Muscles Part 1 Prepare by Dr. Mohammed Alruby Histology of muscles Physiology of muscles Muscles development Orofacial muscles - Facial muscles - Jaw muscles - Portal muscles Methods of studying muscles Muscle changes during growth Muscle function and facial development Histology of muscles The structural and functional unit of the muscles is the muscle fiber Muscle fiber: elongated cylinder measure about 10 to 80 microns in thickness and from 1 to 15cm in length = Each muscle fiber contains an acidophilic granular cytoplasm (sarcoplasm) that rich in: Glycogen, mitochondria, Golgi apparatus, protein (actin, myosin, tropomyosin), Large number of myofibrils (sarcostyles) which responsible for muscle contraction = the muscle fiber is covered by thick membrane called (sarcolemma) and surrounded by CT called (endomysium) = the muscle fibers are coalescing together to form bundles; each bundles are covered by C T septa called perimysium = the muscle bundles are coalescing together to the whole muscle which is covered by CT fascia called epimysium, these CT contain: blood vessel, lymph vessel, and nerves, that firmly attach the muscle bundles to each other and attach the whole muscle to its tendon = the myofibrils (sarcostyles)are the contractile units of the muscle, in skeletal muscle they are transversely striated due to presence of dark and light bands The dark bands are formed of thick myosin filaments rich in Ca, the light bands are formed of thin actine filaments rich in water, there is a pale line in at the center of dark band called (Henesen’s disk), There is dark line at the center of light bands called (Krauses membrane) or Z line The distance between the two lines called (sarcomere) which is a contraction unit of the muscle. During the muscle contraction there the Sarcomere is shortened due to sliding of the light bands over the dark bans. The energy required for contraction is derived from transformation of ATP ------ ADP Physiology of muscles: Man has 639 muscles, composed of 6 billion muscle fibers, each fiber has 1000 fibrils, which means that there are 6000 billion fibrils at work at one of time or another. Elasticity: muscle can be stretched behind its original length and return to the original shape after relaxation (normal muscle can be elongated about 6/10 of its length Contractility: it is the ability of muscle to shorten its length under nerve impulse, this contraction is stimulated by acetyl choline, glycogen is partially oxidized to provides energy and lactic acid that carried away by blood stream Excessive accumulation of lactic acid can produce fatigue Isometric contraction: (stretching): the muscle is simply resisting the external forces without actual shortening Isotonic contraction: there is an actual shortening of the muscle, the strength of isometric contraction is much greater than that of isotonic contraction as the stre
Muscles Part 1 Prepare by Dr. Mohammed Alruby Histology of muscles Physiology of muscles Muscles development Orofacial muscles - Facial muscles - Jaw muscles - Portal muscles Methods of studying muscles Muscle changes during growth Muscle function and facial development Histology of muscles The structural and functional unit of the muscles is the muscle fiber Muscle fiber: elongated cylinder measure about 10 to 80 microns in thickness and from 1 to 15cm in length = Each muscle fiber contains an acidophilic granular cytoplasm (sarcoplasm) that rich in: Glycogen, mitochondria, Golgi apparatus, protein (actin, myosin, tropomyosin), Large number of myofibrils (sarcostyles) which responsible for muscle contraction = the muscle fiber is covered by thick membrane called (sarcolemma) and surrounded by CT called (endomysium) = the muscle fibers are coalescing together to form bundles; each bundles are covered by C T septa called perimysium = the muscle bundles are coalescing together to the whole muscle which is covered by CT fascia called epimysium, these CT contain: blood vessel, lymph vessel, and nerves, that firmly attach the muscle bundles to each other and attach the whole muscle to its tendon = the myofibrils (sarcostyles)are the contractile units of the muscle, in skeletal muscle they are transversely striated due to presence of dark and light bands The dark bands are formed of thick myosin filaments rich in Ca, the light bands are formed of thin actine filaments rich in water, there is a pale line in at the center of dark band called (Henesen’s disk), There is dark line at the center of light bands called (Krauses membrane) or Z line The distance between the two lines called (sarcomere) which is a contraction unit of the muscle. During the muscle contraction there the Sarcomere is shortened due to sliding of the light bands over the dark bans. The energy required for contraction is derived from transformation of ATP ------ ADP Physiology of muscles: Man has 639 muscles, composed of 6 billion muscle fibers, each fiber has 1000 fibrils, which means that there are 6000 billion fibrils at work at one of time or another. Elasticity: muscle can be stretched behind its original length and return to the original shape after relaxation (normal muscle can be elongated about 6/10 of its length Contractility: it is the ability of muscle to shorten its length under nerve impulse, this contraction is stimulated by acetyl choline, glycogen is partially oxidized to provides energy and lactic acid that carried away by blood stream Excessive accumulation of lactic acid can produce fatigue Isometric contraction: (stretching): the muscle is simply resisting the external forces without actual shortening Isotonic contraction: there is an actual shortening of the muscle, the strength of isometric contraction is much greater than that of isotonic contraction as the stre