imaginal disc formation n control in drosophila

1. GENE EXPRESSION FOLLOWING INDUCTION OF REGENERATION IN DROSOPHILA WING IMAGINAL DISCS AND EXPRESSION PROFILE OF REGENERATING WING DISCS.

8. METHODS AND MATERIALS

16. Results and Discussion

17. Whole genome expression analysis of intact and regenerating wing discs

19. Total number of up and downregulated genes in NC0->NC24, C0->C24 and C24->C72 microarrays. NC0 ->NC24 C0 ->C24 C24 ->C72 GENES (UP) 407 607 116 GENES (DOWN) 356 576 165 TOTAL 763 1183 281

26. IDENTIFICATION OF GENES WITH PUTATIVE ROLES IN REGENERATION

31. Classification of differentially expressed genes involved in wing imaginal disc regeneration .

40. Transcriptional regulators acting in early and late regeneration

42. JNK signalling pathway- a necessary step in regeneration

50. Requirement of transcription factors and chromatin remodelers in regeneration

54. The transcription factor Cbt as an example of Class III genes

58. CONCLUSIONS

62. Thank you