Multi parameter vitals modular monitoring technology and proactive medical decision support systems

1. Preventive vital signals monitoring
during strenuous physical activities

2. Company
 Skolkovo resident;
 Nominated top 100 in Russia`s fast-growing high-tech companies national
rating
Main area of activity:
 Development of non-invasive biosensors for dynamic monitoring of vital
signals and health control;
 Development of object recognition methods and 3D vision technology;
 Development of training systems for rehabilitation of the musculoskeletal
system.
Company’s products are aimed at home and professional application in
REHABILITATION FITNESS SPORTS and HOME TELEMEDICINE
All vital signals received are integrated into one cloud environment.

3. Personal medical assistant
A portable smart preventive monitoring biosensor platform that allows to
correlate data received from a variety of sensors in a noisy environment (“on-the-go”
mode).
 Product: wearable t-shirt/cuff with a set of biosensors and a smartphone;
 Service: non-invasive diagnostics “on-the-go”
 Linked with the cloud service with access to user’s personal cabinet;
 Notifications sent to personal doctor/relatives in case of critical state;
 Patient condition prediction based on the changes in vital signals.
 Vital signals: include cardiogram, level of lactic acid/glucose, blood pressure

5. Wireless highly selective lactic acid biosensor
based on a nanostructured catalyst
 Allows to solve the problem of untimely or inaccurate
diagnosis often leading up to DISABILITY and/or DEATH;
 "Prussian Blue“ is used as the catalyst with polymer
immobilization of the organic enzyme;
 “Prussian Blue” is nanostructred on the electrode surface,
which greatly improves the biosensor sensitivity and
selectivity;
 Mechatronic, microfluidic design of the sweat collector with
micropumps analysis and wireless data transmission to a
smartphone;
 The biosensor can be used as part of a at-home
musculoskeletal rehabilitation system for control of the
critical levels of physical activity.
Competitive Advantages:
Non-invasive Autonomous Ease to use
Personal health management

6. Noise-free blood pressure sensor for
application in sports medicine and
rehabilitation
 Based on the discovery of under the cuff pulse wave* a new noise-free blood pressure measuring
method was developed, which is insensitive to a patient’s movements during the measurement of
blood pressure;
 Innovation is patented in Russia and going through the patenting process in USA and Europe;
 The idea behind this method is to place a hard plate in-between the cuff and the skin in the place
where the artery passes. The pulse wave sensor is inbuilt into the plate, the presence of which leads to
the appearance of pulse wave pressure on the side pressed against the skin, which in turn is effectively
converted into an output signal;
 A model sensor of the pulse wave pressure has been constructed weighing 2,5 g and size 20х10х4 mm;
 Both the model and methods have been successfully tested at the Institute for medical and biological
problems of the Russian Academy of Sciences.
*Inventors: А.М. Romanovskaya, V.F. Romanovskiy
Plate
Artery
Pulse wave pressure sensor
Pulse wave
The spot where in blood
the pulse wave pressure appears
Cuff

7. Rehabilitron: a musculoskeletal
rehabilitation and training system
 3D vision & motion capture technology;
 Biomechanical analysis of patient’s movements;
 All deviations from the given trajectory are visualized;
 Health risks are under control with the help of biosensors.
Advantages:
Moderate price Safe Easy to Use
Mass application

8. Competitive advantages
 Multiparameter evaluation of a body’s vital signals;
 Real-time functionality, preventive approach in diagnostics
(monitoring, analysis and extrapolation);
 Use of leading biosensor methods, nanosensors.
Financing required
The funds are required for Development and clinical trials – from $1 million:
 A multi-sensor wearable platform (t-shirt/cuff) including filtration and
data correlation instruments;
 An expert diagnostic prediction service based on a trainable artificial
neural network and methods of fuzzy logic;
 Production and marketing – from $1,5 million.