This lecture discusses how personal choices and lifestyle factors are powerful influences on health. It begins by exploring current health statistics in America, which show high rates of obesity, diabetes, heart disease and other chronic diseases. These poor health outcomes are linked to most Americans eating more calories, sugar, salt and meat compared to the past, while being less physically active. The lecture then reviews several scientific studies that demonstrate how lifestyle modifications like improved nutrition, increased exercise, weight management and avoiding tobacco can significantly reduce risks for chronic diseases and mortality. It emphasizes that lifestyle is a major determinant of health outcomes. The lecture concludes by encouraging participants to prioritize healthy living through personal goal setting and lifestyle changes.
8. “A global response to a
global problem: the epidemic
of overnutrition.” WHO
It is estimated that by 2020 2/3rds
of the global
burden of disease will be attributable to chronic
non-communicable diseases, most of them
strongly associated with diet. The nutrition
transition towards refined foods, foods of animal
origin, and increased fats plays a major role in
the current global epidemics of obesity, diabetes
and cardiovascular diseases, among other non-
communicable conditions. Sedentary lifestyles and the
use of tobacco are also significant risk factors. …….. A
concerted multi-sectoral approach, involving the use of
policy, education and trade mechanisms, is necessary
to address these matters.
12. “A global response to a
global problem: the epidemic
of overnutrition.” WHO
It is estimated that by 2020 2/3rds
of the global
burden of disease will be attributable to chronic
non-communicable diseases, most of them
strongly associated with diet. The nutrition
transition towards refined foods, foods of animal
origin, and increased fats plays a major role in
the current global epidemics of obesity, diabetes
and cardiovascular diseases, among other non-
communicable conditions. Sedentary lifestyles and the
use of tobacco are also significant risk factors. …….. A
concerted multi-sectoral approach, involving the use of
policy, education and trade mechanisms, is necessary
to address these matters.
DiabetesDiabetes
High Blood PressureHigh Blood Pressure
High CholesterolHigh Cholesterol
Heart DiseaseHeart Disease
ObesityObesity
30. Year Bee
f
Pork Total
Red
Meat
Total
Chicken
Turkey Total
Poultry
Total
Red
meat
and
Poultry
Commerci
al Fish and
Shellfish
1965 74.7 51.5 133.9 36.9 7.6 44.4 178.4 10.9
2000 67.5 50.8 120.2 77.4 17.3 94.7 214.8 15.2
2016
Prj.
55.0 49.2 105.3 91.4 16.2 107.6
213
NA
As of 9/6/15
32. 8% from Fruits
and Vegetables
8% from Fruits
and Vegetables
≈ 50% from Added
fat/oil and
processed flour
≈ 50% from Added
fat/oil and
processed flour
33. Perspective
• We eat more
– Sugar, Salt, Fat, Meat, Dairy
– 1970-2017:
• ↑ 24.5 % C/day ≈
504K/day
• We get less then ideal Physical Activity
– 18.8% of adults achieved CDC reccs on
Exercise
– 10% of adults >65 y/o
40. 1: Essential Hypertension
7: Diabetes Mellitus
15/17: Heart Disease
1: Essential Hypertension
7: Diabetes Mellitus
15/17: Heart Disease
Top 35 leading diagnosis groups at ambulatory care clinicsTop 35 leading diagnosis groups at ambulatory care clinics
41. Number and rate of discharges from short stay hospitals 2009Number and rate of discharges from short stay hospitals 2009
2: Heart Disease
8: Strokes
11: Diabetes Mellitus
17: Essential Hypertension
2: Heart Disease
8: Strokes
11: Diabetes Mellitus
17: Essential Hypertension
42. Admission Diagnosis to Nursing Homes 2009Admission Diagnosis to Nursing Homes 2009
1: Disease of Circulatory System1: Disease of Circulatory System
48. “A global response to a global
problem: the epidemic of
overnutrition.” WHO
It is estimated that by 2020 2/3rds
of the global burden
of disease will be attributable to chronic
noncommunicable diseases, most of them strongly
associated with diet. The nutrition transition towards
refined foods, foods of animal origin, and increased fats
plays a major role in the current global epidemics of
obesity, diabetes and cardiovascular diseases, among
other noncommunicable conditions. Sedentary
lifestyles and the use of tobacco are also significant
risk factors. …….. A concerted multi-sectoral approach,
involving the use of policy, education and trade
mechanisms, is necessary to address these matters.
……if…….Lifestyle is the
Problem
……if…….Lifestyle is the
Problem
What is the answer……..?What is the answer……..?
51. • What if……..
– You ate MOREfruits, vegetables,
unprocessed whole grains, nuts, seeds and beans?
– You ate LESS foods of animal origin (meat, dairy,
fish) and processed foods
– You reduced Toxic exposures
– You exercised daily
52.
53. 12 year Cohort Study
1507 men 832 Women
Ages 70-90 years
Outcomes: 10 yr all cause mortality
4 Factors: More plants, Moderate EtOH, physical exercise
and non-smoking were ass. w ↓ in ACM
50% ↓ in all-cause
and cause specific
mortality
54. “Not only do persons with better health habits
survive longer, but in such persons, disability is
postponed and compressed into fewer years
at the end of life.”
Vita, AJ et al. NEJM 1998; 338:1035-1041
55. Finnish Diabetes Prevention Trial
Total 522: 172M 350W
Av. age 55
Av. BMI 31
Randomized to standard of care or
individualized lifestyle counseling
Av. f/u 3.2 yrs
Risk of
Diabetes ↓ 58 %
(P<0.001)
N Engl J Med 2001;344:1343-50
“The reduction in the incidence of diabetes was
directly associated with changes in lifestyle”
56. Healthy living is the best revenge: findings from
the European Prospective Investigation Into
Cancer and Nutrition-Potsdam study 2009
• 23,153 participants (35 to 65yr) for about 8 years
• Rates of type 2 diabetes mellitus, myocardial
infarction, stroke, and cancer
• 4 Variables:
– Never smoking
– BMI<30
– 3.5 h/wk or more of physical activity
– healthy dietary principles (high intake of fruits,
vegetables, and whole-grain bread and low meat
consumption).
If you had all 4 factors at baseline you had
• 78% lower risk of developing a chronic disease
•
• 93% lower risk of diabetes
•81% lower risk of myocardial infarction
•50% lower risk of stroke, and
•36% lower risk of cancer
If you had all 4 factors at baseline you had
• 78% lower risk of developing a chronic disease
•
• 93% lower risk of diabetes
•81% lower risk of myocardial infarction
•50% lower risk of stroke, and
•36% lower risk of cancer
Sign Me Up!Sign Me Up!
57. What we Know
Health Comes from
Healthy Living
Health Comes from
Healthy Living
58. We know
• Health Comes from Healthy Living
–MORE Color
–MORE Movement
– Reduce/Eliminate Toxins
– Spiritual/Emotional Well-Being
70. Exercise and Physical Health
• Reduces risk of
– Heart Disease ≈ 40%
– Obesity: ≈ 30-100%
– Stroke ≈ 50%
– Type 2 Diabetes ≈ 50%
– Hypertension ≈ 50%
– Disability delayed ≈15 years
– Colon Cancer ≈ 25-40%
– Breast Cancer ≈ 20%-44%
– Osteoporosis ≈ 20+%
• As many as 250,000 deaths per year in the United States
areattributable to a lack of regular physical activity
71. Exercise and Mental Health
• Regular Exercise:
– Reduces risk/severity of:
• Depression
• Anxiety
• ADD/ADHD
• Alzheimers Dementia
– Improves:
• Mental Clarity, test scores, focus
72. Exercise and Emotional Health
• Regular Exercise:
– Increases Self Confidence
– Teaches skills to manage adversity
– Enhances Self Esteem
– Develops Discipline
– Encourages Goal setting and self awareness
73. Exercise means pink spandex, going to a
gym, sweating with a bunch of people I
don’t even know or like!
74.
75. Categories
• Leisure time Exercise: organized sports,
running, gym activities, rehabilitation etc.
• Lifestyle Exercise: activity incorporated into our
daily pattern of life
– eg: parking in the distant portion of the parking lot rather then the first
bumper, taking the stairs instead of the elevator etc.
76. Present Recommendations
• Cardiovascular:
– 150 minutes of moderate-intensity exercise per
week.
– 30-60 minutes of moderate-intensity exercise (five
days per week) or 20-60 minutes of vigorous-
intensity exercise (three days per week).
77. Present Recommendations
• Resistance Training:
– 2-3 days per week
– All major muscle groups
– 2-4 sets of each exercise
– 48 hours in between sessions
http://www.acsm.org/about-acsm/media-room/news-releases/2011/08/01/acsm-issues-new-
recommendations-on-quantity-and-quality-of-exercise
79. All Kinds
• People
• Programs
• Locations
• Products: Pedometers, Accelerometers etc
80. Intensity of Exercise
Maximal Heart Rate:
220-Age or 206.9-(0.67x age)
Heart Rate Reserve (HRR):
Max. HR- Resting HR = HRR
Target HR=HRR x % intensity + HR @ rest
Maximal Heart Rate:
220-Age or 206.9-(0.67x age)
Heart Rate Reserve (HRR):
Max. HR- Resting HR = HRR
Target HR=HRR x % intensity + HR @ rest
Talk Test:
-Easy: Can Talk and Sing
-Moderate: Can Talk but not sing
-Intense: Can’t talk or sing
Talk Test:
-Easy: Can Talk and Sing
-Moderate: Can Talk but not sing
-Intense: Can’t talk or sing
81. Nutrition
• Up to 50% of Americans are on a Diet
DIEtDIEt
LifestyleLifestyle
82. Nutrition
• Health Promoting Nutrition:
• Majority of Calories derived from Plant-Based
Sources
• Limited Calories from Refined Foods and
Foods of Animal Origins
86. Toxins
• Get em’ out
• Get help if you need it
• You can do it
• You deserve it
87. Basics
• Physical Activity:
– Achieve 150 min of aerobic exercise and 2
sessions of strength training per week
• Nutrition:
– Eat a high nutrient density program
– Limit/moderate lean meats, limit refined foods,
fat, sodium and cholesterol
• Eliminate Smoking and Limit Alcohol
Consumption
92. Break Out: 4 minutes
• Set YOURSELF a SMART Goal for 1 Lifestyle
Measure and share it with your neighbor!
• Specific
• Measureable
• Achievable
• Realistic
• Timely
Exercise
Nutrition
Toxins
Sleep
Emotional
Poise(Stress)
Exercise
Nutrition
Toxins
Sleep
Emotional
Poise(Stress)
93. Conclusion
• Personal Choices are powerful Medicine
• Assess YOUR Health Today
• Identify your health goals
• Develop a support team
• Take charge of your health today!
-- Bull World Health Organ. 2002;80(12):952-8. Epub 2003 Jan 23. Chopra M et al
Approx. 1,300,000 new cases per year
www.cdc.gov/.../mmwrhtml/ figures/m846qsf.gif
www.ncbi.nlm.nih.gov/ bookshelf/picrender.fcgi..
http://www.ctahr.hawaii.edu/CS/blogs/sustainable_agriculture/cdc_logo(2).jpg
Modifiable behavioral risk factors are leading causes of mortality in the United States. (JAMA, 2000 Mokdad et al. CDC)
www.cdc.gov/cancer/ breast/statistics/
http://www.cdc.gov/cancer/Prostate/publications/decisionguide/
Fox, Caroline. Et al. Trends in the Incidence of Type 2 Diabetes Mellitus: Circulation 2006:113;2914-2918.
http://health.ucsd.edu/news/images/DPP1.jpg
In 2005-2008 11% of adults 20 years of age or older had diabetes. In 2005-2008 the percentage of adults with dm increased with age from 4% of persons 20-44 to 27% of adults 65 years of age or older
http://meps.ahrq.gov/mepsweb/
Medical Expenditure Panel survey
http://www.heart.org/idc/groups/heart-public/@wcm/@sop/@smd/documents/downloadable/ucm_319587.pdf
The prevalence of hypertension (defined as high blood pressure or taking antihypertensive medication) increases with age. In 2005–2008, 33%–34% of men and women 45–54 years of age had hypertension, compared with 67% of men and 80% of women 75 years of age and over (Table 67).
http://sas-origin.onstreammedia.com/origin/gallupinc/GallupSpaces/Production/Cms/POLL/yxirhsg6pe-ttjvtlo_uuq.gif
These findings are based on 24 months of Gallup-Healthways Well-Being Index daily tracking data from 2009 through 2010, encompassing surveys with more than 650,000 U.S. adults, aged 18 and older. The resulting sample sizes for every age from 18 through 90 -- ranging from roughly 1,500 to 18,000 cases -- allow for age-specific analysis of the data.
--http://www.ers.usda.gov/briefing/consumption/Effects.htm
now 129.2
--IOM rec on Na: AI 1.5g/d UL 2.3g/d
--http://www.cspinet.org/
--http://www.ama-assn.org/ama/pub/category/16461.html
-- http://www.iom.edu/?id=18495&redirect=0
-- Dr. Heikki Karppanen of the University of Helsinki and Dr. Eero Mervaala of the University of Kuopio report that an average 30-35 % reduction in salt intake during 30 years in Finland was associated with a dramatic 75 % to 80 % decrease in both stroke and coronary heart disease mortality in the population under 65 years. During the same period the life expectancy of both male and female Finns increased by 6 to 7 years.The most powerful explaining factor for the favorable changes was the more than 10 mmHg (&quot;point&quot;) decrease in the average blood pressure of the population. A marked decrease in the average cholesterol levels of the population also remarkably contributed to the decrease of heart diseases. The extensive use of drugs contributed less than 10 % of the observed decreases in blood pressure, cholesterol, and cardiovascular diseases.
--http://www.iom.edu/Object.File/Master/20/004/0.pdf
http://fnic.nal.usda.gov/nal_display/index.php?info_center=4&tax_level=3&tax_subject=256&topic_id=1342&level3_id=5140
2012 Data total up to 603 lb of dairy per person per year
http://xe9.xanga.com/05df647715d32268783403/m214397325.jpg
http://www.ers.usda.gov/Publications/EIB33/EIB33_Reportsummary.pdf
Daily calories per capita per food group
2569:
Agouti = defect in alpha melanocyte stimulating hormone a secondary molecule increased by increasing leptin levels.
Early nutrition can influence DNA methylation because mammalian one-carbon metabolism, which ultimately provides the methyl groups for all biological methylation reactions, is highly dependent on dietary methyl donors and cofactors.[21] For example, dietary methionine and choline are major sources of one-carbon units, and folic acid, vitamin B12, and pyridoxal phosphate are critical cofactors in methyl metabolism. The genome of the preimplantation mammalian embryo undergoes extensive demethylation, and appropriate patterns of cytosine methylation are re-established after implantation.[4] These DNA methylation patterns must then be maintained over many rounds of rapid cellular proliferation during fetal and early postnatal development. Availability of dietary methyl donors and cofactors during critical ontogenic periods therefore might influence DNA methylation patterns. [10 and 16] Hence, early methyl donor malnutrition (i.e., overnutrition or undernutrition) could effectively lead to premature “epigenetic aging,” [22] thereby contributing to an enhanced susceptibility to chronic disease in later life.
Vitamin B12, choline, Vitamin B6
Gila Reservation Arizona
Maycoba, Mexico
Nauru
World’s smallest island country just 8.s sq miles
95% are overweight/obese and 50% have diabetes
Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project.
--compression-of-morbidity hypothesis predicts that the age at the time of initial disability will increase more than the gain in longevity, resulting in fewer years of disability and a lower level of cumulative lifetime disability.
--FDDP (N Engl J Med 2001;344:1343-50.)
150 min/wk of exercise, Low fat, low cholesterol plant based diet, high fiber foods
(Journal of the American Medical AssociationJAMA: 2000, Vol. 283. No. 22, pp. 2961-2967)
http://www.news.harvard.edu/gazette/1999/10.21/diabetes.html
http://www.reuters.com/article/healthNews/idUSTRE53E71N20090415?feedType=RSS&feedName=healthNews
http://www.nature.com/bjc/index.html
http://www.ncbi.nlm.nih.gov/pubmed/18599492?ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
In fact in studies regular exercise has been proven as effective as antidepressants and anxiolytics in controlling mild-moderate depression
Must be high enough to actually see gains
Studies demonstrate must at least be at 40% of max to see increases in cardiovascular endurance…..
Moderate intensity is 64-76% of HR max
http://www.mehn.org.au/images/stories/mehn/Ex_RPE_Scale.jpg
http://lh4.ggpht.com/_hbZ_aIisSu8/Sj4dT9_2kPI/AAAAAAAAAbo/r-Hmqox_oJs/Table_thumb.jpg
http://www.cvtoolbox.com/cvtoolbox1/exercise/supports/Exercise_METS.gif
--http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm
--Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ. 297: 319–328.
--The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT,2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives.
--
--http://www.nhlbi.nih.gov/new/press/nov30a99.htm
--Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
--http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm
--Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ. 297: 319–328.
--The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT,2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives.
--
--http://www.nhlbi.nih.gov/new/press/nov30a99.htm
--Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
--http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm
--Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ. 297: 319–328.
--The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT,2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives.
--
--http://www.nhlbi.nih.gov/new/press/nov30a99.htm
--Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
--http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf
--http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm
--Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ. 297: 319–328.
--The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT,2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives.
--
--http://www.nhlbi.nih.gov/new/press/nov30a99.htm
--Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
SpecificWell definedClear to anyone that has a basic knowledge of the project
MeasurableKnow if the goal is obtainable and how far away completion is
Know when it has been achievedAgreed UponAgreement with all the stakeholders what the goals should be
RealisticWithin the availability of resources, knowledge and time
Time BasedEnough time to achieve the goalNot too much time, which can affect project performance