Presented in Upgraded Life Festival 31.5.2016 by Lauri Sippola, NETMEDI. http://www.upgradedlifefestival.com/

1. Netmedi Oy / @kaikuhealth / @laurisippola

2. Confidential / Netmedi Oy
2013
First clinical research project with HUCH
1
in the Nordics
10k
patients

3. Agenda
1. Kaiku Health
2. Patient reported outcomes
3. Future of data driven care

4. K L I N I K A A R A U
K L I N I K Z Ü R I C HK L I N I K M Ä N N E D O R F
K L I N I K L A U S A N N E
S O M E O F O U R
R E F E R E N C E S

5. Kaiku is a web-platform that automates symptom follow-up and
data capture during and after cancer treatment.
The patient stays connected – anywhere, anytime, any device.

6. Patient reports structured feedback
on adverse events and quality of life.

7. Kaiku can give information
to the patient.
Kaiku alerts automatically the
medical staff according to the
pre-programed parameters.

8. 95% 75% x10
Positive impact on
treatment experience by
patients
Reduction in calls Real-world data

9. Data from 2015
0
20000
40000
60000
80000
100000
120000
140000
160000
180000
0
500
1000
1500
2000
2500
3000
3500
4000
2013-Q1
2013-Q2
2013-Q3
2013-Q4
2014-Q1
2014-Q2
2014-Q3
2014-Q4
2015-Q1
2015-Q2
2015-Q3
2015-Q4
Numberofpatients
Patients Data points
3460 patients
11% average
monthly growth
167 110 data points
356 % growth during
in 12 months
Numberofdatapoints
15 25+ 89%
Centers Adverse event follow-up
templates for different
cancer and therapy
combinations
Patient compliance
(registered / invited)

10. Agenda
1. Kaiku Health
2. Patient reported outcomes
3. Future of data driven care

11. Why is data about patient’s experience
significant for better healthcare?
Patient-reported outcomes (PRO)
= PRO is any report of the status of a patient's health
condition that comes directly from the patient, without
interpretation of the patient's response by a clinician or
anyone else. (US-FDA)

12. Why are PROs important?
"After all, only the patient himself is aware of his
wellbeing and can report on possible warning signs,
while the doctor can use these reports to evaluate the
progress of the disease and treatments on the basis of
their medical expertise."
Confidential / Netmedi Oy

13. Basch et al: Symptom Monitoring With Patient-Reported Outcomes
During Routine Cancer Treatment: A Randomized
Controlled Trial. Clin Oncol 34:557-565, 2016
Web-based symptom reporting with automated clinician e-mail alerts resulted in
better quality of life, fewer emergency room visits and longer duration of
treatment as well as better quality-adjusted survival for patients. (N = 766)

14. Agenda
1. Kaiku Health
2. Patient reported outcomes
3. Future of data driven care

15. Patient is connected with Kaiku®
Health.
Kaiku® Health captures
specific symptom and
quality of life data.
Kaiku® Health automatically
gives routine instructions to
frequently asked questions.
Kaiku® Health filters the
patients.
Kaiku® Health notifies the
medical staff according to pre-
defined
parameters.
Kaiku® creates analytics:
• Individual patient
• Populations
• Clinical trial support

16. Case 1: Monitoring outcomes of immunotherapy
and complex combinations
Prevent
Anticipate
Detect
Treat
Monitor
Source: Annals of Oncology: 559-574, 2016

17. Case 2: Forecasting risk
25%
Risk of recurrence

18. Improve
quality of
life
Monitor Forecast
Future:

19. Enabling data-driven care and personalized
care.
Kaiku is the patient’s individual guide through cancer treatment and
recovery, and a real-time dashboard that allows the caregiver to
improve outcome-driven care.
Confidential / Netmedi Oy

20. Thank you.
Confidential / Netmedi Oy
Lauri Sippola
CEO and Co-founder
+358 40 744 7481
lauri.sippola@netmedi.fi
@laurisippola
www.kaikuhealth.com