Nutrition for Heart
Health: Focus on
Good & Bad Fats
Geeta Sikand: MA, RD, CLS,FNLA,CDE
Associate Clinical Professor of Medicine:
Cardiology: UC Irvine
Consultant Dietitian
June 29, 2012
Objectives/Presentation Outline
1) Coronary heart disease risk factors in
Asian Indians
2) Evidence based diet & lifestyle
recommendations to lower heart
disease risk in Asian Indians
3) Good and bad fats within the context
of a heart healthy diet
South Asia at Health Crossroads
World Bank Report: February 2011
Asian-Indians (India, Pakistan, Bangladesh,
Sri lanka & Nepal) 3 X more likely to develop
diabetes.
Diabetes doubles risk of heart disease in men
& quadruples risk in women.
First heart attack in Asian Indians: six years
younger versus rest of the world (53 vs. 59
years)
www.worldbank.org/sarncdreport
Are Women at Risk for Heart
Disease?
Heart disease is ALSO the leading cause
of death in women in every major
developed country e.g. US and also in
most emerging economies.
The myth that heart disease is only a
“man’s disease” has been debunked.
Risk Factors for
Heart Disease and Stroke
What are “risk factors” ?
Behaviors or conditions that increase
your chances of developing a disease.
Example: Being inactive is a
risk factor for heart disease
and stroke.
Metabolic Syndrome
Primary Cause of Increased CHD Risk in Asian
Indians
Higher prevalence of high triglycerides, low HDL-C,
glucose intolerance & central obesity.
MetS increases risk for heart disease at any LDL
level
Pre-diabetes or Insulin Resistance Syndrome
Enas EA. Brit J of Diabetes and Vascular Dis 2005
Metabolic Syndrome: Diagnostic
Criteria: 3 or more
Central obesity (waist circumference)
• Men > 40 inches (Asian Indians 35.4”)
• Women > 35 inches (Asian Indians 31.5”)
↑ Triglycerides > 150
↓ HDL men < 40 women < 50
↑ Blood Pressure >130/85
Impaired fasting glucose: 100-125
Grundy SM et al Circulation. 2004
Goals for Heart Health
Control the ABC’s:
A1C
Blood pressure
Cholesterol/lipids
Maintain a desirable weight
Stop smoking
Sikand Geeta 2011 2nd edition. “Preventing Heart Disease in Asian
Indians: Diet & Lifestyle Recommendations” in “AAPI’s Guide to
Nutrition, Health & Diabetes”
Weight Loss Reduces Risk
Improves blood cholesterol
Lowers total and LDL cholesterol
Lowers triglycerides
Raises HDL cholesterol
Reduces blood pressure
Makes your insulin work better
(improves effectiveness in the body)
Lowers blood glucose
AHA 2006 Diet & Lifestyle Recommendations
Achieve a healthy weight
Decrease total fat, saturated fat and trans
fats. Replace with unsaturated fats and oils
Increase intake of omega 3 fatty acids
Increase intake of plant stanol esters
Consume nuts and soy protein
Increase intake of viscous fiber
Lichtenstein et al Circulation 2006
American Heart Association
2020 Dietary Goals
rimary
ruits & Vegetables: ≥ 4.5 cups/day
ish: ≥ two 3.5 oz. servings/week (preferably oily fish)
iber-rich whole grains (≥ 1.1 g of fiber/10 g of CHO: ≥ three 1
oz. equivalent servings per day)
odium: < 1500 mg/day
econdary
ugar-sweetened beverages: ≤ 450 kcal (36 oz.)/week
The Portfolio Eating Plan to lower LDL-C
• NCEP Guidelines:
– Saturated fat < 7% kcal
– Cholesterol < 200 mg/day
• 1.0 g plant sterols/1000 kcal
• 9.8 g viscous fibers/1000 kcal
• 21.4 g soy protein/1000 kcal
• 14 g whole almonds/1000 kcal
• Jenkins DJ, JAMA. 2003
Effect of Portfolio Eating Plan on LDL
Reduction
10 g psyllium (viscous fiber) lowered LDL
6-7%
45 g soy proteins reduced LDL 12.5%
1-2 g plant sterols reduced LDL 13%
10 g almonds lowered LDL-C 1%
Similar to the effect of statins
Jenkins DJ, JAMA. 2003
Look AHEAD Trial: 4 yrs Follow up
Intense Lifestyle Intervention versus Control Group
• n=5,145 59 yrs (45-74 yrs), BMI 36 (>25)
• Diet-lifestyle counseling: RDs
Wt loss −6.15% vs −0.88% (P<.001)
Improved Treadmill fitness (% METS)
12.74% vs 1.96% (P<.001)
A1c level −0.36% vs −0.09% (P<.001)
Greater proportion of intervention group met A1c, BP
& lipid goals versus control group
Arch Intern Med 2010 lookaheadtrial.org.
Is Dietitian Intervention Effective to
Reduce LDL ?
N=74 male veterans, mean age 61 yrs
2-4 dietitian visits (8 weeks)
Reduced LDL -13% ( p<0.001)
50% no longer needed lipid lowering meds
Saved $904 per pt
$1.00 spent on MNT = $4.60 saved in lipid medication
costs
LDL reduction greater with more dietitian visits 12% vs
22 % (p<0.001) with 2 vs 4 visits
Sikand et al. J Am Diet Assoc 1998
Is Dietitian Intervention Effective?
Systematic Review: Amer Diet Assoc
2 to 6 planned visits with a RD over 6-12 weeks
reduced: LDL: 7-22% , TG 11-31%, saturated
fat intake 2-4% & energy intake ( 232 – 710
kcal per day) & body weight.
Initial Dietitian Visit 45 to 90 min
F up Dietitian Visits 30 to 60 min each
Grade 1 Strong
McCoin, Sikand et al J Am Diet Assoc 2008
Raj’s Current Diet & Lifestyle
• Software engineer
• Inactive: works long hours
• High saturated fat intake: High fat
dairy products e.g. paneer
• High refined carbohydrate
consumption – bread, rice, sweets
• Alcohol?
What are Raj’s Goals?
Does he want to see a RD? Lifestyle
intervention program? telephone app?
What diet changes should Raj consider?
Is Raj motivated to lose weight?
Weight loss 10 lbs: improve BP, LDL-C, TG,
HDL-C, A1c, fasting glucose
Recommendations to Lower
Raj’s LDL-C: TLC Diet
Decrease saturated and trans fats, dietary cholesterol
Lose weight
Increase
Total Fiber (20-30 grams a day)
Soluble Fiber (~10 grams a day)
Plant stanol/sterol (2 grams a day)
Activity (30 minutes most days/week)
Sikand G 2011 “Nutrition, Health & Diabetes” AAPI 2nd edition.
Preventing Heart Disease in Asian Indians: Diet & Lifestyle
Recommendations
Lifestyle Changes for Raj to consider
Diet : Keep a food log Exercise
Limit/choose lean meat, Keep a physical activity
poultry (5 - 6oz. day) log
2 or 3 servings of non-fat
or low fat dairy products Begin a walking program
Include fish 2x/week
and gradually increase to
35 minutes per day
Increase fruits &
vegetables Use a pedometer and set
Small serving of nuts
a goal to increase 250
Focus on portion control steps/day up to 10,000
steps
TLC Diet Options for Raj
Increase intake of viscous (soluble) fiber:
10-25g per day
Sources of soluble fiber include:
Oats
Dried beans
Fruits/vegetables (eg.strawberries, bhindi, baingan)
2 tbsp plant sterol/stanol esters
Sources include:
Benecol, Promise activ
Reducing sodium and alcohol intake
TLC Diet Could Reduce Raj’s LDL by
20-30% (WIIFM)
Dietary Dietary LDL chol
component change reduction
Plant sterols 2–3 g/day 6-15%
Saturated fat < 7% calories 5–10%
Dietary cholesterol < 200 mg/day 5%
Soluble fiber 5–10 g/day 5%
Body weight Lose ~10 lb 5%
Total estimated
20-30%
LDL reduction
Sacks FM et al. Circulation 2006;113. Jenkins et al, Curr Opin Lipidol 2000; Weggemans and Trautwein, Eur J Clin
Nutr 2003; Katan et al, May Clin Proc 2003.
Food Components to Reduce Fat
Saturated fatty acids—less than 10% of calories
• Less than 7% reduces risk of CVD further
• Replace with poly- and monounsaturated fatty
acids (not with sugar or refined grain)
Trans fats—as low as possible
Cholesterol—less than 300 mg per day
• Effect small compared to saturated and trans fats
new
• Egg yolks—up to 1 per day new
Aim for 25 – 35 gm Dietary Fiber per day
Starchy beans/lentils: Aim for ½ cup cooked
beans in 3 - 5 meals per week
Oatmeal, oat bran, barley, brown rice, Quinoa
Vegetables and fruits (eat edible skin)
Aim for 2 ½ c. veggies and 2 c. fruits a day
Whole grain breads, crackers and cereals with at
least 5 gm of Dietary Fiber per serving
Psyllium seeds (Metamucil)
Foods Containing Viscous or Soluble
Fiber: 10 – 25 gm/day
Oats
Barley
Lentils (daals)
Legumes (rajma, channa, black eyed beans)
Prunes, Apples
Rye bread, pumpernickel bread
Supplemental fiber: Metamucil® and Citrucel®.
(Not all fiber laxatives lower cholesterol)
Limit Saturated Fats: “Bad” Fats
Raise LDL
Solid at room temperature
Whole milk & whole milk dairy products:
butter, paneer, cheese, cream, ice-cream,
whole milk yogurt, desserts made with whole
milk e.g. khoa, kulfi, kheer
Fatty cuts of lamb, pork, beef, poultry with
skin, lard, bacon, sausage, hotdogs
Palm oil, palm kernel oil and coconut oils
Trans-fats: “Bad” Fats
Raise LDL & Lower HDL
Processing changes vegetable oils into semi-
solid fats e.g. partially hydrogenated fats
Re-use of oil in cooking/frying e.g.
commercially prepared snacks e.g. samosas,
bhajias, chevda, bhel etc
French fries, fried chicken, onion rings
Stick margarine, shortening, vanaspati
Baked goods: cakes, donuts, cookies
Monounsaturated Fats : Good Fats
Lower LDL
May help raise HDL (good) cholesterol.
Olive oil, canola oil, peanut oil
Avocados
Nuts: almonds, peanuts, pecans,
pistachios, hazelnuts
Is EVOO good for cooking?
Omega-6 Polyunsaturated fats: Good
Fats Lower LDL
Lower LDL (bad) cholesterol when used
in place of saturated fat.
Corn oil, safflower oil, sunflower oil
Sunflower seeds
Plant Stanols/Sterols lower LDL-C 10%
Adjunct therapy to diet and medication eg.
Bennecol spread, Smart balance Heart Right
spread, Promise activ spread, fortified in orange
juice & in health bars e.g. Kardea bars
Naturally found in vegetable oils, nuts, legumes,
whole grains, fruits, vegetables; yet in small
amounts, making it difficult to get recommended
amounts
2 Grams of Plant Sterols
150 small apples
83 oranges
210 medium carrot
425 tomatoes
11 cups of peanuts
70 slices of whole grain bread
OR
2 Tbsp Smart Balance® Heart Right Buttery Spread
2 Tbsp Promise activ® Buttery Spread
Phytosterols Added to Foods
Supplemented Foods amount calories
1 Tbsp Benecol® 0.85 g 50-70
1 Benecol® smart chew 0.85 g 20
1 oz Lifetime® LF cheese 0.65 g 30-55
1 c Minute Maid® Heart Wise OJ 1.0 g 110
1.5 slices Oroweat® Whole Grain & Oat Bread 0.4 g 90
1 c Rice Dream® Heart Wise Rice Milk (original or vanilla) 0.65 g 140
1 c Silk Heart Health Vanilla Soymilk 0.65 g 80
1 Tbsp Smart Balance® Heart Right Buttery Spread 1.7 g 45-80
1 Tbsp Promise activTM spread 1.0 g 45-70
VitaMuffin VitaTopsTM Muffin or VitaTopsTM Brownie 0.4 g 100
Omega-3 Fats: Good Fats
Lower Risk of Heart Disease & TG
Two servings (3.5 oz each) of fatty fish per
week are associated with a 30-40% reduced
risk of death from heart attack or stroke
Lower triglycerides
Associated with ↓ sudden death (ACS)
Salmon, mackarel, sardines, rainbow trout,
herring, halibut & albacore tuna
Fish Oil Supplementation
Recommendations
3-4 oz fatty fish/day or
1-3 g omega 3 fatty acids per day (for heart
health and TG lowering)
FDA: 3 g omega 3 fatty acids a day (with no
more than 2 g per day from a dietary
supplement)
Look for 1g fish oil capsules contain
180 mg of EPA and 120 mg DHA
Raising HDL (Good)
Cholesterol
Be physically active
Lose weight if overweight
Decrease refined carbs
Moderate fat intake
Increase monounsaturated fats
Do not smoke
Food Sources
Potassium
Vegetables (potatoes, tomatoes, spinach, broccoli,
acorn squash, collard & mustard greens)
Fruits (grapefruit, orange, banana, watermelon,
strawberries)
Caution for use in those with kidney disease
Magnesium
Vegetables (spinach, broccoli, green beans, tomato
juice; navy and pinto beans)
Whole grains (100% whole wheat bread, crackers)
Other (tofu, halibut)
Decrease Sodium/ Increase
Potassium
Limit sodium from ALL foods to
2,300 mg (~1 tsp. salt) per day or 1500
mg/day (at risk, older, HTN)
Consume potassium rich foods: low fat milk,
milk
fruits and vegetables
Strategies to Lower Salt Intake
o Become aware of salt content in food eg ketchup,
soy sauce, pickles, chutneys. Read labels.
Cook with little or no salt. Refrain from adding salt at
the table
Avoid processed salty foods eg snack mixes bhel,
chevda, nuts
Use spices & lemon instead of salt
Rinse canned foods e.g. beans
Use no-salt-added food products – read labels
2010 US Dietary Guidelines:
Summary
Enjoy your food, but eat less. Reduce calories from solid fats
and added sugars (SoFAS)
Choose foods high in potassium, dietary fiber, calcium & vitamin
D. Make half your plate fruits & vegetables.
Maintain a healthy weight. Perform regular physical activity.
Switch to fat free or low fat milk (1%).
Reduce salt by comparing sodium in foods e.g. soup, bread &
frozen meals & choose foods with lower numbers.
Drink water instead of sweetened beverages.
www.dietaryguidelines.gov
Resources
Preventing Heart Disease in Asian Indians:
Diet & Lifestyle Recommendations”
By Geeta Sikand,MA,RD,CLS,FNLA,CDE,FADA
In “Indian Foods; AAPI’s Guide to Nutrition
Health & Diabetes” 2011 2nd edition
www.aapiusa.org
www.aha.org
Sacks, FM et al. Soy proteins, isoflavones, and cardiovascular health: An American Heart Association science advisory for professionals from the nutrition committee. Circulation 2006; 113. Jenkins et al. Curr Opin Lipidol 2000, Weggemans and Trautwein Eur J Clin Nutr 2003, Katan et al . Mayo Clin Proc 2003. A number of dietary factors have been proven to lower total and LDL cholesterol effectively. Amongst different dietary options, adding plant sterols to the diet is a very effective dietary intervention that can reduce LDL cholesterol by around 6-15% if taken in the recommended amount of 2–3 g/day. In comparison to soy protein, plant sterols have more than double the effect in reducing cholesterol levels whereby the daily dose is much lower.
To reach the recommended plant sterol intake for cholesterol-lowering of 2 /day, an individual would need to consume an enormous amount of typical foods such as fruits, vegetables or bread. One to two servings of Promise ® SuperShots ® or Promise activ ® Spread provide the recommended 2 grams of plant sterols per day for individuals with elevated cholesterol levels.
Safety: considered GRAS. ADI is 130 mg per kg. 110 lb person can have up to 6.5 grams daily