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National Strategy for Improving Outcomes for Sudden Cardiac Arrest in Singapore A/Prof Marcus Ong Consultant, Senior Medical Scientist & Director of Research Department of Emergency Medicine Singapore General Hospital Adjunct Associate Professor Duke-NUS Graduate Medical School Office of Research Prepared for the Advisory Committee on National Coronary Heart Disease Strategy.
 
What is the Epidemiology of Out-of-Hospital Cardiac Arrest in Thailand? ,[object Object],[object Object],[object Object],[object Object]
Characteristics of  Cardiac Arrest Patients Data from the Cardiac Arrest and Resuscitation Epidemiology in Singapore, 2001-2002
CARE Study ,[object Object],[object Object],[object Object],[object Object]
CARE Study ,[object Object],[object Object],[object Object],[object Object]
Multi-Level Efforts Resuscitation Centers of Excellence •  Hypothermia •  24/7 Revascularization •  ICD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Lay Public First Responder EMS Hospital Survival
The Take Heart Approach
Treatment Impact on Outcomes 5 – 10% Rapid cooling, coronary vessel clearing and implanted defibrillators in the hospital 4 – 6% Circulation enhancement by EMS and hospital personnel 4 – 6% Improved quality CPR by EMS 4 – 6% Rapid AED use 2 – 5% Bystander CPR Expected Survival Improvement Intervention Resuscitation Strategies and Their Impacts
Chain of Survival Courtesy of Life Support Training Centre, Singapore General Hospital
Early Access ,[object Object],[object Object],[object Object],[object Object],[object Object]
Early Access CARE Study: EMS Response Time Time  (Mins) Patient collapsed Ambulance called 10.6 Ambulance dispatched 0.7 Ambulance arrived at location 9.5 Ambulance arrived at patient’s side 2.4 CPR Started 1.8 1st shock given 2.3 ROSC 15.6 Arrival at ED 3.2 46.1
DISCUSSION National EMS access number: 995 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DISCUSSION ,[object Object]
[object Object],[object Object],[object Object],[object Object],DISCUSSION
DISCUSSION Number of Ambulances/population
[object Object],[object Object],[object Object],RECOMMENDATIONS
[object Object],[object Object],[object Object],[object Object],[object Object],RECOMMENDATIONS
 
 
PADS I Study
PADS I Study Number of cardiac arrest cases by hour
 
 
IMPROVED RESPONSE TIMES WITH MOTORCYCLE BASED FAST RESPONSE PARAMEDICS IN AN URBAN SETTINGS Ong Marcus, MBBS, FRCS Ed (A&E) Registrar, Department of Emergency Medicine, Singapore General Hospital Chan YH, Phd Head Biostatistics, Clinical Trials and Epidemiology Research Unit, Ministry of Health A/P V Anatharaman, MBBS, MRCP, FRCS Ed (A&E), FAMS Senior Consultant and Head, Department of Emergency Medicine, SGH Clinical Associate Professor, Faculty of Medicine, NUS introduction aims/objectives methods results conclusions Pre-hospital response intervals are known to be an important factor in the level of care provided by any Emergency Medical System. In big cities, response intervals are known to be long due to traffic and accessibility problems. To see if response intervals can be improved with motorcycle based Fast Response Paramedics (FRP) compared with standard ambulances in an urban setting. A prospective, observational study. Simultaneous dispatch of motorcycles based FRP’s equipped with Automated External Defibrillators and standard ambulances for cardiac arrest, cardiac, respiratory conditions and road traffic accidents. 48 consecutive ambulance runs were recorded. Locations involved: home (41.7%), work (29.2%), road accident (20.8%) and others (8.3%) Ambulances took on average 4.96 minutes longer than motorcycles to respond (p<0.001, 95% CI 2.61 to 7.31). Adjusting (via multiple regression) for the day of the week, location, station, traffic and case, ambulances took on the average 4.71 (p<0.001, 95% CI 2.45 to 6.98) minutes longer to respond. Improvements in response times were greater when overall response times were longer (weekdays, residential/office location, moderate or heavy traffic). Use of motorcycle based paramedics allow for faster response intervals and earlier interventions, especially early defibrillation in cardiac arrest. Larger follow-up studies are planned to assess the impact of implementation of more FRP’s on mortality and morbidity.
Early Cardio-Pulmonary Resuscitation (CPR) CARE Study: Bystander CPR
Early CPR Lateef et al 2001 SGH ASM
Quality of CPR: Pocket QCPR feedback device for use with manual CPR (CPREZY)
Defibrillator pads incorporating an accelerometer for QCPR feedback (Zoll E series defibrillation pads)
Defibrillator screen display incorporating QCPR feedback indicators (Zoll E series)
[object Object],[object Object],[object Object],[object Object],RECOMMENDATIONS
[object Object],[object Object],[object Object],RECOMMENDATIONS
Public Access Defibrillation in Singapore: What is the Geographic-Time Distribution of Cardiac Arrests in Singapore?   (PADS I Study) PADS I Study Early Defibrillation
PADS I Study
85.77 12,436 70.35 (19.41) 32 27 Ghim Moh 30.82 90,864 64.52 (18.57) 84 12 Clementi 32.31 60,870 57.15 (20.11) 59 54 Sengkang 31.77 31,481 62.88 (21.88) 30 32 Towner 63.34 19,999 52.71 (24.31) 38 47 Bedok  (Bedok Reservoir) 81.47 11,047 63.32 (14.55) 27 05 South Bridge Road / Kreta Ayer 108.10 8,017 61.37 (16.72) 26 21 Jalan Besar 163.24 11,639 64.43 (22.41) 57 15 Alexandra (Bukit Merah/Redhill) Arrest Rate per year over 3 years (per 100,000 population) Esitmated Population base (2000 census) Mean Age of arrests(SD) N Postal code Area
Early Defibrillation Breakdown of Location of Cardiac Arrest Cases
Defibrillation by Health Care Providers Breakdown of Location of Cardiac Arrest Cases : Many are within reach of a GP/Clinic (CARE Study Phase I & II - 1 Oct 2001 to 14 Oct 2004)
1995: First Five Years of Pre-Hospital Automatic Defibrillation Project in Singapore
[object Object],[object Object],[object Object],RECOMMENDATIONS
[object Object],[object Object],[object Object],RECOMMENDATIONS
Advanced Life Support (ALS) ,[object Object],[object Object],Early Advanced Care
 
[object Object],[object Object],[object Object],RECOMMENDATIONS
Dr Marcus Ong  MBBS (Singapore), FRCS Ed (A&E), MPH, FAMS Consultant, Director of Research and Senior Medical Scientist Department of Emergency Medicine Singapore General Hospital
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],RECOMMENDATIONS
“ “ A Prospective Clinical Study Comparing Controlled Therapeutic Hypothermia Post-Cardiac Arrest Using External and Internal Cooling to Standard Intensive Care Unit Therapy” 
 
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Conference Secretariat: Tel: (65)  6 379   5261/ 6 379 5259 Fax: (65) 6 475 2077  Email: admin@ icem2010.org
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National Strategy for Improving Outcomes for Sudden Cardiac Arrest in Singapore

  • 1. National Strategy for Improving Outcomes for Sudden Cardiac Arrest in Singapore A/Prof Marcus Ong Consultant, Senior Medical Scientist & Director of Research Department of Emergency Medicine Singapore General Hospital Adjunct Associate Professor Duke-NUS Graduate Medical School Office of Research Prepared for the Advisory Committee on National Coronary Heart Disease Strategy.
  • 2.  
  • 3.
  • 4. Characteristics of Cardiac Arrest Patients Data from the Cardiac Arrest and Resuscitation Epidemiology in Singapore, 2001-2002
  • 5.
  • 6.
  • 7.
  • 8. The Take Heart Approach
  • 9. Treatment Impact on Outcomes 5 – 10% Rapid cooling, coronary vessel clearing and implanted defibrillators in the hospital 4 – 6% Circulation enhancement by EMS and hospital personnel 4 – 6% Improved quality CPR by EMS 4 – 6% Rapid AED use 2 – 5% Bystander CPR Expected Survival Improvement Intervention Resuscitation Strategies and Their Impacts
  • 10. Chain of Survival Courtesy of Life Support Training Centre, Singapore General Hospital
  • 11.
  • 12. Early Access CARE Study: EMS Response Time Time (Mins) Patient collapsed Ambulance called 10.6 Ambulance dispatched 0.7 Ambulance arrived at location 9.5 Ambulance arrived at patient’s side 2.4 CPR Started 1.8 1st shock given 2.3 ROSC 15.6 Arrival at ED 3.2 46.1
  • 13.
  • 14.
  • 15.
  • 16. DISCUSSION Number of Ambulances/population
  • 17.
  • 18.
  • 19.  
  • 20.  
  • 22. PADS I Study Number of cardiac arrest cases by hour
  • 23.  
  • 24.  
  • 25. IMPROVED RESPONSE TIMES WITH MOTORCYCLE BASED FAST RESPONSE PARAMEDICS IN AN URBAN SETTINGS Ong Marcus, MBBS, FRCS Ed (A&E) Registrar, Department of Emergency Medicine, Singapore General Hospital Chan YH, Phd Head Biostatistics, Clinical Trials and Epidemiology Research Unit, Ministry of Health A/P V Anatharaman, MBBS, MRCP, FRCS Ed (A&E), FAMS Senior Consultant and Head, Department of Emergency Medicine, SGH Clinical Associate Professor, Faculty of Medicine, NUS introduction aims/objectives methods results conclusions Pre-hospital response intervals are known to be an important factor in the level of care provided by any Emergency Medical System. In big cities, response intervals are known to be long due to traffic and accessibility problems. To see if response intervals can be improved with motorcycle based Fast Response Paramedics (FRP) compared with standard ambulances in an urban setting. A prospective, observational study. Simultaneous dispatch of motorcycles based FRP’s equipped with Automated External Defibrillators and standard ambulances for cardiac arrest, cardiac, respiratory conditions and road traffic accidents. 48 consecutive ambulance runs were recorded. Locations involved: home (41.7%), work (29.2%), road accident (20.8%) and others (8.3%) Ambulances took on average 4.96 minutes longer than motorcycles to respond (p<0.001, 95% CI 2.61 to 7.31). Adjusting (via multiple regression) for the day of the week, location, station, traffic and case, ambulances took on the average 4.71 (p<0.001, 95% CI 2.45 to 6.98) minutes longer to respond. Improvements in response times were greater when overall response times were longer (weekdays, residential/office location, moderate or heavy traffic). Use of motorcycle based paramedics allow for faster response intervals and earlier interventions, especially early defibrillation in cardiac arrest. Larger follow-up studies are planned to assess the impact of implementation of more FRP’s on mortality and morbidity.
  • 26. Early Cardio-Pulmonary Resuscitation (CPR) CARE Study: Bystander CPR
  • 27. Early CPR Lateef et al 2001 SGH ASM
  • 28. Quality of CPR: Pocket QCPR feedback device for use with manual CPR (CPREZY)
  • 29. Defibrillator pads incorporating an accelerometer for QCPR feedback (Zoll E series defibrillation pads)
  • 30. Defibrillator screen display incorporating QCPR feedback indicators (Zoll E series)
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  • 33. Public Access Defibrillation in Singapore: What is the Geographic-Time Distribution of Cardiac Arrests in Singapore? (PADS I Study) PADS I Study Early Defibrillation
  • 35. 85.77 12,436 70.35 (19.41) 32 27 Ghim Moh 30.82 90,864 64.52 (18.57) 84 12 Clementi 32.31 60,870 57.15 (20.11) 59 54 Sengkang 31.77 31,481 62.88 (21.88) 30 32 Towner 63.34 19,999 52.71 (24.31) 38 47 Bedok (Bedok Reservoir) 81.47 11,047 63.32 (14.55) 27 05 South Bridge Road / Kreta Ayer 108.10 8,017 61.37 (16.72) 26 21 Jalan Besar 163.24 11,639 64.43 (22.41) 57 15 Alexandra (Bukit Merah/Redhill) Arrest Rate per year over 3 years (per 100,000 population) Esitmated Population base (2000 census) Mean Age of arrests(SD) N Postal code Area
  • 36. Early Defibrillation Breakdown of Location of Cardiac Arrest Cases
  • 37. Defibrillation by Health Care Providers Breakdown of Location of Cardiac Arrest Cases : Many are within reach of a GP/Clinic (CARE Study Phase I & II - 1 Oct 2001 to 14 Oct 2004)
  • 38. 1995: First Five Years of Pre-Hospital Automatic Defibrillation Project in Singapore
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  • 44. Dr Marcus Ong MBBS (Singapore), FRCS Ed (A&E), MPH, FAMS Consultant, Director of Research and Senior Medical Scientist Department of Emergency Medicine Singapore General Hospital
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  • 47. “ “ A Prospective Clinical Study Comparing Controlled Therapeutic Hypothermia Post-Cardiac Arrest Using External and Internal Cooling to Standard Intensive Care Unit Therapy” 
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  • 50. Conference Secretariat: Tel: (65) 6 379 5261/ 6 379 5259 Fax: (65) 6 475 2077 Email: admin@ icem2010.org
  • 52. See You in Singapore!