3. OBJECTIVES
• By the end of this session you should be able to
differentiate between most of the patterns in
histopathology.
HOPEFULLY!!!!
4.
5.
6. WHAT IS TRABECULAE?
• A small supporting beam or bar.
• Any of the supporting strands of connective tissue
projecting into an organ and constituting part of
the framework of that organ.
• Any of the fine spicules forming a network in cancellous
bone.
7. TRABECULAR PATTERN
• In cord-like arrays separated by fibrous septa in Long nests
and cords of cell groups
• Two cell-thick (microtrabecular pattern)
• Eight to Ten cell-thick (macrotrabecular pattern)
• Cells arranged perpendicular to the longest axis.
16. WHAT IS ALVEOLUS?
• a small cavity or pit
• a socket in the jaw for a tooth
• a small air-containing compartment of the lungs in
which the bronchioles terminate and from which
respiratory gases are exchanged with the
pulmonary capillaries
• an acinus of a compound gland
• a cell of a honeycomb
17. ALVEOLAR PATTERN
• Tumor cells grow in nests or clusters separated by fibrous
septa
• In little sacs or nests or nested structure
20. WHAT IS HERRING?
• name given to a type of fish found in the shallow
waters of north pacific and north atlantic.
21. HERRING BONE
• The Herring Bone is nothing but the name given to
the skeleton of the Herring fish
22. HERRING BONE PATTERN
• arrangement in columns of short parallel lines
with all the lines in one column sloping one way
and lines in adjacent columns sloping the other
way.
26. WHAT IS STORIFORM?
• having an irregularly whorled pattern somewhat
like that of a straw mat.
• Having a cartwheel pattern, such as spindle cells
having elongated nuclei radiating from a center.
27.
28. STORIFORM PATTERN
• Cartwheel pattern - spindle cells with elongated nuclei
radiating from a center point
• Cellular spindled lesion with whorls as opposed to parallel
fasicles or right angle bundles
33. WHAT IS A FASCICLE?
• a section of a book or set of books being published
in installments as separate pamphlets or volumes.
• a small bundle, tight cluster, or the like.
• a close cluster, as of flowers or leaves.
• a small bundle of nerve or muscle fibers.
40. WHAT IS CRIBRIFORM?
• Sieve-like; containing many perforations.
• describing a structure with many perforations or
punctures, as in the cribriform plate of the ethmoid
bone.
• descriptive term referring to a sieve-
like histologic pattern, in which sheets of epithelial cells
are punctuated by gland-like spaces
49. WHAT IS PAPPILAE?
• any small, nipplelike process or projection.
• one of certain small protuberances concerned with
the senses of touch,taste, and smell:
the papillae of the tongue.
• a small vascular process at the root of a hair.
• a papule or pimple.
50. PAPILLARY PATTERN
• complex, branching, and randomly oriented, with
a central fibrovascular core and a single or
stratified lining
63. HOBNAIL PATTERN
• Resembling a large headed nail used for shoes
• Epithelial or endothelial cells round up and protrude into
the lumen as little bumps.
66. WHAT IS ROSSETTE?
• an ornament usually made of material gathered or pleated so as
to resemble a rose and worn as a badge of office, as evidence of
having won a decoration (as the Medal of Honor), or as trimming
• a disk of foliage or a floral design usually in relief used as a
decorative motif
• a cluster of leaves in crowded circles or spirals arising basally
from a crown (as in the dandelion) or apically from an axis with
greatly shortened internodes (as in many tropical palms)
• rose windows found in gothic cathedrals
67.
68. ROSSETTE IN PATHOLOGY
• A rosette is halo or "spoke-wheel" arrangement of
cells around a central structure (which can be a
lumen or cytoplasmic processes).
73. MICROCYSTIC PATTERN
• consisting of a loose network of cystic spaces lined
by flattened epithelial cells Resembling a network
or net-like array
• Microcystic or honeycomb appearance
75. WHAT IS A FOLLICLE?
• A small bodily cavity or sac.
• A crypt or minute cul-de-
sac or lacuna, such as the depression in the skin from whi
ch the hair emerges.
• An ovarian follicle.
• A spherical mass of cells usually containing
a cavity.
• Botany A dry, single chambered fruit that
splits along only one seam to release
its seeds, as inlarkspur and milkweed.
Tumor cells in a medullary carcinoma have anaplastic nuclei, prominent nucleoli, and ill-defined cell borders giving the appearance of a syncytial pattern