Smartphone-powered Ophthalmic Diagnostics

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Overview of the emerging field of smartphone-powered ophthalmic diagnostics that has the potential to bring down the cost and improve access to healthcare especially in developing countries. Alternative download link: https://www.dropbox.com/s/c3ef13nlw2mywa7/iphoneFundusCamera.pdf?dl=0

Devices & Hardware

SMARTphone OPHTHALMIC DIAGNOSTICS
Startups and optical designs
Petteri Teikari, PhD
http://petteri-teikari.com/
version Fri 1 September 2017

Smartphone fundus cameras #1
http://www.odocs-tech.com/
http://www.peekvision.org/
d-eyecare.com
ophthalmicdocs.com
OPEN-SOURCECOMMUNITY

Smartphone fundus cameras #2
volk.com
medisave.co.uk

PORTABLE/SMARTPHONE fundus cameras #3
Why would you need someone else
to take a picture of your own eye?
http://web.media.mit.edu/~tswedish/projects/eyeSelfie.html
http://www.optomed.com/

OPHTHALMOLOGICAL OPTICS
A The human eye as an optical system (Sliney 2005)
- estimates of human eye focal length f
vary between 17-24 mm, see e.g.
hypertextbook.com (f = 22.3 mm standardized
result)
B Photoreceptor optics (Warrant and Nilsson 1998)

SMARTPHONE SENSOR&OPTICS
anandtech.com
dpreview.com
anandtech.com
“Easiest to design to iPhones as the optomechanics are the same, whereas with
different Android phones, the optics should be customized to each model”

OPTICAL DESIGNS #1
Giardini et al. (2014)
[PDF]
Fang et al. (2015)

OPTICAL DESIGNS #2
Exploded view of the D-Eye module (angles and distances
between components are approximated). Retinal images are
acquired using coaxial illumination and imaging paths thanks to a
beam splitter (C). The blue arrow depicts the path of the light;
red arrow depicts the path of fundus imaging. Device
components are glass platelet (A) with imprinted negative lens (A
′), photo-absorbing wall (B), beam splitter (C), mirror (D), plastic
case (E), diaphragm (F), polarized filters (G, H), flash and camera
glass (J, I), and magnetic external ring (K). Russo et al. (2015)

OPTICAL DESIGNS #3
http://web.media.mit.edu/~tswedish/projects/eyeSelfie.html
“The subject aligns his/her
own for optimal image”

OPTICAL DESIGNS #4
Bergeles et al. (2015)

OPTICAL DESIGNS #5
3ders.org
3D print your own parts, or have them printed for you at Shapeways

OPTICAL DESIGNS #6
https://hackaday.io/project/11943-open-indirect-ophthalmoscope
Including CAD files for 3D Printing
g and Eagle files for the PCB design

Medical optics Small-scale micro-optics
http://nanocomp.fi/what-we-do/applications/healthcare/
https://www.luxexcel.com/portfolio/microstructures-micro-optics/
3D printed custom microstructures and micro optics, LUXeXceL
http://dx.doi.org/10.1038/nphoton.2016.121 Two-photon direct
laser writing of ultracompact multi-lens objectives

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