The document discusses ChemSpider, a free online chemical database, and its efforts to engage the chemistry community to help build and curate its database. It describes ChemSpider's roles in hosting and exposing chemical data as well as curating submitted data. It acknowledges that while crowdsourcing engagement has been low, more collaboration across databases could help improve overall data quality. Continued growth will depend on better engaging the community to contribute to and help shape the resource.

1. ChemSpider - Does Community Engagement work to Build a Quality Online Resource for Chemists? Antony Williams ACS Denver August 30th 2011

2. What’s said on the web is true…

3. What’s said on the web is true…

5. Who is Sandy Lawson? Ask Google

7. What is the Structure of Vitamin K1?

10. I want to know about “Vincristine”

11. I want to know about “Vincristine” If all algorithms work then everything on the page is correct by default except the name!

12. Vincristine: Identifiers and Properties

13. Vincristine: Identifiers and Properties

14. Vincristine: Vendors and Sources

15. Vincristine: Patents

16. Vincristine: Articles

17. Searches: The INTERNET All ChemSpider and Internet searches are “simply algorithms” but synonym searching is based on an assertion

18. InChIs

19. Validated Names for Searching…

26. The Stereochemistry challenge. 12500 chemicals with “missed” stereo

27. NIST Webbook

28. PubChem

34. NPC Browser http://tripod.nih.gov/npc/

35. NPC Browser http://tripod.nih.gov/npc/

36. NPC Browser http://tripod.nih.gov/npc/

37. NPC Browser http://tripod.nih.gov/npc/

38. Patents

39. Patents

40. WYSIWYG compounds

41. WYSIWYG compounds

42. But Chemspider is curated right?

43. Originally 15 compounds “called” Yohimbine 54 Skeletons for Yohimbine

44. All aggegators suffer dilution!

45. What is the structure of Discodermolide?

46. How to distinguish…who’s wrong?

47. Neither is wrong

49. Curating Melting Point Data http://tinyurl.com/3e44vbx

50. Melting Point Validation Work

51. Some melting points can’t be resolved only with literature: 4-benzyltoluene

55. Proof of Concept Data Curation Sharing

62. Spectra

63. www.SpectralGame.com http://www.jcheminf.com/content/1/1/9

64. Spectral Game

65. Data Curation

66. Reversed Spectrum

67. Download, reprocess, redeposit

68. True Curation of Data

69. Batch wise validation of NMR data

70. Automated C13 Verification

71. Mixture Identified

73. ChemSpider ID 24528095 HHCOSY

74. ChemSpider ID 24528095 HSQC

76. SpectraSchool

79. ChemSpider SyntheticPages

80. ChemSpider SyntheticPages

88. RSC’s LearnChemistry:Share

92. Thank you Email: williamsa@rsc.org Twitter: ChemConnector Blog: www.chemspider.com/blog Personal Blog: www.chemconnector.com SLIDES: www.slideshare.net/AntonyWilliams