Pharmacist Model Question Based on NPC Syllabus By Nabin Bist

1. Pharmacist Model Qesution by Nabin Bist
​ ​ Nepal Pharmacy Council
License Exam model set
Pharmacist
1.Chief chemical constituents of atropa belladonna is
a. Atropine. b.Pilocarpine
c.​Hyoscine​. d.None
2.Essential oil is the other name for
a.​Volatile​ ​oil​. ​ b.Fixed oil
c.Mineral oil. d.None
3.The main compound of ephedra herb is the analogue of the synthetic molecule ….
a.​Amphetamine​. b.Ketamine
c.Phencyclidine. d.Ethyl morphine
4.Which of the following drug was inspired by nature ?
a.Morphine. ​ ​b.Salbutamol
c.Citalopram. d.Erythromycin
5.Find out the pair of plant with the similar therapeutic value
a.cinnamon and castor. b.Nicotine and Rauwolfia
c.Ipecac and Holarrhena. d.Digitalis and Withania
6.Methylation of one of the (OH-group) in morphine structure yield
a.Heroin b.pethidine
c.papaverine ​d.codeine
7.What crucial feature of a penicillin is involved in its mechanism of action?
a.Carboxylic acid ​ ​ b.B-Lactam ring
c.Acyl side chain d.Thiazolidine ring
8.Anthraquinone can be obtained from
a.Rhubarb ​ ​b.Senna
c.Digitalis d.All
9.Steam distillation is use for isolate
a.alkaloids b.tannin
c.volatile oil d.saponin

2. Pharmacist Model Qesution by Nabin Bist
10.Which one is an alkaloid?
a.Ephedrine​ b.Digitoxin
c.Ergosterol d.prostaglandins
11.Sweat flag is the synonymous of plant
a.Digitalis ​ ​b.Acorus
c.Belladonna d.Asuro
12.Medicinal plant should be dried at
a.Sun light b.Hot air oven
c.Shade drying d.Direct Heat
13.Rauwolfia serpentina which part is generally used for medicinal purpose
a.Root​ ​ b.Rhizome
c.Leaf d.flowers
14.Jatamansi is used for treatment of
a.Fever ​ ​b.Epilepsy
c.Cough d.All
15.Fishing and molisch's test are positive with
a.Guar gum b.starch
c.gum acacia​ d.Alkaloid
16.Which of the following is natural pesticide
a.Pyrethrum​ b.Garlic
c.Bojho d.Zinger
17.Which of the following having high molecular weight
a.Resin b.Tannins
c.Volatile oil d.Fixed oil
18.Mayer’s reagent contains:
a. Potassium bismuth iodide
b​. Potassium mercuric iodide solution
c. Saturated solution of picric acid
d. Aqueous iodide solution
19.Which of the following plant is used as laxative?
a​. ​Rhubarb b. Rubus
c.Rauwolfia d.Rhododendron

3. Pharmacist Model Qesution by Nabin Bist
20.Which of the following plant is used as anti-malarial?
a. ​Artemesia​ ​ b.Ashwagandha
c.Tulsi d.Rhododendron
21.which concentration, phenol act as preservative
a​. 0.2 – 0.5 b. 0.5 – 0.8
c. 0.05 – 0.1 d.None
22.Which of the following co – solvents are used to increase the solubility of a drug
a. Ethanol b.Sorbitol
c. Glycerin d. ​All the above
23.Sulfonamides are metabolised by humans principally by
a.acetylation b.deamination
c.oxidation d.conjugation
24.In which drug is the pharmacological activity associated with a specific optical
isomer?
a. ​adrenaline b.aspirin
c. phenobarbitone d.acetylcholine
25.RF value is always
a.1 b.2
c.3 ​ ​d.less than 1
26.Which of the following techniques would be most useful to identify and quantify the
presence of known impurity in a drug substance ?
a.NMR b.MS
c.IR ​ ​d.HPLC
27.Which one gas can not be used as carrier gas in gas chromatography ?
A.hydrogen b.nitrogen
c.helium ​d.oxygen
28.The ultraviolet region of the spectrum used in drug analysis
a.50-200 nm b.​200-400 nm
c.200-700 nm d.400-600 nm
29.Microbial assay is done for
a.vit A ​b.Vit B group
c.Vit C d.All
30.Best reagent to detect amino acid in TLC is
a.ninhydrin b.iodine
c.potassium permanganate d.copper sulphate
31.Certification of laboratory for its reliability is called

4. Pharmacist Model Qesution by Nabin Bist
a.GLP audit b.​performance evaluation
c.Accreditation d.proficiency testing
32.Which is not stationary phase in adsorption thin layer chromatography;
a.cellulose b.silica gel
c.aluminium oxide ​d.polyamide
33.In which limit test silver nitrate is used for producing opalescence
a.Limit test for sulphate b.Limit test of iron
c.Limit test for chloride​ ​ d.Limit test for Heavy metals
34.Quick identification of a compound is possible with the help of….
a.Mass spectra b.NMR spectra
c.​IR spectra​ ​ d.UV spectra
35.The titration of liberated iodine in chemical reaction is known as
a.Idometry​ ​ b.Iodimetry
c.Iodonometry d.All
36.The difference between measured value and true value is known as
a.Linearity b.Robustness
c.​Accuracy​ ​ d.Precision
37.The UV visible region in the electromagnetic spectrum of radiation is….
a.200-400 nm b.300-600 nm
c.​400-800 nm​ ​ d.200-800 nm
38.Colour of methyl orange indicator in alkali will be ….
a.Red b.Pink
c.Orange ​d.Yellow
39.TMS is used for the reference compound for …..
a.NMR spectroscopy​ ​ b.IR spectroscopy
c.Mass Spectroscopy d.UV spectroscopy
40.Which of the following element can not be analyzed with the help of flame photometer ?
a.Sodium b.Calcium
c.Potassium ​d.Cadmium
41.Carr price reaction is applied for the photometric evaluation of
a.Vitamin A b.Tocopherol
c.Nandrolone phenylpropionate d.Benzodiazepine
42.Peroxidase enzyme present in acacia is identified by
a.Borntrager's test
b.Molisch's test
c.Oxidation and excretion in benzene
d.Oxidation and treatment with benzidine

5. Pharmacist Model Qesution by Nabin Bist
43. Which of the following preparation is not for ocular use
a.Solution b.Suspension
c.Ointment d.Elixir
44.Dosages form have no systemic effect
a.Linctus b.Elixir
c.Solution d.Tincture
45.Suppositories should be stored in…..?
a.Cool place b.Cold place
c.Frozen condition d.Not specific
46.The maximum tolerance limit for a 500mg tablet as per pharmacopoeia is
a. 1%± ​ b. 5​%±
c. 7.5%± d. 10%±
47.Which of the following mechanical equipment can be used for emulsification?
a. Homogenizers b.Mechanical stirrers
c.Ultra sonifiers ​d.​ All
48.maximum disintegration time for uncoated tablet is
a.15 min ​ b.​30min
c.1hor d.60sec
49.Jellies are generally
a.​Water-soluble​ ​bases ​ ​ b.Water-insoluble bases
c.Both d. None
50.Liquid paraffin exhibits
a.Plastic flow b.Newtonian flow
c.Dilatant flow d​.​Pseudoplastic​ ​flow
51.Sodium stearyl fumarate is used as ;
a.Disintegrants ​b.​Lubricant
c.Glidant d.Binder
52.Approximate capacity of 000 capsule is
a.20mg b.200mg
c.900 mg d.​1500mg
53.Which of the following pharmaceutical additives is used in almost all of the edibles?
a.Cellulose b.Tragacanth
c.​Starch d.Acetone
54.HBL value is determined in case of
a.​Emulsion b.suspension
c.Tablets d.Elixir

6. Pharmacist Model Qesution by Nabin Bist
55.The abbreviation Ung means
a.Drop b.​Ointment
c.injection d.All
56.23.Suppositories are generally evaluated by
a.Melting range test b.Breaking test
c.Liquefaction d​.All the above
57.Flow rate of granules from the hopper can be improved by adding
a.​Glidant b.Lubricant
c.Binder d.All
58.Which ​of the following preparation must required sterility test
a.Suppositerary b.​Eye​ ​Drop
c.Oral drop d.suspension
59.Which drug will be affected most and quality may deteriorate if humidity is high in the
store?
a.Injection b.Liquid preparation
c.Ointment in aluminium tubes d.​Blister​ ​packed​ ​tablets
60.Starch in the startning of tablet formulation is
a.filler b.Diluents
c.​Binder d.Disintegrants
58.Which of the following polymer is widely used in film coating of tablets
a.Acacia b.Syrup
c.​HPMC d.Starch
59.Which tissue has the greatest capacity to biotransform of drugs?
a.Kidney b.​Liver
c.Lungs d.Skin
60. ___________is used to study gastric emptying
a​.​Barium​ ​sulphate b.Aluminium Sulphate
c.Calcium sulphate d.Aluminium hydroxide
61.Which of the following is carrier mediated transport system
a.diffusion b.​Active​ ​transport
c.transport d.None of the above
62.Choose the correct excipients for enhancing solubility in tablet manufacture
a.PEG b.​Microcrystalline​ ​cellulose
c.Talc d.Lactose
63.The time of peak serum concentration gives indication of the relative rate of
a.Absorption b.Distribution
c.Metabolism d.Excretion
64.what would be the order of greater to lesser bioavailability of the dosages forms

7. Pharmacist Model Qesution by Nabin Bist
a.Oral > Intravenous > Rectal > Topical
b.Intravenous > Rectal > Oral > Topical
c.Intravenous > Topical > Rectal > Oral
d.Intravenous > Oral > Rectal > Topical
65.Which glass apparatus is volumetric apparatus
a.Burette b.Separation funnel
c.Conical flask d.Beaker
66.Primary amines are incompatible with
a.Lactose b.Mannitol
c.Methyl cellulose d.Acacia
67.Orphan drug are
a.Very chief drug b.Placebo drug
c.OTC drug d.Drug used for treatment of rarer disease
68.Ondansetron is effective in the following types of vomiting
a.Cisplatin induced b.Radiotherapy induced
c​.​Postoperative d.All of the above
69.Alcoholic persons are at greater risk for………… deficiency
a.​Thiamine b.Riboflavin
c.Niacin d.Pyridoxine
70.Stevens johns syndrome is the most common adverse effect associated with one of the
following category of drug
a.​Sulphonamide b.Macrolides
c.Penicillins d.Tetracycline
71.Antidote of opioid analgesic is
a.Atropine b.Naloxone
c.Activated Charcoal d.All
72.Most frequent side effect of oral ampicillin is
a.Nausea and vomiting
b.​Loose motions
c.cOnstipation
d.Anorexia
73. L - DOPA is used for the treatment of
a.Tuberculosis b.​Parkinsonium​ ​Disease
c.Diabetes d.Cancer
74.Which one of the following is given parenterally?
a.​Iron-Dextran b.Ferric Ammonium citrate
c.Ferrous Fumarate d.Ferrous Sulphate

8. Pharmacist Model Qesution by Nabin Bist
75.Drug associated with risk factor of peptic ulcer
a.Metronidazole b.​Aspirin
c.Codeine d.Omeprazole
76.Which of the following drug is preferred in pregnancy related hypertension
a.Furosemide b.​Methyldopa
c.Propranolol d.Clonidine
77.Antidote of Organophosphorus poisoning is
a.Naloxone b.Deferoxamine
c.​Pralidoxime d.All
78.Choose one appropriate therapeutic use of imipramine
a.Insomnia b.Epilepsy
c.​Bed​ ​wetting in​ ​children d.Manina
79.Vitamin not found in foods of vegetable origin
a.​Vitamin​ ​B12 b.Vitamin B6
c.Vitamin B1 d.Vitamin B2
80.Mania is treated by
a.​lithium b.Prochlorperazine
c.Atropine d.None
81.Foetal Hydantoin syndrome is the teratogenic effect of which of the following drug
a.​Phenytoin b.Tetracycline
c.Aspirin d.All
82.The concentration of chlorhexidine in Nabimalam is…………
a.1% b.​2%
c.3% d.4%
83.Which of the following is the example of broad spectrum anthelmintics
a.​Albendazole b.Niclosamide
c.Pyrentral pymote d.Metronidazole
84.Fanconi syndrome is the side effect of
a.​Tetracycline b.Paracetamol
c.Vancomycin d.All
85.Which one of the following drug is CNS stimulant
a.Pilocarpine b.Acetylcholine
c.Adrenaline d.​Amphetamine
86.Which of the following dosages form should not be recommended for a patients who has a
an allergy to alcohol
a.Suspension b.​Elixir
c.Syrup d.None

9. Pharmacist Model Qesution by Nabin Bist
87.HIV infection can be clinically controlled with
a.Acyclovir b.​Zidovudine
c.Amantadine d.All of the above
88.The most powerful diuretics is
a.Spironolactone b.Hydrochlorothiazide
c.​Furosemide d.Amiloride
89.Ipratropium is mainly used in ………….
a.​COPD b.Epilepsy
c.Muscular pain d.Depression
90.Metallic taste is expressed by the use of ……..
a.Biguanides b.​Metronidazole
c.Albendazole d.Amoxycillin
91.Effect of oral contraceptive pills is inhibited by
a.Cimetidine b.Ethambutol
c.​Rifampicin d.Propranolol
92.The friability of uncoated tablet is
a.About 1% b.​Less​ ​than 1%
c.More than 1% d.none
93.Clinical function of hospital pharmacist may include except
a.Monitoring drug administration
b.Pharmacokinetics consultation
c.​Administration of medication
d.Making round with physician
94.One of the following drug synthesis is based on fischer indole synthesis
a.​Indomethacin b.Ibuprofen
c.Lignocaine d.Benzocaine
95.Which statements best describes how nitroglycerine relieves angina pain?
a.By reducing heart rate b.​By reducing preload
c.Vasodilation d.Vasoconstriction
96.Purpose of a combined drug regimen in tuberculosis
c.Schedule the onset of therapy
a.​Delay the emergence of drug resistance
b.Reduce the duration of active therapy
d.Promote the placebo effect on the patient
97.नेपाल तर नयामव ल २०४३ अनुसार हम न समुहको औस ध कु न समुहमा प ◌्न ?
a.समुह क b.समुह ख
c.समुह ग d.समुह घ

10. Pharmacist Model Qesution by Nabin Bist
98.Formulary is mainly
a.Treatment centered b.​Drug centered
c.Patient centered d.Manufacturing centered
99.Which of the following is not included in the definitions of Pharmacy profession in Nepal
pharmacy council act ?
a.Hospital Pharmacy b.Drug production
c.Quality control of Drug d​.Community Pharmacy
100.Standard of non pharmacopoeial drug is approved by ……
a.National Medicine Laboratory
b.Department of drug Administration
c.​Drug advisory committee
d.Drug consultative council
101.Which is not the function of pharmacy and therapeutic committee?
a.Develop hospital formulary
b.Initiate drug use review programme
c​.Procure medicine for the hospital
d.Advice pharmacy for drug distribution
102.A branch of the in-patient pharmacy responsible for preparing, dispensing, and
monitoring medications for specific patient areas
a.Pharmacy satellite b.Central pharmacy
c.Outpatient pharmacy d.all
103.Tetracycline are avoided during pregnancy because
a.It causes discoloration of mothers teeth
b.It is teratogenic
c.It may causes abortion
d.It may affect bone growth of fetus
104.The sweetest in the following list is
a.Sorbitol b.Saccharine
c.Cyclamate d.Mannitol
105.A Pharmacist should suggest to take plenty of water while dispensing…………..
a.Chlorpheniramine b.Promethazine
c​.Cotrimoxazole d.Loperamide
106.Infection by Helicobacter pylori , a short , spiral shaped , gram negative bacillus is the
leading cause of peptic ulcer disease (PUD) and is associated with virtually all ulcers not
induced by NSAIDs .The best treatment regimen among the following is
a.Ciprofloxacin 500mg / Lansoprazole 30 Mg / Amoxicillin 500 mg BID/ for 10 days
b.Penicillin V 500 mg / Lansoprazole 30 Mg / Clarithromycin 500mg BID for 14 days
c.Omeprazole 20 mg / Clindamycin 500mg / Amoxicillin 500 mg BID for 14 days

11. Pharmacist Model Qesution by Nabin Bist
d.Omeprazole 20 mg / Clarithromycin 500mg / Amoxicillin 1000 mg BID for 14 days
107.Which one of the following statement is true for metered dose inhaler ?
a.​Ejects a fixed amount of drug at one push
b.Ejects 100 mcg drug at a time
c.Gives a continuous of drug
d.Spray the drug from the container as required
108. Low dose Aspirin is widely used in cardiovascular disorder to………………..
a.Decrease the lipid level b.​Prevent​ ​platelets aggregates
b.Decreases synthesis of clotting factors d.All
109.Role of Hospital Pharmacist is
a.Drug formulary preparation and revision
b.Purchase , dispense and inventory control of medicines
c.Inspection of all pharmaceutical supplies in other department
d.all of the above
110.Which of the following is not the main role of community pharmacist?
a.Patient Education b.Patient Counselling
c.Drug Information d.​Therapeutic​ ​Drug Monitoring
111.The gas used in aerosol is called
a.​Propellant b.Solvent
c.Base d.All
112.APPON was established in
a.​1990 b.1972
c.1997 d.1986
113.औस धको ब ापन गन अनुम त लनुपन यव थाऔस ध एनको कु न दफामा उ लेख छ ?
a.दफा ९ b.दफा २२
c.दफा १९ d.दफा २६
114.फामसी प रसदमा रिज टार समेत क तजना सद य रहने यव था छ ?
a.८ b.९
c.१० d.११
115.The drugs may be classified into categories or subcategories as ​Ka . Kha . Ga​ in the
section ……………. Of drug act
a.15 B.16
c.17 d.31
116. Which one of the following is not component of drug management cycle
a.​Manufacturing b.Selection
c.Procurement d.Distribution

12. Pharmacist Model Qesution by Nabin Bist
117.नेपाल सरकार लाई औस ध स बि ध शैदाि तक तथा शास नक बषयमा परामश कु न सं था ले
दने गदछ ?
a.औस ध स लहाकार स म त b.नेपाल फामसी प रसद
c.औस ध यव था बभाग d.औस ध परामस स म त
118.Logistic management of drug is related to
a.The management of procurement supply and distribution of drugs
b.Quality control of drugs
c.Registration of drugs
D.marketing of drugs
119.How many parts of 10% ointment to be mixed with 2 parts of 15% ointment to get 12%
ointment ?
a.2 b.​3
c.5 d.6
120.The total section of drug act 1978 are
a.34 b.7
c.33 d.​40
121.औष ध एन क त सालमा बनेको हो?
a.२०३३ b.२०३४
c.​२०३५ d.२०३८
122.नेपाल सरकारले हालसालै क तवटा औष धको अ धकतम खु ा मु य तोके को छ?
​ a.​९६ b.९७
c.९८ d.९९
123.Pharmacopoeias could be a vital reference tool for people and organization involved in
pharmaceutical
a.Research b.Development
c. Quality control and analysis ​d.​All
124.Which of the following drug is band in Nepal except
​a.​Phenylbutazone b.Amphetamine
c.Meprobamate d.Tetracycline liquid
125.When National drug policy was introduced in Nepal .
a.1972 b.1990
c.1991 d.​1995
126.National list of essential drug of Nepal was prepared in
a.​1986​ b.1970
c.1972 d.None
127.Provision of clinical trial is related to which section of drug act 2035
a.section 25 b.section 17
c.section 26 ​d.Section 31

13. Pharmacist Model Qesution by Nabin Bist
128.Which of the following pharmacopoeia is not official of Nepal
a.BP ​b.Chinese pharmacopeia
c.USP d.IP
129.Drug sale and distribution code 2041 BS was phased out in
​ a.2071 BS​ ​ b.2072 BS
c.2070 BS d.2073 BS
130.Which is the prime focus of pharmaceutical care?
a.The pharmacist b.The prescription
​c​.The patient​ d.The patient chart
131.Effective management of drug will
a.Ensure constant supply
b.Minimize wastage of resources
c.Reduce price of drug
d​.All of the above
132.What makes pharmacist unique in the health care team?
a.Pharmacist advise patients on how to take their medicines
b.Pharmacist are exports on communicating with patients and other health care
c.Pharmacist have access to a vast amount of knowledge on medicines and the actions
of drug
​ ​d.Pharmacist are experts on medicine formulation and use and can apply this to
patients care
133.Which factor is not related to the important criteria for proper drug use?
a.Correct dispensing and suitable packing
b.Rational drug prescribing and patient compliance
c.Accurate diagnosis
​d.Promotional literature presentation
134.Common errors for patients compliance is
a.Timing or sequence
b.Omission
c.Premature termination of drug therapy
​ ​d.All of the above
135.During handling the prescription in the pharmacy , the responsibility of the pharmacist
should be,
a.Feel the attendance to the patient
b.Make comfortable
c.Encourage to well soon
​d.All the above
136.​All of the following are the aims of first aid except
a.To preserve life b.To promote recovery

14. Pharmacist Model Qesution by Nabin Bist
c.To prevent further damage ​d.To cure the diseases
137.The following drugs fall under antihistamine category except
a.Cetrizine b.Pseudoephedrine
c.Chlorpheniramine ​ ​d.Terfenadine
138.Which one of the following is not the core role of a dispensing community pharmacist?
a.Checking on the appropriateness of the medicine
b.Keeps medication records
c.providing education to the other health professionals
​d.Monitors adherence to the therapy
139. Which one of the following is not the ethics of a pharmacist?
a.To respect the rights of individual patients to participate in decisions
​b.To give priorities to the high official in pharmacy service
c.To collaborate with other health professionals
d.All
140……………. Communication will find a mutually acceptable solution
​a.An assertive ​ ​ b.A aggressive
c.A passive aggressive d.A submissive
141.Patient taking antihistamine should be advised for…..
​a.Not to drive till the period you take medicine
b.Take plenty water
c.Take after food
d.Take before meal
142.Environmental monitoring in pharmaceutical industry is…….
a​.One of the methods of sterilization
b.required for documenting load of microorganism in facility
c.required for disinfection procedure
d.one of the methods of antibiotic assay
143.Following are the barriers of effective communication except …….
a.Environment b.Law regarding pharmacy practice
c.Time d.pharmacist
144.If 10 mg of naproxen produces the same analgesic response as 100 mg of ibuprofen,
which of the following statements is correct?
a.Naproxen is more efficacious than is ibuprofen.
b.Naproxen is more potent than ibuprofen.
c.Naproxen is a full agonist, and ibuprofen is a partial agonist.
d.Naproxen is a better drug to take for pain relief than is ibuprofen.
145.The first process to occur before a drug is available for absorption from an oral tablet is
a.Dissolution of the drug in GI fluids
b.Dissolution of drug in GI Epithelium

15. Pharmacist Model Qesution by Nabin Bist
c.Ionization of the drug
d​.Disintegration of tablet
146.All of the following statements are true except
a.Good pharmacy practice (GPP) requires evidence based care
b.GPP promotes rational and economic prescribing
c.GPP promotes generic prescribing
d.GPP require that the objective of each element of pharmacy serve is relevant to the
patient
147.Patients should be advised to shake the bottle before use while dispensing ……..
​a.Suspension​ ​ b.Tablet
c.Solution d.All
148.What do you mean by abbreviations HS ?
​a.At bed time​ ​ b.Between meals
c.When necessary d.In the afternoon
149.Nepal pharmacy council act was promulgated by government of Nepal in;
a.2058 BS b.​2057​ BS
c.2055 BS d.2056 BS
150.One of the following documents is not included in the list required for community
pharmacy ;
a.Quality manual b.protocols
c.SOP ​d.GMP Audit report
Nabin Bist
Patan Academy of Health science
Zenith study center