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Chapter 4

Structure and Function of Cells
Cells are the basic units of life
All organisms are composed of cells
• Cell theory states
  – A cell is the basic unit of life
  – All living things are made up of cells
  – New cells arise only from preexisting cells
Metabolically active cells are small in size

Why are cells so small?
 Cells need a surface area large enough to gain
 nutrients and get rid of waste.
Prokaryotic cells evolved first
• Prokaryotic (“before” “nucleus”) cells lack a membrane
  bound nucleus
• Prokaryotic cells are also much smaller than eukaryotic
• Domains Bacteria and Archaea are prokaryotic
• All cells contain
   – Cell membrane (plasma membrane)
   – Cytoplasm
   – Genetic material
• Prokaryotic cells contain
     – Cell membrane
         • Allows substances in and
           out
     – Cytoplasm
         • Fluid that fills cell
     – Ribosomes
         • Protein synthesis
     – Cell wall
         • Holds cell shape
     – Pili
         • Allows attachment to solid
           surfaces
     – Flagella (some cells)
         • movement


Prokaryotic cells cause disease, decompose dead material, and are used in the
production of food and drugs.
Eukaryotic cells contain specialized
            organelles
• Eukaryotic (“true” “nucleus”) cells have a membrane
  bound nucleus
• Domain Eukarya contains eukaryotic cells
• Larger than prokaryotic cells
• Less surface area to volume
• Contains organelles (“little organs”) that perform specific
  functions
Animal Cell




Plant Cell – Notice the cell
wall, chloroplasts, and large
central vacuole
Protein synthesis is a major
             function of cells
The nucleus contains the cell’s genetic information
• Chromosomes
   – DNA and proteins
• Chromatin
   – Extended chromosomes after cell division
• Nucleolus
   – Region of chromatin where subunits of ribosomes are produced
• Nuclear envelope
   – Separates nucleus from cytoplasm
• Nuclear pores
   – Allows ribosomal subunits out and proteins in
The ribosomes carry out protein
            synthesis
• Do not have membranes
• Polyribosomes
   – Group of ribosomes
• Endoplasmic reticulum
   – Rough version has ribosomes attached to it
• Messenger RNA
   –   Copy of a gene
   –   Tells cell how to make a particular protein
   –   Indicates correct sequence of amino acids
   –   Leaves nucleus via nuclear pore
   –   Attaches to ribosome
   –   Protein is produced
The endoplasmic reticulum synthesizes
  and transports proteins and lipids
• Many ribosomes attach to the endoplasmic
  reticulum, making it a site of protein production
• Types of ER
   – Rough ER
      • Has ribosomes attached
      • Make proteins
   – Smooth ER
      • Does not have ribosomes attached
      • Make lipids
• Transport vesicles
   – Pinched off portions of ER that contain proteins,
     membranes, and lipids going mainly to the Golgi
     apparatus
The Golgi apparatus modified and
      repackages proteins for distribution
• Receives, processes, and packages proteins and lipids,
  so that they may be sent to their final destination
• Receives at inner face
• Processes as it moves from inner face to outer face
• Packages into vesicles that leave from the outer face
   – Some are secretory vesicles that discharge contents out of the
     cell. Also called exocytosis.
Vacuoles and vesicles have varied
           functions
Lysosomes digest biomolecules and cell
  parts
• Vesicles produced by Golgi apparatus
• Have low internal pH that digests old and
  worn-out organelles
• White blood cells engulf bacteria and
  digest it to protect your body
Peroxisomes break down long-
          chain fatty acids
• Help produce cholesterol and important
  phospholipids
• In germinating seeds, convert fatty acids
  and lipids to sugars that are used as
  energy
Vacuoles are common to plant cells
• Store water, sugars, salts, toxins (protects
  plant from herbivory), and water-soluble
  pigments (responsible for flower color)
• Central vacuole provides support to the
  plant
• Stores waste and breaks down old
  organelles like lysosomes in animal cells
Vesicles allow the organelles of the
        endomembrane system to work together
1. Proteins, produced in the rough
   ER are carried in
2. Transport vesicles to
3. The Golgi apparatus, which sorts
   the proteins and packages them
   into vesicles that transport them to
   various cellular destinations
4. Secretory vesicles take proteins to
   the plasma membrane, where they
   exit the cell when the vesicles fuse
   with the membrane
5. In animal cells, lysosomes
   produced by the Golgi apparatus
6. Fuse with incoming vesicles from
   the plasma membrane and digest
   biomolecules and debris
A cell carries out energy
            transformations
Chloroplasts and mitochondria have opposite
  functions
• Chloroplasts are found in plant cells and contain
  the green pigment chlorophyll, which is
  responsible for the ability to absorb solar energy
• Protists and algae also contain chloroplasts
• Mitochondria carry out cellular respiration
• Mitochondria produce ATP
(Cellular respiration and photosynthesis reactions)
The cytoskeleton is dynamic
The cytoskeleton maintains cell shape and assists movement
• Cytoskeleton
   –   Network of protein fibers within cytoplasm
   –   Holds organelles in place but allows them to move if needed
   –   Allows cells to change shape
   –   Support and movement
• Types of fibers
   – Actin filaments
        • Support plasma membrane
        • Largest
   – Intermediate filaments
        • Support nuclear envelope, plasma membrane, and cell to cell connections
        • Medium
   – Microtubules
        • Maintain shape of cell and act as tracks along which organelles can move
        • Smallest
Cilia and flagella permit movement
• Cilia
  – Short
  – Move an egg along the oviduct
  – Move mucus that contains debris out of lungs
• Flagella
  – Long tail
  – Sperm tail
Bio 100 Chapter 4
Bio 100 Chapter 4
Bio 100 Chapter 4

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Bio 100 Chapter 4

  • 1. Chapter 4 Structure and Function of Cells
  • 2. Cells are the basic units of life All organisms are composed of cells • Cell theory states – A cell is the basic unit of life – All living things are made up of cells – New cells arise only from preexisting cells
  • 3.
  • 4. Metabolically active cells are small in size Why are cells so small? Cells need a surface area large enough to gain nutrients and get rid of waste.
  • 5. Prokaryotic cells evolved first • Prokaryotic (“before” “nucleus”) cells lack a membrane bound nucleus • Prokaryotic cells are also much smaller than eukaryotic • Domains Bacteria and Archaea are prokaryotic • All cells contain – Cell membrane (plasma membrane) – Cytoplasm – Genetic material
  • 6. • Prokaryotic cells contain – Cell membrane • Allows substances in and out – Cytoplasm • Fluid that fills cell – Ribosomes • Protein synthesis – Cell wall • Holds cell shape – Pili • Allows attachment to solid surfaces – Flagella (some cells) • movement Prokaryotic cells cause disease, decompose dead material, and are used in the production of food and drugs.
  • 7. Eukaryotic cells contain specialized organelles • Eukaryotic (“true” “nucleus”) cells have a membrane bound nucleus • Domain Eukarya contains eukaryotic cells • Larger than prokaryotic cells • Less surface area to volume • Contains organelles (“little organs”) that perform specific functions
  • 8. Animal Cell Plant Cell – Notice the cell wall, chloroplasts, and large central vacuole
  • 9. Protein synthesis is a major function of cells The nucleus contains the cell’s genetic information • Chromosomes – DNA and proteins • Chromatin – Extended chromosomes after cell division • Nucleolus – Region of chromatin where subunits of ribosomes are produced • Nuclear envelope – Separates nucleus from cytoplasm • Nuclear pores – Allows ribosomal subunits out and proteins in
  • 10. The ribosomes carry out protein synthesis • Do not have membranes • Polyribosomes – Group of ribosomes • Endoplasmic reticulum – Rough version has ribosomes attached to it • Messenger RNA – Copy of a gene – Tells cell how to make a particular protein – Indicates correct sequence of amino acids – Leaves nucleus via nuclear pore – Attaches to ribosome – Protein is produced
  • 11. The endoplasmic reticulum synthesizes and transports proteins and lipids • Many ribosomes attach to the endoplasmic reticulum, making it a site of protein production • Types of ER – Rough ER • Has ribosomes attached • Make proteins – Smooth ER • Does not have ribosomes attached • Make lipids • Transport vesicles – Pinched off portions of ER that contain proteins, membranes, and lipids going mainly to the Golgi apparatus
  • 12. The Golgi apparatus modified and repackages proteins for distribution • Receives, processes, and packages proteins and lipids, so that they may be sent to their final destination • Receives at inner face • Processes as it moves from inner face to outer face • Packages into vesicles that leave from the outer face – Some are secretory vesicles that discharge contents out of the cell. Also called exocytosis.
  • 13. Vacuoles and vesicles have varied functions Lysosomes digest biomolecules and cell parts • Vesicles produced by Golgi apparatus • Have low internal pH that digests old and worn-out organelles • White blood cells engulf bacteria and digest it to protect your body
  • 14. Peroxisomes break down long- chain fatty acids • Help produce cholesterol and important phospholipids • In germinating seeds, convert fatty acids and lipids to sugars that are used as energy
  • 15. Vacuoles are common to plant cells • Store water, sugars, salts, toxins (protects plant from herbivory), and water-soluble pigments (responsible for flower color) • Central vacuole provides support to the plant • Stores waste and breaks down old organelles like lysosomes in animal cells
  • 16. Vesicles allow the organelles of the endomembrane system to work together 1. Proteins, produced in the rough ER are carried in 2. Transport vesicles to 3. The Golgi apparatus, which sorts the proteins and packages them into vesicles that transport them to various cellular destinations 4. Secretory vesicles take proteins to the plasma membrane, where they exit the cell when the vesicles fuse with the membrane 5. In animal cells, lysosomes produced by the Golgi apparatus 6. Fuse with incoming vesicles from the plasma membrane and digest biomolecules and debris
  • 17. A cell carries out energy transformations Chloroplasts and mitochondria have opposite functions • Chloroplasts are found in plant cells and contain the green pigment chlorophyll, which is responsible for the ability to absorb solar energy • Protists and algae also contain chloroplasts • Mitochondria carry out cellular respiration • Mitochondria produce ATP (Cellular respiration and photosynthesis reactions)
  • 18. The cytoskeleton is dynamic The cytoskeleton maintains cell shape and assists movement • Cytoskeleton – Network of protein fibers within cytoplasm – Holds organelles in place but allows them to move if needed – Allows cells to change shape – Support and movement • Types of fibers – Actin filaments • Support plasma membrane • Largest – Intermediate filaments • Support nuclear envelope, plasma membrane, and cell to cell connections • Medium – Microtubules • Maintain shape of cell and act as tracks along which organelles can move • Smallest
  • 19. Cilia and flagella permit movement • Cilia – Short – Move an egg along the oviduct – Move mucus that contains debris out of lungs • Flagella – Long tail – Sperm tail