In this session we discussed key lessons learned for scientists and start-ups to successfully bring to market evidence-based innovative solutions. We will also present non-dilutive funding opportunities and commercialization resources offered through the US small business research programs. A scientist and inventor turned serial entrepreneur will wrap-up the day sharing insights from his previous venture–funded by the NIMH and sold to McKesson–and his current strategy and vision. --Chair: Dr. Alison Fenney, Executive Director of the Neurotechnology Industry Organization --Dr. Margaret Grabb, SBIR/STTR Program Director at the National Institute of Mental Health (NIMH) --Dr. Rex Jakobovits, Founder of Vivalog Technologies and Experiad Learn more at sharpbrains.com

1. Best practices to fund, develop and
commercialize evidence-based innovation

2. Best practices to fund, develop and commercialize
evidence-based innovation
Chaired by: Dr. Alison Fenney,
Executive Director,
Neurotechnology Industry Organization
Dr. Margaret Grabb,
SBIR/STTR Program Director,
National Institute of Mental Health
Dr. Rex Jakobovits,
Founder,
Vivalog Technologies and Experiad

3. Small Business Research
Programs at NIMH
Margaret C. Grabb, Ph.D.
SBIR/STTR Program Director
December 7, 2016

4. SBIR/STTR Program Overview
4

5. SBIR/STTR Program- 3 Phases
5

6. SBIR/STTR Program- 3 Phases
6

7. SBIR/STTR Program- 3 Phases
7

8. SBIR/STTR Program- 3 Phases
8

9. Commercialization Readiness Pilot (CRP)
9

10. Technical Assistance Programs
NIH Provides Contract Services to Help Small
Businesses with Commercialization
• Phase I awardees:
• Niche Assessment Program: market analysis reports
• I-Corp Program: 8 week program with business expert
instructors in technology domain
• Commercialization Assistance Program:
• Phase II awardees:
 For emerging and seasoned companies
 Business, strategic planning
 Training workshops, individual mentoring and consulting
sessions

11. NIH SBIR/STTR Budgets
11
• Phase I guidelines: $150,000; 6 months (SBIR), 1 year (STTR)
• Phase I cap: $225,000; 2 years
• Phase II guidelines: $1 Million; 2 years
• Phase II cap: $1.5 Million; 3 years
• Budget waiver
If topic is approved as a budget waiver topic (Appendix A
of Grant topic list), budget requested can be higher than the cap.
https://sbir.nih.gov/sites/default/files/NIH_Topics_for_Budget_Waivers.pdf
Contact program staff before submitting the application.

12. SBIR/STTR Programs at NIMH
12
NIMH mission
 to transform the understanding and treatment of mental illnesses
through basic and clinical research, paving the way for
prevention, recovery and cure.
Diversity of Portfolio
 From molecular tools to e-health tools
 Community served (neuroscience researchers, clinical
researchers, clinicians, patients, caregivers)
Innovation in Program to Meet Needs of NIMH
 Promoting academic-private sector teams
 First SBIR Phase IIb opportunity in the federal government
developed at NIMH

13. NIMH SBIR/STTR Programs: Portfolio
13

14. NIMH SBIR/STTR Programs: Portfolio
14

15. NIMH SBIR/STTR Programs: IT Health
15

16. NIMH SBIR/STTR Programs
IT Health in Detail
• Passive monitoring techniques (i.e. GPS, accelerometer, internet usage)
to predict, prevent and provide real time interventions Cogito Corp.
• Platforms to train and disseminate evidence-based practices to clinicians
to increase knowledge and adherence- Center for Social Innovation
• Online interventions using mobile platforms to extend the reach of
Interventions- Recovery Record Research, Inc.
• Clinician rated computerized assessments, including remote assessments
- Telesage, Inc.; Behavioral Imaging Solutions
• Biofeedback, using EEG or other CNS measures- Think Now, Inc.
• Platforms to measure medication adherence (injectable sensor, chemical
sensor and mobile app)- Xhale, Inc.

17. NIMH SBIR/STTR Programs
Please contact me if interested in learning more
about the NIMH SBIR/STTR Programs
Meg Grabb, NIMH
301-443-3563
NIH SBIR website:
https://sbir.nih.gov/

18. SBIR as Seed Capital:
The Journey to Getting Acquired
SharpBrains Summit, Dec 7, 2015
Rex Jakobovits, PhD
President, Experiad Solutions
rex@experiad.com

29. $5K
$11K

30. $5K
$11K
$28K
$37K
2004

31. $5K
$11K
$28K
$37K
$55K each

32. $5K
$11K
$28K
$37K
$55K each
$280K
2007-08
+ 9 more

33. $5K
$11K
$28K
$37K
$55K each
$280K
+ 9 more

34. Vivalog Acquired

35. Vivalog Acquired
My Last Day, July 2013
Todd Rex
Rex Leaves

44. (but not too much)

47. McKesson Due Dilly: 897 requests!
• “detailed list by customer of committed
development projects (contractual or oral)”;
• “agreements relating to confidentiality”;
• “schedule of all fixed assets and other
property”;
• “copies of all policies relating to…”

57. Q&A

58. Thank you to all Participants!

59. Sponsors
Thank you to all Speakers & Sponsors!

60. To learn more, visit sharpbrains.com