3. About Diabetes
20.8 million Americans have diabetes (7%
of the population).
54 million Americans have prediabetes.
Diabetes is the seventh leading cause of
death from disease in the United States.
4. Continuation…
People with diabetes either do not
produce insulin or cannot effectively use
it.
Diabetes is characterized by
hyperglycemia.
5. Type 1 Diabetes Mellitus
Accounts for 5% to 10% of cases
Previously called insulin-dependent or juvenile-
onset diabetes
Severe, unstable form
Caused by autoimmune destruction of
pancreatic cells
Can occur at any age
Requires exogenous insulin
6. Type 2 Diabetes Mellitus
Accounts for 90% to 95% of cases
Previously called adult-onset or
non–insulin-dependent diabetes
Initial onset usually after age 40 years
Now being diagnosed in children
Strong genetic link
Prevalent in older, obese people
Caused by insulin resistance or defect
Usually treated with diet, exercise
7. Risk Factors for Type 2 Diabetes
Mellitus
Family history of diabetes
Age 45 years or older
Overweight
Not physically active
Race/ethnicity (African American, Hispanic American, Native
American, Asian American, Pacific Islander)
History of gestational diabetes
Woman who has delivered infant weighing more than 9 pounds
Identified impaired glucose tolerance
8. Gestational Diabetes
Temporary form of disease occurring in
pregnancy
Presents complications for mother and
fetus/infant
Must be carefully monitored and
controlled
9. Symptoms of Diabetes
Initial signs
Increased thirst
Increased urination
Increased hunger
Unusual weight loss (type 1)
Unusual weight gain (type 2)
11. Metabolic Patterns of Diabetes
Diabetes is especially related to metabolism of carbohydrate
and fat.
It is important to control blood glucose within normal levels
of 70 to 110 mg/dl.
If diabetes is uncontrolled and insulin is lacking:
Glucose cannot enter the cells and builds up in the blood.
Fat tissue breaks down.
Protein breaks down, causing weight loss and nitrogen
loss.
12. Continuation…
Three basic stages of normal glucose
metabolism:
Initial interchange with glycogen and
reduction to smaller central compound
Joining with fat and protein
Common energy production
13. Normal blood glucose balance
Sources of glucose include glycogen, carbohydrate, fat, and
protein
Uses:
Burned for energy needs
Changed to glycogen
Stimulate lipogenesis
Inhibit tissue fat breakdown
Promote amino acid uptake
16. Insulin
Controls blood sugar
Helps transport glucose into cells
Helps change glucose to glycogen and store it in liver,
muscles
Stimulates changes of glucose to fat for storage as body fat
Inhibits breakdown of tissue fat and protein
Promotes uptake of amino acids
Influences burning of glucose for energy
17. Glucagon
Acts in a manner opposite to insulin
Breaks down stored glycogen and
fat
Raises blood glucose as needed to
protect brain during sleep or fasting
18. Long-Term Complications of Diabetes
Retinopathy (diseases of retina which results in impairment or loss of vision)
Nephropathy (kidney disease caused by diabetes)
Neuropathy (damage or dysfunction of one or more nerves that may lead
to muscle pain)
Heart disease
Dyslipidemia(elevated LDL or bad cholesterol) makes up most of body's
cholesterol. High levels of low density lipoprotein (LDL) raise risk for heart
disease and stroke.
Hypertension: condition characterized by high blood pressure.
19. Key concepts in management of
Diabetes Mellitus
A consistent, sound diet is the keystone of diabetes
care and control.
Daily self-care skills enable a person with diabetes to
remain healthy and reduce risks for complications.
Blood glucose monitoring is a critical practice for
blood glucose control.
A personalized care plan balancing food intake,
exercise, and insulin regulation is essential to
successful diabetes management.
20. COMPONENTS OF DIABETES MELLITUS
TREATMENT
The major components of the treatment of
diabetes are:
Diet and Exercise
Oral hypoglycemic therapy/oral anti diabetic
agents
Insulin Therapy
21. Diet
Diet is a basic part of management in every case.
Dietary treatment should aim at:
• Ensuring weight control
• Providing nutritional requirements
• Allowing good glycaemia control with blood glucose
levels as close to normal as possible
23. Recommended dietary guidelines for
people with diabetes:
The following principles are recommended as dietary guidelines for
people with diabetes:
Dietary fat should provide 25-35% of total intake of calories but
saturated fat intake should not exceed 10% of total energy.
Cholesterol consumption should be restricted and limited to 300 mg
or less daily
Protein intake can range between 10-15% total energy (0.8-1 g/kg
of desirable body weight).
Excessive salt intake is to be avoided. It should be particularly
restricted in people with hypertension and those with nephropathy.
24. Exercise
The following are some of the advantages that comes with
regular exercising;
Physical activity promotes weight reduction and improves
insulin sensitivity, thus lowering blood glucose levels.
Exercising also helps to provide physical fitness and
carbohydrate metabolism.
It also helps reduce the risk factors for cardiovascular
diseases.
Exercise also helps lower cardiac work and blood pressure.
25. Considerations during exercise
Use proper footwear (shoes) during exercise
Avoid exercise in extreme temperature
Inspect your feet daily.
Avoid exercise in periods of poor metabolic control
example when sick or not feeling well.
Don’t exercise on an empty or full stomach.
26. Oral hypoglycemic therapy/oral anti
diabetic agents.
There are three functional types of Oral anti diabetic agents and
these are;
Those that target insulin secretion; example sulphonylureas
which increase insulin secretion by pancreatic beta cells.
Those that target insulin resistance; for example Biguanides
which inhibits glucose production by the liver and thus does not
produce weight gain, useful in obese clients.
Those that target glucose absorption from the intestine;
example we have Alpha glucosidase inhibitors which Inhibit
carbohydrate absorption in the small intestine.
27. INSULIN THERAPY
This is especially used in the
treatment of type 1 diabetes and in
acute cases of type 2 diabetes
mellitus.
28.
29.
30. ASSIGNMENT/COURSE WORK
Read and make brief notes on the following Blood Sugar Test Methods.
Fasting blood sugar test
Post prandial blood sugar test
HBAIC test
Instructions:
Use font size of 12 and font style of New Times Roman.
Please make sure your work is Justified
Use line spacing of 1.5
Use resources from the University Library and or the Internet