The Interstitial Cystitis Association (ICA), a non-profit health association, hosted a Patient Forum in Atlanta on Sunday, August 23, 2009. This CDC-funded event offered healthcare providers, patients and caregivers a chance to meet with leaders in the field to learn more about interstitial cystitis - a severely painful and chronic bladder condition affecting an estimated 3 million women and 1 million men in the United States. Speakers included Dr. Jeffrey Proctor, Dr. Anna Kelly and Susan Bilheimer.

1. A to Z on IC Interstitial Cystitis Association August 23, 2009 1:00 PM ET Conquering IC. Changing Lives . The goal of the forum is to offer patients an opportunity to learn more about IC treatments. The content presented reflects the opinions of individual speakers. 1

6. A to Z on IC TREATMENTS AND RESEARCH Jeffrey G. Proctor, M.D. Georgia Urology Cartersville, GA

15. Adapted with permission from Evans RJ. Rev Urol . 2002;4(suppl 1):S16-S20. Proposed Pathogeneis A Continuous Cycle Bladder Insult Origin of Bladder Insult (eg, Bacterial Cystitis, Childbirth, Pelvic Surgery, or Urologic Instrumentation) More Injury Mast Cell Activation and Histamine Release Activation of C-Fibers and Release of Substance P Solutes Leak Into Interstitium Bladder Urothelium Dysfunction

30. Utilizing Multimodal Therapy in the Treatment of IC 1 Adapted with permission from Evans RJ. Rev Urol . 2002;4(suppl 1):S16-S20. 1. Evans RJ. Rev Urol . 2002;4(suppl 1):S16-S20. 2. Chiang G et al. J Urol . 2000;164:2119-2125. 3. Chiang G et al. In: Bladder Disease, Part B: Research Concepts and Clinical Applications . Kluwer Academic/Plenum Publishers; 2003:713-729. Bladder Insult Origin of Bladder Insult (eg, Bacterial Cystitis, Childbirth, Pelvic Surgery, or Urologic Instrumentation) More Injury Mast Cell Activation and Histamine Release Activation of C-Fibers and Release of Substance P Solutes Leak Into Interstitium Bladder Urothelium Dysfunction Hydroxyzine, ELMIRON ®2,3 Amitriptyline ELMIRON ® (pentosan polysulfate sodium)

41. RESEARCH

50. Research Defective Tamm-Horsfall Protein in Patients With Interstitial Cystitis Cl Parsons, P Stein, P Zupkas, M Chenoweth, S Argade, JG Proctor, A Dutta and N Trotter. J. Urology 2007; 178: 2667.

57. FIG. 2. Representative N-terminal residue results of MALDI-TOF MS analysis of intact glycosylation chains of THP from 10 controls ( A ) and 10 patients with IC/painful bladder syndrome ( B ). All 10 patients and all 10 controls showed same basic patterns. Patients had preponderance of lower molecular weight chains and little of heavier chains containing tri-antennary and tetra-antennary terminal sialic acid residues, whereas controls had preponderance of heavy chains, representing primarily tri-antennary and tetra-antennary terminal sialic acid residues

93. Cartesian Model vs. Eastern Thought

98. Yang and Yin Yang Light Male Outside Back Hot Hollow Heaven Yin Dark Female Inside Front Cold Solid Earth

101. Directed Electron Flow

102. Meridian Pathway

109. Acupuncture and Electroacupuncture in the Treatment of Interstitial Cystitis