SlideShare a Scribd company logo
1 of 15
H1N1                                                                       HIV




     MRSA                                                                       Bacillus anthracis




http://www.hsph.harvard.edu/academics/public-health-practice/; http://commons.wikimedia.org/wiki/File:HIV-1_Transmission_electron_micrograph_AIDS02bbb_lores.jpg; http://registrarism.files.wordpress.com/2009/07/swine-
flu.jpg; http://www.mrsablog.com/uploads/image/MRSa.jpg; http://uk.reuters.com/article/idUKTRE6203MF20100301; http://www.stoptherobbery.com/HealthGuide.html;
http://en.wikipedia.org/wiki/Penicillin; http://aps.unmc.edu/AP/main.php;
http://biosingularity.wordpress.com/2008/08/31/antibody-engineering-cuts-the-collateral-damage-of-cancer-drugs/
vs.




Mammen et al., 1998
http://www.nwfsc.noaa.gov/hab/habs_toxins/marine_biotoxins/detection/elisa.html; http://www.antibodyresearch.com/; http://bookbuilder.cast.org/view_print.php?book=28086
Polyvalent Therapeutics
Linker
Core




 Peptides
http://news.bbc.co.uk/2/hi/health/8021958.stm; http://www.youtube.com/watch?v=KMT1FLzEn9I
http://travel.nationalgeographic.com/places/gallery/china_great-wall-jinshanling.html
β-Defensin                                                                                Magainin-2                                                       Protegrin-1




                                                                Penicillin                                                                                                 Methicillin

Wang et al., Nucleic Acids Research 32, Database Issue D590-D592, 2004; Ganze et al. Nature Reviews Immunology 3, 710-720, 2003; Yang et al. Biochemistry, 42, 4669, 2003; wikipedia
Bacterial Cell



                                                                                                                          Pi




                                                                                                                        Cell Lysis




Nature Reviews Microbiology 3 238-250 (March 2005); www.istockphoto.com; http://cbsuapps.tc.cornell.edu/index.aspx
Fischbach et al.,                   S. aureus           S. simulans   Lysostaphin
                Science, 2009




                                                       Peptidoglycan
                                                       layer
                                       Cytoplasm
                                                       Cytoplasmic
                                                       membrane




www.toons4biz.com; www.clipartof.com
Pi

                    Pi




Effective Coatings against MRSA Strains
Iron Man, 2008; www.turbosquid.com
www.turbosquid.com
Why not change the world?

More Related Content

What's hot (6)

Poster presentation [Development of an efficient VIGS system using Tobacco ri...
Poster presentation [Development of an efficient VIGS system using Tobacco ri...Poster presentation [Development of an efficient VIGS system using Tobacco ri...
Poster presentation [Development of an efficient VIGS system using Tobacco ri...
 
In Vitro Diagnostic (IVD) Antibody Development - Creative Biolabs
In Vitro Diagnostic (IVD) Antibody Development - Creative BiolabsIn Vitro Diagnostic (IVD) Antibody Development - Creative Biolabs
In Vitro Diagnostic (IVD) Antibody Development - Creative Biolabs
 
Reverse vaccinology
Reverse vaccinology Reverse vaccinology
Reverse vaccinology
 
Metagenomics Biocuration 2013
Metagenomics Biocuration 2013Metagenomics Biocuration 2013
Metagenomics Biocuration 2013
 
Development of an efficient VIGS system using Tobacco ring spot virus vector ...
Development of an efficient VIGS system using Tobacco ring spot virus vector ...Development of an efficient VIGS system using Tobacco ring spot virus vector ...
Development of an efficient VIGS system using Tobacco ring spot virus vector ...
 
AMR Collaborative Grants at the University of Bristol
AMR Collaborative Grants at the University of BristolAMR Collaborative Grants at the University of Bristol
AMR Collaborative Grants at the University of Bristol
 

Similar to Bio-inspired therapeutics - Ravindra Kane

The Role of Antibiotics and Antibiotic Resistance in Nature
The Role of Antibiotics and Antibiotic Resistance in NatureThe Role of Antibiotics and Antibiotic Resistance in Nature
The Role of Antibiotics and Antibiotic Resistance in Nature
ijtsrd
 
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docxmge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
buffydtesurina
 
A04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
A04_ACSEL 2015 Oral Presentation_Gema Puspa SariA04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
A04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
Gema Puspa Sari
 
Prahlad Rao Latestresume
Prahlad Rao LatestresumePrahlad Rao Latestresume
Prahlad Rao Latestresume
prao123
 
Role of membrane architecture in development of sensitivity to cephalosporin ...
Role of membrane architecture in development of sensitivity to cephalosporin ...Role of membrane architecture in development of sensitivity to cephalosporin ...
Role of membrane architecture in development of sensitivity to cephalosporin ...
Alexander Decker
 
A review on bacterial biofilm formation and disassembly
A review on bacterial biofilm formation and disassemblyA review on bacterial biofilm formation and disassembly
A review on bacterial biofilm formation and disassembly
SSR Institute of International Journal of Life Sciences
 

Similar to Bio-inspired therapeutics - Ravindra Kane (20)

Viral Risk Mitigation - A Global Regulatory Perspective
Viral Risk Mitigation - A Global Regulatory PerspectiveViral Risk Mitigation - A Global Regulatory Perspective
Viral Risk Mitigation - A Global Regulatory Perspective
 
Viral Risk Mitigation - A Global Regulatory Perspective
Viral Risk Mitigation - A Global Regulatory PerspectiveViral Risk Mitigation - A Global Regulatory Perspective
Viral Risk Mitigation - A Global Regulatory Perspective
 
Isolation and identification of protease producing bacteria
Isolation and identification of protease producing bacteriaIsolation and identification of protease producing bacteria
Isolation and identification of protease producing bacteria
 
Molecular farming
Molecular farmingMolecular farming
Molecular farming
 
The Role of Antibiotics and Antibiotic Resistance in Nature
The Role of Antibiotics and Antibiotic Resistance in NatureThe Role of Antibiotics and Antibiotic Resistance in Nature
The Role of Antibiotics and Antibiotic Resistance in Nature
 
PEGS Boston the essential protein engineering summit
PEGS Boston the essential protein engineering summitPEGS Boston the essential protein engineering summit
PEGS Boston the essential protein engineering summit
 
PEGS China 2015 Final Agenda
PEGS China 2015 Final AgendaPEGS China 2015 Final Agenda
PEGS China 2015 Final Agenda
 
3.5. Genetic modification and cloning
3.5. Genetic modification and cloning3.5. Genetic modification and cloning
3.5. Genetic modification and cloning
 
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docxmge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
mge_a4_study_q4.pdfORIGINAL RESEARCHpublished 12 Octobe.docx
 
Advanced Lab Techniques in Avian Medicine
Advanced Lab Techniques in Avian MedicineAdvanced Lab Techniques in Avian Medicine
Advanced Lab Techniques in Avian Medicine
 
A04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
A04_ACSEL 2015 Oral Presentation_Gema Puspa SariA04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
A04_ACSEL 2015 Oral Presentation_Gema Puspa Sari
 
CHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DC
CHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DCCHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DC
CHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DC
 
Defense against-infectious-disease-1228386458765022-9
Defense against-infectious-disease-1228386458765022-9Defense against-infectious-disease-1228386458765022-9
Defense against-infectious-disease-1228386458765022-9
 
Ppt0000001
Ppt0000001Ppt0000001
Ppt0000001
 
Prahlad Rao Latestresume
Prahlad Rao LatestresumePrahlad Rao Latestresume
Prahlad Rao Latestresume
 
Role of membrane architecture in development of sensitivity to cephalosporin ...
Role of membrane architecture in development of sensitivity to cephalosporin ...Role of membrane architecture in development of sensitivity to cephalosporin ...
Role of membrane architecture in development of sensitivity to cephalosporin ...
 
Rloia Pickettiir
Rloia PickettiirRloia Pickettiir
Rloia Pickettiir
 
A review on bacterial biofilm formation and disassembly
A review on bacterial biofilm formation and disassemblyA review on bacterial biofilm formation and disassembly
A review on bacterial biofilm formation and disassembly
 
Advanced Laboratory Techniques in Poultry Disease Diagnosis
Advanced Laboratory Techniques in Poultry Disease DiagnosisAdvanced Laboratory Techniques in Poultry Disease Diagnosis
Advanced Laboratory Techniques in Poultry Disease Diagnosis
 
Microbilogy
MicrobilogyMicrobilogy
Microbilogy
 

More from World Economic Forum

The Global Financial Context Fastfacts
The Global Financial Context FastfactsThe Global Financial Context Fastfacts
The Global Financial Context Fastfacts
World Economic Forum
 
Augmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyreAugmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyre
World Economic Forum
 
Preventing and Treating Chronic Disease - Francis Collins
Preventing and Treating Chronic Disease - Francis CollinsPreventing and Treating Chronic Disease - Francis Collins
Preventing and Treating Chronic Disease - Francis Collins
World Economic Forum
 

More from World Economic Forum (20)

What are mega-regional trade agreements?
What are mega-regional trade agreements?What are mega-regional trade agreements?
What are mega-regional trade agreements?
 
The Global Financial Context Fastfacts
The Global Financial Context FastfactsThe Global Financial Context Fastfacts
The Global Financial Context Fastfacts
 
Latin America Context fast facts
Latin America Context fast factsLatin America Context fast facts
Latin America Context fast facts
 
East Asia Context fast facts
East Asia Context fast factsEast Asia Context fast facts
East Asia Context fast facts
 
Health Context fast facts
Health Context fast factsHealth Context fast facts
Health Context fast facts
 
Resource Context fast facts
Resource Context fast factsResource Context fast facts
Resource Context fast facts
 
Europe Context fast facts
Europe Context fast factsEurope Context fast facts
Europe Context fast facts
 
Financial Context fast facts
Financial Context fast factsFinancial Context fast facts
Financial Context fast facts
 
Arab World Context
Arab World ContextArab World Context
Arab World Context
 
Smart Phones, Smart Farming - Wim Bastiaanssen
Smart Phones, Smart Farming - Wim BastiaanssenSmart Phones, Smart Farming - Wim Bastiaanssen
Smart Phones, Smart Farming - Wim Bastiaanssen
 
Managing Catastrophic Risks - Satoru Nishikawa
Managing Catastrophic Risks - Satoru NishikawaManaging Catastrophic Risks - Satoru Nishikawa
Managing Catastrophic Risks - Satoru Nishikawa
 
Our Data, Ourselves - Ramayya Krishnan
Our Data, Ourselves - Ramayya Krishnan Our Data, Ourselves - Ramayya Krishnan
Our Data, Ourselves - Ramayya Krishnan
 
New Frontiers: Optogenetics - I-han Chou
New Frontiers: Optogenetics - I-han Chou New Frontiers: Optogenetics - I-han Chou
New Frontiers: Optogenetics - I-han Chou
 
Robotics in Medical Care - Howie Choset
Robotics in Medical Care - Howie Choset Robotics in Medical Care - Howie Choset
Robotics in Medical Care - Howie Choset
 
Augmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyre Augmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyre
 
Persuasive Gaming - Ian Bogost
Persuasive Gaming -  Ian BogostPersuasive Gaming -  Ian Bogost
Persuasive Gaming - Ian Bogost
 
Augmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyreAugmented Reality - Blair MacIntyre
Augmented Reality - Blair MacIntyre
 
Global Confidence Index
Global Confidence IndexGlobal Confidence Index
Global Confidence Index
 
Global Leadership Fellows Programme 2011
Global Leadership Fellows Programme 2011Global Leadership Fellows Programme 2011
Global Leadership Fellows Programme 2011
 
Preventing and Treating Chronic Disease - Francis Collins
Preventing and Treating Chronic Disease - Francis CollinsPreventing and Treating Chronic Disease - Francis Collins
Preventing and Treating Chronic Disease - Francis Collins
 

Recently uploaded

Artificial Intelligence: Facts and Myths
Artificial Intelligence: Facts and MythsArtificial Intelligence: Facts and Myths
Artificial Intelligence: Facts and Myths
Joaquim Jorge
 

Recently uploaded (20)

Workshop - Best of Both Worlds_ Combine KG and Vector search for enhanced R...
Workshop - Best of Both Worlds_ Combine  KG and Vector search for  enhanced R...Workshop - Best of Both Worlds_ Combine  KG and Vector search for  enhanced R...
Workshop - Best of Both Worlds_ Combine KG and Vector search for enhanced R...
 
Presentation on how to chat with PDF using ChatGPT code interpreter
Presentation on how to chat with PDF using ChatGPT code interpreterPresentation on how to chat with PDF using ChatGPT code interpreter
Presentation on how to chat with PDF using ChatGPT code interpreter
 
Slack Application Development 101 Slides
Slack Application Development 101 SlidesSlack Application Development 101 Slides
Slack Application Development 101 Slides
 
[2024]Digital Global Overview Report 2024 Meltwater.pdf
[2024]Digital Global Overview Report 2024 Meltwater.pdf[2024]Digital Global Overview Report 2024 Meltwater.pdf
[2024]Digital Global Overview Report 2024 Meltwater.pdf
 
Advantages of Hiring UIUX Design Service Providers for Your Business
Advantages of Hiring UIUX Design Service Providers for Your BusinessAdvantages of Hiring UIUX Design Service Providers for Your Business
Advantages of Hiring UIUX Design Service Providers for Your Business
 
The 7 Things I Know About Cyber Security After 25 Years | April 2024
The 7 Things I Know About Cyber Security After 25 Years | April 2024The 7 Things I Know About Cyber Security After 25 Years | April 2024
The 7 Things I Know About Cyber Security After 25 Years | April 2024
 
Driving Behavioral Change for Information Management through Data-Driven Gree...
Driving Behavioral Change for Information Management through Data-Driven Gree...Driving Behavioral Change for Information Management through Data-Driven Gree...
Driving Behavioral Change for Information Management through Data-Driven Gree...
 
Exploring the Future Potential of AI-Enabled Smartphone Processors
Exploring the Future Potential of AI-Enabled Smartphone ProcessorsExploring the Future Potential of AI-Enabled Smartphone Processors
Exploring the Future Potential of AI-Enabled Smartphone Processors
 
How to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected WorkerHow to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected Worker
 
Real Time Object Detection Using Open CV
Real Time Object Detection Using Open CVReal Time Object Detection Using Open CV
Real Time Object Detection Using Open CV
 
From Event to Action: Accelerate Your Decision Making with Real-Time Automation
From Event to Action: Accelerate Your Decision Making with Real-Time AutomationFrom Event to Action: Accelerate Your Decision Making with Real-Time Automation
From Event to Action: Accelerate Your Decision Making with Real-Time Automation
 
Artificial Intelligence: Facts and Myths
Artificial Intelligence: Facts and MythsArtificial Intelligence: Facts and Myths
Artificial Intelligence: Facts and Myths
 
The Role of Taxonomy and Ontology in Semantic Layers - Heather Hedden.pdf
The Role of Taxonomy and Ontology in Semantic Layers - Heather Hedden.pdfThe Role of Taxonomy and Ontology in Semantic Layers - Heather Hedden.pdf
The Role of Taxonomy and Ontology in Semantic Layers - Heather Hedden.pdf
 
Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...
Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...
Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...
 
Handwritten Text Recognition for manuscripts and early printed texts
Handwritten Text Recognition for manuscripts and early printed textsHandwritten Text Recognition for manuscripts and early printed texts
Handwritten Text Recognition for manuscripts and early printed texts
 
Data Cloud, More than a CDP by Matt Robison
Data Cloud, More than a CDP by Matt RobisonData Cloud, More than a CDP by Matt Robison
Data Cloud, More than a CDP by Matt Robison
 
08448380779 Call Girls In Greater Kailash - I Women Seeking Men
08448380779 Call Girls In Greater Kailash - I Women Seeking Men08448380779 Call Girls In Greater Kailash - I Women Seeking Men
08448380779 Call Girls In Greater Kailash - I Women Seeking Men
 
04-2024-HHUG-Sales-and-Marketing-Alignment.pptx
04-2024-HHUG-Sales-and-Marketing-Alignment.pptx04-2024-HHUG-Sales-and-Marketing-Alignment.pptx
04-2024-HHUG-Sales-and-Marketing-Alignment.pptx
 
What Are The Drone Anti-jamming Systems Technology?
What Are The Drone Anti-jamming Systems Technology?What Are The Drone Anti-jamming Systems Technology?
What Are The Drone Anti-jamming Systems Technology?
 
08448380779 Call Girls In Diplomatic Enclave Women Seeking Men
08448380779 Call Girls In Diplomatic Enclave Women Seeking Men08448380779 Call Girls In Diplomatic Enclave Women Seeking Men
08448380779 Call Girls In Diplomatic Enclave Women Seeking Men
 

Bio-inspired therapeutics - Ravindra Kane