Presentation on DHL by Ali Kocer during the SMB/Health Valley meeting on September 27, 2018 at Novio Tech Campus in Nijmegen, NL.

1. PUBLIC
FROM MOLECULE TO BUSINESS -
DEVELOPING THE SUPPLY CHAIN
DELIVERING HEALTHCARE TO THE WORLD
Ali Koçer – Business Development Manager DHL Supply Chain Benelux - LSH
Nijmegen, Netherlands - 27 September 2018
1

2. PUBLIC
Overview DHL
Group and
DHL Supply Chain
Life Sciences and
Healthcare (LSH)
Business Unit
From Molecule to
Business - Developing
The Supply Chain
AGENDA
2
Delivering Healthcare to the World

3. PUBLIC
Post - eCommerce
Parcel (PeP)
Nº 1 in post services and e-
commerce delivery
DHL GROUP
D P D H L
Express
Nº 1 in international express
shipments
Global Forwarding
Freight
Leader in international transport
services
Supply Chain
Nº 1 in contract logistics
The divisions of the DPDHL Group offer extended logistical services, with specific solutions
for each need in the entire Supply Chain
3

4. PUBLIC
O v e r v i e w i n n u m b e r s
DPDHL GROUP
+60.000 Mil.€ +500.000 +90.000 +30 Mil.m2
Turnover in 2017 Employees Vehicles Warehousing
+220
Countries
+250Aircrafts
4

5. PUBLIC
+ 4.100
+21
Logistics specialists
Warehouses in
the Benelux
DHL SUPPLY CHAIN:
T h e b i g g e s t c o n t r a c t l o g i s t i c s s e r v i c e
p r o v i d e r i n B e n e l u x a n d t h e W o r l d
+1Mil m2
Warehouse
space
Presence of DHL Supply Chain
Presence of other divisions of Deutsche Post DHL Group
148.000
1.469
Logistics
specialists
*Figures as at June 30th, 2018
Warehouses
in the world
13 Mil m2
Warehouse
space
5

6. PUBLIC
DHL SUPPLY CHAIN - LIFE SCIENCES & HEALTHCARE
T h e b i g g e s t l i f e s c i e n c e s a n d h e a l t h c a r e l o g i s t i c s s e r v i c e
p r o v i d e r i n B e n e l u x
Presence of DHL Supply Chain
Presence of other divisions of Deutsche Post DHL Group
~ 10.000
+180
Logistics
specialists
Warehouses
in the world
+2 Mil m2
Warehouse
space
+ 700
+6
Logistics specialists
Warehouses in
the Benelux
+100.000 m2
Warehouse
space
+ 80
Customers
+ 700
+6
Logistics specialists
Warehouses in
the Benelux
+100.000 m2
Warehouse
space
+ 80
Customers
Regulation
• All Pharma licensed
• GDP
• GMP (Limited Manufacturing License)
• ISO 9001
• ISO 14001
• ISO 13485
Medical devicesPharmaceuticals
SUB-SECTORS
LSH GMP facility LSH facility
Clinical trials Hospitals & health
services
Boortmeerbeek
Nijmegen (2)
Veghel
Facility grading
G S B
Laekebeek
Huizingen&Lot
SOLUTIONS
Transport
• Managed Ground Transport
Warehousing
Management Services
• Procurement Services
Integrated Solutions
• Lead Logistics Partner
• Logistics Consulting
• DHL HealthConnect
• Service Logistics
Specialist expertise
• Medical Devices Final Mile
Logistics
Additional Services
• Packaging Services
15 – 25°C
2 – 8°C
-20°C
-80°C
Ambient
6

7. PUBLIC
Overview DHL
Group and
DHL Supply Chain
Life Sciences and
Healthcare (LSH)
Business Unit
From Molecule to
Business - Developing
The Supply Chain
From Molecule to Business -
Developing Supply Chain Services
7
Delivering Healthcare to the World

8. PUBLIC
Industry Challenges
P h a r m a c e u t i c a l s
P h a r m a c e u t i c a l s
 B i o - t e c h
 P a t e n t e d P h a r m a
 G e n e r i c s
 A n i m a l H e a l t h
 C o n s u m e r H e a l t h
B i o - t e c h I n d u s t r y D y n a m i c s & C h a l l e n g e s
 Specialty/orphan drug/biological revolution with higher values, smaller lots/ fewer customers
(specialty clinics, orphan patients), more sensitive product
 Cold chain remains key
 Opportunity to ‘own’/manage direct to hospital/ patent for top clinics globally
 Continuity of supplies more important (due to immunogenicity challenges)
 Continued globalization: access to markets globally remains important
 Continued regulatory tightening, e.g., Serialization, EU GDP, customer compliance, and
counterfeiting pressure  Regulatory compliance is key
Cost pressure: (1) Pricing pressure/ value based reimbursement, (2) Bio-similar emerging
depending on product portfolio
 Limited opportunity for stock level reductions  consider postponement
 Tax optimization requires product to physically pass through countries with tax advantages (e.g.
Netherlands, Singapore)
8

9. PUBLIC
9
Solutions Across the Entire Supply Chain
As the world’s leading contract logistics specialist, we offer a comprehensive suite of services drawing on our global scale and local
insight to deliver value across your supply chain.
DHL Managed Transport &
Brokerage
DHL Inbound Transport
Operations
DHL Outbound Transport
Operations
Transport Solutions
DHL Warehousing
DHL Real Estate Solutions
Warehousing Solutions
DHL Logistics Consulting
DHL Procurement Services
DHL Recall Services
DHL Business Support
Center
Management Services
DHL Lead Logistics Partner
DHL Inbound to
Manufacturing
DHL Service Logistics
DHL Indirect Materials
Management (MRO)
DHL Passenger
Gateway Services
DHL Envirosolutions
DHL HealthConnect
DHL Clinical Trials
DHL Fulfillment
Integrated Solutions
DHL Packaging Services
DHL Pre-Sales Services
DHL In-plant Logistics
Additional Services

10. PUBLIC
Integrated Solutions
H e a l t h C o n n e c t
10
Providing direct to market access to increase patient satisfaction
A direct-to-market solution enabling DHL’s healthcare
customers to bypass traditional distributors and trade
directly with their end customers, using DHL as an
agent. It provides a standardized bundle of fulfillment and
distribution services fully integrated with multi-channel order
management and accounts receivable capabilities.
Customer benefits
 Enables direct to market sales channels
 Provides transparency and detailed sales information
 Increases security with less handling and lower chances of
counterfeiting
 Increases profit by cutting out wholesaler margins
 Gives you complete control over service and shipping
conditions
Characteristics
 Standardized Warehousing
Management
 Ambient and temperature-controlled
facilities
 Single or multi-location storage and
inventory management
 Integrated Transportation
Management with domestic and
international shipping
 Full Order to Cash B2B solution
 Call center and customer services
 Real-time order and shipment
tracking with Proof of Delivery
 Delivery/return order management
 Pre-built integration reducing
implementation time and cost

11. PUBLIC
Specialist Services
P a c k a g i n g & L a b e l l i n g
11
Postponement is the business strategy that delays product differentiation at
a point closer to the customer and maximizes possible benefits
• Patient centric solution for high value, small
volume products
• Reduced finished product stock levels
• Reduced lead times
• Temperature Assurance and Traceability (E2E)
• Supply chain integrator between manufacturer
and final customers
• Provides the last controllable stock holding
location before the medicine goes to customers
• Optimizes E2E supply chain
Late specification
of product
Dispatch
Mass
production
Goods stored
Order for
specific good
Traditional scope
Goods-in
Goods
picked
Industry requirements DHL role
TraditionalDHL extended focus today

12. Questions
12

14. Backup
14

15. PUBLIC
Nijmegen Campus
Veghel
Huizingen & Lot
Laekebeek
Boortmeerbeek
DHL Supply Chain Benelux LSH Facilities
15
3 4 . 2 0 0 m 2
GDP/GMP/ISO 13485
GDC/RDC Pharma &
Medical Devices
9 . 5 5 5 m 2
ISO 13485
GDC/RDC Medical
Devices
2 1 . 0 8 1 m 2
GDP
Pharma Export Hub
&Benelux Distribution
55.000 m2
Pharma & Medical
Devices Grade
26.000 m2
Pharma & Medical
Devices Grade
17.801 & 11.302 m2
GDP/GMP
Pharma Benelux Dist.
Upcoming Project!

16. PUBLIC
Our services range from
Global/European supply
chain management, to
local pre-wholesale
activities in Benelux . We
are the market leader in
prescriptive drugs
distribution in Benelux
and an important service
provider to the MedDev
industry.
Our operations meet
international & local
regulations, with specific
focus on temperature
assurance/validation &
security.
We have necessary licenses
in place, including
GDP&GMP as well as Pre-
Wholesale licenses.
Highly experienced
organization specialized in
LSH operations.
Our experienced LSH
team bring a wide
industry knowledge,
driving innovation for
and with our customers.
Our recent innovative
solutions include: global
direct-to-hospital,
end-to-end sample
management,
postponement, live
active airline tracking
and many others.
We focus on LSH only. Our
customers are global
industry leaders and local
market specialists.
Our customer base include
manufacturers of medical
devices, OTC, beauty-care
products, prescriptive drugs
and biotech/specialty
pharmaceuticals.
Being a leader in LSH logistics services in Benelux, we
focus on further growth an innovation in our industry...
16

17. PUBLIC
Site Profile N i j m e g e n
17
34.400 m2
+24.500 pallet positions, 20 docks / 2 doors
~240 FTE + ~90 temp. staff
ISO9001:2008, ISO13485:2003, ISO14001:2004, AEO-F,
GDP, GMP
Distribution to >1 000 customers, >100 local DC’S
and to more than >100 countries
F a c t s & f i g u r e s
Storage (including cold and hazardous, as well as bonded / non-bonded)
and international distribution of pharmaceutical products, medical
devices, biotechnology & diagnostics.
 EDC and regional service
concepts
 Transport management
 Customs management (E-
licensed)
 Clinical Trials Logistics
 Order to Cash
 Control Tower
 24/7 emergency delivery
Service
 Wholesale dealers licence
 Pharmacists on site
 Limited Manufacturing licensed
 Controlled drugs license
 Multi-lingual Customer Service
 Cold Chain
 GMP and GDP compliance
 In house Customs Department
 In house Transportation
Department
 Security: Restricted Access,
CCTV and fence.
Value Added services
 Relabeling
 Kitting
 Repacking
 Display building
 Production postponement
 Contract packaging
 Promotional activities
 Return & Repair
 Configuration
 Battery Replacement
 Testing
S e r v i c e s P r o v i d e d
N i j m e g e n C a m p u s
~55.000 m2
+50.000 pallet positions
~300 FTE + ~100 temp. staff
ISO9001:2008, ISO13485:2003, ISO14001:2004, AEO-F,
GDP, GMP
Distribution to >1 000 customers, >100 local DC’S
and to more than >100 countries
Storage (including cold and hazardous, as well as bonded / non-bonded)
and international distribution of pharmaceutical products, medical
devices, biotechnology & diagnostics.
 EDC and regional service
concepts
 Transport management
 Customs management (E-
licensed)
 Clinical Trials Logistics
 Order to Cash
 Control Tower
 24/7 emergency delivery
Service
 Wholesale dealers licence
 Pharmacists on site
 Limited Manufacturing licensed
 Controlled drugs license
 Multi-lingual Customer Service
 Cold Chain
 GMP and GDP compliance
 In house Customs Department
 In house Transportation
Department
 Security: Restricted Access,
CCTV and fence.
Value Added services
 Relabeling
 Kitting
 Repacking
 Display building
 Production postponement
 Contract packaging
 Promotional activities
 Return & Repair
 Configuration
 Battery Replacement
 Testing

18. PUBLIC
The future of Life Sciences and Healthcare Logistics
1
2
3
4
5
6
7
8
9
Augmented reality1.
Advanced Analytics2.
Internet of Things3.
AGVs4.
Collaborative Robots5.
Serialization tags6.
UAVs7.
Online drug orders
Direct-to-home
Deliveries
8.
On Demand Delivery9.
W e m a k e u s e o f n e w t e c h n o g i e s t h a t a r e s h a p i n g o u r i n d u s t r y
a n d w e a r e w i l l i n g t o w o r k i n c o o p e r a t i o n w i t h X X X t o
i m p l e m e n t a n y o f t h e s e t e c h n o l o g i e s t o o u r s o l u t i o n .
18

19. PUBLIC
Specialist Services
S e r i a l i z a t i o n
19
CMO: printing,
labelling, packing
incl. serialization
Distribution/
Dispatch
Mass
production
Goods stored
Order for
specific good
Traditional DHL scope
Goods-in
Goods
picked
TraditionalDHL extended focus today
Printing Packing services Aggregation
• Printing serial number on a
package or label (and then
applying a label on product/
package)
• Assembling final
presentations (packaging &
labelling) into a unit package,
sealing the pack and
scanning package
information
• Building a “parent-child”
relationship between unique
identifiers assigned
to packaging units, bundles,
cases, and pallets
1a 1b 1c
and/or and/or

20. PUBLIC
20
Customer benefits
• Regulatory Compliance
• Standard operations and one IT solution
• Cost effectiveness through multi client
solutions
• Flexible/modular approach to meet
requirements across different markets
1
2
3
4
DHL
Serialization
platform
C o r e s e r v i c e s
p e r f o r m e d a s
o n e s t a n d a r d
g l o b a l l y
Inbound: Serial no. capture using aggregation1
Outbound: Serial no. capture & validation2
Aggregation/re-aggregation3
Serial number decommissioning & verification4
FULL T&T Serialization Solution