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TAT IN RISK
DETECTION AND
PREVENTION OF
CARDIOVASCULAR
DISEASE
TELOMERE LENGTH
INDEPENDENT RISK
FACTOR FOR CVD
TELOMERE MEASUREMENT CAN IDENTIFY HIGH RISK INDIVIDUALS WITH SHORT TELOMERES
TAT ( TELOMERE ANALYSIS TEST) USED TO COMPLEMENT TRADITIONAL CARDIOVASCULAR
TESTS IN ORDER TO PROVIDE MORE COMPREHENSIVE ANALYSIS AND  IDENTIFY THE RISKS
OF DEVELOPING CARDIOVASCULAR PROBLEMS AT AN EARLIER STAGE
REDUCED TELOMERE LENGTHS ARE FOUND IN PATIENTS
WITH CARDIOVASCULAR RISK FACTORS SUCH AS:
ATHEROSCLEROSIS
HYPERTENSION
OBESITY
DIABETES (ESPECIALLY TYPE 2)
SMOKING
PHYSICAL INACTIVITY
STRESS
CHRONIC INFECTIONS
A positive effect on telomere length is found with increased
physical activity, statin treatment, and higher blood levels of
omega­3 fatty acids
Statins may extend lives by not only lowering cholesterol levels but also protecting
against telomere shortening, thus reducing the risk of cardiovascular disease and
other age­associated diseases
A) All individuals
B) Individuals on
pravastatin
treatment
(grey) or placebo
(orange)
 

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