠Stops ovulation if given in follicular phase
(contraceptive)
⢠Slows endometrial maturation in luteal phase
(interceptive)