Doctors know it is not an uncommon situation that patients using proton-pump inhibitors have problems with low iron and even iron deficiency. Non-heme iron absorption is dependent on an acidic stomach in order for the iron to be released and eventually absorbed. Achlorhydria does not concern heme iron. Heme iron is taken up efficiently as a whole structure leaving no free iron ions to irritate. Uptake is not dependent on stomach acid.

1. WHAT IS ACHLORHYDRIA?
Achlorhydria refers to states where the
produc@on of hydrochloric acid in gastric
secre@ons of the stomach and other diges@ve
organs is absent or low, respec@vely.
Wikipedia

2. WHAT ARE PROTON-PUMP
INHIBITORS?
Proton-pump inhibitors are a group
of drugs whose main ac@on is a pronounced and
long-las@ng reduc@on of gastric acid produc@on.
Wikipedia

3. WHAT IS OMEPRAZOLE?
Omeprazole, sold under many brand names such
as Prilosec and Losec among others, is a
medica@on used in the treatment
of gastroesophageal reflux disease, pep@c ulcer
disease, and Zollinger–Ellison syndrome.
Omeprazole is a proton pump inhibitor and as
such blocks the release of stomach acid.
Wikipedia

4. OMEPRAZOLE STOPS NON-HEME
IRON ABSORPTION
Doctors know it is not an uncommon situa@on
that pa@ents using proton-pump inhibitors have
problems with low iron and even iron deficiency.

5. UPTAKE DEPENDENT ON
STOMACH ACID
Non-heme iron absorp@on is dependent on an
acidic stomach in order for the iron to be
released and eventually absorbed.

6. NO UPTAKE OF NON-HEME IRON
Uptake of non-heme iron does not happen in a
achlorhydric situa@on where the pa@ent is using
a proton-pump inhibitor.
Uptake of non-heme iron does not happen in a
achlorhydric situa@on where the pa@ent is using
a proton-pump inhibitor.

7. DEFICIENCY EVEN WHEN
SUPPLEMENTING
As a result many pa@ents have low iron or even
iron deficiency even as they supplement with the
regular non-heme iron prepara@ons.

8. HEME IRON IS ALWAYS TAKEN UP
Achlorhydria does not concern heme iron.
Heme iron is taken up efficiently as a whole
structure leaving no free iron ions to irritate.
Uptake is not dependent on stomach acid.

9. www.op@fer.interna@onal www.hemeiron.com YouTube
Swedish Op@Fer® heme iron supplements
are safe, efficient and very well tolerated